Prevalence of Werner syndrome gene mutations in the Japanese population: A genetic epidemiological study

Gann Monographs on Cancer Research

Volumn 49, Issue , 2001, Pages 19-25

  Satoh, M ^a   Matsumoto, T ^a   Imai, M ^a   Sugimoto, M ^a   Tsugane, S ^a   Furuichi, Y ^a   Goto, M ^a  

^a AGENE Research Institute   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

DNA DETERMINATION; GENE MUTATION; GENETIC EPIDEMIOLOGY; GEOGRAPHIC DISTRIBUTION; HAPLOTYPE; HETEROZYGOTE DETECTION; HUMAN; JAPAN; MAJOR CLINICAL STUDY; POPULATION RESEARCH; PREVALENCE; PRIORITY JOURNAL; REVIEW; WERNER SYNDROME;

EID: 0034797703     PISSN: 00720151     EISSN: None     Source Type: Book Series    
DOI: None     Document Type: Review

References (15)

1. Analysis of helicase gene mutations in Japanese Werner's syndrome patients
2. Immunological diagnosis of Werner syndrome by down-regulated and truncated gene products
3. A deletion within the murine Werner syndrome helicase induces sensitivity to inhibitors of topoisomerase and loss of cellular proliferative capacity
4. Genetics and aging; the Werner syndrome as a segmental progeroid syndrome
5. Mutation and haplotype analyses of the Werner's syndrome gene based on its genomic structure: Genetic epidemiology in the Japanese population
6. Genetic diagnosis of Werner's syndrome, a premature aging disease, by mutant allele specific amplification (MASA) and oligomer ligation assay (OLA)
7. WRN mutations in Werner syndrome
8. An apoptosis-inducing genotoxin differentiates heterozygotic carriers for Werner helicase mutations from wild-type and homozygous mutants
9. Differential effects of cytotoxic drugs on mortal and immortalized B-lymphoblastoid cell lines from normal and Werner's syndrome patients
10. Homozygous and compound heterozygous mutations at the Werner syndrome locus
11. Werner syndrome lymphoblastoid cells are sensitive to camptothecin- induced apoptosis in S-phase
12. Cytogenetic aspects of Werner syndrome
13. Prevalence of Werner's syndrome heterozygotes in Japan
14. Abnormal telomere dynamics of B-lymphoblastoid cell strains from Werner's syndrome patients transformed by Epstein-Barr virus
15. Positional cloning of the Werner's syndrome gene