Loss of calpain 3 proteolytic activity leads to muscular dystrophy and to apoptosis-associated IκBα/nuclear factor κB pathway perturbation in mice

Journal of Cell Biology

Volumn 151, Issue 7, 2000, Pages 1583-1590

  Richard, Isabelle ^a   Roudaut, Carinne ^a   Marchand, Sylvie ^a   Baghdiguian, Stephen ^b   Herasse, Muriel ^a   Stockholm, Daniel ^a   Ono, Yasuko ^d   Suel, Laurence ^a   Bourg, Nathalie ^a   Sorimachi, Hiroyuki ^d   Lefranc, Gérard ^c   Fardeau, Michel ^e   Sébille, Alain ^f   Beckmann, Jacques S ^a,g,h  

^a GÉNÉTHON   (France)

^b CNRS   (France)

^c CNRS and University Montpellier II   (France)

^d UNIVERSITY OF TOKYO   (Japan)

^e PITIÉ SALPÊTRIÈRE HOSPITAL   (France)

^f SORBONNE UNIVERSITÉ   (France)

^g CENTRE NATIONAL DE GÉNOTYPAGE   (France)

^h WEIZMANN INSTITUTE OF SCIENCE   (Israel)

Author keywords

Apoptosis; Calpain; I B NF B pathway; Knockout mice; Muscular dystrophies

Indexed keywords

CALPAIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN;

ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; GENE TARGETING; KNOCKOUT MOUSE; MOUSE; MUSCULAR DYSTROPHY; MYOPATHY; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; RNA ANALYSIS; SKELETAL MUSCLE;

ANIMALS; APOPTOSIS; CALPAIN; CREATINE KINASE; CROSSES, GENETIC; DNA-BINDING PROTEINS; EVANS BLUE; FEMALE; FERTILITY; GENE DELETION; GENE TARGETING; GENOTYPE; I-KAPPA B PROTEINS; MALE; MICE; MICE, KNOCKOUT; MUSCLE FIBERS; MUSCLE, SKELETAL; MUSCULAR DYSTROPHIES; NF-KAPPA B; PHENOTYPE; RNA, MESSENGER; SARCOLEMMA; SIGNAL TRANSDUCTION;

EID: 0034739841     PISSN: 00219525     EISSN: None     Source Type: Journal    
DOI: 10.1083/jcb.151.7.1583     Document Type: Article

References (25)

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