Molecular determinants of peptide binding to two common rhesus macaque major histocompatibility complex class II molecules

Journal of Virology

Volumn 75, Issue 22, 2001, Pages 10958-10968

  Dzuris, J L ^a   Sidney, J ^a   Horton, H ^a   Correa, R ^a   Carter, D ^a   Chesnut, R W ^a   Watkins, D I ^a   Sette, A ^a  

^a Epimmune   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EPITOPE; GAMMA INTERFERON; HLA DR ANTIGEN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; REV PROTEIN;

ALLELE; AMINO ACID SUBSTITUTION; ANIMAL CELL; ANTIGEN BINDING; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; FLOW CYTOMETRY; HYDROPHOBICITY; MACACA; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; RHESUS MONKEY; SIMIAN IMMUNODEFICIENCY VIRUS; VIRUS GENOME;

AMINO ACID SEQUENCE; ANIMALS; EPITOPES; HIV; HLA-DR ANTIGENS; MACACA MULATTA; MOLECULAR SEQUENCE DATA; PEPTIDE FRAGMENTS; SIMIAN IMMUNODEFICIENCY VIRUS; VIRAL ENVELOPE PROTEINS;

EID: 0034767233     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.75.22.10958-10968.2001     Document Type: Article

References (56)

1. Development of high potency universal DR-restricted helper epitopes by modification of high affinity DR-blocking peptides
2. SIV and SHIV CTL epitopes identified in macaques
3. + lymphocytes from simian immunodeficiency virus-infected rhesus macaques recognize 14 different epitopes bound by the major histocompatibility complex class I molecule Mamu-A*01: Implications for vaccine design and testing
4. Robust Tatspecific CD8 responses select for escape variants during the acute phase of infection with cloned SIV
5. Characterization of the peptide binding motif of a rhesus MHC class I molecule (Mamu-A*01) that binds an immunodominant CTL epitope from simian immunodeficiency virus
6. Phenotypic analysis of antigen-specific T lymphocytes
7. Human class I supertypes and CTL repertoires extend to chimpanzees
8. Kidney transplantation in rhesus monkeys. Matching for D/DR antigens, pretransplant blood transfusions, and immunological monitoring before transplantation
9. The MHC class I genes of the rhesus monkey. Different evolutionary histories of MHC class I and class II genes in primates
10. Degenerate binding of immunogenic peptides to HLA-DR proteins on B cell surfaces
11. Mutant human B cell lines deficient in class II major histocompatibility complex transcription
12. + T-cell epitope within nonstructural protein 3 in acute hepatitis C virus infection
13. Unprecedented polymorphism of MHC-DRB region configurations in rhesus macaques
14. Conserved MHC class I peptide binding motif between humans and rhesus macaques
15. + cytotoxic T lymphocytes specific for dominant and nondominant viral epitopes in simianhuman immunodeficiency virus-infected rhesus monkeys
16. Virus-specific cytotoxic T-lymphocyte responses select for amino-acid variation in simian immunodeficiency virus Env and Nef
17. Definition of five new simian immunodeficiency virus cytotoxic T-lymphocyte epitopes and their restricting major histocompatibility complex class I molecules: Evidence for an influence on disease progression
18. Protein pool sequencing of natural HLA-DR, DQ, and DP ligands reveals detailed peptide motifs, constraints of processing, and general rules
19. A nonhuman primate model for human cerebral malaria: Rhesus monkeys experimentally infected with Plasmodium fragile
20. The simian immunodeficiency virus envelope glycoprotein contains two epitopes presented by the Mamu-A*01 class I molecule
21. Evolutionary conservation of major histocompatibility complex-DR/peptide/T cell interactions in primates
22. Purification and characterization of class II histocompatibility antigens from a homozygous human B cell line
23. 131-Ilabelled human growth hormone of high specific radioactivity
24. Promiscuous and allele-specific anchors in HLA-DR-binding peptides
25. Effective induction of simian immunodeficiency virus-specific cytotoxic T lymphocytes in macaques by using a multiepitope gene and DNA prime-modified vaccinia virus Ankara boost vaccination regimen
26. Exploration of requirements for peptide binding to HLA DRB1*0101 and DRB1*0401
27. Towards an HIV-1 vaccine: Lessons from studies in macaque models
28. Treatment with humanized monoclonal antibody against CD154 prevents acute renal allograft rejection in nonhuman primates
29. A high frequency of Mamu-A*01 in the rhesus macaque detected by polymerase chain reaction with sequence-specific primers and direct sequencing
30. Identification of new Mamu-DRB alleles using DGGE and direct sequencing
31. Single amino acid changes in DR and antigen define residues critical for peptide-MHC binding and T cell recognition
32. + T lymphocytes in simian/human immunodeficiency virus-infected and vaccinated rhesus monkeys detected using a peptide-major histocompatibility complex class II tetramer
33. Analysis of Gag-specific cytotoxic T lymphocytes in simian immunodeficiency virus-infected rhesus monkeys by cell staining with a tetrameric major histocompatibility complex class I-peptide complex
34. + memory T cells
35. + T helper cells from simian/human immunodeficiency virus-infected rhesus monkeys recognize epitopes restricted by MHC class II DRBI*0406 and DRB*w201 molecules
36. Identification of DRB alleles in rhesus monkeys using polymerase chain reaction-sequence-specific primers (PCR-SSP) amplification
37. Activation of a myelin basic proteinspecific human T cell clone by antigen-presenting cells from rhesus monkeys
38. Use of the rhesus monkey as an experimental model to test the degree of efficacy of an antisporozoite peptide malarial vaccine candidate combined with copolymerbased adjuvants
39. Prevention of renal allograft rejection in primates by blocking the B7/CD28 pathway
40. On the interaction of promiscuous antigenic peptides with different DR alleles
41. Characterization of the specificity of peptide binding to four DR haplotypes
42. Allelic diversity of MHC-DRB alleles in rhesus macaques
43. Universally immunogenic T cell epitopes: Promiscuous binding to human MHC class II and promiscuous recognition by T cells
44. + T cells are detectable in most individuals with active HIV-1 infection, but decline with prolonged viral suppression
45. The SIV-infected rhesus monkey model for HIV-associated dementia and implications for neurological diseases
46. A sequence pattern common to T cell epitopes
47. Prominent role of secondary anchor residues in peptide binding to HLA-A2.1 molecules
48. Recombinant modified vaccinia virus Ankara-simian immunodeficiency virus gag pol elicits cytotoxic T lymphocytes in rhesus monkeys detected by a major histocompatibility complex class I/peptide tetramer
49. Structural analysis of peptides capable of binding to more than one Ia antigen
50. Definition of the Mamu-A*01 peptide binding specificity: Application to the identification of wild-type and optimized ligands from simian immunodeficiency virus regulatory proteins
51. A malaria T-cell epitope recognized in association with most mouse and human MHC class II molecules
52. Gel electrophoretic analysis of rhesus macaque major histocompatibility complex class II DR molecules
53. Several common HLA-DR types share largely overlapping peptide binding repertoires
54. Durable donor-specific T and B cell tolerance in rhesus macaques induced with peritransplantation anti-CD3 immunotoxin and deoxyspergualin: Absence of chronic allograft nephropathy
55. High affinity for class II molecules as a necessary but not sufficient characteristic of encephalitogenic determinants
56. An integrin polymorphism that defines reactivity with alloantibodies generates an anchor for MHC class II peptide binding: A model for unidirectional alloimmune responses