메뉴 건너뛰기




Volumn 1, Issue 2, 2000, Pages 180-188

Aerosol Delivery of Robust Polyethyleneimine- DNA Complexes for Gene Therapy and Genetic Immunization

Author keywords

Aerosol; Cationic lipid; Genetic immunization; Guanidinium cholesterol; Instillation; Nebulization; Nonviral vector; Nose; Polyethyleneimine; Pulmonary delivery

Indexed keywords

CATION; DNA; LIPID; POLYETHYLENEIMINE;

EID: 0034136169     PISSN: 15250016     EISSN: None     Source Type: Journal    
DOI: 10.1006/mthe.1999.0021     Document Type: Article
Times cited : (159)

References (28)
  • 1
    • 0029815814 scopus 로고    scopus 로고
    • Plasmid DNA molecules complexed with cationic liposomes are protected from degradation by nucleases and shearing by aerosolization
    • Crook K., McLachlan G., Stevenson B. J., Porteous D. J. Plasmid DNA molecules complexed with cationic liposomes are protected from degradation by nucleases and shearing by aerosolization. Gene Ther. 3:1996;834-839.
    • (1996) Gene Ther. , vol.3 , pp. 834-839
    • Crook, K.1    McLachlan, G.2    Stevenson, B.J.3    Porteous, D.J.4
  • 5
    • 0031976062 scopus 로고    scopus 로고
    • Aerosolization of cationic lipid:pDNA complexes - In vitro optimization of nebulizer parameters for human clinical studies
    • Eastman S. J., Tousignant J. D., Lukason M. J., Chu Q., Cheng S. H., Scheule R. K. Aerosolization of cationic lipid:pDNA complexes - In vitro optimization of nebulizer parameters for human clinical studies. Hum. Gene Ther. 9:1998;43-52.
    • (1998) Hum. Gene Ther. , vol.9 , pp. 43-52
    • Eastman, S.J.1    Tousignant, J.D.2    Lukason, M.J.3    Chu, Q.4    Cheng, S.H.5    Scheule, R.K.6
  • 6
    • 0030974582 scopus 로고    scopus 로고
    • Pulmonary surfactant inhibits cationic liposome-mediated gene delivery to respiratory epithelial cells in vitro
    • Duncan J. E., Whitsett J. A., Horowitz A. D. Pulmonary surfactant inhibits cationic liposome-mediated gene delivery to respiratory epithelial cells in vitro. Hum. Gene Ther. 8:1997;431-438.
    • (1997) Hum. Gene Ther. , vol.8 , pp. 431-438
    • Duncan, J.E.1    Whitsett, J.A.2    Horowitz, A.D.3
  • 7
    • 0030957838 scopus 로고    scopus 로고
    • Surfactant inhibits cationic liposome-mediated gene transfer
    • Tsan M.-F., Tsan G. L., White J. E. Surfactant inhibits cationic liposome-mediated gene transfer. Hum. Gene Ther. 8:1997;817-825.
    • (1997) Hum. Gene Ther. , vol.8 , pp. 817-825
    • Tsan, M.-F.1    Tsan, G.L.2    White, J.E.3
  • 8
    • 0033154811 scopus 로고    scopus 로고
    • Gene transfer by guanidinium-cholesterol:dioleoylphosphatidyl-ethanolamine liposome-DNA complexes in aerosol
    • Densmore C., Giddings T., Waldrep J. C., Kinsey B. M., Knight V. Gene transfer by guanidinium-cholesterol:dioleoylphosphatidyl-ethanolamine liposome-DNA complexes in aerosol. J. Gene Med. 1:1999;251-264.
    • (1999) J. Gene Med. , vol.1 , pp. 251-264
    • Densmore, C.1    Giddings, T.2    Waldrep, J.C.3    Kinsey, B.M.4    Knight, V.5
  • 10
    • 0030462391 scopus 로고    scopus 로고
    • Optimized galenics improve in vitro gene transfer with cationic molecules up to 1000-fold
    • Boussif O., Zanta M. A., Behr J.-P. Optimized galenics improve in vitro gene transfer with cationic molecules up to 1000-fold. Gene Ther. 3:1996;1074-1080.
    • (1996) Gene Ther. , vol.3 , pp. 1074-1080
    • Boussif, O.1    Zanta, M.A.2    Behr, J.-P.3
  • 11
    • 0026094167 scopus 로고
    • A novel cationic liposome reagent for efficient transfection of mammalian cells
    • Gao X., Huang L. A novel cationic liposome reagent for efficient transfection of mammalian cells. Biochem. Biophys. Res. Commun. 179:1991;280-285.
    • (1991) Biochem. Biophys. Res. Commun. , vol.179 , pp. 280-285
    • Gao, X.1    Huang, L.2
  • 13
    • 19244363903 scopus 로고    scopus 로고
    • Detailed analysis of structures and formulations of cationic lipids for efficient gene transfer to the lung
    • Lee E. R., Marshall J., Siegel C. S. Detailed analysis of structures and formulations of cationic lipids for efficient gene transfer to the lung. Hum. Gene Ther. 7:1996;1701-1717.
    • (1996) Hum. Gene Ther. , vol.7 , pp. 1701-1717
    • Lee, E.R.1    Marshall, J.2    Siegel, C.S.3
  • 14
    • 0032559535 scopus 로고    scopus 로고
    • Pulmonary pharmacokinetics of cyclosporin A liposomes
    • Arppe J., Vidgren M., Waldrep J. C. Pulmonary pharmacokinetics of cyclosporin A liposomes. Intl. J. Pharm. 161:1998;205-214.
    • (1998) Intl. J. Pharm. , vol.161 , pp. 205-214
    • Arppe, J.1    Vidgren, M.2    Waldrep, J.C.3
  • 16
    • 0024282306 scopus 로고
    • Evidence for targeted gene delivery to Hep G2 hepatoma cells in vitro
    • Wu G. Y., Wu C. H. Evidence for targeted gene delivery to Hep G2 hepatoma cells in vitro. Biochemistry. 27:1988;887-892.
    • (1988) Biochemistry , vol.27 , pp. 887-892
    • Wu, G.Y.1    Wu, C.H.2
  • 17
    • 0030775528 scopus 로고    scopus 로고
    • The influence of polymer structure on the interactions of cationic polymers with DNA and morphology of the resulting complexes
    • Tang M. X., Szoka F. C. The influence of polymer structure on the interactions of cationic polymers with DNA and morphology of the resulting complexes. Gene Ther. 4:1997;823-832.
    • (1997) Gene Ther. , vol.4 , pp. 823-832
    • Tang, M.X.1    Szoka, F.C.2
  • 18
    • 0027655718 scopus 로고
    • Functionalization of polyamidoamine cascade polymers and their use for efficient transfection of cells in culture
    • Haensler J., Szoka F. C. Functionalization of polyamidoamine cascade polymers and their use for efficient transfection of cells in culture. Bioconj. Chem. 4:1993;372-379.
    • (1993) Bioconj. Chem. , vol.4 , pp. 372-379
    • Haensler, J.1    Szoka, F.C.2
  • 20
    • 0031788165 scopus 로고    scopus 로고
    • The size of DNA/transferrin-PEI complexes is an important factor for gene expression in cultured cells
    • Ogris M., Steinlein P., Kursa M., Mechtler K., Kircheis R., Wagner E. The size of DNA/transferrin-PEI complexes is an important factor for gene expression in cultured cells. Gene Ther. 5:1998;1425-1433.
    • (1998) Gene Ther. , vol.5 , pp. 1425-1433
    • Ogris, M.1    Steinlein, P.2    Kursa, M.3    Mechtler, K.4    Kircheis, R.5    Wagner, E.6
  • 21
    • 0032938324 scopus 로고    scopus 로고
    • PEGylated DNA/transferrin-PEI complexes: Reduced interaction with blood components, extended circulation in blood and potential for systemic gene delivery
    • Ogris M., Brunner S., Schuller S., Kircheis R., Wagner E. PEGylated DNA/transferrin-PEI complexes: Reduced interaction with blood components, extended circulation in blood and potential for systemic gene delivery. Gene Ther. 6:1999;595-605.
    • (1999) Gene Ther. , vol.6 , pp. 595-605
    • Ogris, M.1    Brunner, S.2    Schuller, S.3    Kircheis, R.4    Wagner, E.5
  • 22
    • 0031720533 scopus 로고    scopus 로고
    • Polyethyleneimine-based intravenous delivery of transgenes to mouse lung
    • Goula D., Benoist C., Mantero S., Merlo G., Levi G., Demeneix B. A. Polyethyleneimine-based intravenous delivery of transgenes to mouse lung. Gene Ther. 5:1998;1291-1295.
    • (1998) Gene Ther. , vol.5 , pp. 1291-1295
    • Goula, D.1    Benoist, C.2    Mantero, S.3    Merlo, G.4    Levi, G.5    Demeneix, B.A.6
  • 24
    • 0032571392 scopus 로고    scopus 로고
    • Polyethyleneimine but not cationic lipids promotes transgene delivery to the nucleus in mammalian cells
    • Pollard H., Remy J.-S., Loussouarn G., Demolombe S., Behr J.-P., Escande D. Polyethyleneimine but not cationic lipids promotes transgene delivery to the nucleus in mammalian cells. J. Biol. Chem. 273:1998;7507-7511.
    • (1998) J. Biol. Chem. , vol.273 , pp. 7507-7511
    • Pollard, H.1    Remy, J.-S.2    Loussouarn, G.3    Demolombe, S.4    Behr, J.-P.5    Escande, D.6
  • 25
    • 0033609001 scopus 로고    scopus 로고
    • Tracking the intracellular path of poly(ethyleneimine)/DNA complexes for gene delivery
    • Godbey W. T., Wu K. K., Mikos A. G. Tracking the intracellular path of poly(ethyleneimine)/DNA complexes for gene delivery. Proc. Natl. Acad. Sci. USA. 96:1999;5177-5181.
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 5177-5181
    • Godbey, W.T.1    Wu, K.K.2    Mikos, A.G.3
  • 27
    • 0033122034 scopus 로고    scopus 로고
    • Transfection and physical properties of various saccharide, poly(ethylene glycol), and antibody-derivatized polyethylenimines (PEI)
    • Erbacher P., Bettinger T., Belguise-Valladier P., Zou S., Coll J. L., Behr J. P., Remy J. S. Transfection and physical properties of various saccharide, poly(ethylene glycol), and antibody-derivatized polyethylenimines (PEI). J. Gene Med. 1:1999;210-222.
    • (1999) J. Gene Med. , vol.1 , pp. 210-222
    • Erbacher, P.1    Bettinger, T.2    Belguise-Valladier, P.3    Zou, S.4    Coll, J.L.5    Behr, J.P.6    Remy, J.S.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.