Modeling genetic networks and their evolution: A complex dynamical systems perspective

Biological Chemistry

Volumn 382, Issue 9, 2001, Pages 1289-1299

  Bornholdt, S ^a  

^a UNIVERSITY OF KIEL   (Germany)

Author keywords

Complex systems; Evolutionary genomics; Functional genomics; Genetic networks; Genome wide modeling; Self organization; Simulation studies

Indexed keywords

BIOMEDICINE; COMPUTER SIMULATION; CONTROLLED STUDY; EXPERIMENTATION; GENE EXPRESSION; GENE FUNCTION; GENE SEQUENCE; GENE SWITCHING; GENETIC CONSERVATION; GENETIC MODEL; GENETIC ORGANIZATION; GENETIC REGULATION; MEDICAL GENETICS; MOLECULAR DYNAMICS; PRIORITY JOURNAL; REVIEW; TRANSCRIPTION REGULATION;

EVOLUTION; GENOME; MODELS, GENETIC;

EID: 0034780804     PISSN: 14316730     EISSN: None     Source Type: Journal    
DOI: 10.1515/BC.2001.161     Document Type: Review

References (62)

1. Robustness in bacterial chemotaxis
2. Punctuated equilibrium and criticality in a simple model of evolution
3. Self-organized criticality: An explanation of the 1/f noise
4. Closing probabilities in the Kauffman model: An annealed computation
5. Relevant elements magnetization, and dynamical properties in Kauffman networks: A numerical study
6. Emergent properties of networks of biological signaling pathways
7. Data analysis and integration: Of steps and arrows
8. Neutral mutations and punctuated equilibrium in evolving genetic networks
9. Robustness as an evolutionary principle
10. A genome-wide transcriptional analysis of the mitotic cell cycle
11. Evolution of random networks
12. Genetic network inference: From Co-expression clustering to reverse engineering
13. Exploring the metabolic and genetic control on a genomic scale
14. Dynamical phase transition in non-symmetrical spin glasses
15. Random networks of automata: A simple annealed approximation
16. On the origin of species by sympatric speciation
17. Test of synergistic interactions among deleterious mutations in bacteria
18. On the evolution of random graphs
19. Analysis of expressed sequence tags indicates 35000 human genes
20. Punctuated equilibrium comes of age
21. Theoretical Biology: A robust view of biochemical pathways
22. Dissecting the regulatory circuitry of a eukaryotic genome
23. Correspondence between neural threshold networks and Kauffman Boolean cellular automata
24. Critical phenomena in model neural networks
25. Isologous diversification for robust development of cell society
26. Metabolic stability and epigenesis in randomly constructed genetic nets
27. Requirements for evolvability in complex systems: Orderly dynamics and frozen components
28. The Origins of Order: Self-Organization and Selection in Evolution
29. The Neutral Theory of Molecular Evolution
30. Expected time for random genetic drift of a population between stable phenotypic states
31. Global analysis of the genetic network controlling a bacterial cell cycle
32. Robustness of a gene regulatory circuit
33. Neo-darwinian evolution implies punctuated equilibrium
34. Power spectra of extinction in the fossil record
35. Synexpression groups in eukaryotes
36. Self-organized networks of competing Boolean agents
37. Genomic evolution during a 10,000-generation experiment with bacteria
38. Beyond the Hox complex
39. Developing a new view on evolution
40. Genome-wide location and function of DNA Binding proteins
41. Parameter sensitivity as a criterion for evaluating and comparing the performance of biochemical systems
42. Landscapes and molecular evolution
43. Genome system architecture and natural genetic engineering in evolution
44. On Macroevolution, extinctions and critical phenomena
45. Extinction and self-organized critically in a model of large-scale evolution
46. Self-similarity of extinction statistics in the fossil record
47. Modelling the complexity of genetic networks: Understanding multigenic and pleiotropic regulation
48. Introcuction to Percolation Theory
49. Exploring complex networks
50. Systematic determination of genetic network architecture
51. The Chipping Forecast
52. From specific gene regulation to global regulatory networks: A characterization of Escherichia coli transcriptional network
53. A new evolutionary law
54. Does evolutionary plasticity evolve?
55. Decoupled evolution of coding region and mRNA expression patterns after gene duplication: Implications for the neutralist-selectionist debate
56. Robustness against mutations in genetic networks of yeast
57. Large-scale temporal gene expression mapping of central nervous system development
58. Microarray analysis of Drosophila development during metamorphosis
59. Character change, speciation, and the higher taxa