Expression of a recombinant form of the V antigen of Yersinia pestis, using three different expression systems

Vaccine

Volumn 18, Issue 1-2, 1999, Pages 153-159

  Carr, S ^a   Miller, J ^a   Leary, S E C ^a   Bennett, A M ^a   Ho, A ^a   Williamson, E D ^a  

^a DEFENCE SCIENCE AND TECHNOLOGY LABORATORY   (United Kingdom)

Author keywords

Sub unit vaccine; V antigen; Yersinia pestis

Indexed keywords

PLAGUE VACCINE;

ANTIGEN EXPRESSION; ANTIGEN PURIFICATION; ARTICLE; BACTERIAL VIRULENCE; IMMUNOGENICITY; PLAGUE; PRIORITY JOURNAL; VACCINE PRODUCTION; YERSINIA PESTIS;

AMINO ACID SEQUENCE; ANIMALS; ANTIGENS, BACTERIAL; CLONING, MOLECULAR; IMMUNIZATION; MICE; MICE, INBRED BALB C; MOLECULAR SEQUENCE DATA; PORE FORMING CYTOTOXIC PROTEINS; RECOMBINANT PROTEINS; YERSINIA PESTIS;

EID: 0033588521     PISSN: 0264410X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0264-410X(99)00214-5     Document Type: Article

References (8)

1. Williamson E.D., Eley S.M., Stagg A.J., Green M., Russell P., Titball R.W. A sub-unit vaccine elicits IgG in serum, spleen cell cultures and in bronchial washings and protects immunised animals against pneumonic plague. Vaccine. 15:1997;1079-1084.
2. Meyer K.F. Effectiveness of live or killed plague vaccines in man. Bull. WHO. 4:1970;653-666.
3. Marshall J.D. Jr, Bartelloni P.J., Cavanaugh D.C., Kadull P.J., Meyer K.F. Plague immunisation, II. Relation of adverse clinical reactions to multiple immunisations with killed vaccine. J. Infect. Dis. 129:1974;S19-S25.
4. Williamson E.D., Eley S.M., Griffin K.F., Green M., Russell P., Leary S.E.C., Oyston P.C.F., Easterbrook T., Reddin K.M. A new improved sub-unit vaccine for plague: the basis of protection. FEMS Immun. Med. Micro. 12:1995;223-230.
5. Leary S.E.C., Williamson E.D., Griffin K.F., Russell P., Eley S.M., Titball R.W. Active immunisation with recombinant V antigen from Yersinia pestis protects mice against plague. Infect. Immun. 63:1995;2854-2858.
6. Titball R.W., Howells A.M., Oyston P.C.F., Williamson E.D. Expression of the Y. pestis capsular F1 antigen on the surface of an aroA mutant of Salmonella typhimurium induces high levels of protection against plague. Infect. Immun. 65:1997;1926-1930.
7. Price S.B., Leung K.Y., Barve S.S., Straley S.C. Molecular analysis of lcrGVH, the V antigen operon of Yersinia pestis. J. Bacteriol. 171:1989;5633-5646.
8. Smith P.K., Krohn R.I., Hermanson G.T., Mallia A.K., Gartner F.H., Provenzano M.D., Fujimoto E.K., Goeke N.M., Olson B.J. Measurement of protein using bicinchoninic acid. Anal. Biochem. 150:1985;76-85.