Epistasis between new mutations and genetic background and a test of genetic canalization

Evolution

Volumn 55, Issue 9, 2001, Pages 1746-1752

  Elena, Santiago F ^a   Lenski, Richard E ^b  

^a UNIVERSITY OF VALENCIA   (Spain)

^b MICHIGAN STATE UNIVERSITY   (United States)

Author keywords

Epistasis; Escherichia coli; Fitness; Genetic canalization; Mutation

Indexed keywords

EPISTASIS; GENE INTERACTION; GENE MUTATION; GENETIC CORRELATION; GENETIC TRANSDUCTION; INSERTIONAL MUTAGENESIS; MOLECULAR EVOLUTION; MOLECULAR GENETICS;

EPISTASIS; EVOLUTION; MUTATION;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI;

EID: 0034761862     PISSN: 00143820     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.0014-3820.2001.tb00824.x     Document Type: Article

References (63)

1. Robustness in simple biochemical networks
2. Evidence for non-allelic gene interaction in determining yield, ear height, and kernel row number in corn
3. Virulence of antibiotic-resistant Salmonella typhimurium
4. Evolution by small steps and rugged landscapes in the RNA virus φ6
5. Epistasis as a source of increased additive genetic variance at population bottlenecks
6. Additive by additive variance with inbreeding and linkage
7. Amelioration of the deleterious pleiotropic effects of an adaptive mutation in Bacillus subtilis
8. The population genetics of ecological specialization in evolving E. coli populations
9. Mechanisms causing rapid and parallel losses of ribose catabolism in evolving populations of E. coli B
10. The genetics of speciation
11. A critique of Sewall Wright's shifting balance theory of evolution
12. Is Wright's shifting balance process important in evolution?
13. The effect of sex and deleterious mutations on fitness in Chlamydomonas
14. Test of interaction between genetic markers that affect fitness in Aspergillus niger
15. A constant rate of spontaneous mutation in DNA-based microbes
16. Test of synergistic interactions among deleterious mutations in bacteria
17. Punctuated evolution caused by selection of rare beneficial mutations
18. Distribution of fitness effects caused by random insertion mutations in Escherichia coli
19. A dynamical theory of speciation on holey adaptive landscapes
20. Canalization in evolutionary genetics: A stabilizing theory?
21. On the effect of founder events on epistatic genetic variance
22. Dominance and epistasis as components of heterosis
23. The evolution of genetic canalization under fluctuating selection
24. Estimate of the genomic mutation rate deleterious to overall fitness in E. coli
25. Interactions in fitness between lethal genes in heterozygous condition in Drosophila melanogaster
26. Uses of transposons with emphasis on Tn10
27. Selection against harmful mutations in large sexual and asexual populations
28. Deleterious mutations as an evolutionary factor. II. Facultative apomixis and selfing
29. Haploidy or diploidy: Which is better?
30. Experimental studies of pleiotropy and epistasis in Escherichia coli. II. Compensation for maladaptive effects associated with resistance to virus T4
31. Dynamics of adaptation and diversification: A 10,000-generation experiment with bacterial populations
32. Long-term experimental evolution in Escherichia coli. I. Adaptation and divergence during 2000 generation
33. Genetic analysis of a plasmid-encoded, host genotype-specific enhancement of bacterial fitness
34. Generalized transduction
35. The effect of genetic background on the fitness of diazinon resistance genotypes of the Australian sheep blowfly, Lucilia cuprina
36. Pervasive compensatory adaptation in Escherichia coli
37. The genetic structure of natural populations of Drosophila melanogaster. VII. Synergistic interaction of spontaneous mutant polygenes controlling viability
38. Evolution of genetic redundancy
39. Mutation and sex in a competitive world
40. A spatially explicit stochastic model demonstrates the feasibility of Wright's shifting balance theory
41. Genomic evolution during a 10,000-generation experiment with bacteria
42. Analyzing tables of statistical tests
43. Hsp90 as a capacitor for morphological evolution
44. Canalization: Genetic and developmental aspects
45. Long-term experimental evolution in Escherichia coli. IX. Characterization of insertion sequence-mediated mutations and rearrangements
46. Adaptation to the fitness costs of antibiotic resistance in Escherichia coli
47. Rapid decline of fitness in panmictic populations of Drosophila melanogaster maintained under relaxed natural selection
48. The occurrence and significance of epistatic variance for quantitative characters and its measurement in haploids
49. Evolution of high mutation rates in experimental populations of E. coli
50. Effect of epistasis on grain yield in maize
51. Fitness sensitivity and the canalization of life-history traits
52. Long-term experimental evolution in Escherichia coli. IV. Targets of selection and the specificity of adaptation
53. Canalization of development and genetic assimilation of acquired characters
54. The theories of Fisher and Wright in the context of metapopulations: When nature does many small experiments
55. Redundant gene functions and natural selection
56. Viral RNA and evolved mutational robustness
57. A population genetic theory of canalization
58. The exquisite corpse: A shifting view of the shifting balance
59. Multiple fitness peaks and epistasis
60. Evolution of digital organisms at high mutation rate leads to survival of the flattest
61. Evolution in Mendelian populations