Plague vaccine research and development

Journal of Applied Microbiology

Volumn 91, Issue 4, 2001, Pages 606-608

  Williamson, E D ^a  

^a DEFENCE SCIENCE AND TECHNOLOGY LABORATORY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODIES; MAMMALS;

GENE DELETION; INTERLEUKIN-4; PLAGUE VACCINES; PROTECTIVE EFFECTS; SMALL ANIMAL MODEL; SUBUNIT VACCINE; VACCINE RESEARCH AND DEVELOPMENT;

VACCINES;

PLAGUE VACCINE; RECOMBINANT ANTIGEN; RECOMBINANT F1 ANTIGEN; RECOMBINANT V ANTIGEN; RECOMBINANT VACCINE; UNCLASSIFIED DRUG; VIRULENCE FACTOR;

PLAGUE; VACCINATION;

ANIMAL MODEL; ANTIBODY RESPONSE; ANTIBODY TITER; CONFERENCE PAPER; DISEASE MARKER; DRUG EFFICACY; DRUG MECHANISM; DRUG SCREENING; EPIDEMIC; IMMUNOGENICITY; INFECTION PREVENTION; NONHUMAN; PLAGUE; VACCINE PRODUCTION; YERSINIA PESTIS;

EID: 0034795760     PISSN: 13645072     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2672.2001.01497.x     Document Type: Conference Paper

References (14)

1. Expression of a recombinant form of the V antigen of Yersinia pestis, using three different expression systems
2. The F1 and V subunit vaccine protects against plague in the absence of IL-4 driven immune responses
3. The SCID/Beige mouse as a model to investigate protection against Yersinia pestis
4. Protection conferred by a fully recombinant subunit vaccine against Yersinia pestis in male and female mice of four inbred strains
5. Effectiveness of live or killed plague vaccines in man
6. Plague immunisation. I. Past and present trends
7. Live attenuated Yersinia pestis vaccine: Virulent in non-human primates, harmless to guinea pigs
8. Macromolecular organization of recombinant Yersinia pestis F1 antigen and the effect of structure on immunogenicity
9. Yersinia pestis - Etiologic agent of plague
10. The V-antigen of Yersinia is surface exposed before target cell contact and involved in virulence protein translocation
11. Expression of the Yersinia pestis capsular antigen (F1 antigen) on the surface of an aro A mutant of Salmonella typhimurium induces high level protection against plague
12. A subunit vaccine elicits IgG in serum, spleen cell cultures and bronchial washings and protects immunized animals against pneumonic plague
13. An IgG1 titre to the F1 and V antigens correlates with protection against plague in the mouse model
14. A single dose subunit vaccine protects against pneumonic plague