Altered interaction of cis-dichlorodiammineplatinum(II)-modified α2-macroglobulin (α2M) with the low density lipoprotein receptor-related protein/ α2M receptor but not the α2M signaling receptor. Evidence for interference with receptor dissociation and recycling

Journal of Clinical Investigation

Volumn 97, Issue 5, 1996, Pages 1193-1203

  Howard, Gayle Charlyne ^a   Misra, Uma Kant ^a   DeCamp, Dianne Lynn ^a   Pizzo, Salvatore Vincent ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Cisplatin; Endocytosis; Macrophage; Proteinase inhibitors; Signaling

Indexed keywords

ALPHA 2 MACROGLOBULIN; CISPLATIN; GUANINE NUCLEOTIDE BINDING PROTEIN; LOW DENSITY LIPOPROTEIN RECEPTOR; PROTEINASE INHIBITOR; RECEPTOR PROTEIN;

ANIMAL CELL; ANTIGEN PRESENTATION; ARTICLE; CONTROLLED STUDY; ENDOCYTOSIS; ENDOSOME; INTERNALIZATION; MACROPHAGE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN MODIFICATION; PROTEIN PROTEIN INTERACTION; PROTEINASE INHIBITION; SIGNAL TRANSDUCTION;

ALPHA-MACROGLOBULINS; AMINO ACID SEQUENCE; ANIMALS; ANTINEOPLASTIC AGENTS; BASE SEQUENCE; CALCIUM; CISPLATIN; ENDOCYTOSIS; HUMANS; HYDROGEN-ION CONCENTRATION; LDL-RECEPTOR RELATED PROTEIN 1; MICE; MICE, INBRED C57BL; MOLECULAR SEQUENCE DATA; RECEPTORS, IMMUNOLOGIC;

EID: 0029919576     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI118533     Document Type: Article

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