Synthesis, 5-HT1A and 5-HT2A receptor activity of new 1-phenylpiperazinylpropyl derivatives with arylalkyl substituents in position 7 of purine-2,6-Dione

Polish Journal of Pharmacology

Volumn 53, Issue 4, 2001, Pages 359-368

  Chlon G ^a   Pawloski, M ^a   Duszynska B ^a   Szaro, A ^a   Tatarcztynska E ^a   Klodzinska A ^a   Chojnacka Wojcik E ^a  

^a INSTITUTE OF PHARMACOLOGY   (Poland)

Author keywords

1 arylpiperazine; 5 HT1A receptor antagonists; Purine 2,6 diones; Structure activity relationship

Indexed keywords

1 PHENYLPIPERAZINYLPROPYL DERIVATIVE; 1,3 DIMETHYL 7 PHENYLMETHYL 8 [3 (4 PHENYL 1 PIPERAZINYL)PROPYLAMINO]PURINE 2,6 DIONE; 1,3 DIMETHYL 7 PHENYLPROPYL 8 [3 (4 PHENYL 1 PIPERAZINYL)PROPYLAMINO]PURINE 2,6 DIONE; 2 DIPROPYLAMINO 8 HYDROXYTETRALIN; LIGAND; N [2 [4 (2 METHOXYPHENYL) 1 PIPERAZINYL]ETHYL] N (2 PYRIDYL)CYCLOHEXANECARBOXAMIDE; PURINE 2,6 DIONE DERIVATIVE; PURINE DERIVATIVE; RESERPINE; SEROTONIN 1 AGONIST; SEROTONIN 1 ANTAGONIST; SEROTONIN 1 RECEPTOR; SEROTONIN 2 RECEPTOR; UNCLASSIFIED DRUG; PIPERAZINE DERIVATIVE; SEROTONIN 2A RECEPTOR; SEROTONIN ANTAGONIST; SEROTONIN RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BEHAVIOR; BODY TEMPERATURE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG STRUCTURE; DRUG SYNTHESIS; HYPOTHERMIA; IN VIVO STUDY; LIP; MALE; MOUSE; NONHUMAN; RAT; RECEPTOR AFFINITY; SYNDROME; ANIMAL; ANIMAL BEHAVIOR; BINDING COMPETITION; BRAIN CORTEX; CHEMISTRY; DRUG EFFECT; HIPPOCAMPUS; MASS SPECTROMETRY; METABOLISM; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; RADIOASSAY; STRUCTURE ACTIVITY RELATION; SYNTHESIS; WISTAR RAT;

ANIMALS; BEHAVIOR, ANIMAL; BINDING, COMPETITIVE; BODY TEMPERATURE; CEREBRAL CORTEX; HIPPOCAMPUS; LIGANDS; LIP; MAGNETIC RESONANCE SPECTROSCOPY; MALE; MASS SPECTROMETRY; MICE; PIPERAZINES; PURINES; RADIOLIGAND ASSAY; RATS; RATS, WISTAR; RECEPTOR, SEROTONIN, 5-HT2A; RECEPTORS, SEROTONIN; RECEPTORS, SEROTONIN, 5-HT1; RESERPINE; SEROTONIN ANTAGONISTS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0034740049     PISSN: 12306002     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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