Leptin in children with newly diagnosed type 1 diabetes: Effect of insulin therapy

International Journal of Experimental Diabetes Research

Volumn 2, Issue 2, 2001, Pages 121-127

  McCormick, K L ^a   Mick, G J ^a   Butterfield, L ^a   Ross, H ^a   Parton, E ^a   Totka, J ^a  

^a UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

Author keywords

Insulin; Leptin; Type 1 diabetes

Indexed keywords

HEMOGLOBIN A1C; INSULIN; LEPTIN;

ACUTE DISEASE; ADOLESCENT; AMBULATORY CARE; ARTICLE; BODY MASS; CHILD; CHILDHOOD DISEASE; CLINICAL ARTICLE; CONTROLLED STUDY; DIABETIC KETOACIDOSIS; DISEASE SEVERITY; FEMALE; HEMOGLOBIN DETERMINATION; HORMONE BLOOD LEVEL; HUMAN; HYPOINSULINEMIA; INSULIN BLOOD LEVEL; INSULIN DEFICIENCY; INSULIN DEPENDENT DIABETES MELLITUS; INSULIN TREATMENT; MALE; PRIORITY JOURNAL; STATISTICAL ANALYSIS; WEIGHT GAIN;

ADOLESCENT; BLOOD GLUCOSE; BODY MASS INDEX; CHILD; CHILD, PRESCHOOL; DIABETES MELLITUS, TYPE 1; HEMOGLOBIN A, GLYCOSYLATED; HUMANS; HYPOGLYCEMIC AGENTS; INSULIN; LEPTIN; TIME FACTORS;

EID: 0034755532     PISSN: 15604284     EISSN: None     Source Type: Journal    
DOI: 10.1155/EDR.2001.121     Document Type: Article

References (39)

1. Positional cloning of the mouse obese gene and its human homologue
2. The stomach is a source of leptin
3. Recombinant mouse ob protein: Evidence for a peripheral signal linking adiposity and central neural networks
4. Leptin levels in human and rodent: Measurement of plasma leptin and ob/RNA in obese and weight-reduced subjects
5. Serum immunoreactive-leptin concentrations in normal-weight and obese humans
6. Relation between plasma leptin concentration and body fat, gender, diet, age, and metabolic covariates
7. Tranisent increase in obese gene expression after food or insulin administration
8. Regulation of expression of ob mRNA and protein by glucocorticoids and cAMP
9. Insulin and cortisol promote leptin production in cultured human fat cells
10. Leptin: In search of role(s) in human physiology and pathophysiology
11. Regulation and possible significance of leptin in humans: Leptin in health and disease
12. Plasma leptin and insulin relationships in obese and nonobese humans
13. Effect of hyperinsulinemia on plasma leptin concentrations and food intake in rats
14. Supraphysiological hyperinsulinemia increases plasma leptin concentrations after 4h in normal subjects
15. Acute and chronic effect of insulin on leptin production in humans. Studies in vivo and in vitro
16. Effects of prolonged hyperinsulinemia on serum leptin in normal human subjects
17. Effect of insulin, metformin and glybenclamide on leptin secretion from rat adipose tissue
18. Insulin and insulin-like growth factor 1 antagonize the stimulation of ob gene expression by dexam-ethasone in cultured rat adipose tissue
19. Multihormonal control of ob gene expression and leptin secretion from cultured human visceral adipose tissue: Increased responsiveness to glucocorticoids in obesity
20. Dexamethasone stimulates leptin release from human adipocytes: Unexpected inhibition by insulin
21. Studies in whole body potassium and whole body nitrogen in newly diagnosed diabetes
22. Leptin synthesis is resistant to acute effects of insulin in insulin-dependent diabetes mellitus patients
23. Effects of hypersinsulinaemia and hypoglycaemia on circulating leptin levels in healthy lean males
24. Insulin increases plasma leptin concentrations in normal subjects and patients with NIDDM
25. Physiological insulinemia acutely modulates plasma leptin
26. Increased ob gene expression leads to elevated plasma leptin concentrations in patients with chronic primary hyperinsulinemia
27. Serum leptin and insulin concentrations in prepubertal lean, obese and insulin-dependent diabetes mellitus children
28. Dual effect of insulin on in vitro leptin secretion by adipose tissue
29. Inhibition of leptin secretion by insulin and metformin in cultured rat adipose tissue
30. Leptin before and after insulin therapy in children with new-onset type I diabetes
31. Changes in plasma leptin during the treatment of diabetes ketoacidosis
32. Changes in free insulin-like growth factor-1 and leptin concentrations during acute metabolic decompensation in insulin withdrawn patients with Type 1 diabetes
33. Evidence for leptin binding to proteins in serum of rodents and humans: Modulation with obesity
34. Leptin: Its pharmacokinetics and tissue distribution
35. Evidence of free and bound leptin in human circulation. Studies in lean and obese subjects and during short-term fasting
36. Inter-organ leptin exchange in humans
37. Plasma leptin concentrations are only transiently increased in nephrectomized rats
38. Interaction of free fatty acid with human leptin