Endothelin-1 gene suppression by shear stress: Pharmacological evaluation of the role of tyrosine kinase, intracellular calcium, cytoskeleton, and mechanosensitive channels

Journal of Molecular and Cellular Cardiology

Volumn 31, Issue 2, 1999, Pages 387-399

  Malek, Adel M ^a,d   Zhang, Janet ^b   Jiang, Jianwei ^c   Alper, Seth L ^c   Izumo, Seigo ^b  

^a BOSTON CHILDREN S HOSPITAL   (United States)

^b BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

^c HARVARD MEDICAL SCHOOL   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Atherosclerosis; Flow; Gene regulation; Mechanosensitive channels; Mechanotransduction; Membrane depolarization; Microtubules; Nitric oxide; Nocodazole; Phalloidin; Rheology; Taxol; Tyrosine kinase; Vascular disease

Indexed keywords

CALCIUM; CATION CHANNEL; CYTOCHALASIN D; ENDOTHELIN 1; F ACTIN; GADOLINIUM; HERBIMYCIN A; MESSENGER RNA; PHALLOIDIN; POTASSIUM; PROTEIN TYROSINE KINASE; TETRYLAMMONIUM;

ANIMAL CELL; ARTICLE; CALCIUM CELL LEVEL; CYTOSKELETON; GENE REPRESSION; MECHANORECEPTOR; MEMBRANE DEPOLARIZATION; MICROFILAMENT; NONHUMAN; PRIORITY JOURNAL; RNA TRANSLATION; SHEAR STRESS; SIGNAL TRANSDUCTION;

EID: 0033083473     PISSN: 00222828     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmcc.1998.0873     Document Type: Article

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