Prevalence of Werner's syndrome heterozygotes in Japan

Lancet

Volumn 353, Issue 9166, 1999, Pages 1766-

  Satoh, Misako ^b   Imai, Mitsunobu ^b   Sugimoto, Masanobu ^b   Goto, Makoto ^b   Furuichi, Yasuhiro ^a  

^a AGENE Research Institute   (Japan)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

DNA;

ARTICLE; AUTOSOMAL RECESSIVE INHERITANCE; DNA SEQUENCE; GENE MUTATION; HETEROZYGOTE; HUMAN; PREVALENCE; PRIORITY JOURNAL; WERNER SYNDROME;

EID: 0344867894     PISSN: 01406736     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0140-6736(98)05869-3     Document Type: Article

References (5)

1. Yu CE, Oshima J, Fu YH, et al. Positional cloning of the Werner's syndrome gene. Science 1996; 272: 258-62.
2. Goto M. Hierarchical deterioration of body systems in Werner's syndrome: implications for normal ageing. Mech Ageing Develop 1997; 97: 239-54.
3. Matsumoto T, Imamura O, Yamabe Y, et al. Mutation and haplotype analyses of the Werner's syndrome gene based on its genomic structure: genetic epidemiology in the Japanese population. Human Genetics 1997; 100: 123-30.
4. Matsumoto T, Tsuchihashi Z, Ito C, et al. Genetic diagnosis of Werner's syndrome, a premature aging disease, by mutant allel specific amplification (MASA) and oligomer ligation assay (OLA). J Anti-aging Med 1998; 1: 131-40.
5. Ogburn CE, Oshima J, Poot M, et al. An apoptosis-inducing genotoxin differentiates heterozygotic carriers for Werner helicase mutations from wild-type and homozygous mutants. Hum Genet 1997; 101: 121-25.