Effects of retinoids on the TGF-β system and extracellular matrix in experimental glomerulonephritis

Journal of the American Society of Nephrology

Volumn 12, Issue 11, 2001, Pages 2300-2309

  Morath, C ^a   Dechow, C ^a   Lehrke, I ^a   Haxsen, V ^a   Waldherr, R ^a   Floege, J ^a   Ritz, E ^a   Wagner, J ^a  

^a UNIVERSITY HOSPITAL HEIDELBERG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGEN TYPE 3; COLLAGEN TYPE 4; FIBRONECTIN; ISOTRETINOIN; RETINOIC ACID; RETINOID; SCLEROPROTEIN; TRANSFORMING GROWTH FACTOR ALPHA RECEPTOR; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA1;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; EXTRACELLULAR MATRIX; GENE EXPRESSION; GENE OVEREXPRESSION; GLOMERULONEPHRITIS; IMMUNOHISTOCHEMISTRY; MALE; NEPHRITIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SHEAR STRESS;

EID: 0034758667     PISSN: 10466673     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (50)

1. Transforming growth factor beta in tissue fibrosis
2. Glomerular endothelial cell proteoglycans-regulation by TGF-beta 1
3. Production of extracellular matrix by glomerular epithelial cells is regulated by transforming growth factor-beta 1
4. Transforming growth factor beta modulates the expression of collagenase and metalloproteinase inhibitor
5. Increased expression of TGF-beta 1 mRNA in the obstructed kidney of rats with unilateral ureteral ligation
6. Prostaglandin E1 inhibits collagen expression in anti-thymocyte antibody-induced glomerulonephritis: Possible role of TGF beta
7. Modulation of experimental mesangial proliferative nephritis by interferon-gamma
8. Elevated expression of transforming growth factor-beta and proteoglycan production in experimental glomerulonephritis. Possible role in expansion of the mesangial extracellular matrix
9. Targeting TGF-beta overexpression in renal disease: Maximizing the antifibrotic action of angiotensin II blockade
10. Inhibition of TGF-beta 1 expression by antisense oligonucleotides suppressed extracellular matrix accumulation in experimental glomerulonephritis
11. Suppression of experimental glomerulonephritis by antiserum against transforming growth factor beta 1
12. Role of retinoids in renal development: Pathophysiological implication
13. Retinoic acid receptors in normal growth and development
14. A decade of molecular biology of retinoic acid receptors
15. Retinoic acids inhibit inducible nitric oxide synthase expression in mesangial cells
16. Retinoid receptor expression and all-trans retinoic acid-mediated growth inhibition in vascular smooth muscle cells
17. Retinoic acid receptors and retinoid X receptor-alpha downregulate the transforming growth factor-beta 1 promoter by antagonizing AP-1 activity
18. Anti-AP-1 activity of all-trans retinoic acid in glomerular mesangial cells
19. Ligand-activated retinoic acid receptor inhibits AP-1 transactivation by disrupting c-Jun/c-Fos dimerization
20. Retinoic acid reduces glomerular injury in a rat model of glomerular damage
21. Angiotensin II receptor type 1 gene expression in human glomerulonephritis and diabetes mellitus
22. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
23. Differential regulation of the expression of transforming growth factor-betas 1 and 2 by retinoic acid, epidermal growth factor, and dexamethasone in NRK-49F and A549 cells
24. Mechanistic interrelationships between two superfamilies: The steroid/retinoid receptors and transforming growth factor-beta
25. Differential regulation of the expression of transforming growth factor-beta mRNAs by growth factors and retinoic acid in chicken embryo chondrocytes, myocytes, and fibroblasts
26. Steroids, retinoids, and wound healing
27. Suppression of renal inflammation with vitamins A and E in ascending pyelonephritis in rats
28. Complex regulation of TGF beta expression by retinoic acid in the vitamin A-deficient rat
29. Interactions between retinoids and TGF betas in mouse morphogenesis
30. Gene therapy by transforming growth factor-beta receptor-IgG Fc chimera suppressed extracellular matrix accumulation in experimental glomerulonephritis
31. Glomerulosclerosis induced by in vivo transfection of transforming growth factor-beta or platelet-derived growth factor gene into the rat kidney
32. Renal expression of genes that promote interstitial inflammation and fibrosis in rats with protein-overload proteinuria
33. Overexpression of chemokines, fibrogenic cytokines, and myofibroblasts in human membranous nephropathy
34. TGF-beta receptors are diminished after retinoid exposure in rat liver epithelial cells
35. Retinoic acid is a negative regulator of AP-1-responsive genes
36. A transforming growth factor beta type I receptor that signals to activate gene expression
37. Cloning of a type I TGF-beta receptor and its effect on TGF-beta binding to the type II receptor
38. SMADs: Mediators and regulators of TGF-beta signaling
39. Mechanism of activation of the TGF-beta receptor
40. Cholesterol, macrophages, and gene expression of TGF-beta 1 and fibronectin during nephrosis
41. Shear stress induces transforming growth factor-beta 1 release by arterial endothelial cells
42. Retinoids inhibit the actions of angiotensin II on vascular smooth muscle cells
43. Role of AP-1 complex in angiotensin II-mediated transforming growth factor-beta expression and growth of smooth muscle cells: Using decoy approach against AP-1 binding site
44. Retinoic acid down-regulation of fibronectin and retinoic acid receptor alpha proteins in NIH-3T3 cells. Blocks of this response by ras transformation
45. Retinoic acid inhibits basement membrane protein biosynthesis while stimulating dome formation by Madin Darby canine kidney cells in hormonally defined serum-free medium
46. The late retinoic acid induction of laminin B1 gene transcription involves RAR binding to the responsive element
47. A retinoic acid-responsive element is present in the 5′ flanking region of the laminin B1 gene
48. Heparin suppresses mesangial cell proliferation and matrix expansion in experimental mesangioproliferative glomerulonephritis
49. Increased synthesis of extracellular matrix in mesangial proliferative nephritis
50. Modulation of collagen synthesis and cell proliferation by retinoids in human skin fibroblasts