Expression and functional characteristics of calpain 3 isoforms generated through tissue-specific transcriptional and posttranscriptional events

Molecular and Cellular Biology

Volumn 19, Issue 6, 1999, Pages 4047-4055

  Herasse, Muriel ^a   Ono, Yasuko ^b   Fougerousse, Françoise ^a   Kimura, Ei Ichi ^b   Stockholm, Daniel ^a   Beley, Cyriaque ^a   Montarras, Didier ^c   Pinset, Christian ^c   Sorimachi, Hiroyuki ^b   Suzuki, Koichi ^b   Beckmann, Jacques S ^a   Richard, Isabelle ^a  

^a GÉNÉTHON   (France)

^b UNIVERSITY OF TOKYO   (Japan)

^c INSTITUT PASTEUR   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CALPAIN; CONNECTIN; FODRIN;

ALTERNATIVE RNA SPLICING; ANIMAL TISSUE; ARTICLE; CALCIUM BINDING; EMBRYO; EXON; IN SITU HYBRIDIZATION; INTRON; LIMB GIRDLE MUSCULAR DYSTROPHY; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN ANALYSIS; PROTEIN EXPRESSION; TRANSCRIPTION REGULATION;

EID: 0033050067     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.19.6.4047     Document Type: Article

References (39)

1. Bucher, P. 1989. Weight matrix descriptions of four eukaryotic RNA polymerase II promoter elements derived from 502 unrelated promoter sequences. J. Mol. Biol. 212:563-578.
2. Chu, G., H. Hayakawa, and P. Berg. 1987. Electroporation for the efficient transfection of mammalian cells with DNA. Nucleic Acids Res. 15:1311-1326.
3. David, L. L., and T. R. Shearer. 1986. Purification of calpain II from rat lens and determination of endogenous substrates. Exp. Eye Res. 42:227-238.
4. Fardeau, M., D. Hillaire, C. Mignard, N. Feingold, D. Mignard, B. de Ubeda, H. Collin, F. M. S. Tomé, I. Richard, and J. S. Beckmann. 1996. Juvenile limb-girdle muscular dystrophy: clinical, histopathological, and genetic data from a small community living in the Reunion Island. Brain 119:295-308.
5. Fougerousse, F., M. Durand, L. Suel, O. Pourquié, A.-L. Delezoide, N. Roméro, M. Abitbol, and J. S. Beckmann. 1998. Expression of genes (CAPN3, SGCA, SGCB and TTN) involved in progressive muscular dystrophies during early human development. Genomics 48:145-156.
6. Fougerousse, F., P. Bullen, M. Herasse, S. Lindsay, I. Richard, S. Lee, L. Suel, A. McMahon, D. Durand, S. Robson, D. Wilson, M. Abitbol, J. S. Beckmann, and T. Strachan. Human-mouse differences in the expression patterns of disease genes and developmental control genes during early development. Submitted for publication.
7. Harris, A. S., D. E. Croall, and J. S. Morrow. 1988. The calmodulin-binding site in alpha-fodrin is near the calcium-dependent protease-I cleavage site. J. Biol. Chem. 263:15754-15761.
8. Heid, C. A., J. Steven, K. J. Livak, and P. M. Williams. 1996. Real time quantitative PCR. Genome Res. 6:986-994.
9. Heinemeyer, T., E. Wingender, I. Reuter, H. Hermjakob, O. Kel, E. Ignatieva, E. Ananko, O. Podkolodnaya, F. Kolpakov, N. Podkolodny, and N. Kolchanov. 1998. Databases on transcriptional regulation: TRANSFAC, TRRD, and COMPEL. Nucleic Acids Res. 26:364-370.
10. Jackson, I. J. 1991. A reappraisal of non-consensus mRNA splice sites. Nucleic Acids Res. 19:3795-3798.
11. Kinbara, K., H. Sorimachi, S. Ishiura, and K. Suzuki. 1997. Muscle-specific calpain, p94, interacts with the extreme C-terminal region of connectin, a unique region flanked by two immunoglobulin C2 motifs. Arch. Biochem. Biophys. 342:99-107.
12. Kinbara, K., S. Ishiura, S. Tomioka, H. Sorimachi, S. Y. Jeong, S. Amano, H. Kawasaki, B. Kolmerer, S. Kimura, S. Labeit, and K. Suzuki. 1998. Purification of native p94, a muscle-specific calpain, and characterization of its autolysis. Biochem. J. 335:589-596.
13. Kolmerer, B., N. Olivieri, C. C. Witt, B. G. Herrmann, and S. Labeit. 1996. Genomic organization of M line titin and its tissue-specific expression in two distinct isoforms. J. Mol. Biol. 256:556-563.
14. Kozak, M. 1986. Point mutations define a sequence flanking the AUG initiator codon that modulates translation by eukaryotic ribosomes. Cell 44:283-292.
15. Labeit, S., and B. Kolmerer. 1995. Titins: giant proteins in charge of muscle ultrastructure and elasticity. Science 270:293-296.
16. Lee, H.-J., H. Sorimachi, S.-Y. Jeong, S. Ishiura, and K. Suzuki. 1998. Molecular cloning and characterization of a novel tissue-specific calpain predominantly expressed in the digestive tract. Biol. Chem. 379:175-183.
17. Ma, H., C. Fukiage, M. Azuma, and T. R. Shearer. 1998. Cloning and expression of mRNA for calpain Lp82 from rat lens: splice variant of p94. Investig. Ophthalmol. Vis. Sci. 39:454-461.
18. Ma, H., M. Shin, I. Hata, C. Fukiage, M. Azuma, and T. R. Shearer. 1998. Protein for Lp82 calpain is expressed and enzymatically active in young rat lens. Exp. Eye Res. 67:221-229.
19. McMahon, A. S., and R. T. Moon. 1987. Structure and evolution of a non-erythroid spevtrin, human alpha-fodrin. Biochem. Soc. Trans. 15:804-807.
20. Ono, Y., H. Shimada, H. Sorimachi, I. Richard, T. C. Saido, J. S. Beckmann, S. Ishiura, and K. Suzuki. 1998. Functional defects of a muscle-specific calpain, p94, caused by mutations associated with limb-girdle muscular dystrophy type 2A. J. Biol. Chem. 273:17073-17078.
21. Pestridge, D. S. 1995. Predicting PolII promoter sequences using transcription factor binding sites. J. Mol. Biol. 249:923-932.
22. Piatigorsky, J. 1994. Puzzle of crystallin diversity in eye lenses. Dev. Dyn. 196:267-272.
23. Quandt, K., K. Frech, H. Karas, E. Wingender, and T. Werner. 1995. MatInd and MatInspector - new fast and versatile tools for detection of consensus matches in nucleotide sequence data. Nucleic Acids Res. 23:4878-4884.
24. Richard, I., O. Broux, V. Allamand, F. Fougerousse, N. Chiannilkulchai, N. Bourg, L. Brenguier, C. Devaud, P. Pasturaud, C. Roudaut, D. Hillaire, M.-R. Passos-Bueno, M. Zatz, J. A. Tischfield, M. Fardeau, C. E. Jackson, D. Cohen, and J. S. Beckmann. 1995. Mutations in the proteolytic enzyme calpain 3 cause limb-girdle muscular dystrophy type 2A. Cell 81:27-40.
25. Richard, I., and J. S. Beckmann. 1996. Molecular cloning of mouse canp3, the gene associated with limb-girdle muscular dystrophy 2A in human. Mamm. Genome 7:377-379.
26. Saldo, T., H. Sorimachi, and K. Suzuki. 1994. Calpain: new perspectives in molecular diversity and physiological-pathological involvement. FASEB J. 8:814-822.
27. Saldo, T. C., M. Yokota, S. Nagao, I. Yamaura, E. Tani, T. Tsuchiya, K. Suzuki, and S. Kawashima. 1993. Spacial resolution of fodrin proteolysis in postischemic brain. J. Biol. Chem. 268:25239-25243.
28. Schiaffino, S., and G. Salviati. 1997. Molecular diversity of myofibrillar proteins: isoforms analysis at the protein and mRNA level. Methods Cell Biol. 52:349-369.
29. Sekido, R., K. Murai, J.-I. Funahashi, Y. Kamachi, A. Fujisawa-Sehara, Y.-I. Nabeshima, and H. Kondoh. 1994. The δ-crystallin enhancer-binding protein δEF1 is a repressor of E2-box-mediated gene activation. Mol. Cell. Biol. 14:5692-5700.
30. Shapiro, M. B., and P. Senapathy. 1987. RNA splice junctions of different classes of eukaryotes: sequence statistics and functional implications in gene expression. Nucleic Acids Res. 15:7155-7174.
31. Sorimachi, H., S. Imajoh-Ohmi, Y. Emori, H. Kawasaki, S. Ohno, Y. Minami, and K. Suzuki. 1989. Molecular cloning of a novel mammalian calcium-dependent protease distinct from both m- and mu-types. Specific expression of the mRNA in skeletal muscle. J. Biol. Chem. 264:20106-20111.
32. Sorimachi, H., N. Toyama-Sorimachi, T. C. Saldo, H. Kawasaki, H. Sugita, M. Miyasaka, K. Arahata, S. Ishiura, and K. Suzuki. 1993. Muscle-specific calpain, p94. is degraded by autolysis immediately after translation, resulting in disappearance from muscle. J. Biol. Chem. 268:10593-10605.
33. 2+-binding domain. J. Biol. Chem. 268:19476-19482.
34. Sorimachi, H., K. Kimbara, S. Kimura, M. Takahashi, S. Ishiura, N. Sasagawa, N. Sorimachi, H. Shimada, K. Tagawa, K. Maruyama, and K. Suzuki. 1995. Muscle-specific calpain, p94, responsible for limb-girdle muscular dystrophy type 2A, associates with connectin through IS2, a p94-specific sequence. J. Biol. Chem. 270:31158-31162.
35. Sorimachi, H., S. Kimura, K. Kinbara, J. Kazama, M. Takahashi, H. Yajima, S. Ishiura, N. Sasagawa, I. Nonaka, H. Sugita, K. Maruyama, and K. Suzuki. 1996. Structure and physiological functions of ubiquitous and tissue-specific calpain species. Muscle-specific calpain, p94, interacts with connectin/titin. Adv. Biophys. 33:101-122.
36. Sorimachi, H., S. Ishiura, and K. Suzuki. 1997. Structure and physiological function of calpains. Biochem. J. 328:721-732.
37. Takebe, Y., M. Seiki, J.-I. Fujisawa, P. Hoy, K. Yokota, K.-I. Arai, M. Yoshida, and N. Aral. 1988. SRa promoter: an efficient and versatile mammalian cDNA expression system composed of the simian virus 40 early promoter and the R-U5 segment of human T-cell leukemia virus type 1 long terminal repeat. Mol. Cell. Biol. 8:466-472.
38. Theopold, U., M. Pinter, S. Daffre, Y. Tryselius, P. Friedrich, D. R. Nassel, and D. Hultmark. 1995. CalpA, a Drosophila calpain homolog specifically expressed in a small set of nerve, midgut, and blood cells. Mol. Cell. Biol. 15:824-834.
39. Wistow, G., and J. Piatigorsky. 1987. Recruitment of enzymes as lens structural proteins. Science 236:1554-1556.