Hyaluronan-independent adhesion of CD44H+ and CD44v10+ lymphocytes to dermal microvascular endothelial cells and keratinocytes

Journal of Investigative Dermatology

Volumn 117, Issue 4, 2001, Pages 949-957

  Weimann, Tatjana K ^a   Wagner, Christine ^a   Funk, Renate ^a   Hirche, Herbert ^a   Goos, Manfred ^a   Wagner, Stephan N ^a  

^a UNIVERSITY OF DUISBURG ESSEN   (Germany)

Author keywords

Heterotypic adhesion; Homotypic adhesion; Transfection; UVA

Indexed keywords

CYTOKINE; HERMES ANTIGEN; HYALURONIC ACID; INTEGRIN; SELECTIN;

ARTICLE; ASSAY; BINDING AFFINITY; CELL ADHESION; CONTROLLED STUDY; DELAYED HYPERSENSITIVITY; DERMIS; ENDOTHELIUM CELL; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; INFLAMMATION; KERATINOCYTE; KINETICS; LYMPHOCYTE; LYMPHOCYTIC INFILTRATION; MICROVASCULATURE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SKIN INFLAMMATION; ULTRAVIOLET A RADIATION;

EID: 0034773297     PISSN: 0022202X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.0022-202X.2001.01467.x     Document Type: Article

References (50)

1. CD44 is the principal cell surface receptor for hyaluronate
2. In vivo induction of insulin-like growth factor-I receptor and CD44v6 confers homing and adhesion to murine multiple myeloma cells
3. Interaction between CD44 and hyaluronate is directly implicated in the regulation of tumor development
4. Regulation of growth and dissemination of a human lymphoma by CD44 splice variants
5. Glycosylation of CD44 is implicated in CD44-mediated cell adhesion to hyaluronan
6. Regulation of CD44 binding to hyaluronan by glycosylation of variably spliced exons
7. Phenotypic characterization of CD4+ T cells that exhibit a transendothelial migratory capacity
8. Antibodies to CD44 and integrin alpha4, but not L-selectin, prevent central nervous system inflammation and experimental encephalomyelitis by blocking secondary leukocyte recruitment
9. Human keratinocytes express a new CD44 core protein (CD44E) as a heparan-sulfate intrinsic membrane proteoglycan with additional exons
10. CD44 antibody stimulates adhesion of peripheral blood T cells to keratinocytes through the leukocyte function-associated antigen-1/intercellular adhesion molecule-1 pathway
11. Leukocyte-endothelial cell recognition: Three (or more) steps to specificity and diversity
12. CD44 is necessary for optimal contact allergic responses but is not required for normal leukocyte extravasation
13. CD44 and its ligand hyaluronate mediate rolling under physiologic flow: A novel lymphocyte-endothelial cell primary adhesion pathway
14. Requirement for CD44 in activated T cell extravasation into an inflammatory site
15. CD44 activation and associated primary adhesion is inducible via T cell receptor stimulation
16. Expression of human CD44R1 enhances the metastatic capacity of murine fibrosarcoma cells
17. Functional activation of lymphocyte CD44 in peripheral blood is a marker of autoimmune disease activity
18. A new variant of glycoprotein CD44 confers metastatic potential to rat carcinoma cells
19. The peripheral lymph node homing receptor, LECAM-1, is involved in CD18-independent adhesion of human neutrophils to endothelium
20. Ultraviolet-A radiation induces adhesion molecule expression on human dermal microvascular endothelial cells
21. Proteoglycan forms of the lymphocyte homing receptor CD44 are alternatively spliced variants containing the v3 exon
22. Lymphocyte CD44 binds the COOH-terminal heparin-binding domain of fibronectin
23. CD44 variants but not CD44s cooperate with beta1-containing integrins to permit cells to bind to osteopontin independently of arginine-glycine-aspartic acid, thereby stimulating cell motility and chemotaxis
24. Immunomodulatory functions of low-molecular weight hyaluronate in an acute rat renal allograft rejection model
25. Immunomodulatory functions of hyaluronate in the LEW-to-F 344 model of chronic cardiac allograft rejection
26. Triggering of the CD44 antigen on T lymphocytes promotes T cell adhesion through the LFA- 1 pathway
27. CD44 and its interaction with extracellular matrix
28. The cell adhesion molecule, GP116, is a new CD44 variant (ex14/v10) involved in hyaluronic acid binding and endothelial cell proliferation
29. Anti-CD44 treatment abrogates tissue oedema and leukocyte infiltration in murine arthritis
30. Hyaluronate can function as a cell adhesion molecule and CD44 participates in hyaluronate recognition
31. Interleukin 1 and tumor necrosis factor stimulate human vascular endothelial cells to promote transendothelial neutrophil passage
32. Hyaluronan anchoring and regulation on the surface of vascular endothelial cells is mediated through the functionally active form of CD44
33. The two major CD44 proteins expressed on a metastatic rat tumor cell line are derived from different splice variants: Each one individually suffices to confer metastatic behavior
34. Tumor endothelium selectively supports binding of IL-2-propagated tumor-infiltrating lymphocytes
35. Genomic structure of DNA encoding the lymphocyte homing receptor CD44 reveals at least 12 alternatively spliced exons
36. The CD44-initiated pathway of T-cell extravasation uses VLA-4 but not LFA-1 for firm adhesion
37. Regulated clustering of variant CD44 proteins increases their hyaluronate binding capacity
38. Traffic signals for lymphocyte recirculation and leukocyte emigration: The multistep paradigm
39. The hematopoietic and epithelial forms of CD44 are distinct polypeptides with different adhesion potentials for hyaluronate-bearing cells
40. Lymphocyte homing into lymph nodes: In vitro demonstration of the selective affinity of recirculating lymphocytes for high-endothelial venules
41. Distinct effects of two CD44 isoforms on tumor growth in vivo
42. Function of lymphocyte homing-associated adhesion molecules on human natural killer and lymphokine-activated killer cells
43. Administration of antibodies to hyaluronan receptor (CD44) delays the start and ameliorates the severity of collagen II arthritis
44. Hyaluronan-independent lodgement of CD44+ lymphoma cells in lymphoid organs
45. Predominant expression of CD44 splice variant v10 in malignant and reactive human skin lymphocytes
46. Expression of adhesion molecules and their ligands in contact allergy
47. Abrogation of experimental colitis correlates with increased apoptosis in mice deficient for CD44 variant exon 7 (CD44v7)
48. A directly spliced exon 10-containing CD44 variant promotes the metastasis and homotypic aggregation ofaggressive non-Hodgkin's lymphoma
49. Hyaluronan on the surface of tumor cells is correlated with metastatic behavior