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Volumn 15, Issue 9, 1996, Pages 2196-2207

Rom1p and Rom2p are GDP/GTP exchange proteins (GEPs) for the Rho1p small GTP binding protein in Saccharomyces cerevisiae

Author keywords

GDP; GTP exchange protein; Rho; S.cerevisiae

Indexed keywords

FUNGAL PROTEIN; GLUTATHIONE TRANSFERASE; GUANINE NUCLEOTIDE BINDING PROTEIN; GUANINE NUCLEOTIDE EXCHANGE FACTOR; HYBRID PROTEIN;

EID: 0029920783     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1002/j.1460-2075.1996.tb00573.x     Document Type: Article
Times cited : (188)

References (66)
  • 1
    • 0025294640 scopus 로고
    • CDC42 and CDC43, two additional genes involved in budding and the establishment of cell polarity in the yeast Saccharomyces cerevisiae
    • Adams, A E., Johnson, D.I., Longnecker, R.M., Sloat, B.F. and Pringle, J.R. (1990) CDC42 and CDC43, two additional genes involved in budding and the establishment of cell polarity in the yeast Saccharomyces cerevisiae. J. Cell Biol., 111, 131-142.
    • (1990) J. Cell Biol. , vol.111 , pp. 131-142
    • Adams, A.E.1    Johnson, D.I.2    Longnecker, R.M.3    Sloat, B.F.4    Pringle, J.R.5
  • 2
    • 0027052911 scopus 로고
    • Post-translational processing of rac p21s is important both for their interaction with the GDP/GTP exchange proteins and for their activation of NADPH oxidase
    • Ando, S. et al. (1992) Post-translational processing of rac p21s is important both for their interaction with the GDP/GTP exchange proteins and for their activation of NADPH oxidase. J. Biol. Chem., 267, 25709-25713.
    • (1992) J. Biol. Chem. , vol.267 , pp. 25709-25713
    • Ando, S.1
  • 3
    • 0027255909 scopus 로고
    • Elimination of false positives that arise in using the two-hybrid system
    • Bartel, P., Chien, C.T. Sternglanz, R. and Fields, S. (1993) Elimination of false positives that arise in using the two-hybrid system. Biotechniques, 14, 920-924.
    • (1993) Biotechniques , vol.14 , pp. 920-924
    • Bartel, P.1    Chien, C.T.2    Sternglanz, R.3    Fields, S.4
  • 4
    • 0027732538 scopus 로고
    • Proteins regulating Ras and its relatives
    • Boguski, M.S and McCormick, F. (1993) Proteins regulating Ras and its relatives. Nature, 366, 643-654.
    • (1993) Nature , vol.366 , pp. 643-654
    • Boguski, M.S.1    McCormick, F.2
  • 5
    • 0028081350 scopus 로고
    • Guanine nucleotide exchange regulates membrane translocation of Rac/Rho GTP-binding proteins
    • Bokoch, G.M , Bohl, B.P. and Chuang, T.H. (1994) Guanine nucleotide exchange regulates membrane translocation of Rac/Rho GTP-binding proteins. J. Biol. Chem., 269, 31674-31679.
    • (1994) J. Biol. Chem. , vol.269 , pp. 31674-31679
    • Bokoch, G.M.1    Bohl, B.P.2    Chuang, T.H.3
  • 6
    • 0026026818 scopus 로고
    • The GTPase superfamily: Conserved structure and molecular mechanism
    • Bourne, H.R., Sanders, D.A and McCormick, F. (1991) The GTPase superfamily: conserved structure and molecular mechanism. Nature, 349, 117-127.
    • (1991) Nature , vol.349 , pp. 117-127
    • Bourne, H.R.1    Sanders, D.A.2    McCormick, F.3
  • 7
    • 0020078214 scopus 로고
    • Two differentially regulated mRNAs with different 5′ ends encode secreted with intracellular forms of yeast invertase
    • Carlson, M. and Botstein, D. (1982) Two differentially regulated mRNAs with different 5′ ends encode secreted with intracellular forms of yeast invertase. Cell, 28, 145-154.
    • (1982) Cell , vol.28 , pp. 145-154
    • Carlson, M.1    Botstein, D.2
  • 8
    • 0028266937 scopus 로고
    • Expression cDNA cloning of a novel oncogene with sequence similarity to regulators of small GTP-binding proteins
    • Chan, A.M., McGovern, E.S , Catalano, G., Fleming, T.P. and Miki, T. (1994) Expression cDNA cloning of a novel oncogene with sequence similarity to regulators of small GTP-binding proteins. Oncogene, 9, 1057-1063.
    • (1994) Oncogene , vol.9 , pp. 1057-1063
    • Chan, A.M.1    McGovern, E.S.2    Catalano, G.3    Fleming, T.P.4    Miki, T.5
  • 9
    • 0028915743 scopus 로고
    • GTPase cascades choreographing cellular behavior: Movement, morphogenesis, and more
    • Chant, J. and Stowers, L. (1995) GTPase cascades choreographing cellular behavior: movement, morphogenesis, and more. Cell, 81, 1-4
    • (1995) Cell , vol.81 , pp. 1-4
    • Chant, J.1    Stowers, L.2
  • 10
    • 0028122478 scopus 로고
    • Ras-15A protein shares highly similar dominant-negative biological properties with Ras-17N and forms a stable, guanine-nucleotide resistant complex with CDC25 exchange factor
    • Chen, S.Y., Huff, S.Y., Lai, C.C., Der, C.J and Powers, S. (1994) Ras-15A protein shares highly similar dominant-negative biological properties with Ras-17N and forms a stable, guanine-nucleotide resistant complex with CDC25 exchange factor. Oncogene, 9, 2691-2698.
    • (1994) Oncogene , vol.9 , pp. 2691-2698
    • Chen, S.Y.1    Huff, S.Y.2    Lai, C.C.3    Der, C.J.4    Powers, S.5
  • 11
    • 0025899137 scopus 로고
    • Development of cell polarity in budding yeast
    • Drubin, D.G. (1991) Development of cell polarity in budding yeast Cell, 65, 1093-1096.
    • (1991) Cell , vol.65 , pp. 1093-1096
    • Drubin, D.G.1
  • 12
    • 0024406857 scopus 로고
    • A novel genetic system to detect protein-protein interactions
    • Fields, S. and Song, O (1989) A novel genetic system to detect protein-protein interactions. Nature, 340, 245-246.
    • (1989) Nature , vol.340 , pp. 245-246
    • Fields, S.1    Song, O.2
  • 13
    • 0025073547 scopus 로고
    • Molecular cloning and characterization of a novel type of regulatory protein (GDI) for the rho proteins, ras p21-like small GTP-binding proteins
    • Fukumoto, Y., Kaibuchi, K., Hori, Y., Fujioka, H., Araki, S., Ueda, T., Kikuchi, A. and Takai, Y. (1990) Molecular cloning and characterization of a novel type of regulatory protein (GDI) for the rho proteins, ras p21-like small GTP-binding proteins. Oncogene, 5, 1321-1328.
    • (1990) Oncogene , vol.5 , pp. 1321-1328
    • Fukumoto, Y.1    Kaibuchi, K.2    Hori, Y.3    Fujioka, H.4    Araki, S.5    Ueda, T.6    Kikuchi, A.7    Takai, Y.8
  • 15
    • 0026562884 scopus 로고
    • Improved method for high efficiency transformation of intact yeast cells
    • Gietz, D., Jean, A.S., Woods, R.A. and Schiestl, R.H. (1992) Improved method for high efficiency transformation of intact yeast cells. Nucleic Acids Res., 20, 1425.
    • (1992) Nucleic Acids Res. , vol.20 , pp. 1425
    • Gietz, D.1    Jean, A.S.2    Woods, R.A.3    Schiestl, R.H.4
  • 16
    • 0020645052 scopus 로고
    • Yeast promoters and lacZ fusions designed to study expression of cloned genes in yeast
    • Guarente, L. (1983) Yeast promoters and lacZ fusions designed to study expression of cloned genes in yeast. Methods Enzymol , 101, 181-191.
    • (1983) Methods Enzymol , vol.101 , pp. 181-191
    • Guarente, L.1
  • 17
    • 0028225439 scopus 로고
    • Identification of an invasion-inducing gene, Tiam-1, that encodes a protein with homology to GDP-GTP exchangers for Rho-like proteins
    • Habets, G.G., Scholtes, E H., Zuydgeest, D., van der Kammen, R.A., Stam, J.C., Berns, A. and Collard, J.G. (1994) Identification of an invasion-inducing gene, Tiam-1, that encodes a protein with homology to GDP-GTP exchangers for Rho-like proteins. Cell, 77, 537-549.
    • (1994) Cell , vol.77 , pp. 537-549
    • Habets, G.G.1    Scholtes, E.H.2    Zuydgeest, D.3    Van Der Kammen, R.A.4    Stam, J.C.5    Berns, A.6    Collard, J.G.7
  • 18
    • 0028170820 scopus 로고
    • Small GTP-binding proteins and the regulation of the actin cytoskeleton
    • Hall, A. (1994) Small GTP-binding proteins and the regulation of the actin cytoskeleton. Annu. Rev. Cell Biol., 10, 31-54.
    • (1994) Annu. Rev. Cell Biol. , vol.10 , pp. 31-54
    • Hall, A.1
  • 19
    • 0028021882 scopus 로고
    • Pleckstrin homology domains bind to phosphatidylinositol-4,5-bisphosphate
    • Harlan, J.E , Hajduk, P.J., Yoon, H.S. and Fesik, S W. (1994) Pleckstrin homology domains bind to phosphatidylinositol-4,5-bisphosphate. Nature, 371, 168-170
    • (1994) Nature , vol.371 , pp. 168-170
    • Harlan, J.E.1    Hajduk, P.J.2    Yoon, H.S.3    Fesik, S.W.4
  • 20
    • 0026044409 scopus 로고
    • Catalysis of guanine nucleotide exchange on the CDC42Hs protein by the dbl oncogene product
    • Hart, M.J., Eva, A., Evans, T., Aaronson, S.A. and Cerione, R.A. (1991) Catalysis of guanine nucleotide exchange on the CDC42Hs protein by the dbl oncogene product. Nature, 354, 311-314
    • (1991) Nature , vol.354 , pp. 311-314
    • Hart, M.J.1    Eva, A.2    Evans, T.3    Aaronson, S.A.4    Cerione, R.A.5
  • 21
    • 0027958423 scopus 로고
    • Cellular transformation and guanine nucleotide exchange activity are catalyzed by a common domain on the dbl oncogene product
    • Hart, M.J., Eva, A., Zangrilli, D., Aaronson, S.A., Evans, T., Cerione, R.A and Zheng, Y. (1994) Cellular transformation and guanine nucleotide exchange activity are catalyzed by a common domain on the dbl oncogene product. J. Biol. Chem., 269, 62-65.
    • (1994) J. Biol. Chem. , vol.269 , pp. 62-65
    • Hart, M.J.1    Eva, A.2    Zangrilli, D.3    Aaronson, S.A.4    Evans, T.5    Cerione, R.A.6    Zheng, Y.7
  • 22
    • 0027284220 scopus 로고
    • Human ABR encodes a protein with GAPrac activity and homology to the DBL nucleotide exchange factor domain
    • Heisterkamp, N , Kaartinen, V., van Soest, S , Bokoch, G.M. and Groffen, J. (1993) Human ABR encodes a protein with GAPrac activity and homology to the DBL nucleotide exchange factor domain. J. Biol. Chem., 268, 16903-16906.
    • (1993) J. Biol. Chem. , vol.268 , pp. 16903-16906
    • Heisterkamp, N.1    Kaartinen, V.2    Van Soest, S.3    Bokoch, G.M.4    Groffen, J.5
  • 23
    • 0021253525 scopus 로고
    • Unidirectional digestion with exonuclease III creates targeted breakpoints for DNA sequencing
    • Henikoff, S. (1984) Unidirectional digestion with exonuclease III creates targeted breakpoints for DNA sequencing. Gene, 28, 351-359.
    • (1984) Gene , vol.28 , pp. 351-359
    • Henikoff, S.1
  • 24
    • 85016731055 scopus 로고
    • Using PCR to engineer DNA
    • Erlich, H.A. (ed), Macmillian Publishers Ltd, UK
    • Higuchi, R. (1989) Using PCR to engineer DNA. In Erlich, H.A. (ed), PCR Technology, Macmillian Publishers Ltd, UK, pp. 61-70
    • (1989) PCR Technology , pp. 61-70
    • Higuchi, R.1
  • 25
    • 0022781503 scopus 로고
    • Yeast/E.coli shuttle vectors with multiple unique restriction sites
    • Hill, J.E , Myers, A.M., Koerner, T.J. and Tzagoloff, A. (1986) Yeast/E.coli shuttle vectors with multiple unique restriction sites. Yeast, 2, 163-167.
    • (1986) Yeast , vol.2 , pp. 163-167
    • Hill, J.E.1    Myers, A.M.2    Koerner, T.J.3    Tzagoloff, A.4
  • 26
    • 9244264513 scopus 로고
    • Constraint based alignment editor with automatic aligner and motif dictionary retriever
    • Hirosawa, M., Totoki, Y. and Ishikawa, M. (1993) Constraint based alignment editor with automatic aligner and motif dictionary retriever. Proc. Genome Informatics, 4, 411-117.
    • (1993) Proc. Genome Informatics , vol.4 , pp. 411-1117
    • Hirosawa, M.1    Totoki, Y.2    Ishikawa, M.3
  • 27
    • 0028110120 scopus 로고
    • A novel oncogene, ost, encodes a guanine nucleotide exchange factor that potentially links Rho and Rac signaling pathways
    • Horii, Y., Beeler, J.F., Sakaguchi, K., Tachibana, M. and Miki, T. (1994) A novel oncogene, ost, encodes a guanine nucleotide exchange factor that potentially links Rho and Rac signaling pathways. EMBO J., 13, 4776-4786
    • (1994) EMBO J. , vol.13 , pp. 4776-4786
    • Horii, Y.1    Beeler, J.F.2    Sakaguchi, K.3    Tachibana, M.4    Miki, T.5
  • 28
    • 0025363198 scopus 로고
    • Molecular characterization of CDC42, a Saccharomyces cerevisiae gene involved in the development of cell polarity
    • Johnson, D.I. and Pringle, J.R. (1990) Molecular characterization of CDC42, a Saccharomyces cerevisiae gene involved in the development of cell polarity. J. Cell Biol., 111, 143-152.
    • (1990) J. Cell Biol. , vol.111 , pp. 143-152
    • Johnson, D.I.1    Pringle, J.R.2
  • 29
    • 0026341908 scopus 로고
    • Molecular cloning of the cDNA for stimulatory GDP/GTP exchange protein for smg p21s (ras p21-like small GTP-binding proteins) and characterization of stimulatory GDP/GTP exchange protein
    • Kaibuchi, K., Mizuno, T., Fujioka, H., Yamamoto, T., Kishi, K., Fukumoto, Y., Hori, Y and Takai, Y. (1991) Molecular cloning of the cDNA for stimulatory GDP/GTP exchange protein for smg p21s (ras p21-like small GTP-binding proteins) and characterization of stimulatory GDP/GTP exchange protein. Mol. Cell. Biol., 11, 2873-2880.
    • (1991) Mol. Cell. Biol. , vol.11 , pp. 2873-2880
    • Kaibuchi, K.1    Mizuno, T.2    Fujioka, H.3    Yamamoto, T.4    Kishi, K.5    Fukumoto, Y.6    Hori, Y.7    Takai, Y.8
  • 30
    • 0026031054 scopus 로고
    • Loss of the amino-terminal helix-loop-helix domain of the van proto-oncogene activates its transforming potential
    • Katzav, S., Cleveland, J.L., Heslop, H.E. and Pulido, D. (1991) Loss of the amino-terminal helix-loop-helix domain of the van proto-oncogene activates its transforming potential. Mol. Cell Biol., 11, 1912-1920
    • (1991) Mol. Cell Biol. , vol.11 , pp. 1912-1920
    • Katzav, S.1    Cleveland, J.L.2    Heslop, H.E.3    Pulido, D.4
  • 31
    • 0023871866 scopus 로고
    • Purification and characterization of a novel GTP-binding protein with a molecular weight of 24,000 from bovine brain membranes
    • Kikuchi, A., Yamashita, T., Kawata, M., Yamamoto, K., Ikeda, K , Tanimoto, T. and Takai, Y. (1988) Purification and characterization of a novel GTP-binding protein with a molecular weight of 24,000 from bovine brain membranes. J. Biol. Chem., 263, 2897-2904.
    • (1988) J. Biol. Chem. , vol.263 , pp. 2897-2904
    • Kikuchi, A.1    Yamashita, T.2    Kawata, M.3    Yamamoto, K.4    Ikeda, K.5    Tanimoto, T.6    Takai, Y.7
  • 32
    • 0026664194 scopus 로고
    • Functional interactions of stimulatory and inhibitory GDP/GTP exchange proteins and their common substrate small GTP-binding protein
    • Kikuchi, A., Kuroda, S., Sasaki, T., Kotani, K., Hirata, K., Katayama, M. and Takai, Y. (1992) Functional interactions of stimulatory and inhibitory GDP/GTP exchange proteins and their common substrate small GTP-binding protein. J. Biol. Chem., 267, 14611-14615.
    • (1992) J. Biol. Chem. , vol.267 , pp. 14611-14615
    • Kikuchi, A.1    Kuroda, S.2    Sasaki, T.3    Kotani, K.4    Hirata, K.5    Katayama, M.6    Takai, Y.7
  • 34
    • 0027502176 scopus 로고
    • Influence of guanine nucleotides on complex formation between Ras and CDC25 proteins
    • Lai, C.C. Boguski, M., Broek, D. and Powers, S (1993) Influence of guanine nucleotides on complex formation between Ras and CDC25 proteins. Mol. Cell. Biol., 13, 1345-1352.
    • (1993) Mol. Cell. Biol. , vol.13 , pp. 1345-1352
    • Lai, C.C.1    Boguski, M.2    Broek, D.3    Powers, S.4
  • 35
    • 0027526303 scopus 로고
    • cDNA cloning of a human mRNA preferentially expressed in hematopoietic cells and with homology to a GDP-dissociation inhibitor for the rho GTP-binding proteins
    • Lelias, J.M., Adra, C.N., Wulf, G M., Guillemot, J C , Khagad, M., Caput, D. and Lim, B. (1993) cDNA cloning of a human mRNA preferentially expressed in hematopoietic cells and with homology to a GDP-dissociation inhibitor for the rho GTP-binding proteins. Proc. Natl Acad. Sci. USA, 90, 1479-1483.
    • (1993) Proc. Natl Acad. Sci. USA , vol.90 , pp. 1479-1483
    • Lelias, J.M.1    Adra, C.N.2    Wulf, G.M.3    Guillemot, J.C.4    Khagad, M.5    Caput, D.6    Lim, B.7
  • 36
    • 0023293818 scopus 로고
    • Characterization of two members of the rho gene family from the yeast Saccharomyces cerevisiae
    • Madaule, P., Axel, R. and Myers, A.M. (1987) Characterization of two members of the rho gene family from the yeast Saccharomyces cerevisiae. Proc. Natl Acad. Sci. USA, 84, 779-783
    • (1987) Proc. Natl Acad. Sci. USA , vol.84 , pp. 779-783
    • Madaule, P.1    Axel, R.2    Myers, A.M.3
  • 37
    • 0026523616 scopus 로고
    • Cloning by functional complementation of a mouse cDNA encoding a homologue of CDC25, a Saccharomyces cerevisiae RAS activator
    • Martegani, E., Vanoni, M., Zippel, P., Coccetti, P., Brambilla, R., Ferrari, C., Sturani, E. and Alberghina, L. (1992) Cloning by functional complementation of a mouse cDNA encoding a homologue of CDC25, a Saccharomyces cerevisiae RAS activator. EMBO J., 11, 2151-2157.
    • (1992) EMBO J. , vol.11 , pp. 2151-2157
    • Martegani, E.1    Vanoni, M.2    Zippel, P.3    Coccetti, P.4    Brambilla, R.5    Ferrari, C.6    Sturani, E.7    Alberghina, L.8
  • 38
    • 0027992663 scopus 로고
    • Molecular cloning and characterization of yeast rho GDP dissociation inhibitor
    • Masuda, T , Tanaka, K , Nonaka, H., Yamochi, W., Maeda, A. and Takai, Y (1994) Molecular cloning and characterization of yeast rho GDP dissociation inhibitor. J. Biol. Chem., 269, 19713-19718.
    • (1994) J. Biol. Chem. , vol.269 , pp. 19713-19718
    • Masuda, T.1    Tanaka, K.2    Nonaka, H.3    Yamochi, W.4    Maeda, A.5    Takai, Y.6
  • 39
    • 0026484397 scopus 로고
    • Yeast RHO3 and RHO4 ras superfamily genes are necessary for bud growth, and their defect is suppressed by a high dose of bud formation genes CDC42 and BEMI Mol
    • Matsui, Y. and Toh-E.A. (1992) Yeast RHO3 and RHO4 ras superfamily genes are necessary for bud growth, and their defect is suppressed by a high dose of bud formation genes CDC42 and BEMI Mol. Cell. Biol., 12, 5690-5699.
    • (1992) Cell. Biol. , vol.12 , pp. 5690-5699
    • Matsui, Y.1    Toh, E.A.2
  • 40
    • 0023091932 scopus 로고
    • Baculovirus expression vectors: The requirements for high level expression of proteins, including glycoproteins
    • Matsuura, Y., Possee, R.D., Overton, H.A. and Bishop, D.H. (1987) Baculovirus expression vectors: the requirements for high level expression of proteins, including glycoproteins. J. Gen. Virol , 68, 1233-1250.
    • (1987) J. Gen. Virol , vol.68 , pp. 1233-1250
    • Matsuura, Y.1    Possee, R.D.2    Overton, H.A.3    Bishop, D.H.4
  • 42
    • 0026050653 scopus 로고
    • A stimulatory GDP/GTP exchange protein for smg p21 is active on the post-translationally processed form of c-Ki-ras p21 and rhoA p21
    • Mizuno, T., Kaibuchi, K , Yamamoto, T., Kawamura, M., Sakoda, T., Fujioka, H., Matsuura, Y. and Takai, Y. (1991) A stimulatory GDP/GTP exchange protein for smg p21 is active on the post-translationally processed form of c-Ki-ras p21 and rhoA p21. Proc Natl Acad Sci. USA, 88, 6442-6446.
    • (1991) Proc Natl Acad Sci. USA , vol.88 , pp. 6442-6446
    • Mizuno, T.1    Kaibuchi, K.2    Yamamoto, T.3    Kawamura, M.4    Sakoda, T.5    Fujioka, H.6    Matsuura, Y.7    Takai, Y.8
  • 43
    • 0027183541 scopus 로고
    • The PH domain, a common piece in the structural patchwork of signalling proteins
    • Musacchio, A., Gibson, T., Rice, P., Thompson, J. and Saraste, M. (1993) The PH domain, a common piece in the structural patchwork of signalling proteins. Trends Biochem Sci., 18, 343-348.
    • (1993) Trends Biochem Sci. , vol.18 , pp. 343-348
    • Musacchio, A.1    Gibson, T.2    Rice, P.3    Thompson, J.4    Saraste, M.5
  • 44
    • 0028829555 scopus 로고
    • A downstream target of RHO1 small GTP-binding protein is PKC1, a homolog of protein kinase C, which leads to activation of the MAP kinase cascade in Saccharomyces cerevisiae
    • Nonaka, H., Tanaka, K., Hirano, H., Fujiwara, T., Kohno, H., Umikawa, M., Mino, A. and Takai, Y (1995) A downstream target of RHO1 small GTP-binding protein is PKC1, a homolog of protein kinase C, which leads to activation of the MAP kinase cascade in Saccharomyces cerevisiae. EMBO J., 14, 5931-5938.
    • (1995) EMBO J. , vol.14 , pp. 5931-5938
    • Nonaka, H.1    Tanaka, K.2    Hirano, H.3    Fujiwara, T.4    Kohno, H.5    Umikawa, M.6    Mino, A.7    Takai, Y.8
  • 46
    • 0028148453 scopus 로고
    • Interactions between the bud emergence proteins Bem1p and Bem2p and Rho-type GTPases in yeast
    • Peterson, J., Zheng, Y., Bender, L., Myers, A., Cerione, R. and Bender, A. (1994) Interactions between the bud emergence proteins Bem1p and Bem2p and Rho-type GTPases in yeast. J. Cell Biol , 127, 1395-1406.
    • (1994) J. Cell Biol , vol.127 , pp. 1395-1406
    • Peterson, J.1    Zheng, Y.2    Bender, L.3    Myers, A.4    Cerione, R.5    Bender, A.6
  • 47
    • 0024599698 scopus 로고
    • Dominant yeast and mammalian RAS mutants that interfere with the CDC25-dependent activation of wild-type RAS in Saccharomyces cerevisiae
    • Powers, S., O'Neill, K and Wigler, M (1989) Dominant yeast and mammalian RAS mutants that interfere with the CDC25-dependent activation of wild-type RAS in Saccharomyces cerevisiae Mol. Cell. Biol., 9, 390-395
    • (1989) Mol. Cell. Biol. , vol.9 , pp. 390-395
    • Powers, S.1    O'Neill, K.2    Wigler, M.3
  • 48
    • 0026713293 scopus 로고
    • The small GTP-binding proteins in the cytosol of insulin-secreting cells are complexed to GDP dissociation inhibitor proteins
    • Regazzi, R., Kikuchi, A , Takai, Y. and Wollheim, C.B. (1992) The small GTP-binding proteins in the cytosol of insulin-secreting cells are complexed to GDP dissociation inhibitor proteins. J. Biol Chem., 267, 17512-17519
    • (1992) J. Biol Chem. , vol.267 , pp. 17512-17519
    • Regazzi, R.1    Kikuchi, A.2    Takai, Y.3    Wollheim, C.B.4
  • 49
    • 0024393426 scopus 로고
    • The N-terminal region of proto-dbl down regulates its transforming activity
    • Ron, D., Graziani, G., Aaronson, S.A and Eva, A. (1989) The N-terminal region of proto-dbl down regulates its transforming activity Oncogene, 4, 1067-1072.
    • (1989) Oncogene , vol.4 , pp. 1067-1072
    • Ron, D.1    Graziani, G.2    Aaronson, S.A.3    Eva, A.4
  • 50
    • 0023666149 scopus 로고
    • KAR1, a gene required for function of both intranuclear and extranuclear microtubules in yeast
    • Rose, M D. and Fink, G R. (1987) KAR1, a gene required for function of both intranuclear and extranuclear microtubules in yeast. Cell, 48, 1047-1060.
    • (1987) Cell , vol.48 , pp. 1047-1060
    • Rose, M.D.1    Fink, G.R.2
  • 52
    • 0027237511 scopus 로고
    • Ly-GDI, a GDP-dissociation inhibitor of the RhoA GTP-binding protein, is expressed preferentially in lymphocytes
    • Scherle, P., Behrens, T. and Staudt, L.M (1993) Ly-GDI, a GDP-dissociation inhibitor of the RhoA GTP-binding protein, is expressed preferentially in lymphocytes. Proc. Natl Acad. Sci. USA, 90, 7568-7572
    • (1993) Proc. Natl Acad. Sci. USA , vol.90 , pp. 7568-7572
    • Scherle, P.1    Behrens, T.2    Staudt, L.M.3
  • 54
    • 0024669291 scopus 로고
    • A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae
    • Sikorski, R S and Hieter, P. (1989) A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae. Genetics, 122, 19-27.
    • (1989) Genetics , vol.122 , pp. 19-27
    • Sikorski, R.S.1    Hieter, P.2
  • 56
    • 0027972531 scopus 로고
    • Novel human oncogene lbc detected by transfection with distinct homology regions to signal transduction products
    • Toksoz, D. and Williams, D.A. (1994) Novel human oncogene lbc detected by transfection with distinct homology regions to signal transduction products. Oncogene, 9, 621-628
    • (1994) Oncogene , vol.9 , pp. 621-628
    • Toksoz, D.1    Williams, D.A.2
  • 57
    • 0028246440 scopus 로고
    • Binding of G protein beta gamma-subunits to pleckstrin homology domains
    • Touhara, K., Inglese, J., Pitcher, J.A., Shaw, G. and Lefkowitz, R.J. (1994) Binding of G protein beta gamma-subunits to pleckstrin homology domains. J. Biol. Chem., 269, 10217-10220.
    • (1994) J. Biol. Chem. , vol.269 , pp. 10217-10220
    • Touhara, K.1    Inglese, J.2    Pitcher, J.A.3    Shaw, G.4    Lefkowitz, R.J.5
  • 58
    • 0025295180 scopus 로고
    • Purification and characterization from bovine brain cytosol of a novel regulatory protein inhibiting the dissociation of GDP from and the subsequent binding of GTP to rhoB p20, a ras p21-like GTP-binding protein
    • Ueda, T., Kikuchi, A., Ohga, N., Yamamoto, J and Takai, Y. (1990) Purification and characterization from bovine brain cytosol of a novel regulatory protein inhibiting the dissociation of GDP from and the subsequent binding of GTP to rhoB p20, a ras p21-like GTP-binding protein. J. Biol. Chem., 265, 9373-9380
    • (1990) J. Biol. Chem. , vol.265 , pp. 9373-9380
    • Ueda, T.1    Kikuchi, A.2    Ohga, N.3    Yamamoto, J.4    Takai, Y.5
  • 59
    • 0027250250 scopus 로고
    • Mammalian Ras interacts directly with the serine/threonine kinase Raf
    • Vojtek, A.B., Hollenberg, S.M. and Cooper, J.A. (1993) Mammalian Ras interacts directly with the serine/threonine kinase Raf. Cell, 74, 205-214.
    • (1993) Cell , vol.74 , pp. 205-214
    • Vojtek, A.B.1    Hollenberg, S.M.2    Cooper, J.A.3
  • 60
    • 0029155976 scopus 로고
    • Expression cloning of lfc, a novel oncogene with structural similarities to guanine nucleotide exchange factors and to the regulatory region of protein kinase C
    • Whitehead, I., Kirk, H., Tognon, C., Trigo-Gonzalez, G. and Kay, R. (1995) Expression cloning of lfc, a novel oncogene with structural similarities to guanine nucleotide exchange factors and to the regulatory region of protein kinase C. J. Biol. Chem., 270, 18388-18395.
    • (1995) J. Biol. Chem. , vol.270 , pp. 18388-18395
    • Whitehead, I.1    Kirk, H.2    Tognon, C.3    Trigo-Gonzalez, G.4    Kay, R.5
  • 61
    • 0028239341 scopus 로고
    • The Dbl oncogene product as a GDP/GTP exchange protein for the Rho family: Its properties in comparison with those of Smg GDS
    • Yaku, H., Sasaki, T. and Takai, Y. (1994) The Dbl oncogene product as a GDP/GTP exchange protein for the Rho family: its properties in comparison with those of Smg GDS. Biochem Biophys. Res. Commun., 198, 811-817.
    • (1994) Biochem Biophys. Res. Commun. , vol.198 , pp. 811-817
    • Yaku, H.1    Sasaki, T.2    Takai, Y.3
  • 62
    • 0025043199 scopus 로고
    • Purification and characterization from bovine brain cytosol of proteins that regulate the GDP/GTP exchange reaction of smg p21s, ras p21-like GTP-binding proteins
    • Yamamoto, T., Kaibuchi, K., Mizuno, T., Hiroyoshi, M., Shirataki, H. and Takai, Y (1990) Purification and characterization from bovine brain cytosol of proteins that regulate the GDP/GTP exchange reaction of smg p21s, ras p21-like GTP-binding proteins. J Biol. Chem., 265, 16626-16634.
    • (1990) J Biol. Chem. , vol.265 , pp. 16626-16634
    • Yamamoto, T.1    Kaibuchi, K.2    Mizuno, T.3    Hiroyoshi, M.4    Shirataki, H.5    Takai, Y.6
  • 63
    • 0028228614 scopus 로고
    • Growth site localization of Rho1 small GTP-binding protein and its involvement in bud formation in Saccharomyces cerevisiae
    • Yamochi, W., Tanaka, K., Nonaka, H., Maeda, A., Musha, T and Takai, Y. (1994) Growth site localization of Rho1 small GTP-binding protein and its involvement in bud formation in Saccharomyces cerevisiae J Cell Biol., 125, 1077-1093.
    • (1994) J Cell Biol. , vol.125 , pp. 1077-1093
    • Yamochi, W.1    Tanaka, K.2    Nonaka, H.3    Maeda, A.4    Musha, T.5    Takai, Y.6
  • 64
    • 0028023358 scopus 로고
    • Control of the yeast budsite assembly GTPase Cdc42. Catalysis of guanine nucleotide exchange by Cdc24 and stimulation of GTPase activity by Bem3
    • Zheng, Y., Cerione, R. and Bender, A. (1994) Control of the yeast budsite assembly GTPase Cdc42. Catalysis of guanine nucleotide exchange by Cdc24 and stimulation of GTPase activity by Bem3. J. Biol. Chem., 269, 2369-2372.
    • (1994) J. Biol. Chem. , vol.269 , pp. 2369-2372
    • Zheng, Y.1    Cerione, R.2    Bender, A.3
  • 65
    • 0028955710 scopus 로고
    • Interactions among proteins involved in bud-site selection and bud-site assembly in Saccharomyces cerevisiae
    • Zheng, Y., Bender, A. and Cerione, R.A. (1995a) Interactions among proteins involved in bud-site selection and bud-site assembly in Saccharomyces cerevisiae J. Biol. Chem., 270, 626-630.
    • (1995) J. Biol. Chem. , vol.270 , pp. 626-630
    • Zheng, Y.1    Bender, A.2    Cerione, R.A.3
  • 66
    • 0028967665 scopus 로고
    • Direct involvement of the small GTP-binding protein Rho in lbc oncogene function
    • Zheng, Y., Olson, M.F., Hall, A., Cerione, R.A. and Toksoz, D. (1995b) Direct involvement of the small GTP-binding protein Rho in lbc oncogene function. J. Biol. Chem., 270, 9031-9034.
    • (1995) J. Biol. Chem. , vol.270 , pp. 9031-9034
    • Zheng, Y.1    Olson, M.F.2    Hall, A.3    Cerione, R.A.4    Toksoz, D.5


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