Regulation of cloned ATP-sensitive K channels by adenine nucleotides and sulfonylureas: Interactions between SUR1 and positively charged domains on Kir6.2

Journal of General Physiology

Volumn 118, Issue 4, 2001, Pages 391-405

  John, Scott A ^a   Weiss, James N ^a   Ribalet, Bernard ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Adenine nucleotides; Inward rectifier K channel; Nucleotide binding fold; PIP2; SUR

Indexed keywords

ADENINE NUCLEOTIDE; ADENOSINE TRIPHOSPHATE; GLIBENCLAMIDE; MEMBRANE PROTEIN; POTASSIUM CHANNEL; PROTEIN KIR6.X; SULFONYLUREA; SULFONYLUREA RECEPTOR 1; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ARTICLE; BINDING SITE; CHANNEL GATING; CONTROLLED STUDY; HUMAN; HUMAN CELL; MOLECULAR INTERACTION; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION;

ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATE; ARGININE; ATP-BINDING CASSETTE TRANSPORTERS; CELL LINE; CELL MEMBRANE; CLONING, MOLECULAR; CYSTEINE; DOSE-RESPONSE RELATIONSHIP, DRUG; GREEN FLUORESCENT PROTEINS; HUMANS; LUMINESCENT PROTEINS; PATCH-CLAMP TECHNIQUES; PHOSPHATIDYLINOSITOL 4,5-DIPHOSPHATE; POTASSIUM CHANNELS; POTASSIUM CHANNELS, INWARDLY RECTIFYING; RECEPTORS, DRUG; SULFONYLUREA COMPOUNDS; TRANSFECTION;

EID: 0034779998     PISSN: 00221295     EISSN: None     Source Type: Journal    
DOI: 10.1085/jgp.118.4.391     Document Type: Article

References (24)

1. Adenosine 5′-triphosphate-sensitive potassium channels
2. 2 and PIP as determinants for ATP inhibition of KATP channels
3. ATP channel complex
4. ATP channel inhibition by ATP requires distinct functional domains of the cytoplasmic C terminus of the pore-forming subunit
5. ATP channel gating: Toward a unified molecular understanding
6. Anionic phospholipids activate ATP-sensitive potassium channels
7. + channel. A molecular probe for the mechanism of ATP-sensitive inhibition
8. + channel in rat ventricular myocytes
9. The molecular analysis of ATP-sensitive potassium channels. Determinants on the pore subunit
10. Transformation of rat cells by DNA of human adenovirus 5
11. The essential role of Walker A motifs of SUR1 in K-ATP channel activation by Mg-ADP and diazoxide
12. The sulfonylurea receptor SUR1 regulates ATP-sensitive mouse Kir6.2 K channels linked to the green fluorescent protein in human embryonic kidney cells (HEK 293)
13. ATP channels: Functional coupling of Kir6.2 and SUR1 subunits
14. Adenosine diphosphate as an intracellular regulator of insulin secretion
15. 2): A study of channel rundown and reactivation
16. Involvement of the N-terminus of Kir6.2 in coupling to the sulfonylurea receptor
17. + channel with an ABC transporter
18. The C terminus of SUR1 is required for trafficking of KATP channels
19. ATP channels
20. ATP channels
21. + channels toward intracellular nucleotide diphosphates
22. Molecular analysis of ATP-sensitive K channel gating and implications for channel inhibition by ATP
23. Truncation of Kir6.2 produces ATP-sensitive K channels in the absence of the sulfonylurea receptor
24. Cooperative binding of ATP and MgADP in the sulfonylurea receptor is modulated by glibenclamide