ATP-gated ion channel P2X3 is increased in human inflammatory bowel disease

Neurogastroenterology and Motility

Volumn 13, Issue 4, 2001, Pages 365-369

  Yiangou, Y ^a   Facer, P ^a   Baecker, P A ^b   Ford, A P ^b   Knowles, C H ^c   Chan, C L H ^c   Williams, N S ^c   Anand, P ^a  

^a HAMMERSMITH HOSPITAL   (United Kingdom)

^b ROCHE BIOSCIENCE   (United States)

^c QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

Author keywords

Adenosine 5 triphosphate; Immunohistochemistry; Inflammatory bowel disease; P2X3; Western blotting

Indexed keywords

ADENOSINE TRIPHOSPHATE; CATION CHANNEL; PERIPHERIN; PURINE P2X RECEPTOR; RECEPTOR SUBTYPE;

ABDOMINAL PAIN; ARTICLE; AUTONOMIC NERVOUS SYSTEM; COLON; CONTROLLED STUDY; DENDRITE; ENTERITIS; HUMAN; HUMAN TISSUE; IMMUNOCOMPETENT CELL; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; INTESTINE MOTILITY; MYENTERIC PLEXUS; NERVE CELL; NERVE FIBER; OPTICAL DENSITY; PRIORITY JOURNAL; PROTEIN LOCALIZATION; RODENT; SPECIES DIFFERENCE; WESTERN BLOTTING;

ADENOSINE TRIPHOSPHATE; BLOTTING, WESTERN; COLITIS, ULCERATIVE; COLON; CROHN DISEASE; HUMANS; IMMUNOHISTOCHEMISTRY; ION CHANNEL GATING; ION CHANNELS; RECEPTORS, PURINERGIC P2; REFERENCE VALUES;

EID: 0034796360     PISSN: 13501925     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2982.2001.00276.x     Document Type: Article

References (35)

1. ATP mediates fast synaptic transmission in mammalian neurones
2. ATP receptor-mediated synaptic currents in the central nervous system
3. Nomenclature and classification of purinoceptors
4. Nucleotide receptors
5. Receptors for purines and pyrimidines
6. Cloning of P2X5 and P2X6 receptors and the distribution and properties of an extended family of ATP-gated ion channels
7. J Neurosci
8. A P2X purinoceptor expressed by a subset of sensory neurons
9. Distinct ATP receptors on pain-sensing and stretch-sensing neurons
10. Evidence for P2X3, P2X4, P2X5 but not P2X7 containing purinergic receptors in Muller cells of the rat retina
11. Expression of purinergic receptors in bipolar cells of the rat retina
12. Coexpression of P2X2 and P2X3 receptor subunits can account for ATP-gated currents in sensory neurons
13. State-dependant cross-inhibition between transmitter-gated cation channels
14. One-way cross-desensitization between P2X purinoceptors and vanilloid receptors in adult rat dorsal root ganglion neurones
15. P2X receptor immunoreactivity in the male genital organs of the rat
16. Intraepithelial vagal sensory nerve terminals in rat pulmonary neuroepithelial bodies express P2X3 receptors
17. Distribution of P2X receptors in the urinary bladder and the ureter of the rat
18. Distribution of purinergic P2X receptors in the rat heart
19. Distribution of P2X receptors in the rat adrenal gland
20. Characterization and chromosomal localization of a human P2X receptor from the urinary bladder
21. Mol Pharmacol
22. Molecular characterization and pharmacological properties of the human P2X3 purinoceptor
23. P2X3 receptor in injured human sensory neurons
24. Immunocytochemical localization of P2X3 purinoceptors in sensory neurons in naïve rats following neuropathic injury
25. The glucose oxidase-DAB-nickel method in peroxidase histochemistry of the nervous system
26. The expression of P2X3 purinoreceptors in sensory neurons: Effects of axotomy and glial-derived neurotrophic factor
27. Increased capsaicin receptor VR1-immunoreactivity in inflamed human bowel
28. Increased acid-sensing ion channel ASIC-3 in inflamed human intestine
29. Connections between P2 purinoceptors and capsaicin-sensitive afferents in the intestine and other tissues
30. Ectopic purinergic sensitivity develops at sites of chronic nerve constriction injury in rat
31. Purinergic sensory neurotransmission in urinary bladder: An in vitro study in the rat
32. Ion channels of nociception
33. P2X3 is expressed by DRG neurons that terminate in inner lamina II
34. GDNF and its receptor component Ret in injured human nerves and dorsal root ganglia
35. Glial-derived neurotrophic factor in human adult and fetal intestine and in Hirschsprung's disease