Bicarbonate stimulated phospholipid scrambling induces cholesterol redistribution and enables cholestrol depletion in the sperm plasma membrane

Journal of Cell Science

Volumn 114, Issue 19, 2001, Pages 3543-3555

  Flesch, F M ^a   Brouwers, J F H M ^a   Nievelstein, P F E M ^a   Verkleij, A J ^a   Van Golde, L M G ^a   Colenbrander, B ^a   Gadella, B M ^a  

^a UTRECHT UNIVERSITY   (Netherlands)

Author keywords

Acrosome reaction; Cholesterol efflux; Fertilization; Gamete adhesion; Lipid polarity; Membrane raft; Sperm capacitation

Indexed keywords

ALBUMIN; BICARBONATE; CHOLESTEROL; CYCLIC AMP DEPENDENT PROTEIN KINASE; FILIPIN; LIPOPROTEIN; MEROCYANINE; PHOSPHOLIPID;

ANIMAL CELL; APICAL MEMBRANE; ARTICLE; CELL ACTIVATION; CELL MATURATION; CELL MEMBRANE; CELL SELECTION; CELL STRUCTURE; CELL SUBPOPULATION; CHOLESTEROL TRANSPORT; CONTROLLED STUDY; DEPLETION; EPIDIDYMIS; FERTILIZATION; FLOW CYTOMETRY; MALE; MAMMAL CELL; NONHUMAN; ORGANIZATION; PRIORITY JOURNAL; SPERM; SPERMATOZOON; SWINE;

ACROSOME REACTION; ALBUMINS; ANIMALS; BICARBONATES; CALCIUM; CELL MEMBRANE; CELL SURVIVAL; CHOLESTEROL; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; FILIPIN; FLOW CYTOMETRY; FREEZE FRACTURING; LIPID BILAYERS; MALE; MEMBRANE MICRODOMAINS; PHOSPHOLIPIDS; SPERM CAPACITATION; SPERMATOZOA; SWINE;

EID: 0034759226     PISSN: 00219533     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (56)

1. Yield, characteristics, motility and cAMP content of sperm isolated from seven regions of ram epididymis
2. Flow cytometric detection of bicarbonate-induced changes in lectin binding in boar and ram sperm populations
3. Protamine mediated condensation of DNA in mammalian sperm
4. A rapid method of total lipid extraction and purification
5. Bicarbonate: Carbon-dioxide regulation of sperm capacitation, hyperactivated motility, and acrosome reactions
6. Comparative study of boar sperm coming from the caput, corpus, and cauda regions of the epididymis
7. Quantitative analysis of phosphatidylcholine molecular species using HPLC and light scattering detection
8. Soluble adenylyl cyclase as an evolutionarily conserved bicarbonate sensor
9. Role of cholesterol in sperm capacitation
10. Effect of methyl-beta-cyclodextrin on the acrosomal responsiveness of human sperm
11. Sphingomyelin modulates capacitation of human sperm in vitro
12. Cold-induced ultrastructural changes in bull and boar sperm plasma membranes
13. The spermatozoon
14. Bovine oviductal fluid components and their potential role in sperm cholesterol efflux
15. Cholesterol and caveolae: Structural and functional relationships
16. The use of lectins to characterize plasma membrane preparations from boar spermatozoa: A novel technique to monitor membrane purity and quantity
17. Capacitation induces tyrosine phosphorylation of proteins in the boar sperm plasma membrane
18. Capacitation dependent activation of tyrosine phsphorylation generates two sperm head plasma membrane proteins with high primary affinity for the zona pellucida
19. Plasma-membrane diversity in a highly polarized cell
20. Flow cytometric detection of transbilayer movement of flourescent phospholipid analogues across the boar sperm plasma membrane: Elimination of labeling artifacts
21. Scrambling of phospholipid asymmetry in the apical plasma membrane of acrosome-intact boar sperm cells during in vitro capacitation
22. The capacitation agent bicarbonate induces protein kinase A-dependent changes in phospholipid transbilayer behavior in the sperm plasma membrane
23. Stimulation of partially purified adenylate cyclase from bull sperm by bicarbonate
24. Changes in lipids and membrane anisotropy in human spermatozoa during epididymal maturation
25. Enhanced binding of zona pellucida proteins to the acrosomal region of intact boar spermatozoa in response to fertilizing conditions: A flow cytometric study
26. Capacitation mechanisms, and the role of capacitation as seen in eutherian mammals
27. cAMP-dependent protein kinase control of plasma membrane lipid architecture in boar sperm
28. 2+ influx in boar sperm populations
29. 2, an effector of capacitation, induces a rapid and reversible change in the lipid architecture of boar sperm plasma membranes
30. Identification of sterol acceptors that stimulate cholesterol efflux from human spermatozoa during in vitro capacitation
31. Changes in the lipid content of boar sperm plasma membranes during epididymal maturation
32. Sodium bicarbonate in seminal plasma stimulates the motility of mammalian spermatozoa through direct activation of adenylate cyclase
33. Lipid changes of goat sperm plasma membrane during epididymal maturation on Biochim
34. Stimulation of human sperm capacitation by purified lipid transfer protein
35. Recent advances in membrane cholesterol domain dynamics and intracellular cholesterol trafficking
36. Rat sperm 2B glycoprotein (PH20) contains a C-terminal sequence motif for attachment of a glycosyl phosphatidylinositol anchor. Effects of endoproteolytic cleavage on hyaluronidase activity
37. 2 is not required for zona pellucida- or progesterone-induced acrosomal exocytosis of mouse spermatozoa but is essential for capacitation
38. Lipid rafts and signal transduction
39. Improved high-performance liquid chromatographic method for the separation and quantification of lipid classes: Application to fish lipids
40. Caveolins, liquid-ordered domains, and signal transduction
41. 2 for fertilization of pig oocytes in vitro, and synergism with caffeine
42. Lipid domains and enzyme activity
43. Detection of calcium ionophore induced membrane changes in dog sperm as a simple method to predict the cryopreservability of dog semen
44. Sphingomyelin hydrolysis to ceramide during the execution phase of apoptosis results from phospholipid scrambling and alters cell-surface morphology
45. The use of in vitro fertilization techniques to investigate the fertilizing ability of bovine sperm with proximal cytoplasmic droplets
46. Maturation of mammalian spermatozoa: Modifications of the acrosome and plasma membrane leading to fertilization
47. Mechanisms of phosphatidylserine exposure, a phagocyte recognition signal, on apoptotic T lymphocytes
48. Freeze-etch electron microscopy of erythrocytes. Acholeplasma laidlawii cells and liposomal membranes after the action of filipin and amphotericin B
49. Regulation of protein phosphorylation during sperm capacitation
50. Capacitation of mouse spermatozoa. I. Correlation between the capacitation state and protein tyrosine phosphorylation
51. Capacitation of mouse spermatozoa. II. Protein tyrosine phosphorylation and capacitation are regulated by a cAMP-dependent pathway
52. Cholesterol efflux-mediated signal transduction in mammalian sperm - Beta-cyclodextrins initiate transmembrane signaling leading to an increase in protein tyrosine phosphorylation and capacitation
53. Cholesterol efflux-mediated signal transduction in mammalian sperm: Cholesterol release signals an increase in protein tyrosine phosphorylation during mouse sperm capacitation
54. Back and forth: The regulation and function of transbilayer phospholipid movement in eukaryotic cells
55. Mammalian fertilization
56. Unesterified cholesterol content of human sperm regulates the response of the acrosome to the agonist, progesterone