메뉴 건너뛰기




Volumn 16, Issue 9, 2001, Pages 1854-1860

RASA, a recombinant single-chain variable fragment (scFv) antibody directed against the human sperm surface: Implications for novel contraceptives

Author keywords

Agglutination; Antibody engineering; Contraception; Recombinant antibody; Single chain Fv

Indexed keywords

CARBOHYDRATE; CD52 ANTIGEN; COMPLEMENTARY DNA; CONTRACEPTIVE AGENT; EPITOPE; HUMAN SPERM AGGLUTINATION ANTIGEN 1; IMMUNOGLOBULIN KAPPA CHAIN; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY S19; MONOMER; POLYMER; RECOMBINANT ANTIBODY; RECOMBINANT SPERM ANTIBODY; SPERM ANTIBODY; SPERM ANTIGEN; UNCLASSIFIED DRUG;

EID: 0034803883     PISSN: 02681161     EISSN: None     Source Type: Journal    
DOI: 10.1093/humrep/16.9.1854     Document Type: Article
Times cited : (33)

References (45)
  • 9
    • 0028143333 scopus 로고
    • Monoclonal antibodies for reproductive health: Part I. Preventing sexual transmission of disease and pregnancy with topically applied antibodies
    • (1994) Am. J. Reprod. Immunol. , vol.32 , pp. 114-131
    • Cone, R.A.1    Whaley, K.J.2
  • 21
    • 0023105575 scopus 로고
    • Establishment and characterization of a human hybridoma secreting monoclonal antibody with high titers of sperm immobilizing and agglutination activities against human seminal plasma
    • (1987) J. Reprod. Immunol. , vol.10 , pp. 67-78
    • Isojima, S.1    Kameda, K.2    Tsuji, Y.3
  • 22
    • 0345044918 scopus 로고    scopus 로고
    • Domain interactions in antibody Fv and scFv fragments: Effects on unfolding kinetics and equilibria
    • (1999) FEBS Letters , vol.462 , pp. 307-312
    • Jager, M.1    Pluckthun, A.2
  • 27
    • 0028294931 scopus 로고
    • Recombinant anti-sialidase single-chain variable fragment antibody. Characterization, formation of dimer and higher-molecular mass multimers and the solution of the crystal structure of the single-chain variable fragment/sialidase complex
    • (1994) Eur. J. Biochem. , vol.221 , pp. 151-157
    • Kortt, A.A.1    Malby, R.L.2    Caldwell, B.3
  • 28
    • 0031895791 scopus 로고    scopus 로고
    • Synthesis of pesticide-specific single-chain Fv utilizing the recombinant phage antibody system (RPAS, Pharmacia). A detailed protocol
    • (1998) Anal. Letters , vol.31 , pp. 67-92
    • Kramer, K.1
  • 30
    • 0014949207 scopus 로고
    • Cleavage of structural proteins during the assembly of the head of bacteriophage T4
    • (1970) Nature , vol.227 , pp. 680-685
    • Laemmli, U.K.1
  • 33
    • 0032783692 scopus 로고    scopus 로고
    • Isolation and characterization of an anti-CD16 single-chain Fv fragment and construction of an anti-HER2/neu/anti-CD16 bispecific scFv that triggers CD16-dependent tumor cytolysis
    • (1999) Mol. Immunol. , vol.36 , pp. 433-445
    • McCall, A.M.1    Adams, G.P.2    Amoroso, A.R.3
  • 39
    • 0345712326 scopus 로고    scopus 로고
    • High cytoplasmic expression in E. coli, purification, and in-vitro refolding of a single chain Fv antibody fragment against the hepatitis B surface antigen
    • (1999) J. Biotechnol. , vol.72 , pp. 13-20
    • Sanchez, L.1    Ayala, M.2    Freyre, F.3
  • 43
    • 0034705969 scopus 로고    scopus 로고
    • Widely used spermicide may increase, not decrease, risk of HIV transmission
    • (2000) J.A.M.A. , vol.284 , pp. 949
    • Stephenson, J.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.