New 9- or 10-arylpiperazinoalkyl substituted pyrimido- or diazepino[2,1- f]purines with partial or full 5-HT(1A) agonistic activity

European Journal of Medicinal Chemistry

Volumn 34, Issue 2, 1999, Pages 167-175

  Pawlowski, MacIej ^a   Katlabi, Jacek ^a   Drabczynska, Anna ^a   Duszynska, Beata ^b   Charakchieva Minol, Sijka ^b   Deren Wesolek, Anna ^b   Tatarczynska, Ewa ^b   Chojnacka Wójcik, Ewa ^b   Mokrosz, Maria J ^b   Bojarski, Andrzej J ^b  

^a JAGIELLONIAN UNIVERSITY MEDICAL COLLEGE   (Poland)

^b INSTITUTE OF PHARMACOLOGY   (Poland)

Author keywords

1 arylpiperazine; 5 HT(1A) agonists; Diazepinopurines; Pyrimidopurines

Indexed keywords

1,3 DIMETHYL 9 [3 [4 (2' METHOXYPHENYL) 1 PIPERAZINYL]PROPYL] 2,4,8 TRIOXO 1,3 DIHYDRO 9H PYRIMIDO[2,1 F]PURINE; 1,3 DIMETHYL 9 [3 [4 (2' METHYOXYPHENYL) 1 PIPERAZINYL]PROPYL] 2,4 DIOXO 1,3,6,7,8,9 HEXAHYDROPYRIMIDO[2,1 F]PURINE; PURINE DERIVATIVE; SEROTONIN 1A RECEPTOR; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG RECEPTOR BINDING; DRUG SYNTHESIS; HYPOTHERMIA; INTRAPERITONEAL DRUG ADMINISTRATION; LIPOPHILICITY; MOUSE; NONHUMAN; RAT; RECEPTOR AFFINITY;

EID: 0032742726     PISSN: 02235234     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0223-5234(99)80050-6     Document Type: Article

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