Characterization of the 5′ flanking region of the rat D3 dopamine receptor gene

Journal of Neurochemistry

Volumn 76, Issue 6, 2001, Pages 1736-1744

  D'Souza, Ursula M ^a,c   Wang, Wei ^a,b   Gao, Da Qing ^a,d   Kanda, Seiji ^a,e   Lee, Gwang ^a   Junn, Eunsung ^a   Hwang, Cheol Kyu ^a,f   Jose, Pedro A ^b   Maral Mouradian, M ^a  

^a NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE   (United States)

^b GEORGETOWN UNIVERSITY   (United States)

^c KING'S COLLEGE LONDON   (United Kingdom)

^d UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^e NARA MEDICAL UNIVERSITY   (Japan)

^f UNIVERSITY OF MINNESOTA   (United States)

Author keywords

5 Flanking region; D3 gene; Dopamine receptor gene; Promoter region; Transcription regulation

Indexed keywords

DOPAMINE 3 RECEPTOR; COMPLEMENTARY DNA; DNA BINDING PROTEIN; DOPAMINE 2 RECEPTOR; DRD3 PROTEIN, HUMAN; DRD3 PROTEIN, RAT;

5' UNTRANSLATED REGION; ANIMAL CELL; ARTICLE; CONSENSUS SEQUENCE; CONTROLLED STUDY; DNA BASE COMPOSITION; DNA FLANKING REGION; EXON; GENE ISOLATION; GENE LOCATION; GENE SEQUENCE; GENETIC ANALYSIS; GENETIC TRANSCRIPTION; GENOME; HUMAN; HUMAN CELL; INTRON; NONHUMAN; PRIORITY JOURNAL; RAT; SILENCER GENE; TRANSCRIPTION INITIATION; ANIMAL; BINDING SITE; CELL CULTURE; CELL STRAIN COS1; CERCOPITHECUS; CHROMOSOME WALKING; CODON; COMPARATIVE STUDY; GENE DELETION; GENETICS; METABOLISM; MOLECULAR CLONING; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; OLFACTORY BULB; PROMOTER REGION; REPORTER GENE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ANIMALIA;

5' UNTRANSLATED REGIONS; ANIMALS; BASE COMPOSITION; BASE SEQUENCE; BINDING SITES; CERCOPITHECUS AETHIOPS; CHROMOSOME WALKING; CLONING, MOLECULAR; CODON; COS CELLS; DNA, COMPLEMENTARY; DNA-BINDING PROTEINS; EXONS; GENES, REPORTER; HUMANS; INTRONS; MOLECULAR SEQUENCE DATA; OLFACTORY BULB; PROMOTER REGIONS (GENETICS); RATS; RECEPTORS, DOPAMINE D2; RECEPTORS, DOPAMINE D3; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SEQUENCE DELETION; TRANSCRIPTION, GENETIC; TUMOR CELLS, CULTURED;

EID: 0034745482     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.2001.00155.x     Document Type: Article

References (44)

1. Linkage, association and mutational analysis of the dopamine D3 receptor gene in schizophrenia
2. The human dopamine D5 receptor gene: Cloning and characterization of the 5′-flanking and promoter region
3. Localization of dopamine D3 receptor mRNA in the rat brain using in situ hybridization histochemistry: Comparison with dopamine D2 receptor mRNA
4. Association between schizophrenia and homozygosity at the dopamine D3 receptor gene
5. Antipsychotic regulation of dopamine D1, D2 and D3 receptor mRNA
6. Phenotypical characterization of neurons expressing the dopamine D3 receptor in the rat brain
7. A novel short isoform of the D3 dopamine receptor generated by alternative splicing in the third cytoplasmic loop
8. Molecular cloning and characterization of the mouse dopamine D3 receptor gene: An additional intron and an mRNA variant
9. Expression of the D2 subfamily of dopamine receptor genes in kidney
10. Gene cloning of human dopaminergic D3 receptor and identification of its chromosome
11. Shorter variants of the D3 dopamine receptor produced through various patterns of alternative splicing
12. Dopamine D3 receptor gene: Organization, transcript variants, and polymorphism associated with schizophrenia
13. Mesolimbic dopamine D3 receptors and use of antipsychotics in patients with schizophrenia
14. Cloning and characterization of the 5′-flanking region of the human dopamine D4 receptor gene
15. Differential visualization of dopamine D2 and D3 receptor sites in rat brain. A Comparative study using in situ hybridization histochemistry and ligand binding autoradiography
16. 3 receptor as a useful polymorphism for investigating psychiatric disorders
17. Chromosomal localization of the human D3 dopamine receptor gene
18. 1A dopamine receptor gene
19. Characterization of [3H]quinpirole binding to D2-like dopamine receptors in rat brain
20. Human D3 dopamine receptor in the medulloblastoma TE671 cell line: Cross-talk between D1 and D3 receptors
21. Identification, characterization, and localization of the dopamine D3 receptor in rat brain using 7-[3H]hydroxy-N,N-di-n-propyl-2-aminotetralin
22. Proposed schizophrenia-related gene polymorphism: Expression of the Ser9Gly mutant human dopamine D3 receptor with the Semliki Forest virus system
23. Relationship between homozygosity at the dopamine D3 receptor gene and schizophrenia
24. Characterization of the 5′ flanking region of the human D1A dopamine receptor gene
25. Analysis of the promoter region of the rat D2 dopamine receptor gene
26. A catalogue of splice junction sequences
27. Expression of the D3 dopamine receptor gene and a novel variant transcript generated by alternative splicing in human peripheral blood lymphocytes
28. Organization and expression of the rat D2A receptor gene: Identification of alternative transcripts and a variant donor splice site
29. Roles of TATA and initiator elements in determining the start site location and direction of RNA polymerase II transcription
30. Structural organization of the murine D3 dopamine receptor gene
31. Dopamine D3 receptor is decreased and D2 receptor is elevated in the striatum of Parkinson's disease
32. Selective loss of dopamine D3-type receptor mRNA expression in parietal and motor cortices of patients with chronic schizophrenia
33. Up-regulation of D3 dopamine receptor mRNA in the nucleus accumbens of human cocaine fatalities
34. The 'initiator' as a transcription control element
35. Alternative transcripts of the rat and human dopamine D3 receptor
36. Molecular cloning and characterization of a novel dopamine receptor (D3) as a target for neuroleptics
37. Adaptive increase in D3 dopamine receptors in the brain reward circuits of human cocaine fatalities
38. New insights into dopamine receptors in the central nervous system
39. Characterization of the human cell line TE671
40. Transcription of the rat dopamine-D2-receptor gene from two promoters
41. Bioamine receptors: Evolutionary and functional variations of a structural leitmotiv
42. Up-regulation of D3 dopamine receptor mRNA by neuroleptics
43. Characterization of gene organization and promoter region of the rat dopamine D1 receptor gene