Which craft is best in bioinformatics?

Computers and Chemistry

Volumn 25, Issue 4, 2001, Pages 329-339

  Attwood, T K ^a   Miller, C J ^a  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

Artificial intelligence; Biological complexity; Database; Genome; Knowledge representation; Ontology

Indexed keywords

COMPUTER SIMULATION; DATABASE SYSTEMS; GENETIC ENGINEERING; KNOWLEDGE REPRESENTATION; PROTEINS;

BIOLOGICAL COMPLEXITY; ONTOLOGY;

BIOLOGY;

PROTEIN;

AMINO ACID SEQUENCE; ARTIFICIAL INTELLIGENCE; BIOLOGY; CHEMICAL STRUCTURE; CHEMISTRY; FACTUAL DATABASE; GENOME; HUMAN; METHODOLOGY; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; PROTEIN FOLDING; PROTEIN SECONDARY STRUCTURE; REVIEW; SEQUENCE ANALYSIS; SEQUENCE HOMOLOGY;

AMINO ACID SEQUENCE; ARTIFICIAL INTELLIGENCE; BASE SEQUENCE; COMPUTATIONAL BIOLOGY; DATABASES, FACTUAL; GENOME, HUMAN; HUMANS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PROTEIN FOLDING; PROTEIN STRUCTURE, SECONDARY; PROTEINS; SEQUENCE ANALYSIS, PROTEIN; SEQUENCE HOMOLOGY, NUCLEIC ACID;

EID: 0034742445     PISSN: 00978485     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0097-8485(01)00069-9     Document Type: Article

References (39)

1. Basic local alignment search tool
2. The InterPro database, an integrated documentation resource for protein families, domains and functional sites
3. Gene ontology: Tool for the unification of biology
4. The Babel of bioinformatics
5. PRINTS-S: The database formerly known as PRINTS
6. The Pfam protein families database
7. Go hunting in sequence databases but watch out for the traps
8. Powers and pitfalls in sequence analysis: The 70% hurdle
9. Genome analysis: Errors in genome annotation
10. Protein function in the post-genomic era
11. Distinguishing homologous from analogous proteins
12. Homology - A personal view on some of the problems
13. Sources of systematic error in functional annotation of genomes: Domain rearrangement, non-orthologous gene displacement and operon disruption
14. Who's your neighbour? New computational approaches for functional genomics
15. Can sequence determine function?
16. Orthologs, paralogs and genome comparisons
17. SELEX and the evolution of genomes
18. Organising and computing metabolic pathway data in terms of binary relations
19. Cyc: A midterm report
20. Increased coverage of protein families with the blocks database servers
21. The PROSITE database, its status in 1999
22. Evolution and tinkering
23. What we do not know about sequence analysis and sequence databases
24. An ontology for biological function based on molecular interactions
25. Unreliability of the Chou-Fasman parameters in predicting protein secondary structure
26. Annotating eukaryotic genomes
27. Rapid and sensitive protein similarity searches
28. The role of the genome project in determining gene function: Insights from model organisms
29. Whither genomics?
30. From fold recognition to homology modeling: An analysis of protein modeling challenges at different levels of prediction complexity
31. Combination of threading potentials and sequence profiles improves fold recognition
32. Homology in proteins and nucleic acids: A terminology muddle and a way out of it
33. Genome annotation assessment in Drosophila melanogaster
34. Sisyphus and prediction of protein structure
35. Progress in protein structure prediction: Assessment of CASP3
36. Late night thoughts on the sequence annotation problem
37. Structure-based assignment of the biochemical function of a hypothetical protein: A test case of structural genomics