Neuroprotective effect of N-methyl-D-aspartate receptor antagonists in an experimental glaucoma model in the rat

Journal of Japanese Ophthalmological Society

Volumn 104, Issue 1, 2000, Pages 11-16

  Gu, Zhaobin ^a   Yamamoto, Tetsuya ^a   Kawase, Chizuru ^a   Matsubara, Masayuki ^a   Kawase, Kazuhide ^a   Sawada, Akira ^a   Kitazawa, Yoshiaki ^a  

^a GIFU UNIVERSITY   (Japan)

Author keywords

Dizocilpine; Experimental glaucoma in the rat; Memantine; Neuroprotection; Open channel blocker of NMDA receptor

Indexed keywords

AMINO ACID RECEPTOR BLOCKING AGENT; DIZOCILPINE MALEATE; MEMANTINE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR;

ANIMAL; ARTICLE; DISEASE MODEL; DRUG ANTAGONISM; GLAUCOMA; MALE; RAT; WISTAR RAT;

ANIMALS; DISEASE MODELS, ANIMAL; DIZOCILPINE MALEATE; EXCITATORY AMINO ACID ANTAGONISTS; GLAUCOMA; MALE; MEMANTINE; RATS; RATS, WISTAR; RECEPTORS, N-METHYL-D-ASPARTATE;

EID: 0033630495     PISSN: 00290203     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (35)

1. Buchan AM : Do NMDA antagonists protect against cerebral ischemia : Are clinical trials warranted? Cerebrovas Brain Metab Rev 2 : 1-26, 1990.
2. Sheardown MJ, Nielsen EO, Hansen AJ, Jacobsen P, Honore T : 2, 3-dihydroxy-6-nitro-7-suIfamoyl-benzo(F)quinoxaline : A neuroprotectant for cerebral ischemia. Science 247 : 571-574, 1990.
3. Sucher NJ, Aizenman E, Lipton SA :N-methyl-D -aspartate antagonists prevent kainate neurotoxicity in rat retinal ganglion cells in vitro. J Neurosci 11 : 966-971, 1991.
4. Siliprandi R, Canclla R, Carmignoto G, Schiavo N, Zanellato A, Zanoni R, et al: N-methyl-D-aspartate-induced neurotoxicity in the adult rat retina. Vis Neurosci 8 : 567-573, 1992.
5. Schumcr RA, Podos SM : The nerve of glaucoma. Arch Ophthalmol 112 : 37-44, 1994.
6. Yoles E, Schwartz M : Elevation of intraocular glutamate levels in rats with partial lesion of the optic nerve. Arch Ophthalmol 116 : 906-910, 1998.
7. Dreyer EB, Zurakowski D, Schumcr RA, Podos SM, Lipton SA : Elevated glutamate levels in the vitreous body of humans and monkeys with glaucoma. Arch Ophthalmol 114 : 299-305, 1996.
8. Brooks DE, Garcia GA, Dreyer EB, Zurakowski D, Franco - Bourland RE : Vitreous body glutamate concentration in dogs with glaucoma. Am J Vet Res 58 : 864-867, 1997.
9. Balazs R, Hack N, Jorgensen OS : Interactive effects involving different classes of excitatory amino acid receptors and the survival of cerebellar granule cells in culture. Int J Devl Neurosci 8 : 347-359, 1990.
10. Levy DI, Lipton SA : Comparison of delayed administration of competitive and uncompetitive antagonists in preventing NMDA receptor-mediated neuronal death. Neurology 40 : 852-855, 1990.
11. Michaels RL, Rothman SM : Glutamate neurotoxicity in vitro : Antagonist pharmacology and intracellular calcium concentrations. J Neurosci 10 : 283-292, 1990.
12. Martinez-Arizala A, Rigamonti DD, Long JB, Kraimer JM, Holaday JW : Effects of NMDA receptor antagonists following spinal ischemia in the rabbit. Exp Neurol 108 : 232-240, 1990.
13. Klockgether T, Turski L : Excitatory amino acids and the basal ganglia : Implications for the therapy of Parkinson's disease. Trends Neurosci 12 :285-286, 1989.
14. Carlsson M, Carlsson A : Interactions between glutamatergic and monoaminergic systems within the basal ganglia - implications for schizophrenia and Parkinson's disease. Trends Neurosci 13 : 272-276, 1990.
15. Schmidt WJ, Bubser M, Hauber W : Excitatory amino acids and Parkinson's disease. Trends in Neurosci 13:46. 1990.
16. Greenamyre JT : Glutamate - dopamine interactions in the basal ganglia : Relationship to Parkin-son's disease. J Neural Transm [Gen Sect] 91 : 255-269, 1993.
17. Gill R, Foster AC, Woodruff GN:MK-801 is neuroprotective in gerbils when administered during the post-ischaemic period. Neuroscience 25 : 847-855, 1988.
18. Ueda J, Sawaguchi S, Hanyu T, Yaoeda K, Fukuchi T, Abe H, et al : Experimental glaucoma model in the rat induced by laser trabecular photocoagulation after an intracameral injection of india ink. Jpn J Ophthalmol 42 : 337-344, 1998.
19. Paxinos G, Watson C : The Rat Brain in Stereotaxic Coordinates, 2 nd ed. Academic Press, San Diego, 1986.
20. Moore CG, Milne ST, Morrison JC : Noninvasive measurement of rat intraocular pressure with the tono-pen. Invest Ophthalmol Vis Sci 34 : 363-369, 1993.
21. Wheeler NC, Lee DA, Cheng Q, Ross WF, Hadjiaghai L : Reproducibility of intraocular pressure and outflow facility measured by pneumatic tonography and Schiotz tonography. J Ocul Pharmacol Ther 14 : 5-13, 1998.
22. Shareef SR, Garcia-Valenzuela E, Salierno A, Walsh J, Sharma SC : Chronic ocular hypertension following episcleral venous occlusion in rats. Exp Eye Res 61 : 379-382, 1995.
23. Laquis S, Chaudhary P, Sharma SC : The patterns of retinal ganglion cell death in hypertensive eyes. Brain Res 784 : 100-104, 1998.
24. Garcia-Valenzuela E, Shareef S, Walsh J, Sharma SC : Programmed cell death of retinal ganglion cells during experimental glaucoma. Exp Eye Res 61 : 33-44, 1995.
25. Morrison JC, Nylander KB, Lauer AK, Cepurna WO, Johnson E : Glaucoma drops control intraocular pressure and protect optic nerves in a rat model of glaucoma. Invest Ophthalmol Vis Sci 39 : 526-531, 1998.
26. Johnson EC, Morrison JC, Farrell S, Deppmeier L, Moore CG, Mcginty MR : The effect of chronically elevated intraocular pressure on the rat optic nerve head extracellular matrix. Exp Eye Res 62 : 663-674, 1996.
27. Morrison JC, Moore CG, Deppmeier LMH, Gold BG, Meshul CK, Johnson EC : A rat model of chronic pressure - induced optic nerve damage. Exp Eye Res 64 :85-96, 1997.
28. Selles-Navarro I, Villegas-Perez MP, Salvador-Suva M, Ruiz-Gomez JM, Vidal-Sanz M : Retinal ganglion cell death after different transient periods of pressure - induced ischemia and survival intervals. Invest Ophthalmol Vis Sci 37 : 2002-2014, 1996.
29. Berkelaar M, Clarke DB, Wang YC, Bray GM, Aguayo AJ : Axotomy results in delayed death and apoptosis of retinal ganglion cells in adult rats. J Neurosci 14 : 4368-4374, 1994.
30. Villegas-Perez MP, Lawrence JM, Vidal-Sanz M, Lavail MM, Lund RD : Ganglion cell loss in RCS rat retina : A result of compression of axons by contracting intraretinal vessels linked to the pigment epithelium. J Comp Neurol 392 : 58-77, 1998.
31. Yoles E, Schwartz M : Degeneration of spared axons following partial white matter lesion : Implications for optic nerve neuropathies. Exp Neurol 153 : 1-7, 1998.
32. Johansson J : Inhibition and recovery of retrograde axoplasmic transport in rat optic nerve during and after elevated IOP in vivo. Exp Eye Res 46 : 223-227, 1988.
33. Neufeld AH : New conceptual approaches for pharmacological neuroprotection in glaucomatous neuronal degeneration. J Glaucoma 7 : 434-438, 1998.
34. Chaudhary P, Ahmed F, Sharma SC : MK 801 - a neuroprotectant in rat hypertensive eyes. Brain Res 792 : 154-158, 1998.