Unesterified cholesterol content of human sperm regulates the response of the acrosome to the agonist, progesterone

Biology of Reproduction

Volumn 55, Issue 1, 1996, Pages 19-24

  Zarintash, Renee J ^a   Cross, Nicholas L ^a  

^a OKLAHOMA STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHOLESTEROL; PROGESTERONE;

ACROSOME; ACROSOME REACTION; ARTICLE; CULTURE MEDIUM; HUMAN; HUMAN CELL; MALE; PRIORITY JOURNAL; REGULATORY MECHANISM; SEMINAL PLASMA; SPERM; SPERMATOZOON CAPACITATION; SPERMATOZOON MOTILITY;

EID: 0029813137     PISSN: 00063363     EISSN: None     Source Type: Journal    
DOI: 10.1095/biolreprod55.1.19     Document Type: Article

References (44)

1. Yanagimachi R. Mammalian fertilization. In: Knobil E, Neill JD (eds.), The Physiology of Reproduction, 2nd ed. New York: Raven Press; 1994: 189-317.
2. Chang MC. A detrimental effect of seminal plasma on the fertilizing capacity of sperm. Nature (Lond) 1957; 179:258-259.
3. Oliphant G, Reynolds AB, Thomas TS. Sperm surface components involved in the control of the acrosome reaction. Am J Anat 1985; 174:269-284.
4. Coronel CE, Lardy HA. Functional properties of caltrin proteins from seminal vesicle of the guinea pig. Mol Reprod Dev 1992; 33:74-80.
5. Davis BK, Niwa K. Inhibition of mammalian fertilization in vitro by membrane vesicles from seminal plasma. Proc Soc Exp Biol Med 1974; 146:11-16.
6. Shi QX, Zhong CL, Ye Z, Liu LC. Spermine - an inhibition of in vitro capacitation of human sperm. Chin Sci Bull 1989; 34:1820-1825.
7. Riffo M, Leiva S, Astudillo J. Effect of zinc on human sperm motility and the acrosome reaction. Int J Androl 1992; 15:229-237.
8. Davis BK. Inhibition of fertilizing capacity in mammalian spermatozoa by natural and synthetic vesicles. In: Kabara J (ed.), Symposium on the Pharmacological Effect of Lipids. Champaign, IL: The American Oil Chemist's Society; 1978: 145-157.
9. Davis BK. Inhibitory effect of synthetic phospholipid vesicles containing cholesterol on the fertilizing ability of rabbit spermatozoa. Proc Soc Exp Biol Med 1976; 152:257-261.
10. Go KJ, Wolf DP. Albumin-mediated changes in sperm sterol content during capacitation. Biol Reprod 1985; 32:145-153.
11. Bleau G, Vandenheuvel WJA, Andersen OF, Gwatkin RBL. Desmosteryl sulfate of hamster spermatozoa, a potent inhibitor of capacitation in vitro. J Reprod Fertil 1975; 43:175-178.
12. Fayrer-Hosken RA, Brackett BG, Brown J. Reversible inhibition of rabbit sperm-fertilizing ability by cholesterol sulfate. Biol Reprod 1987; 36:878-883.
13. Davis BK. Influence of serum albumin on the fertilizing ability in vitro of rat spermatozoa. Proc Soc Exp Biol Med 1976; 151:240-243.
14. Benoff S, Cooper GW, Hurley I, Mandel FS, Rosenfeld DL. Anti-sperm antibody binding to human sperm inhibits capacitation-induced changes in the levels of plasma membrane sterols. Am J Reprod Immunol 1993; 30:113-130.
15. Davis BK. Interaction of lipids with the plasma membrane of sperm cells. I. The antifertilization action of cholesterol. Archiv Androl 1980; 5:249-254.
16. Flemming AD, Yanagimachi R. Effects of various lipids on the acrosome reaction and fertilizing capacity of guinea pig spermatozoa, with special reference to the possible involvement of lysophospholipid in the acrosome reaction. Gamete Res 1981; 4:253-273.
17. Davis BK, Byrne R, Hungund B. Studies on the mechanism of capacitation. II. Evidence for lipid transfer between plasma membrane of rat sperm and serum albumin during capacitation in vitro. Biochim Biophys Acta 1979; 558:257-266.
18. Benoff S, Hurley I, Cooper GW, Mandel FS, Rosenfeld DL, Hershlag A. Head-specific mannose ligand receptor expression in human spermatozoa is dependent on capacitation-associated membrane cholesterol loss. Hum Reprod 1993; 8:2141-2154.
19. Benoff S, Hurley I, Cooper GW, Mandel FS, Hershlag A, Scholl GM, Rosenfeld DL. Fertilization potential in vitro is correlated with head-specific mannose ligand receptor expression, acrosome status and membrane cholesterol content. Hum Reprod 1993; 8:2155-2166.
20. Davis BK, Byrne R, Bedigan K. Studies on the mechanism of capacitation: Albumin-mediated changes in plasma membrane lipids during in vitro incubation of rat sperm cells. Proc Natl Acad Sci USA 1980; 77:1546-1550.
21. Sugkraroek P, Kates M, Leader A, Tanphaichitr N. Levels of cholesterol and phospholipids in freshly ejaculated sperm and Percoll gradient pelleted sperm from fertile and unexplained infertile men. Fertil Steril 1991; 55:820-827.
22. Hamamah S, Lanson M, Barthelemy C, Garrigue MA, Muh FP, Royere D, Lansac J. Analysis of the lipid content and the motility of human sperm after follicular fluid treatment. Andrologia 1995; 27:91-97.
23. Ehrenwald E, Parks JE, Foote RH. Cholesterol efflux from bovine sperm. I. Induction of the acrosome reaction with lysophosphatidyl choline after reducing sperm cholesterol. Gamete Res 1988; 20:145-157.
24. Ehrenwald E, Parks JE, Foote RH. Cholesterol efflux from bovine sperm: II. Effect of reducing sperm cholesterol on penetration of zona free hamster and in vitro matured bovine ova. Gamete Res 1988; 20: 413-420.
25. Cross NL. Multiple effects of seminal plasma on the acrosome reaction of human sperm. Mol Reprod Dev 1993; 35:316-323.
26. Cross NL. Human seminal plasma prevents sperm from becoming acrosomally responsive to the agonist, progesterone; cholesterol is the major inhibitor. Biol Reprod 1996; 54:138-145.
27. Siiteri JE, Dandekar P, Meizel S. Human sperm acrosome reaction-initiating activity associated with the human cumulus oophorus and mural granulosa cells. J Exp Zool 1988; 246:71-80.
28. Suarez SS, Wolf DP, Meizel S. Induction of the acrosome reaction in human spermatozoa by a fraction of human follicular fluid. Gamete Res 1986; 14:107-121.
29. Cross NL. Phosphatidylcholine enhances the acrosomal responsiveness of human sperm. J Androl 1994; 15:484-488.
30. Bligh EG, Dyer WJ, A rapid method of total lipid extraction and purification. Can J Biochem Physiol 1959; 37:911-917.
31. Kates M. Techniques of Lipidology. Amsterdam: North-Holland Publishing Co.; 1986.
32. Lin DS, Connor WE, Wolf DP, Neuringer M, Hachey DL. Unique lipids of primate spermatozoa: desmosterol and docosahexaenoic acid. J Lipid Res 1993; 34:491-499.
33. Lalumiere G, Bleau G, Chapdelaine A, Roberts KD. Cholesteryl sulfate and sterol sulfatase in the human reproductive tract. Steroids 1976; 27:247-260.
34. Langlais J, Roberts KD. A molecular membrane model of sperm capacitation and the acrosome reaction of mammalian spermatozoa. Gamete Res 1985; 12:183-224.
35. Ravnik SE, Zarutskie PW, Muller CH. Purification and characterization of a human follicular fluid lipid transfer protein that stimulates human sperm capacitation. Biol Reprod 1992; 47:1126-1133.
36. Yeagle PL. The biophysics and cell biology of cholesterol: an hypothesis for the essential role of cholesterol in mammalian cells. In: Finegold L (ed.), Cholesterol in Membrane Models. Boca Raton, FL: CRC Press; 1993: 1-12.
37. Mack SR, Everingham J, Zaneveld LJD. Isolation and partial characterization of the plasma membrane from human spermatozoa. J Exp Zool 1986; 240:127-136.
38. Tesarík J, Fléchon JE. Distribution of sterols and anionic lipids in human sperm plasma membrane: effects of in vitro capacitation. J Ultrastruct Mol Struct Res 1986; 97:227-237.
39. Friend D. Freeze-fracture alterations in guinea pig sperm membranes preceding gamete fusion. In: Gilula NB (ed.), Membrane-Membrane Interactions. New York, NY: Raven Press; 1980: 153-165.
40. Suzuki F, Yanagimachi R. Changes in the distribution of intramembranous particles and filipin-reactive membrane sterols during in vitro capacitation of golden hamster spermatozoa. Gamete Res 1989; 23: 335-347.
41. Ehrenwald E, Foote RH, Parks JE. Bovine oviductal fluid components and their potential role in sperm cholesterol efflux. Mol Reprod Dev 1990; 25:195-204.
42. Parrish JJ, Susko-Parrish JL, Handrow RR, Sims MM, First NL. Capacitation of bovine spermatozoa by oviduct fluid. Biol Reprod 1989; 40:1020-1025.
43. Davis BK. Uterine fluid proteins bind sperm cholesterol during capacitation in the rabbit. Experientia 1982; 38:1063-1064.
44. Langlais J, Kan FW, Granger L, Raymond L, Bleau G, Roberts KD. Identification of sterol acceptors that stimulate cholesterol efflux from human spermatozoa during in vitro capacitation. Gamete Res 1988; 20:185-201.