-
1
-
-
0026138425
-
Synthetic polymers with intrinsic anticancer activity
-
SEYMOUR L. - Synthetic polymers with intrinsic anticancer activity. - J. Bioact. Compat. Polymers, 6, 178-216, 1991.
-
(1991)
J. Bioact. Compat. Polymers
, vol.6
, pp. 178-216
-
-
Seymour, L.1
-
2
-
-
0016622773
-
Structure and properties of pharmacologically active polymers
-
RINGSDORF H. -Structure and properties of pharmacologically active polymers. - J. Polym. Sci. Polymer Symp., 51, 135-53, 1975.
-
(1975)
J. Polym. Sci. Polymer Symp.
, vol.51
, pp. 135-153
-
-
Ringsdorf, H.1
-
3
-
-
0001491999
-
Polymeric antitumour agents on a molecular and cellular level
-
GROS L., RINGSDORF H. and SCHUPP H. - Polymeric antitumour agents on a molecular and cellular level. - Angew. Chemie Int. Ed. Eng., 20, 301-323, 1981.
-
(1981)
Angew. Chemie Int. Ed. Eng.
, vol.20
, pp. 301-323
-
-
Gros, L.1
Ringsdorf, H.2
Schupp, H.3
-
4
-
-
0026124772
-
The therapeutic values of poly(ethylene glycol)-modified proteins
-
NUCCI M.L., SHORR and ABUCHOWSKI A. - The therapeutic values of poly(ethylene glycol)-modified proteins. - Adv. Drug Delivery Rev., 6, 133-151, 1991.
-
(1991)
Adv. Drug Delivery Rev.
, vol.6
, pp. 133-151
-
-
Nucci, M.L.1
Shorr2
Abuchowski, A.3
-
5
-
-
0030047854
-
Polyethylene glycol modification : Relevance to improved methodology to tumour targeting
-
FRANCIS G.E., DELGADO C., FISHER D., MALIK F. and ARGRAWAL A.K. - Polyethylene glycol modification : relevance to improved methodology to tumour targeting. - J. Drug Targeting, 3, 321-340, 1996.
-
(1996)
J. Drug Targeting
, vol.3
, pp. 321-340
-
-
Francis, G.E.1
Delgado, C.2
Fisher, D.3
Malik, F.4
Argrawal, A.K.5
-
6
-
-
0026118760
-
SMANCS and polymer-conjugated macromolecular drugs : Advantages in cancer chemotherapy
-
MAEDA H. - SMANCS and polymer-conjugated macromolecular drugs : advantages in cancer chemotherapy. - Adv. Drug Del. Rev., 6, 181-202, 1991.
-
(1991)
Adv. Drug Del. Rev.
, vol.6
, pp. 181-202
-
-
Maeda, H.1
-
7
-
-
0002649813
-
Targeting chemotherapy of hepatocellular carcinoma : Arterial administration of SMANCS/ lipiodol
-
K. Okada and K.G. Ishak Eds., Springer Verlag, New York
-
KONNO T. and MAEDA H. - Targeting chemotherapy of hepatocellular carcinoma : arterial administration of SMANCS/ lipiodol. - In : Neoplasma of the Liver, K. Okada and K.G. Ishak Eds., Springer Verlag, New York, 1987, pp. 343-352.
-
(1987)
Neoplasma of the Liver
, pp. 343-352
-
-
Konno, T.1
Maeda, H.2
-
8
-
-
0011829793
-
A Phase II study of polyethylene glycol (PEG) conjugated L-asparaginase in patients with refractory acute leukæmias
-
KURTZBERG J., MOORE J. O., SCUDIERY D. and FRANKLIN N.J. - A Phase II study of polyethylene glycol (PEG) conjugated L-asparaginase in patients with refractory acute leukæmias. - Proc. Am. Soc. Cancer Res., 29, 213, 1988.
-
(1988)
Proc. Am. Soc. Cancer Res.
, vol.29
, pp. 213
-
-
Kurtzberg, J.1
Moore, J.O.2
Scudiery, D.3
Franklin, N.J.4
-
9
-
-
0001078556
-
Clinical Phase I trial (HPMA copolymer doxorubicin)
-
VASEY P.A., DUNCAN R., KAYE S.B. and CASSIDY J. - Clinical Phase I trial (HPMA copolymer doxorubicin). - Eur. J. Cancer, 31A, S193, 1995.
-
(1995)
Eur. J. Cancer
, vol.31 A
-
-
Vasey, P.A.1
Duncan, R.2
Kaye, S.B.3
Cassidy, J.4
-
10
-
-
7444244112
-
Improved drug targeting : Polymer therapeutics
-
January
-
CHARLISH P.-Improved drug targeting : polymer therapeutics. - Pharmaprojects Magazine, January 1996, pp. 16-19.
-
(1996)
Pharmaprojects Magazine
, pp. 16-19
-
-
Charlish, P.1
-
11
-
-
0002405110
-
Soluble synthetic polymers as potential drug carriers
-
DUNCAN R. and KOPECEK J. - Soluble synthetic polymers as potential drug carriers. - Adv. Polymer Sci., 57, 51-101, 1984.
-
(1984)
Adv. Polymer Sci.
, vol.57
, pp. 51-101
-
-
Duncan, R.1
Kopecek, J.2
-
12
-
-
0026757191
-
Drug-polymer conjugates : Potential for improved chemotherapy
-
DUNCAN R.-Drug-polymer conjugates : potential for improved chemotherapy. - Anti-Cancer Drugs, 3, 175-210, 1992.
-
(1992)
Anti-Cancer Drugs
, vol.3
, pp. 175-210
-
-
Duncan, R.1
-
13
-
-
0027987791
-
Polymer conjugates: Pharmacokinetic considerations for design and development
-
DUNCAN R. and SPREAFICO F. - Polymer conjugates: pharmacokinetic considerations for design and development. - Clinical Pharmacokinetics, 27, 290-306, 1994.
-
(1994)
Clinical Pharmacokinetics
, vol.27
, pp. 290-306
-
-
Duncan, R.1
Spreafico, F.2
-
14
-
-
0024569433
-
The applications of drug-polymer conjugates in chemotherapy
-
F.H.D. Roerdink and A.M. Kroon Eds., Wiley and Sons Ltd., Chichester
-
HOES C.J.T. and FEIJEN J.- The applications of drug-polymer conjugates in chemotherapy.-In : Drug-Carrier Systems, F.H.D. Roerdink and A.M. Kroon Eds., Wiley and Sons Ltd., Chichester, 1989, pp. 57-109.
-
(1989)
Drug-Carrier Systems
, pp. 57-109
-
-
Hoes, C.J.T.1
Feijen, J.2
-
15
-
-
0024410772
-
Soluble macromolecular carriers for delivery of antitumour agents
-
SEZAKI H., TAKAKURA Y. and HASHIDA M. - Soluble macromolecular carriers for delivery of antitumour agents. - Adv. Drug Del. Rev., 3, 247-66, 1989.
-
(1989)
Adv. Drug Del. Rev.
, vol.3
, pp. 247-266
-
-
Sezaki, H.1
Takakura, Y.2
Hashida, M.3
-
16
-
-
0000518632
-
Soluble polymers as targetable drug carriers
-
R.L. Juliano Ed., Springer Verlag, Berlin
-
KRINICK N.L. and KOPECEK J. - Soluble polymers as targetable drug carriers. - In : Targeted Drug Delivery, Handbook of Experimental Pharmacology, R.L. Juliano Ed., Springer Verlag, Berlin, 1991, pp.105-179.
-
(1991)
Targeted Drug Delivery, Handbook of Experimental Pharmacology
, pp. 105-179
-
-
Krinick, N.L.1
Kopecek, J.2
-
17
-
-
0346551010
-
Polymer conjugates with anticancer activity
-
PUTTNAM D. and KOPECEK J. - Polymer conjugates with anticancer activity. - Adv. Polym. Sci., 122, 55-123, 1995.
-
(1995)
Adv. Polym. Sci.
, vol.122
, pp. 55-123
-
-
Puttnam, D.1
Kopecek, J.2
-
18
-
-
0002401080
-
Chemotherapy of neoplastic diseases
-
J.G. Hardman and L.E. Limbird Eds., McGraw-Hill, New York
-
CALIBRESI P. and CHABNER B.A. - Chemotherapy of neoplastic diseases. - In : The Pharmacological Basis of Therapeutics, J.G. Hardman and L.E. Limbird Eds., McGraw-Hill, New York, 1996, pp. 1225-1288.
-
(1996)
The Pharmacological Basis of Therapeutics
, pp. 1225-1288
-
-
Calibresi, P.1
Chabner, B.A.2
-
19
-
-
0029360757
-
Block copolymer micelles as long-circulating drug vehicles
-
KWON G.S. and KATAOKA K. - Block copolymer micelles as long-circulating drug vehicles. - Adv. Drug Del. Rev., 16, 295-309, 1995.
-
(1995)
Adv. Drug Del. Rev.
, vol.16
, pp. 295-309
-
-
Kwon, G.S.1
Kataoka, K.2
-
20
-
-
0027787746
-
Pharmacokinetics of high molecular weight agents
-
CASSIDY J., NEWELL D.R., WEDGE S.R. and CUMMINGS J. - Pharmacokinetics of high molecular weight agents. - Cancer Surveys, 17, 315-341, 1993.
-
(1993)
Cancer Surveys
, vol.17
, pp. 315-341
-
-
Cassidy, J.1
Newell, D.R.2
Wedge, S.R.3
Cummings, J.4
-
21
-
-
0026635281
-
Doxorubicin-loaded nanospheres bypass tumour cell multidrug resistance
-
CUVIER C., ROBLOT-TREUPEL L., MILLOT J.M., LIZARD G., CHEVILLARD S., MANFAIT M., COUVREUR P. and POUPON M.F. - Doxorubicin-loaded nanospheres bypass tumour cell multidrug resistance. - Biochemical Pharmacology, 44, 509-517, 1992.
-
(1992)
Biochemical Pharmacology
, vol.44
, pp. 509-517
-
-
Cuvier, C.1
Roblot-Treupel, L.2
Millot, J.M.3
Lizard, G.4
Chevillard, S.5
Manfait, M.6
Couvreur, P.7
Poupon, M.F.8
-
22
-
-
0022858683
-
A new concept for macromolecular therapeutics in cancer chemotherapy ; mechanism of tumoritropic accumulation of proteins and the antitumour agent SMANCS
-
MATSUMURA Y. and MAEDA H. - A new concept for macromolecular therapeutics in cancer chemotherapy ; mechanism of tumoritropic accumulation of proteins and the antitumour agent SMANCS. - Cancer Res., 6, 6387-6392, 1986.
-
(1986)
Cancer Res.
, vol.6
, pp. 6387-6392
-
-
Matsumura, Y.1
Maeda, H.2
-
23
-
-
0024839642
-
Tumoritropic and lymphotropic principles of macromolecular drugs
-
MAEDA H. and MATSUMURA Y. - Tumoritropic and lymphotropic principles of macromolecular drugs. - CRC Crit. Rev. Ther. Drug Carrier Sys., 6, 193-210, 1989.
-
(1989)
CRC Crit. Rev. Ther. Drug Carrier Sys.
, vol.6
, pp. 193-210
-
-
Maeda, H.1
Matsumura, Y.2
-
24
-
-
0026694788
-
Passive tumour targeting of soluble macromolecules and drug conjugates
-
SEYMOUR L.W. - Passive tumour targeting of soluble macromolecules and drug conjugates. - CRC Crit. Rev. Ther. Drug Carrier Sys., 9, 135-187 1992.
-
(1992)
CRC Crit. Rev. Ther. Drug Carrier Sys.
, vol.9
, pp. 135-187
-
-
Seymour, L.W.1
-
25
-
-
0021908189
-
Conjugation of poly(styrene-co-maleic acid) derivatives to the antitumour protein neocarzinostatin : Pronounced improvements in pharmacological properties
-
MAEDA H., UEDA M., MORINAGA T. and MATSUMOTO T. - Conjugation of poly(styrene-co-maleic acid) derivatives to the antitumour protein neocarzinostatin : pronounced improvements in pharmacological properties. - J. Med. Chem., 28, 455-461, 1985.
-
(1985)
J. Med. Chem.
, vol.28
, pp. 455-461
-
-
Maeda, H.1
Ueda, M.2
Morinaga, T.3
Matsumoto, T.4
-
26
-
-
0021349643
-
Use of oily contrast medium for selective drug targeting to tumour : Enhanced therapeutic effect and X-ray image
-
IWAI K., MAEDA H. and KONNO T. - Use of oily contrast medium for selective drug targeting to tumour : enhanced therapeutic effect and X-ray image. - Cancer Res., 44, 2114-2121, 1984.
-
(1984)
Cancer Res.
, vol.44
, pp. 2114-2121
-
-
Iwai, K.1
Maeda, H.2
Konno, T.3
-
27
-
-
0024508158
-
Activity of N-(2-hydroxypropyl)methacrylamide copolymers containing daunomycin against a rat tumour model
-
CASSIDY J., DUNCAN R., MORRISON G.J., STROHALM J., PLOCOVA D., KOPECEK J. and KAYE S.B. - Activity of N-(2-hydroxypropyl)methacrylamide copolymers containing daunomycin against a rat tumour model.-Biochem. Pharmacol., 38, 875-879, 1989.
-
(1989)
Biochem. Pharmacol.
, vol.38
, pp. 875-879
-
-
Cassidy, J.1
Duncan, R.2
Morrison, G.J.3
Strohalm, J.4
Plocova, D.5
Kopecek, J.6
Kaye, S.B.7
-
28
-
-
0028030559
-
Tumouritropism and anticancer efficacy of polymer-based doxorubicin prodrugs in the treatment of subcutaneous murine B16F10 melanoma
-
SEYMOUR L.W., ULBRICH K., STYGER P.S., BRERETON M., SUBR V., STROHALM J. and DUNCAN R. -Tumouritropism and anticancer efficacy of polymer-based doxorubicin prodrugs in the treatment of subcutaneous murine B16F10 melanoma. - Brit. J. Cancer, 70, 636-641, 1994.
-
(1994)
Brit. J. Cancer
, vol.70
, pp. 636-641
-
-
Seymour, L.W.1
Ulbrich, K.2
Styger, P.S.3
Brereton, M.4
Subr, V.5
Strohalm, J.6
Duncan, R.7
-
29
-
-
0029039418
-
Influence of molecular size on passive tumour-accumulation of soluble macromolecular drug carriers
-
SEYMOUR L.W., MIYAMOTO Y., BRERETON M., STYGER P.S., MAEDA H., ULBRICH K. and DUNCAN R. - Influence of molecular size on passive tumour-accumulation of soluble macromolecular drug carriers. - Eur. J. Cancer, 5, 766-770, 1995.
-
(1995)
Eur. J. Cancer
, vol.5
, pp. 766-770
-
-
Seymour, L.W.1
Miyamoto, Y.2
Brereton, M.3
Styger, P.S.4
Maeda, H.5
Ulbrich, K.6
Duncan, R.7
-
30
-
-
0029150245
-
Vascular permeability in a human tumour xenograft : Molecular size dependence and cutoff size
-
YUAN F., DELLIAN M., FUKUMURA D., LEUNIG M., BERK D.A., TORCHILIN V.P. and JAIN R.K. - Vascular permeability in a human tumour xenograft : molecular size dependence and cutoff size. - Cancer Res., 55, 3752-3756, 1995.
-
(1995)
Cancer Res.
, vol.55
, pp. 3752-3756
-
-
Yuan, F.1
Dellian, M.2
Fukumura, D.3
Leunig, M.4
Berk, D.A.5
Torchilin, V.P.6
Jain, R.K.7
-
31
-
-
0028304405
-
Microvascular permeability and interstitial penetration of sterically stabilised (stealth) liposomes in a human tumour xenograft
-
YUAN F., LEUNIG M., SHI KUN H., BERK D.A., PAPAHADJOPOULOS D. and JAIN R.K. - Microvascular permeability and interstitial penetration of sterically stabilised (stealth) liposomes in a human tumour xenograft. - Cancer Res., 54, 3352-2256, 1994.
-
(1994)
Cancer Res.
, vol.54
, pp. 3352-12256
-
-
Yuan, F.1
Leunig, M.2
Shi Kun, H.3
Berk, D.A.4
Papahadjopoulos, D.5
Jain, R.K.6
-
32
-
-
0027299899
-
Augmentation of tumour delivery of macromolecular drugs with reduced bone marrow delivery by elevating blood pressure
-
LI C.J., MIYAMOTO Y., KOJIMA Y. and MAEDA H. - Augmentation of tumour delivery of macromolecular drugs with reduced bone marrow delivery by elevating blood pressure. - Br. J. Cancer, 67, 975-980, 1993.
-
(1993)
Br. J. Cancer
, vol.67
, pp. 975-980
-
-
Li, C.J.1
Miyamoto, Y.2
Kojima, Y.3
Maeda, H.4
-
33
-
-
0022635574
-
N-(2-hydroxypropyl)-methacrylamide copolymers with pendant galactosamine residues. Fate after intravenous administration to rats
-
DUNCAN R., SEYMOUR L.C.W., SCARLETT L., LLOYD, J.B., REJMANOVA P. and KOPECEK J. - N-(2-hydroxypropyl)-methacrylamide copolymers with pendant galactosamine residues. Fate after intravenous administration to rats. - Biochim. Biophys. Acta, 880, 62-71, 1986.
-
(1986)
Biochim. Biophys. Acta
, vol.880
, pp. 62-71
-
-
Duncan, R.1
Seymour, L.C.W.2
Scarlett, L.3
Lloyd, J.B.4
Rejmanova, P.5
Kopecek, J.6
-
34
-
-
0026069645
-
Synthetic polymers conjugated to monoclonal antibodies : Vehicles for tumour-targeted drug delivery
-
SEYMOUR L.W., FLANAGAN P.A., AL-SHAMKHANI A., SUBR V., ULBRICH K., CASSIDY J.A. and DUNCAN R. - Synthetic polymers conjugated to monoclonal antibodies : vehicles for tumour-targeted drug delivery. - Sel. Cancer Therap., 7, 59-73, 1991.
-
(1991)
Sel. Cancer Therap.
, vol.7
, pp. 59-73
-
-
Seymour, L.W.1
Flanagan, P.A.2
Al-Shamkhani, A.3
Subr, V.4
Ulbrich, K.5
Cassidy, J.A.6
Duncan, R.7
-
35
-
-
0030551528
-
Polymeric conjugates of drugs and antibodies for site-specific delivery
-
ULBRICH K., STROHALM J., SUBR V., PLOCOVA D., DUNCAN R. and RIHOVA B. - Polymeric conjugates of drugs and antibodies for site-specific delivery. - Makromol. Symp., 103, 177-192, 1996.
-
(1996)
Makromol. Symp.
, vol.103
, pp. 177-192
-
-
Ulbrich, K.1
Strohalm, J.2
Subr, V.3
Plocova, D.4
Duncan, R.5
Rihova, B.6
-
36
-
-
0030042022
-
HPMA copolymer-anticancer drug OVTL16 antibody conjugates. 1. Influence of the method of synthesis on binding affinity to OVCAR-3 ovarian carcinoma cells in vitro
-
OMELYANENKO V., KOPECKOVA P., GENTRY C., SHIAH J-G. and KOPECEK J. - HPMA copolymer-anticancer drug OVTL16 antibody conjugates. 1. Influence of the method of synthesis on binding affinity to OVCAR-3 ovarian carcinoma cells in vitro. - J. Drug Targeting, 3, 357-374, 1996.
-
(1996)
J. Drug Targeting
, vol.3
, pp. 357-374
-
-
Omelyanenko, V.1
Kopeckova, P.2
Gentry, C.3
Shiah, J.-G.4
Kopecek, J.5
-
37
-
-
0021271357
-
Tyrosinamide residues enhance pinocytic capture of N-(2- Hydroxypropyl)methacrylamide copolymers
-
DUNCAN R., CABLE H.C., REJMANOVA P., KOPECEK J. and LLOYD J.B.-Tyrosinamide residues enhance pinocytic capture of N-(2- hydroxypropyl)methacrylamide copolymers. - Biochim. Biophys. Acta, 799, 1-8, 1984.
-
(1984)
Biochim. Biophys. Acta
, vol.799
, pp. 1-8
-
-
Duncan, R.1
Cable, H.C.2
Rejmanova, P.3
Kopecek, J.4
Lloyd, J.B.5
-
40
-
-
0025283251
-
Immunogenicity of protein-N-(2-hydroxypropyl)-methacrylamide copolymer conjugates measured in A/J and B10 mice
-
FLANAGAN P.A., RIHOVA B., SUBR V., KOPECEK J. and DUNCAN R. - Immunogenicity of protein-N-(2-hydroxypropyl)-methacrylamide copolymer conjugates measured in A/J and B10 mice. - J. Bioact. Compat. Polymers, 5, 151-166, 1990.
-
(1990)
J. Bioact. Compat. Polymers
, vol.5
, pp. 151-166
-
-
Flanagan, P.A.1
Rihova, B.2
Subr, V.3
Kopecek, J.4
Duncan, R.5
-
41
-
-
0023450012
-
Effect of molecular weight (Mw) of N-(2-hydroxypropyl)-methacrylamide copolymers on body distribution and rate of excretion after subcutaneous intraperitoneal and intravenous administration to rats
-
SEYMOUR L.W., DUNCAN R., STROHALM J. and KOPECEK J. - Effect of molecular weight (Mw) of N-(2-hydroxypropyl)-methacrylamide copolymers on body distribution and rate of excretion after subcutaneous intraperitoneal and intravenous administration to rats. - J. Biomed. Mater. Res., 21, 1341-1358, 1987.
-
(1987)
J. Biomed. Mater. Res.
, vol.21
, pp. 1341-1358
-
-
Seymour, L.W.1
Duncan, R.2
Strohalm, J.3
Kopecek, J.4
-
42
-
-
0026063621
-
Soluble polymeric carriers for drug delivery. Part 4. Tissue autoradiography and following intravenous administration
-
GODDARD P., WILLIAMSON I., BROWN J., HUTCHINSON L.E., NICHOLLS J. and PETRAK K. - Soluble polymeric carriers for drug delivery. Part 4. Tissue autoradiography and following intravenous administration. -J. Bioact. Compat. Polymers, 6, 4-24, 1991.
-
(1991)
J. Bioact. Compat. Polymers
, vol.6
, pp. 4-24
-
-
Goddard, P.1
Williamson, I.2
Brown, J.3
Hutchinson, L.E.4
Nicholls, J.5
Petrak, K.6
-
43
-
-
0024801279
-
Anionic dyes, heparin, and heparinoids - The rediscovery of polyanionic antitumour agents
-
REGLESEN W. - Anionic dyes, heparin, and heparinoids - the rediscovery of polyanionic antitumour agents. - J. Natl. Cancer Inst., 81, 1920-1930, 1989.
-
(1989)
J. Natl. Cancer Inst.
, vol.81
, pp. 1920-1930
-
-
Reglesen, W.1
-
44
-
-
0025830568
-
Induction of cytokine production from human monocytes stimulated with alginate
-
OTTERLEI M., OSTGAARD K., SKJAK-BRAEK G., SMIDSROD O., SOON-SHIONG P. and ESPEVIK T. - Induction of cytokine production from human monocytes stimulated with alginate. - J. Immunother., 10, 286-291, 1991.
-
(1991)
J. Immunother.
, vol.10
, pp. 286-291
-
-
Otterlei, M.1
Ostgaard, K.2
Skjak-Braek, G.3
Smidsrod, O.4
Soon-Shiong, P.5
Espevik, T.6
-
45
-
-
0028997161
-
Alginates as a macromolecular drug delivery system for the antitumour agent daunomycin : Synthesis, controlled release properties and antitumour activity of alginate-cis-aconityl-daunomycin conjugates
-
AL-SHAMKHANI A. and DUNCAN R. - Alginates as a macromolecular drug delivery system for the antitumour agent daunomycin : synthesis, controlled release properties and antitumour activity of alginate-cis-aconityl-daunomycin conjugates. - Int. J. Pharm., 122, 107-119, 1995.
-
(1995)
Int. J. Pharm.
, vol.122
, pp. 107-119
-
-
Al-Shamkhani, A.1
Duncan, R.2
-
46
-
-
0025275020
-
Effect of the chemical modification of dextran on the degradation by dextranases
-
VERCAUTEREN R., BRUNEEL D., SCHACHT E. and DUNCAN R. - Effect of the chemical modification of dextran on the degradation by dextranases. - J. Bioactive Comp. Polymers, 5, 4-15, 1990.
-
(1990)
J. Bioactive Comp. Polymers
, vol.5
, pp. 4-15
-
-
Vercauteren, R.1
Bruneel, D.2
Schacht, E.3
Duncan, R.4
-
47
-
-
0042856133
-
Chemical modification of proteins and polysaccharides and its effect on enzyme-catalysed degradation
-
S.W. Shalaby Ed., Hanser Publishers, New York
-
SHALABY W.S.W. and PARK K. - Chemical modification of proteins and polysaccharides and its effect on enzyme-catalysed degradation. - In : Biomedical Polymers. Designed-to-degrade Systems, S.W. Shalaby Ed., Hanser Publishers, New York, 1994, pp. 213-258.
-
(1994)
Biomedical Polymers. Designed-to-degrade Systems
, pp. 213-258
-
-
Shalaby, W.S.W.1
Park, K.2
-
48
-
-
0028326685
-
New approaches to targeting bioactive compounds
-
KABANOV A.V. and ALAKHOV V.Y. - New approaches to targeting bioactive compounds. -J. Cont. Rel., 28, 15-35, 1994.
-
(1994)
J. Cont. Rel.
, vol.28
, pp. 15-35
-
-
Kabanov, A.V.1
Alakhov, V.Y.2
-
49
-
-
0028135121
-
Improved synthesis of adriamycin-conjugates poly(ethylene oxide)-poly(aspartic acid) block copolymer and formation of unimodal micellar structure with controlled amount of physically entrapped adriamycin
-
YOKAYAMA M., OKANO T., SAKURAI Y. and KATAOKA K. - Improved synthesis of adriamycin-conjugates poly(ethylene oxide)-poly(aspartic acid) block copolymer and formation of unimodal micellar structure with controlled amount of physically entrapped adriamycin. - J. Cont. Rel., 32, 269-277, 1994.
-
(1994)
J. Cont. Rel.
, vol.32
, pp. 269-277
-
-
Yokayama, M.1
Okano, T.2
Sakurai, Y.3
Kataoka, K.4
-
50
-
-
0027180686
-
Block copolymer micelles as vehicles for drug delivery
-
KATAOKA K., KWON G.S., YOKOYAMA M., OKANO T. and SAKURAI Y. - Block copolymer micelles as vehicles for drug delivery. -J. Cont. Rel., 24, 119-132, 1993.
-
(1993)
J. Cont. Rel.
, vol.24
, pp. 119-132
-
-
Kataoka, K.1
Kwon, G.S.2
Yokoyama, M.3
Okano, T.4
Sakurai, Y.5
-
51
-
-
7444257114
-
-
GB Patent Application 17024, 1991
-
ANGELUCCI F., BERSANI L., CARUSO M., RIPAMONTI M., RUGGIERI M. and SUARATO A. - GB Patent Application 17024, 1991.
-
-
-
Angelucci, F.1
Bersani, L.2
Caruso, M.3
Ripamonti, M.4
Ruggieri, M.5
Suarato, A.6
-
53
-
-
0029998325
-
Molecular characterization of polymeric antitumour drug carriers by size exclusion chromatography and universal calibration
-
in press
-
MENDICHI R., RIZZO V., GIGLI M. and GIACOMETTI SCHIERONI A. - Molecular characterization of polymeric antitumour drug carriers by size exclusion chromatography and universal calibration. - J. Liquid Chromatography, in press, 1996.
-
(1996)
J. Liquid Chromatography
-
-
Mendichi, R.1
Rizzo, V.2
Gigli, M.3
Giacometti Schieroni, A.4
-
54
-
-
0030272480
-
HPLC methods for the determination of bound and free doxorubicin and of bound and free galactosamine in methacrylamide polymer-drug conjugates
-
in press
-
CONFIGLIACCHI E., RAZZANO G., RIZZO V. and VIGEVANI A. - HPLC methods for the determination of bound and free doxorubicin and of bound and free galactosamine in methacrylamide polymer-drug conjugates. - J. Pharm. Biomed. Analysis, in press, 1996.
-
(1996)
J. Pharm. Biomed. Analysis
-
-
Configliacchi, E.1
Razzano, G.2
Rizzo, V.3
Vigevani, A.4
-
55
-
-
7444248714
-
PK1/PK2 lyophilised formulations, HPMA/doxorubicin conjugates with potentially improved antitumour activity
-
Budapest
-
CAVALLO A., ADAMI M., MAGRINI R. and COLOMBO G.-PK1/PK2 lyophilised formulations, HPMA/doxorubicin conjugates with potentially improved antitumour activity. - Proc. 1st World Meeting APGI/AVP, Budapest, 1995, pp. 843-844.
-
(1995)
Proc. 1st World Meeting APGI/AVP
, pp. 843-844
-
-
Cavallo, A.1
Adami, M.2
Magrini, R.3
Colombo, G.4
-
56
-
-
0025856232
-
Macromolecular prodrugs for use in targeted cancer chemotherapy : Melphalan covalently coupled to N-(2-hydroxypropyl)methacrylamide copolymers
-
DUNCAN R., HUME I.C., YARDLEY H.J., FLANAGAN P.A., ULBRICH K., SUBR V. and STROHALM J. - Macromolecular prodrugs for use in targeted cancer chemotherapy : melphalan covalently coupled to N-(2-hydroxypropyl)methacrylamide copolymers. -J. Cont. Rel., 16, 121-136, 1991.
-
(1991)
J. Cont. Rel.
, vol.16
, pp. 121-136
-
-
Duncan, R.1
Hume, I.C.2
Yardley, H.J.3
Flanagan, P.A.4
Ulbrich, K.5
Subr, V.6
Strohalm, J.7
-
57
-
-
0018897432
-
Antitumour activity of monomeric and polymeric cyclophosphamide derivative compound with in vitro hydrolysis
-
HIRANO T., RINGSDORF H.and ZAHARKO D. - Antitumour activity of monomeric and polymeric cyclophosphamide derivative compound with in vitro hydrolysis. - Cancer Res., 40, 2263-2267, 1980.
-
(1980)
Cancer Res.
, vol.40
, pp. 2263-2267
-
-
Hirano, T.1
Ringsdorf, H.2
Zaharko, D.3
-
58
-
-
0026498398
-
Anticancer agent coupled to polyaspartamide as drug carrier
-
GIAMMONA G., CARUSI B., CAVALLARO G., PITTARESI G. and PALAZZO S. -Anticancer agent coupled to polyaspartamide as drug carrier. - Eur. J. Pharm. Biopharm., 38, 159-162, 1992.
-
(1992)
Eur. J. Pharm. Biopharm.
, vol.38
, pp. 159-162
-
-
Giammona, G.1
Carusi, B.2
Cavallaro, G.3
Pittaresi, G.4
Palazzo, S.5
-
59
-
-
0343389727
-
Preparation of 4-nitrophenyl esters of poly[N-5-(2-hydroxyethyl) - L- glutamine] and coupling with bioactive agents
-
DEMARRE A. and SCHACHT E. - Preparation of 4-nitrophenyl esters of poly[N-5-(2-hydroxyethyl) - L- glutamine] and coupling with bioactive agents. - Makromol. Chem., Macromolecular Chemistry and Physics, 193, 3023-3030, 1992.
-
(1992)
Makromol. Chem., Macromolecular Chemistry and Physics
, vol.193
, pp. 3023-3030
-
-
Demarre, A.1
Schacht, E.2
-
60
-
-
0000268659
-
Pharmacologically active polymers. 17. Synthesis and characterization of polymeric derivatives of the antitumour agent methotrexate
-
PRZYBYLSKI M., FELL E., RINGSDORF H. and ZAHARKO D. - Pharmacologically active polymers. 17. Synthesis and characterization of polymeric derivatives of the antitumour agent methotrexate. - Makromol. Chem., 179, 1719-1733, 1978.
-
(1978)
Makromol. Chem.
, vol.179
, pp. 1719-1733
-
-
Przybylski, M.1
Fell, E.2
Ringsdorf, H.3
Zaharko, D.4
-
61
-
-
0019780744
-
Pharmacological and therapeutic properties of carrier bound methotrexate against tumour confined to a third space body compartment
-
CHU B.C.F. and HOWELL S.B. - Pharmacological and therapeutic properties of carrier bound methotrexate against tumour confined to a third space body compartment.-Pharmacol. Exp.Ther., 219, 389-393, 1981.
-
(1981)
Pharmacol. Exp.Ther.
, vol.219
, pp. 389-393
-
-
Chu, B.C.F.1
Howell, S.B.2
-
62
-
-
0025269381
-
Polymer drugs and polymeric drugs. Part VII. Antitumour conjugated polymeric drugs consisting of 5-fluorouracil and polyanionic polymers
-
YASHIMA E., UCHIDA S., AKASHI M., MIYAUCHI N., MORITA N. and MINOTA T. - Polymer drugs and polymeric drugs. Part VII. Antitumour conjugated polymeric drugs consisting of 5-fluorouracil and polyanionic polymers. - J. Bioact. and Compat. Polymers, 5, 53-64, 1990.
-
(1990)
J. Bioact. and Compat. Polymers
, vol.5
, pp. 53-64
-
-
Yashima, E.1
Uchida, S.2
Akashi, M.3
Miyauchi, N.4
Morita, N.5
Minota, T.6
-
63
-
-
0025984418
-
α-1,4-polygalactosamine immobilised 5-fluorouracils through hexamethylene spacer groups via urea bonds
-
OHYA Y., HUANG T. Z., OUCHIT., HASEGAWA K., TAMURA J., KADOWAKI K., MATSUMOTO T. and SUZUKI S. - α-1,4-polygalactosamine immobilised 5-fluorouracils through hexamethylene spacer groups via urea bonds. - J. Controlled Release, 17, 259-266, 1991.
-
(1991)
J. Controlled Release
, vol.17
, pp. 259-266
-
-
Ohya, Y.1
Huang, T.Z.2
Ouchi, T.3
Hasegawa, K.4
Tamura, J.5
Kadowaki, K.6
Matsumoto, T.7
Suzuki, S.8
-
64
-
-
0026593832
-
Synthesis and antitumour activity of 6-O-carboxymethyl chitin fixing 5-fluorouracil through pentamethylene, monomethylene spacer groups via amide, ester bonds
-
OHYA Y., INOSAKA K. and OUCHI T. - Synthesis and antitumour activity of 6-O-carboxymethyl chitin fixing 5-fluorouracil through pentamethylene, monomethylene spacer groups via amide, ester bonds - Chem. Pharm., Bull., 40, 559-561, 1992.
-
(1992)
Chem. Pharm., Bull.
, vol.40
, pp. 559-561
-
-
Ohya, Y.1
Inosaka, K.2
Ouchi, T.3
-
65
-
-
0029339453
-
Enantioselective release of 5-fluorouracil from N-(2-hydroxypropyl) methacrylamide-based copolymers via lysosomal enzymes
-
PUTNAM D.A. and KOPECEK J. - Enantioselective release of 5-fluorouracil from N-(2-hydroxypropyl) methacrylamide-based copolymers via lysosomal enzymes. - Bioconjugate Chem., 6, 483-492, 1995.
-
(1995)
Bioconjugate Chem.
, vol.6
, pp. 483-492
-
-
Putnam, D.A.1
Kopecek, J.2
-
67
-
-
0029089856
-
Molecular prodrugs of 5-fluorouracil.1. Synthesis and hydrolytic stability
-
NICHIFOR M., COESSENS V. and SCHACHT E. - Molecular prodrugs of 5-fluorouracil.1. Synthesis and hydrolytic stability. - J. Bioact. and Compat. Polymers, 10, 199-222, 1995.
-
(1995)
J. Bioact. and Compat. Polymers
, vol.10
, pp. 199-222
-
-
Nichifor, M.1
Coessens, V.2
Schacht, E.3
-
68
-
-
0029877192
-
Macromolecular prodrugs of 5-fluorouracil. 2. Enzymatic degradation
-
NICHIFOR M., SCHACHT E. and SEYMOUR L.W. - Macromolecular prodrugs of 5-fluorouracil. 2. Enzymatic degradation. - J. Cont. Rel., 39, 79-92, 1996.
-
(1996)
J. Cont. Rel.
, vol.39
, pp. 79-92
-
-
Nichifor, M.1
Schacht, E.2
Seymour, L.W.3
-
69
-
-
0027267901
-
Epirubicin and doxorubicin. A comparison of their characteristics, therapeutic activity and toxicity
-
LAUNCHBURY A.P. and HABBOUBI N. - Epirubicin and doxorubicin. A comparison of their characteristics, therapeutic activity and toxicity. - Cancer Treatment Reviews, 19, 197-228, 1993.
-
(1993)
Cancer Treatment Reviews
, vol.19
, pp. 197-228
-
-
Launchbury, A.P.1
Habboubi, N.2
-
70
-
-
0029989659
-
Anthracyclines : Review of genotoxicity and carcinogenicity studies
-
MAZUE G., WILLIAMS G.M., IATROPOULOS M.J., NEWMAN A.J., SAMMARTINI U., PULCI R., CASTELLINO S., SCAMPINI G., BRUGHERA M., IMONDI A.R. and PODESTÁ A. - Anthracyclines : review of genotoxicity and carcinogenicity studies. - Int. J. Oncol., 8, 525-536, 1996.
-
(1996)
Int. J. Oncol.
, vol.8
, pp. 525-536
-
-
Mazue, G.1
Williams, G.M.2
Iatropoulos, M.J.3
Newman, A.J.4
Sammartini, U.5
Pulci, R.6
Castellino, S.7
Scampini, G.8
Brughera, M.9
Imondi, A.R.10
Podestá, A.11
-
71
-
-
0029156803
-
Anthracyclines : A review of general and special toxicity studies
-
MAZUE G., IATROPOULOS M.J., IMONDI A.R., CASTELLINO S., BRUGHERA M., PODESTÁ A., DELLA TORRE P. and MONETA D. - Anthracyclines : a review of general and special toxicity studies. - Int. J. Oncol., 7, 713-726, 1995.
-
(1995)
Int. J. Oncol.
, vol.7
, pp. 713-726
-
-
Mazue, G.1
Iatropoulos, M.J.2
Imondi, A.R.3
Castellino, S.4
Brughera, M.5
Podestá, A.6
Della Torre, P.7
Moneta, D.8
-
72
-
-
0028954776
-
Site-directed delivery of anthracyclines for the treatment of cancer
-
TRAIL P., WILLNER D. and HELLESTROM K.E.- Site-directed delivery of anthracyclines for the treatment of cancer. - Drug Dev. Res., 34, 196-209, 1995.
-
(1995)
Drug Dev. Res.
, vol.34
, pp. 196-209
-
-
Trail, P.1
Willner, D.2
Hellestrom, K.E.3
-
73
-
-
49549170184
-
Poly[N-(hydroxypropyl)-methacrylamide] - I. Radical polymerisation and copolymerisation
-
KOPECEK J. and BAZILOVA H. - Poly[N-(hydroxypropyl)-methacrylamide] - I. Radical polymerisation and copolymerisation. - Eur. Polymer J., 9, 7-14, 1973.
-
(1973)
Eur. Polymer J.
, vol.9
, pp. 7-14
-
-
Kopecek, J.1
Bazilova, H.2
-
74
-
-
0002017918
-
Clinical and pharmacokinetic phase I study of PK1 (HPMA)copolymer doxorubicin
-
VASEY P., DUNCAN R., TWELVES C., KAYE S. B., STROLIN-BENEDETTI M., and CASSIDY J. -Clinical and pharmacokinetic phase I study of PK1 (HPMA)copolymer doxorubicin. - Annals of Oncology, 7, 97, 1996.
-
(1996)
Annals of Oncology
, vol.7
, pp. 97
-
-
Vasey, P.1
Duncan, R.2
Twelves, C.3
Kaye, S.B.4
Strolin-Benedetti, M.5
Cassidy, J.6
-
75
-
-
0026561607
-
Preclinical evaluation of polymer-bound doxorubicin
-
DUNCAN R., SEYMOUR L.W., O'HARE K.B., FLANAGAN P.A., WEDGE S.R., HUME I.C., ULBRICH K., STROHALM J., SUBR V., SPREAFICO F., GRANDI M., RIPAMONTI M., FARAO M. and SUARATO A. - Preclinical evaluation of polymer-bound doxorubicin. - J. Cont. Rel., 19, 331-346, 1992.
-
(1992)
J. Cont. Rel.
, vol.19
, pp. 331-346
-
-
Duncan, R.1
Seymour, L.W.2
O'Hare, K.B.3
Flanagan, P.A.4
Wedge, S.R.5
Hume, I.C.6
Ulbrich, K.7
Strohalm, J.8
Subr, V.9
Spreafico, F.10
Grandi, M.11
Ripamonti, M.12
Farao, M.13
Suarato, A.14
-
76
-
-
0027130079
-
Polymeric drug-carriers containing doxorubicin and melanocyte-stimulating hormone : In vitro and in vivo evaluation against murine melanoma
-
O'HARE K.B., DUNCAN R., STROHALM J., ULBRICH K. and KOPECKOVA P. - Polymeric drug-carriers containing doxorubicin and melanocyte-stimulating hormone : in vitro and in vivo evaluation against murine melanoma. - J. Drug Targeting, 1, 217-229, 1993.
-
(1993)
J. Drug Targeting
, vol.1
, pp. 217-229
-
-
O'Hare, K.B.1
Duncan, R.2
Strohalm, J.3
Ulbrich, K.4
Kopeckova, P.5
-
77
-
-
0024469053
-
Anticancer agents coupled to N-(2-hydroxypropyl) methacrylamide copolymers. 3. Evaluation of adriamycin conjugates against mouse leukæmia L1210 in vivo
-
DUNCAN R., HUME I.C., KOPECKOVA P., ULBRICH K., STROHALM J. and KOPECEK J. - Anticancer agents coupled to N-(2-hydroxypropyl) methacrylamide copolymers. 3. Evaluation of adriamycin conjugates against mouse leukæmia L1210 in vivo. - J. Cont. Rel., 10, 51-63, 1989.
-
(1989)
J. Cont. Rel.
, vol.10
, pp. 51-63
-
-
Duncan, R.1
Hume, I.C.2
Kopeckova, P.3
Ulbrich, K.4
Strohalm, J.5
Kopecek, J.6
-
78
-
-
7444253090
-
Reduction of anticancer drug toxicity
-
Pharmacologic, Biologic, Immunologic and Gene Therapeutic Approaches, W.J. Zeller, G. Eisenbrand and K. Hellmann Eds.
-
DUNCAN R. - Reduction of anticancer drug toxicity. - In : Pharmacologic, Biologic, Immunologic and Gene Therapeutic Approaches, W.J. Zeller, G. Eisenbrand and K. Hellmann Eds., Contrib. Oncol., 48, 170-180, 1995.
-
(1995)
Contrib. Oncol.
, vol.48
, pp. 170-180
-
-
Duncan, R.1
-
79
-
-
0025918134
-
Reduced cardiotoxicity of doxorubicin administered in the form of N-(2-hydroxypropyl)methacrylamide conjugates : An experimental study in the rat
-
YEUNG T.K., HOPEWELL J.W., REZZANI G., SIMMONDS R.H., SEYMOUR L.W., DUNCAN R., BELLINI O., GRANDI M., SPREAFICO F., STROHALM J. and ULBRICH K. - Reduced cardiotoxicity of doxorubicin administered in the form of N-(2-hydroxypropyl)methacrylamide conjugates : an experimental study in the rat. - Cancer Chemother. Pharmacol., 29, 105-111, 1991.
-
(1991)
Cancer Chemother. Pharmacol.
, vol.29
, pp. 105-111
-
-
Yeung, T.K.1
Hopewell, J.W.2
Rezzani, G.3
Simmonds, R.H.4
Seymour, L.W.5
Duncan, R.6
Bellini, O.7
Grandi, M.8
Spreafico, F.9
Strohalm, J.10
Ulbrich, K.11
-
80
-
-
0024398880
-
Biocompatibility of N-(2-hydroxypropyl)methacrylamide copolymers containing adriamycin. Immunogenicity, effect of hæmatopoietic stem cells in bone marrow in vivo and effect on mouse splenocytes and human peripheral blood lymphocytes in vitro
-
RIHOVA B., ULBRICH K., STROHALM J., VETVICKA V., BILEJ M., DUNCAN R. and KOPECEK J. - Biocompatibility of N-(2-hydroxypropyl)methacrylamide copolymers containing adriamycin. Immunogenicity, effect of hæmatopoietic stem cells in bone marrow in vivo and effect on mouse splenocytes and human peripheral blood lymphocytes in vitro. - Biomaterials, 10, 335-342, 1989.
-
(1989)
Biomaterials
, vol.10
, pp. 335-342
-
-
Rihova, B.1
Ulbrich, K.2
Strohalm, J.3
Vetvicka, V.4
Bilej, M.5
Duncan, R.6
Kopecek, J.7
-
82
-
-
0020682412
-
Targeting of N-(2-hydroxypropyl)methacrylamide copolymers to liver by incorporation of galactose residues
-
DUNCAN R., KOPECEK J., REJMANOVA P. and LLOYD J.B. -Targeting of N-(2-hydroxypropyl)methacrylamide copolymers to liver by incorporation of galactose residues. - Biochim. Biophys. Acta, 755, 518-521, 1983.
-
(1983)
Biochim. Biophys. Acta
, vol.755
, pp. 518-521
-
-
Duncan, R.1
Kopecek, J.2
Rejmanova, P.3
Lloyd, J.B.4
-
83
-
-
0025809808
-
Pharmacokinetics of a polymeric drug carrier targeted to the hepatocyte galactose receptor
-
SEYMOUR L.W., ULBRICH K., STROHALM J. and DUNCAN R.- Pharmacokinetics of a polymeric drug carrier targeted to the hepatocyte galactose receptor. - Brit. J. Cancer, 63, 859-866, 1991.
-
(1991)
Brit. J. Cancer
, vol.63
, pp. 859-866
-
-
Seymour, L.W.1
Ulbrich, K.2
Strohalm, J.3
Duncan, R.4
-
84
-
-
0026512810
-
Evaluation of protein-N-(2-hydroxypropyl)methacrylamide copolymer conjugates as targetable drug-carriers. 2. Body distribution of conjugates containing transferrin, anti-transferrin receptor antibody or anti-Thy 1.2 antibody and effectiveness of transferrin-containing daunomycin conjugates against mouse L1210 leukæmia in vivo
-
FLANAGAN P., DUNCAN R., SUBR V., ULBRICH K., KOPECKOVA P. and KOPECEK J. - Evaluation of protein-N-(2-hydroxypropyl)methacrylamide copolymer conjugates as targetable drug-carriers. 2. Body distribution of conjugates containing transferrin, anti-transferrin receptor antibody or anti-Thy 1.2 antibody and effectiveness of transferrin-containing daunomycin conjugates against mouse L1210 leukæmia in vivo. - J. Cont. Rel., 18, 25-38, 1992.
-
(1992)
J. Cont. Rel.
, vol.18
, pp. 25-38
-
-
Flanagan, P.1
Duncan, R.2
Subr, V.3
Ulbrich, K.4
Kopeckova, P.5
Kopecek, J.6
-
85
-
-
0026561594
-
Antibody targeted cyclosporin A
-
RIHOVA B., JEGOROV A., STROHALM J., MATHA V., ROSSMANN P., FORNUSEK L. and ULBRlCH K. - Antibody targeted cyclosporin A. - J. Cont. Rel., 19, 25-40, 1992.
-
(1992)
J. Cont. Rel.
, vol.19
, pp. 25-40
-
-
Rihova, B.1
Jegorov, A.2
Strohalm, J.3
Matha, V.4
Rossmann, P.5
Fornusek, L.6
Ulbrlch, K.7
-
86
-
-
0029662276
-
123I-labelled N-(2-hydroxypropyl) methacrylamide copolymer-doxorubicin conjugate containing galactosamine following intravenous administration to nude mice bearing hepatic human colon carcinoma
-
123I-labelled N-(2-hydroxypropyl) methacrylamide copolymer-doxorubicin conjugate containing galactosamine following intravenous administration to nude mice bearing hepatic human colon carcinoma. - J. Drug Targeting, 3, 385-390, 1996.
-
(1996)
J. Drug Targeting
, vol.3
, pp. 385-390
-
-
Pimm, M.V.1
Perkins, A.C.2
Strohalm, J.3
Ulbrich, K.4
Duncan, R.5
-
87
-
-
0027274717
-
Phase I clinical and pharmacokinetic trial of dextran conjugated doxorubicin (AD-70, DOX-OXD)
-
DANHAUSER-RIEDL S., HAUSMANN E., SCHICK H.D., BENDER R., DIETZFELBINGER H., RASTETTER J. and HANAUSKE A.R. - Phase I clinical and pharmacokinetic trial of dextran conjugated doxorubicin (AD-70, DOX-OXD). - Investigational New Drugs, 11 (2-3), 187-195, 1993.
-
(1993)
Investigational New Drugs
, vol.11
, Issue.2-3
, pp. 187-195
-
-
Danhauser-Riedl, S.1
Hausmann, E.2
Schick, H.D.3
Bender, R.4
Dietzfelbinger, H.5
Rastetter, J.6
Hanauske, A.R.7
-
88
-
-
0023829660
-
Anticancer agents coupled to N-(2-hydroxypropyl)methacrylamide copolymers. 2. Evaluation of daunomycin conjugates in vivo against L1210 leukæmia
-
DUNCAN R., KOPECKOVA-REJMANOVA P., STROHALM J., HUME I., LLOYD J.B. and KOPECEK J. - Anticancer agents coupled to N-(2-hydroxypropyl)methacrylamide copolymers. 2. Evaluation of daunomycin conjugates in vivo against L1210 leukæmia. - Brit. J. Cancer, 57, 147-156, 1988.
-
(1988)
Brit. J. Cancer
, vol.57
, pp. 147-156
-
-
Duncan, R.1
Kopeckova-Rejmanova, P.2
Strohalm, J.3
Hume, I.4
Lloyd, J.B.5
Kopecek, J.6
-
89
-
-
7444257115
-
Synthesis and biological evaluation of polymer-bound 3′-deamino-3′[2(S)-methoxy-4-morpholinyl] doxorubicin
-
Paris, 19-23 Sept.
-
ANGELUCCI F., BALLINARI D.and FARAO M. - Synthesis and biological evaluation of polymer-bound 3′-deamino-3′[2(S)-methoxy-4-morpholinyl] doxorubicin. - Proc. XIII Int. Symp. Med. Chem., Paris, 19-23 Sept., 1994.
-
(1994)
Proc. XIII Int. Symp. Med. Chem.
-
-
Angelucci, F.1
Ballinari, D.2
Farao, M.3
-
90
-
-
0028046007
-
Tissue distribution of macromolecular conjugate adriamycin linked to oxidized dextran, in rat and mouse bearing tumour-cells
-
MUNECHIKA K., SOGAME Y., KISHI N., KAWABATA Y., UEDA Y., YAMANOUCHI K. and YOKOYAMA K. - Tissue distribution of macromolecular conjugate adriamycin linked to oxidized dextran, in rat and mouse bearing tumour-cells. - Biol. Pharm. Bull., 17 (9), 1193-1198, 1994.
-
(1994)
Biol. Pharm. Bull.
, vol.17
, Issue.9
, pp. 1193-1198
-
-
Munechika, K.1
Sogame, Y.2
Kishi, N.3
Kawabata, Y.4
Ueda, Y.5
Yamanouchi, K.6
Yokoyama, K.7
-
91
-
-
0017874190
-
Higher antitumour efficacy of daunomycin when linked to dextran : In vivo and in vitro studies
-
BERNSTEIN A., HURWITZ E. and ARNON R. - Higher antitumour efficacy of daunomycin when linked to dextran : in vivo and in vitro studies. - J. Natl. Cancer Inst., 60, 379-384, 1978.
-
(1978)
J. Natl. Cancer Inst.
, vol.60
, pp. 379-384
-
-
Bernstein, A.1
Hurwitz, E.2
Arnon, R.3
-
92
-
-
0025987026
-
Anthracycline immunoconjugates prepared by a site-specific linkage via an amino-dextran intermediate carrier
-
SHIH LB., GOLDENBERG D.M., XUAN H., LU H., SHARKEY R.M. and HALL T.C. - Anthracycline immunoconjugates prepared by a site-specific linkage via an amino-dextran intermediate carrier. - Cancer Res., 51, 4192-4198, 1991.
-
(1991)
Cancer Res.
, vol.51
, pp. 4192-4198
-
-
Shih, L.B.1
Goldenberg, D.M.2
Xuan, H.3
Lu, H.4
Sharkey, R.M.5
Hall, T.C.6
-
93
-
-
0029122610
-
In vivo and in vitro antitumour activity of CM-chitin immobilized doxorubicins by lysosomal digestible tetrapeptide spacer groups
-
OHYA Y., NONOMURA K. and OUCHI T. - In vivo and in vitro antitumour activity of CM-chitin immobilized doxorubicins by lysosomal digestible tetrapeptide spacer groups. - J. Bioact. Compat. Polymers, 10, 223-234, 1995.
-
(1995)
J. Bioact. Compat. Polymers
, vol.10
, pp. 223-234
-
-
Ohya, Y.1
Nonomura, K.2
Ouchi, T.3
-
94
-
-
0028827303
-
Synthesis of carboxymethylpullulan-peptide-doxorubicin conjugates and their properties
-
NOGUSA H., YANO T., OKUNO S., HAMANA H. and INOUE K. - Synthesis of carboxymethylpullulan-peptide-doxorubicin conjugates and their properties. - Chem. Pharm. Bull., 43, 1931-1936, 1995.
-
(1995)
Chem. Pharm. Bull.
, vol.43
, pp. 1931-1936
-
-
Nogusa, H.1
Yano, T.2
Okuno, S.3
Hamana, H.4
Inoue, K.5
-
95
-
-
0029872673
-
5-(2-hydroxyethyl)-L-glutamine]
-
5-(2-hydroxyethyl)-L-glutamine]. - J. Cont. Rel., 38, 245-266, 1996.
-
(1996)
J. Cont. Rel.
, vol.38
, pp. 245-266
-
-
Hoes, C.J.T.1
Ankone, M.2
Grootoonk, J.3
Feijen, J.4
Van Der Struik, E.5
Van Doornmalen, A.6
Pham, D.7
De Man, A.8
Van Ettekoven, A.9
Schlachter, I.10
Boon, P.J.11
Kaspersen, F.12
Bos, E.S.13
-
96
-
-
0025853550
-
Changes in the toxicity and therapeutic efficacy of daunorubicin linked with a biodegradable carrier
-
HRDINA R., BOGUSOVA A., KUNOVA A. and KVETINA J. - Changes in the toxicity and therapeutic efficacy of daunorubicin linked with a biodegradable carrier. - Neoplasma, 38 (3), 265-273, 1991.
-
(1991)
Neoplasma
, vol.38
, Issue.3
, pp. 265-273
-
-
Hrdina, R.1
Bogusova, A.2
Kunova, A.3
Kvetina, J.4
-
97
-
-
0027390175
-
Biological properties of adriamycin bound to biodegradable polymeric carriers
-
HOES C.J.T., GROOTOONK J., DUNCAN R., HUME I.C., BHAKOO M., BOUMA, J.M.W. and FEIJEN J. - Biological properties of adriamycin bound to biodegradable polymeric carriers. - J. Cont. Rel., 23, 37-53, 1993.
-
(1993)
J. Cont. Rel.
, vol.23
, pp. 37-53
-
-
Hoes, C.J.T.1
Grootoonk, J.2
Duncan, R.3
Hume, I.C.4
Bhakoo, M.5
Bouma, J.M.W.6
Feijen, J.7
-
98
-
-
0025065116
-
Increased effect of doxorubicin linked to pyran copolymer in the intracavity treatment of human ovarian carcinoma in nude mice
-
PRATESI G., TORTORETO M. and ZUNINO F. - Increased effect of doxorubicin linked to pyran copolymer in the intracavity treatment of human ovarian carcinoma in nude mice. - Reg. Cancer Treat., 3, 40-43, 1990.
-
(1990)
Reg. Cancer Treat.
, vol.3
, pp. 40-43
-
-
Pratesi, G.1
Tortoreto, M.2
Zunino, F.3
-
99
-
-
7444227194
-
Enhancement of antitumour activity of daunomycin by conjugation to a new toxicity modulator, amphoteric branched polypeptide
-
Amsterdam, 12-15 March
-
GAAL D. and HUDECZ F. - Enhancement of antitumour activity of daunomycin by conjugation to a new toxicity modulator, amphoteric branched polypeptide. - Proc. 9th NCI-EORTC Symp. on New Drugs in Cancer Therapy, Amsterdam, 12-15 March, (410), 116, 1996.
-
(1996)
Proc. 9th NCI-EORTC Symp. on New Drugs in Cancer Therapy
, Issue.410
, pp. 116
-
-
Gaal, D.1
Hudecz, F.2
-
100
-
-
0022344726
-
Poly-L-aspartic acid as a carrier for doxorubicin : A comparative in vivo study of free and polymer-bound drug
-
PRATESI G., SAVI G., PEZZONI G., BELLINI O., PENCO S., TINELLI S. and ZUNINO F. - Poly-L-aspartic acid as a carrier for doxorubicin : a comparative in vivo study of free and polymer-bound drug. - Br. J. Cancer, 52, 841-848, 1985.
-
(1985)
Br. J. Cancer
, vol.52
, pp. 841-848
-
-
Pratesi, G.1
Savi, G.2
Pezzoni, G.3
Bellini, O.4
Penco, S.5
Tinelli, S.6
Zunino, F.7
-
101
-
-
0028158713
-
Evaluation of poly(glutamic acid, alanine, tyrosine) (1:1:1) as a lung-specific drug delivery system I. Biocompatibility and studies on biodistribution in the rat
-
SGOURAS D.N.F. and DUNCAN R. - Evaluation of poly(glutamic acid, alanine, tyrosine) (1:1:1) as a lung-specific drug delivery system I. Biocompatibility and studies on biodistribution in the rat. - STP Pharma Sci., 4, 87-94, 1994.
-
(1994)
STP Pharma Sci.
, vol.4
, pp. 87-94
-
-
Sgouras, D.N.F.1
Duncan, R.2
-
102
-
-
0028467797
-
Strategies for covalent attachment of doxorubicin to poly(PEG-Lys), a new water soluble poly(ether urethane)
-
NATHAN A., ZALIPSKY S. and KOHN J. - Strategies for covalent attachment of doxorubicin to poly(PEG-Lys), a new water soluble poly(ether urethane). - J. Bioact. Compat. Pol., 9 (3), 239-251, 1994.
-
(1994)
J. Bioact. Compat. Pol.
, vol.9
, Issue.3
, pp. 239-251
-
-
Nathan, A.1
Zalipsky, S.2
Kohn, J.3
-
103
-
-
0028969911
-
Poly(ethyleneglycol) end-capped with doxorubicin via ester, amide or schiff-base bond
-
OHYA Y., KURODA H., HIRAI K. and OUCHI T. - Poly(ethyleneglycol) end-capped with doxorubicin via ester, amide or schiff-base bond. -J. Bioact. Compat. Polymers, 10 (1), 51-66, 1995.
-
(1995)
J. Bioact. Compat. Polymers
, vol.10
, Issue.1
, pp. 51-66
-
-
Ohya, Y.1
Kuroda, H.2
Hirai, K.3
Ouchi, T.4
-
104
-
-
0029340354
-
Polyethylene glycol-doxorubicin conjugates containing beta-lactamase-sensitive linkers
-
SENTER P.D., SVENSSON H.P., SCHREIBER G.J., RODRIGUEZ J.L. and VRUDHULA V.M. - Polyethylene glycol)-doxorubicin conjugates containing beta-lactamase-sensitive linkers. - Bioconj. Chem., 6 (4), 1043-1802, 1995.
-
(1995)
Bioconj. Chem.
, vol.6
, Issue.4
, pp. 1043-1802
-
-
Senter, P.D.1
Svensson, H.P.2
Schreiber, G.J.3
Rodriguez, J.L.4
Vrudhula, V.M.5
-
105
-
-
0029129341
-
Synthesis and evaluation of macromolecular prodrugs of mitomycin C
-
DE MARRE A., SOYEZ H., SCACHT E., SHOAIBI M.A., SEYMOUR L.W. and RIHOVA B. - Synthesis and evaluation of macromolecular prodrugs of mitomycin C. - J. Cont. Rel., 36, 87-97, 1995.
-
(1995)
J. Cont. Rel.
, vol.36
, pp. 87-97
-
-
De Marre, A.1
Soyez, H.2
Scacht, E.3
Shoaibi, M.A.4
Seymour, L.W.5
Rihova, B.6
-
106
-
-
0023268773
-
Development of a novel polymeric prodrug of mitomycin C, mitomycin C-dextran conjugate with anionic charge. II. Disposition and pharmacokinetics following intravenous and intramuscular administration
-
TAKAKURA Y., ATSUMI R., HASHIDA M. and SEZAKI H. - Development of a novel polymeric prodrug of mitomycin C, mitomycin C-dextran conjugate with anionic charge. II. Disposition and pharmacokinetics following intravenous and intramuscular administration. - Int. J. Pharm., 37, 145-154, 1987.
-
(1987)
Int. J. Pharm.
, vol.37
, pp. 145-154
-
-
Takakura, Y.1
Atsumi, R.2
Hashida, M.3
Sezaki, H.4
-
107
-
-
0023240259
-
Development of a novel polymeric prodrug of mitomycin C, mitomycin C-dextran conjugate with anionic charge. I. Physicochemical characteristics and in vivo and in vitro antitumour activities
-
TAKAKURAY., KITAJIMA M., MATSUMOTO S., HASHIDA M. and SEZAKI H. - Development of a novel polymeric prodrug of mitomycin C, mitomycin C-dextran conjugate with anionic charge. I. Physicochemical characteristics and in vivo and in vitro antitumour activities. - Int. J. Pharm., 37, 135-143, 1987.
-
(1987)
Int. J. Pharm.
, vol.37
, pp. 135-143
-
-
Takakura, Y.1
Kitajima, M.2
Matsumoto, S.3
Hashida, M.4
Sezaki, H.5
-
108
-
-
7444234539
-
Synthesis and evaluation of poly(amido amine)-mitomycin C conjugates
-
January 10-12, London
-
FLANAGAN P.A., RANUCCI E., BIGNOTTI F., FERRUTI P. and DUNCAN R. - Synthesis and evaluation of poly(amido amine)-mitomycin C conjugates. - Proc. 1st Int. Symp. Polymer Therapeutics, January 10-12, London, 52, 1996.
-
(1996)
Proc. 1st Int. Symp. Polymer Therapeutics
, pp. 52
-
-
Flanagan, P.A.1
Ranucci, E.2
Bignotti, F.3
Ferruti, P.4
Duncan, R.5
-
109
-
-
0021739518
-
Physicochemical and antitumour characteristics of some polyamino acid prodrugs of mitomycin C
-
ROOS C.F., MATSUMOTO S., TAKAKURA Y., HASHIDA M. and SEZAKIH. - Physicochemical and antitumour characteristics of some polyamino acid prodrugs of mitomycin C. - Int. J. Pharm., 22, 75-87, 1984.
-
(1984)
Int. J. Pharm.
, vol.22
, pp. 75-87
-
-
Roos, C.F.1
Matsumoto, S.2
Takakura, Y.3
Hashida, M.4
Sezaki, H.5
-
110
-
-
7444251324
-
-
Polymer-bound paclitaxel derivatives. - US Patent, 5,362,831, 1994
-
MONGELLI N., PESENTI E., SUARATO A. and BIASOLI G. - Polymer-bound paclitaxel derivatives. - US Patent, 5,362,831, 1994.
-
-
-
Mongelli, N.1
Pesenti, E.2
Suarato, A.3
Biasoli, G.4
-
111
-
-
3542993954
-
Synthesis and biological activity of water soluble polymer-bound Taxol derivatives
-
PESENTI E., FRANZETTI C., BIASOLI G., CIOMEI M., PASTON W., MARSIGLIO A., STEGNJAICH S., MONGELLI N. and GRANDI M. - Synthesis and biological activity of water soluble polymer-bound Taxol derivatives. - Proc. Am. Assoc. Cancer Res., 1824, 1995.
-
(1995)
Proc. Am. Assoc. Cancer Res.
, pp. 1824
-
-
Pesenti, E.1
Franzetti, C.2
Biasoli, G.3
Ciomei, M.4
Paston, W.5
Marsiglio, A.6
Stegnjaich, S.7
Mongelli, N.8
Grandi, M.9
-
112
-
-
0030071043
-
Drug delivery systems : Water soluble Taxol 2′-poly(ethylene glycol) ester prodrugs, Design and in vivo effectiveness
-
GREENWALD R.B., GILBERT C.W., PENDRI A., CONOVER C.D., XIA J. and MARTINEZ A. - Drug delivery systems : water soluble Taxol 2′-poly(ethylene glycol) ester prodrugs, Design and in vivo effectiveness. - J. Med. Chem., 39 (2), 424-431, 1996.
-
(1996)
J. Med. Chem.
, vol.39
, Issue.2
, pp. 424-431
-
-
Greenwald, R.B.1
Gilbert, C.W.2
Pendri, A.3
Conover, C.D.4
Xia, J.5
Martinez, A.6
-
114
-
-
0026553237
-
In vivo antitumour activity of FCE-23762, a methoxymorpholino derivative of doxorubicin active on doxorubicin resistant tumour cells
-
RIPAMONTI M., PEZZONI G., PESENTI E., PASTORI A., FARAO M., BARGIOTTI A., SUARATO A., SPREAFICO F. and GRANDI M. - In vivo antitumour activity of FCE-23762, a methoxymorpholino derivative of doxorubicin active on doxorubicin resistant tumour cells. - Brit. J. Cancer, 65, 703-707, 1992.
-
(1992)
Brit. J. Cancer
, vol.65
, pp. 703-707
-
-
Ripamonti, M.1
Pezzoni, G.2
Pesenti, E.3
Pastori, A.4
Farao, M.5
Bargiotti, A.6
Suarato, A.7
Spreafico, F.8
Grandi, M.9
-
115
-
-
0025343062
-
Characterization and anticancer activity of the micelle-forming polymeric anticancer drug adriamycin-conjugated poly(ethyleneglycol)-poly(aspartic acid) block copolymer
-
YOKOYAMA M., MIYAUCHI M., YAMADA N., OKANO T., SAKURAI Y., KATAOKA K. and INOUE S. - Characterization and anticancer activity of the micelle-forming polymeric anticancer drug adriamycin-conjugated poly(ethyleneglycol)-poly(aspartic acid) block copolymer. - Cancer Res., 50, 1693-1700, 1990.
-
(1990)
Cancer Res.
, vol.50
, pp. 1693-1700
-
-
Yokoyama, M.1
Miyauchi, M.2
Yamada, N.3
Okano, T.4
Sakurai, Y.5
Kataoka, K.6
Inoue, S.7
-
116
-
-
0025874282
-
Toxicity and antitumour activity against solid tumours of micelle-forming polymeric anticancer drug and its extremely long circulation in blood
-
YOKOYAMA M., OKANO T., SAKURAI Y., EKIMOTO H., SHIBAZAKI C. and KATAOKA K. - Toxicity and antitumour activity against solid tumours of micelle-forming polymeric anticancer drug and its extremely long circulation in blood. - Cancer Res., 51, 3229-3236, 1991.
-
(1991)
Cancer Res.
, vol.51
, pp. 3229-3236
-
-
Yokoyama, M.1
Okano, T.2
Sakurai, Y.3
Ekimoto, H.4
Shibazaki, C.5
Kataoka, K.6
-
117
-
-
0030550532
-
Polymeric prodrugs of mitomycin C
-
SOYEZ H., SCHACHT E., DEMARRE A. and SEYMOUR L.W. - Polymeric prodrugs of mitomycin C. - Macromol. Symp., 103, 163-176, 1996.
-
(1996)
Macromol. Symp.
, vol.103
, pp. 163-176
-
-
Soyez, H.1
Schacht, E.2
Demarre, A.3
Seymour, L.W.4
-
118
-
-
0028153459
-
A polymer-triton X-100 conjugate capable of pH-dependent red blood cell lysis : A model system illustrating the possibility of drug delivery within acidic intracellular compartments
-
DUNCAN R., SGOURAS D., TUBUKU-METZGER A., RANUCCI E., BIGNOTTI F. and FERRUTI P. - A polymer-triton X-100 conjugate capable of pH-dependent red blood cell lysis : a model system illustrating the possibility of drug delivery within acidic intracellular compartments. - J. Drug Targeting, 2, 341-347, 1994.
-
(1994)
J. Drug Targeting
, vol.2
, pp. 341-347
-
-
Duncan, R.1
Sgouras, D.2
Tubuku-Metzger, A.3
Ranucci, E.4
Bignotti, F.5
Ferruti, P.6
-
119
-
-
0027517088
-
The taxoids : Paclitaxel (Taxol) and docetaxel (Taxotere)
-
PAZDUR R., KUDELKA A.P., KAVANAGH J.J., COHEN P.R. and RABER M.R. -The taxoids : paclitaxel (Taxol) and docetaxel (Taxotere). - Cancer Treatment Rev., 19, 351-386, 1993.
-
(1993)
Cancer Treatment Rev.
, vol.19
, pp. 351-386
-
-
Pazdur, R.1
Kudelka, A.P.2
Kavanagh, J.J.3
Cohen, P.R.4
Raber, M.R.5
-
120
-
-
0028882838
-
Preclinical pharmacology of docetaxel
-
BISSERY M.C. - Preclinical pharmacology of docetaxel. - Eur. J. Cancer, 31(A), Suppl. 4, S1-S6, 1995.
-
(1995)
Eur. J. Cancer
, vol.31 A
, Issue.4 SUPPL.
-
-
Bissery, M.C.1
-
121
-
-
0027373835
-
Review of platinum anticancer compounds
-
GORDON M. and HOLLANDER S. - Review of platinum anticancer compounds. - J. Medicine, 24, 209-265, 1993.
-
(1993)
J. Medicine
, vol.24
, pp. 209-265
-
-
Gordon, M.1
Hollander, S.2
-
124
-
-
0022803231
-
Cisplatinum(II) complexes of carboxymethyl dextran as potential antitumour agents. I. Preparation and characterization
-
SCHECHTER B., PAUZNER R., ARNON R. and WILCHEK - Cisplatinum(II) complexes of carboxymethyl dextran as potential antitumour agents. I. Preparation and characterization. - Cancer Biochem. Biophys., 8, 277-287, 1986.
-
(1986)
Cancer Biochem. Biophys.
, vol.8
, pp. 277-287
-
-
Schechter, B.1
Pauzner, R.2
Arnon, R.3
Wilchek4
-
125
-
-
0024443207
-
Soluble polymers as carriers of cisplatinum
-
SCHECHTER B., NEUMANN A., WILCHEK M. and ARNON R. - Soluble polymers as carriers of cisplatinum. - J. Cont. Rel., 10, 75-87, 1989.
-
(1989)
J. Cont. Rel.
, vol.10
, pp. 75-87
-
-
Schechter, B.1
Neumann, A.2
Wilchek, M.3
Arnon, R.4
-
126
-
-
0025873386
-
Biodistribution of trans-1,2-diaminocyclohexane-trimetallito-platinum(II) attached to macromolecular carriers. I. Poly(hydroxyethyl-D,L-asparagine) carrier
-
FILIPOVÁ-VOPRÁLOVÁ M., DROBNÍK J., RÁMEK B. and KVÉTINA J. - Biodistribution of trans-1,2-diaminocyclohexane-trimetallito-platinum(II) attached to macromolecular carriers. I. Poly(hydroxyethyl-D,L-asparagine) carrier. -J. Cont. Rel., 17, 89-98, 1991.
-
(1991)
J. Cont. Rel.
, vol.17
, pp. 89-98
-
-
Filipová-Voprálová, M.1
Drobník, J.2
Rámek, B.3
Kvétina, J.4
-
127
-
-
0000069622
-
Cis-diaminedichtoroplatinum(II) complexes reversibly bound to water-soluble polyaspartamide carriers for chemotherapeutic applications. II. Platinum coordination to ethylenediamine ligands attached to poly(ethylene oxide)-grafted carrier polymers
-
NEUSE E.W., CALDWELL G. and PERLWITZ A.G. - Cis-diaminedichtoroplatinum(II) complexes reversibly bound to water-soluble polyaspartamide carriers for chemotherapeutic applications. II. Platinum coordination to ethylenediamine ligands attached to poly(ethylene oxide)-grafted carrier polymers. - J. Inorg. Organomet. Polymers, 5, 195-207, 1995.
-
(1995)
J. Inorg. Organomet. Polymers
, vol.5
, pp. 195-207
-
-
Neuse, E.W.1
Caldwell, G.2
Perlwitz, A.G.3
-
128
-
-
84985357028
-
Macromolecular metal compounds in cancer research : Concepts and synthetic approaches
-
NEUSE E.W. - Macromolecular metal compounds in cancer research : concepts and synthetic approaches. - Macromol. Symp., 80, 111-128, 1994.
-
(1994)
Macromol. Symp.
, vol.80
, pp. 111-128
-
-
Neuse, E.W.1
-
129
-
-
84989591463
-
Monoamineplatinum(II) complexes conjugated to water soluble carrier polymers for chemotherapeutic applications
-
MBONYANA C.W.N., NEUSE E.W. and PERLWITZ A.G. - Monoamineplatinum(II) complexes conjugated to water soluble carrier polymers for chemotherapeutic applications. - Applied Organometallic Chemistry, 7, 279-288, 1993.
-
(1993)
Applied Organometallic Chemistry
, vol.7
, pp. 279-288
-
-
Mbonyana, C.W.N.1
Neuse, E.W.2
Perlwitz, A.G.3
-
130
-
-
0000069622
-
Cis-diaminechloroplatinum (II) complexes reversibly bound to water soluble polyaspartamides for chemotherapeutic applications. Platinum coordination to ethylenediamine ligands attached to poly(ethylene oxide)-grafted carrier polymers
-
NEUSE W., CALDWELL G. and PERLWITZ A.G. - Cis-diaminechloroplatinum (II) complexes reversibly bound to water soluble polyaspartamides for chemotherapeutic applications. Platinum coordination to ethylenediamine ligands attached to poly(ethylene oxide)-grafted carrier polymers.- J. Inorg. and Organometallic Polymers, 5, 195-207 1995.
-
(1995)
J. Inorg. and Organometallic Polymers
, vol.5
, pp. 195-207
-
-
Neuse, W.1
Caldwell, G.2
Perlwitz, A.G.3
-
131
-
-
0028409718
-
Synthesis and antitumour activity of polyanion-Pt-complexes containing alicyclic amines as ligands
-
HAN M.J., PARK S.J., CHO T.J., CHANG J.Y., SOHN Y.S., LEE C.O. and CHOI S.U. - Synthesis and antitumour activity of polyanion-Pt-complexes containing alicyclic amines as ligands.-J. Bioact. Compat. Polymers, 9, 142-151, 1994.
-
(1994)
J. Bioact. Compat. Polymers
, vol.9
, pp. 142-151
-
-
Han, M.J.1
Park, S.J.2
Cho, T.J.3
Chang, J.Y.4
Sohn, Y.S.5
Lee, C.O.6
Choi, S.U.7
-
132
-
-
7444272275
-
A novel polymeric platinum(II) anticancer agent K1 30606. Preclinical studies of a water soluble polyphosphazene-Pt(DACH) conjugate
-
Amsterdam
-
SOHN Y. S., BAEK H., CHO Y. H., LEE Y.-A., JUNG O.-S., LEE C. O. and KIM Y. S. - A novel polymeric platinum(II) anticancer agent K1 30606. Preclinical studies of a water soluble polyphosphazene-Pt(DACH) conjugate. - Proc. of EORTC/NCI, Amsterdam, 1996.
-
(1996)
Proc. of EORTC/NCI
-
-
Sohn, Y.S.1
Baek, H.2
Cho, Y.H.3
Lee, Y.-A.4
Jung, O.-S.5
Lee, C.O.6
Kim, Y.S.7
-
133
-
-
0030062240
-
An adduct of cis-diammiedichloroplatinum(II) and poly(ethylene glycol)poly(L-lysine)-succinate : Synthesis and cytotoxic properties
-
BOGDANOV A.A. Jr, MARTIN C., BOGDANOVA A.V., BRADY T.J. and WEISSLEDER R. - An adduct of cis-diammiedichloroplatinum(II) and poly(ethylene glycol)poly(L-lysine)-succinate : synthesis and cytotoxic properties. - Bioconjugate Chem., 7, 144-149, 1996.
-
(1996)
Bioconjugate Chem.
, vol.7
, pp. 144-149
-
-
Bogdanov Jr., A.A.1
Martin, C.2
Bogdanova, A.V.3
Brady, T.J.4
Weissleder, R.5
-
134
-
-
0009949329
-
GB-21 a novel polymer complex with antitumouractivity in human renal and mammary xenografts
-
FIEBIG H.H., DREES M., RUHNAU T., MISRA H.K., ANDRUUS P. and HENDRlCKS H.R. - GB-21 a novel polymer complex with antitumouractivity in human renal and mammary xenografts. - Proc. Am. Soc. Cancer Res., 37, 297, 1996.
-
(1996)
Proc. Am. Soc. Cancer Res.
, vol.37
, pp. 297
-
-
Fiebig, H.H.1
Drees, M.2
Ruhnau, T.3
Misra, H.K.4
Andruus, P.5
Hendrlcks, H.R.6
-
135
-
-
0027427932
-
New cisplatin analogues in development, A review
-
WEISS R.B. and CHRISTIAN M.C. - New cisplatin analogues in development, A review. - Drugs, 46, 360-377, 1993.
-
(1993)
Drugs
, vol.46
, pp. 360-377
-
-
Weiss, R.B.1
Christian, M.C.2
-
136
-
-
0027982957
-
Polymers for delivering peptides and proteins
-
BURNHAM N.L. - Polymers for delivering peptides and proteins. - Am. J. Hosp. Pharm., 51, 210-218, 1994.
-
(1994)
Am. J. Hosp. Pharm.
, vol.51
, pp. 210-218
-
-
Burnham, N.L.1
-
137
-
-
0027253357
-
The conjugation of proteins with polyethylene glycol and other polymers
-
KATRE N.V. - The conjugation of proteins with polyethylene glycol and other polymers. - Adv. Drug Del. Rev., 10, 91-114, 1993.
-
(1993)
Adv. Drug Del. Rev.
, vol.10
, pp. 91-114
-
-
Katre, N.V.1
-
139
-
-
0002196524
-
Polymer conjugated macromolecular drugs for tumour-specific targeting
-
A.J. Domb Ed., John Wiley & Sons Ltd., New York
-
MAEDA H. - Polymer conjugated macromolecular drugs for tumour-specific targeting. - In : Polymer Site-Specific Pharmacotherapy, A.J. Domb Ed., John Wiley & Sons Ltd., New York, 1994, pp. 95-116.
-
(1994)
Polymer Site-Specific Pharmacotherapy
, pp. 95-116
-
-
Maeda, H.1
-
141
-
-
7444258812
-
-
Solubilisation of immunotoxins for pharmaceutical compositions using polymer conjugation. - US Patent, 4,917,888, 1990
-
KATRE N.V. and KNAUF M.J. - Solubilisation of immunotoxins for pharmaceutical compositions using polymer conjugation. - US Patent, 4,917,888, 1990.
-
-
-
Katre, N.V.1
Knauf, M.J.2
-
142
-
-
0027536607
-
L-asparaginase and PEG-asparaginase - Past, present and future
-
KEATING M.J., HOLMES R., LERNER S. and HO D.H. - L-asparaginase and PEG-asparaginase - past, present and future. - Leukemia Lymphoma, 10, 153-157, 1993.
-
(1993)
Leukemia Lymphoma
, vol.10
, pp. 153-157
-
-
Keating, M.J.1
Holmes, R.2
Lerner, S.3
Ho, D.H.4
-
143
-
-
0021056212
-
Potential use of an asparaginase-dextran conjugate in acute lymphoblastic leukæmia
-
WILEMAN T.E., BENNETT M. and LILLEYMANN J. - Potential use of an asparaginase-dextran conjugate in acute lymphoblastic leukæmia. - J. Pharm. Pharmacol., 35, 762-765, 1983.
-
(1983)
J. Pharm. Pharmacol.
, vol.35
, pp. 762-765
-
-
Wileman, T.E.1
Bennett, M.2
Lilleymann, J.3
-
144
-
-
0023755426
-
Use of polyethylene glycol-modified uricase (PEG-uricase) to treat hyperuricemia inpatient with non-Hodgkin lymphoma
-
CHUA C.C., GREENBERG M.L., VIAU A.T., NUCCI M., BRENCKMAN W.D. and HERSHFIELD M.S. - Use of polyethylene glycol-modified uricase (PEG-uricase) to treat hyperuricemia inpatient with non-Hodgkin lymphoma. - Annals Int. Med., 109 (2), 114-117, 1988.
-
(1988)
Annals Int. Med.
, vol.109
, Issue.2
, pp. 114-117
-
-
Chua, C.C.1
Greenberg, M.L.2
Viau, A.T.3
Nucci, M.4
Brenckman, W.D.5
Hershfield, M.S.6
-
145
-
-
0025181633
-
Alteration of biopharmaceutical properties of drugs by their conjugation with water-soluble macromolecules : Uricase-dextran conjugate
-
FUJITA T., YASUDA Y., TAKAKURA Y., HASHIDA M. and SEZAKI H. - Alteration of biopharmaceutical properties of drugs by their conjugation with water-soluble macromolecules : uricase-dextran conjugate. - J. Cont. Rel., 11, 149-156, 1990.
-
(1990)
J. Cont. Rel.
, vol.11
, pp. 149-156
-
-
Fujita, T.1
Yasuda, Y.2
Takakura, Y.3
Hashida, M.4
Sezaki, H.5
-
146
-
-
0021132808
-
Cancer therapy with chemically modified enzymes. II. The therapeutic effectiveness of arginase and arginase modified by covalent attachment of polyethylene glycol, on the Taper liver tumour and the L5178Y murine leukæmia
-
SAVOCA K.V., DAVIS F.F., VAN ES T.T., McCOY J.R. and PALCZUK N.C. - Cancer therapy with chemically modified enzymes. II. The therapeutic effectiveness of arginase and arginase modified by covalent attachment of polyethylene glycol, on the Taper liver tumour and the L5178Y murine leukæmia. - Cancer Biochem. Biophys., 7, 261-268, 1984.
-
(1984)
Cancer Biochem. Biophys.
, vol.7
, pp. 261-268
-
-
Savoca, K.V.1
Davis, F.F.2
Van Es, T.T.3
McCoy, J.R.4
Palczuk, N.C.5
-
147
-
-
0022851668
-
Chemical modification of tryptophanase from E. coli with polyethylene glycol to reduce its immunoreactivity towards antitryptophanase antibodies
-
YOSHIMOTO T., CHAO S.G., SAITO Y., IMAMURA I., WADA H. and INADA Y. - Chemical modification of tryptophanase from E. coli with polyethylene glycol to reduce its immunoreactivity towards antitryptophanase antibodies. - Enzyme, 36, 261, 1986.
-
(1986)
Enzyme
, vol.36
, pp. 261
-
-
Yoshimoto, T.1
Chao, S.G.2
Saito, Y.3
Imamura, I.4
Wada, H.5
Inada, Y.6
-
148
-
-
0019818287
-
Immunosupressive properties and circulatory life of achromobacter glutaminase-asparaginase covalently attached to polyethylene glycol in man
-
ABUCHOWSKI A., DAVIS F.F. AND DAVIS S. - Immunosupressive properties and circulatory life of achromobacter glutaminase-asparaginase covalently attached to polyethylene glycol in man. - Cancer Treat. Rep., 65, 1077-1081, 1981.
-
(1981)
Cancer Treat. Rep.
, vol.65
, pp. 1077-1081
-
-
Abuchowski, A.1
Davis, F.F.2
Davis, S.3
-
149
-
-
0018801628
-
Some properties of polyethylene glycol : Phenylalamine ammonia-lyase adducts
-
WIEDER K.J., PALCZUK N.C., VAN ES T. and DAVIS F.F. - Some properties of polyethylene glycol : phenylalamine ammonia-lyase adducts. - J. Biol. Chem., 254, 12579-12587, 1979.
-
(1979)
J. Biol. Chem.
, vol.254
, pp. 12579-12587
-
-
Wieder, K.J.1
Palczuk, N.C.2
Van Es, T.3
Davis, F.F.4
-
150
-
-
0026061242
-
A Phase I study including pharmacokinetics of polyethylene glycol conjugated interleukin-2
-
MEYERS F.J., PARADISE C., SCUDDER S.A., GOODMAN S.A. and KONRAD M. - A Phase I study including pharmacokinetics of polyethylene glycol conjugated interleukin-2. - Clin. Pharmacol. Ther., 49, 307-313, 1991.
-
(1991)
Clin. Pharmacol. Ther.
, vol.49
, pp. 307-313
-
-
Meyers, F.J.1
Paradise, C.2
Scudder, S.A.3
Goodman, S.A.4
Konrad, M.5
-
151
-
-
7444271221
-
Effects of the in vivo administration of pegylated recombinant human megakaryocyte growth and development factor (MGDF) in patients with advanced cancer
-
March 12-15, Amsterdam
-
CEBON J., BASSER R., CLARKE K., FOX R., GREEN M., CHIPMAN M., ZALCBERG J., MARTY J., MECHACA D., SHERIDAN W. AND BEGLEY G. - Effects of the in vivo administration of pegylated recombinant human megakaryocyte growth and development factor (MGDF) in patients with advanced cancer. - Proc. 9th NCI-EORTC Symp. on New Drugs in Cancer Therapy, March 12-15, Amsterdam, p. 202, 1996.
-
(1996)
Proc. 9th NCI-EORTC Symp. on New Drugs in Cancer Therapy
, pp. 202
-
-
Cebon, J.1
Basser, R.2
Clarke, K.3
Fox, R.4
Green, M.5
Chipman, M.6
Zalcberg, J.7
Marty, J.8
Mechaca, D.9
Sheridan, W.10
Begley, G.11
-
152
-
-
0028933704
-
Polyethylene glycol modification of interleukin-6 enhances its thrombopoietic activity
-
TSUTSUMI Y., TETSUNARI K., TSUNODA S.-I., OKADA N., KANEDA Y., OHSUGI Y., MIYAKE M., NAKAGAWA N. and MAYUMI T. - Polyethylene glycol modification of interleukin-6 enhances its thrombopoietic activity. - J. Cont. Rel., 33, 447-451, 1995.
-
(1995)
J. Cont. Rel.
, vol.33
, pp. 447-451
-
-
Tsutsumi, Y.1
Tetsunari, K.2
Tsunoda, S.-I.3
Okada, N.4
Kaneda, Y.5
Ohsugi, Y.6
Miyake, M.7
Nakagawa, N.8
Mayumi, T.9
-
153
-
-
7444248715
-
-
Polyoxymethylene-oxyethylene copolymers in conjugation with biomolecules. - US Patent, 5,476,653, 1995
-
PITT C.G. and HENDREN W. - Polyoxymethylene-oxyethylene copolymers in conjugation with biomolecules. - US Patent, 5,476,653, 1995.
-
-
-
Pitt, C.G.1
Hendren, W.2
-
154
-
-
0026705718
-
Polyethylene glycol (PEG)-modified granulocyte-macrophage colony-stimulating factor (GM-CSF) with conserved biological activity
-
MALIK F., DELGADO C., KNÜSLI C., IRVINE A.E., FISHER D. and FRANCIS G.E. - Polyethylene glycol (PEG)-modified granulocyte-macrophage colony-stimulating factor (GM-CSF) with conserved biological activity. - Exp. Hematol., 20, 1028-1035, 1992.
-
(1992)
Exp. Hematol.
, vol.20
, pp. 1028-1035
-
-
Malik, F.1
Delgado, C.2
Knüsli, C.3
Irvine, A.E.4
Fisher, D.5
Francis, G.E.6
-
155
-
-
0025893378
-
Pharmacokinetics of recombinant human granulocyte colony-stimulating factor conjugated to polyethylene glycol in rats
-
TANAKA H., SATEKE-ISHIKAWA R., ISHIKAWA M., MATSUKI S. and ASANO K. - Pharmacokinetics of recombinant human granulocyte colony-stimulating factor conjugated to polyethylene glycol in rats. - Cancer Res., 51, 3710-3714, 1991.
-
(1991)
Cancer Res.
, vol.51
, pp. 3710-3714
-
-
Tanaka, H.1
Sateke-Ishikawa, R.2
Ishikawa, M.3
Matsuki, S.4
Asano, K.5
-
156
-
-
0027504119
-
Polyethylene glycol-modified chimeric toxin composed of transforming growth factor a and Pseudomonas exotoxin
-
WANG Q.-C., PAI LH., DEBINSKI W., FITZ GERALD D.J. and PASTAN I. - Polyethylene glycol-modified chimeric toxin composed of transforming growth factor a and Pseudomonas exotoxin. - Cancer Res., 53, 4588-4594, 1993.
-
(1993)
Cancer Res.
, vol.53
, pp. 4588-4594
-
-
Wang, Q.-C.1
Pai, L.H.2
Debinski, W.3
Fitz Gerald, D.J.4
Pastan, I.5
-
157
-
-
0027686737
-
Synthesis of a MDP analogue/chitin conjugate that stimulates cultured macrophages
-
OHYA Y., MURATA J.-I., NISHIMOTO T. and OUCHI T. - Synthesis of a MDP analogue/chitin conjugate that stimulates cultured macrophages. - J. Bioact. Compat. Polymers, 8, 351-364, 1993.
-
(1993)
J. Bioact. Compat. Polymers
, vol.8
, pp. 351-364
-
-
Ohya, Y.1
Murata, J.-I.2
Nishimoto, T.3
Ouchi, T.4
-
158
-
-
0027625576
-
Inhibition of tumour metastasis by a synthetic polymer containing a cell-adhesive RGDS peptide
-
KOMAZAWA H., SAIKI I., IGARASHI Y., AZUMA I., KOJIMA M., ORIKASA A., ONO M. and ITOH I. - Inhibition of tumour metastasis by a synthetic polymer containing a cell-adhesive RGDS peptide. - J. Bioact. Compat. Pol., 8, 258-274, 1993.
-
(1993)
J. Bioact. Compat. Pol.
, vol.8
, pp. 258-274
-
-
Komazawa, H.1
Saiki, I.2
Igarashi, Y.3
Azuma, I.4
Kojima, M.5
Orikasa, A.6
Ono, M.7
Itoh, I.8
-
159
-
-
0029595445
-
Amino-acids and peptides. 26. Laminin-related peptide poly(ethylene glycol) hybrids and their inhibitory effect on experimental metastasis
-
KAWASAKI K., NAMIKAWA M., MIZUTA T., INOUE S., MAEDA M. and KAKIUCHI M. - Amino-acids and peptides. 26. Laminin-related peptide poly(ethylene glycol) hybrids and their inhibitory effect on experimental metastasis. - Biol. Pharm. J., 18 (12), 1714-1717, 1995.
-
(1995)
Biol. Pharm. J.
, vol.18
, Issue.12
, pp. 1714-1717
-
-
Kawasaki, K.1
Namikawa, M.2
Mizuta, T.3
Inoue, S.4
Maeda, M.5
Kakiuchi, M.6
-
160
-
-
0026124772
-
The therapeutic value of poly(ethylene glycol) modified proteins
-
NUCCI M.L., SHORR R. and ABUCHOWSKI A. -The therapeutic value of poly(ethylene glycol) modified proteins. - Adv. Drug Delivery Rev., 6, 133-151, 1991.
-
(1991)
Adv. Drug Delivery Rev.
, vol.6
, pp. 133-151
-
-
Nucci, M.L.1
Shorr, R.2
Abuchowski, A.3
-
161
-
-
0025125916
-
Biochemical and biopharmaceutical properties of macromolecular conjugates of uricase with dextran and polyethylene glycol
-
YASUDA Y., FUJITA T., TAKAKURA Y., HASHIDA M. and SEZAKI H. - Biochemical and biopharmaceutical properties of macromolecular conjugates of uricase with dextran and polyethylene glycol. - Chem. Pharm. Bull, 38 (7), 2053-2056, 1990.
-
(1990)
Chem. Pharm. Bull
, vol.38
, Issue.7
, pp. 2053-2056
-
-
Yasuda, Y.1
Fujita, T.2
Takakura, Y.3
Hashida, M.4
Sezaki, H.5
-
162
-
-
0023224937
-
Local and systematic effects during interleukin-2 therapy of murine mammary tumours
-
VAAGE J. - Local and systematic effects during interleukin-2 therapy of murine mammary tumours. - Cancer Res., 47, 4269-4298, 1987.
-
(1987)
Cancer Res.
, vol.47
, pp. 4269-4298
-
-
Vaage, J.1
-
163
-
-
0023115642
-
A progress report on the treatment of 157 patients with advanced cancer using lymphokine-activated killer cells and interleukin-2 or high dose interleukin-2 alone
-
ROSENBERG S.A., LOTZE M.T., MUUL L.M., CHANG A.E., AVIS F.P., LEITMAN S., LINEHAN W.M., ROBERTSON C.N., LEE R.E., RUBIN J.T., SEIPP C.A., SIMPSON C.G. and WHITE D.E. -A progress report on the treatment of 157 patients with advanced cancer using lymphokine-activated killer cells and interleukin-2 or high dose interleukin-2 alone. - N. Engl. J. Med., 316, 889-897, 1987.
-
(1987)
N. Engl. J. Med.
, vol.316
, pp. 889-897
-
-
Rosenberg, S.A.1
Lotze, M.T.2
Muul, L.M.3
Chang, A.E.4
Avis, F.P.5
Leitman, S.6
Linehan, W.M.7
Robertson, C.N.8
Lee, R.E.9
Rubin, J.T.10
Seipp, C.A.11
Simpson, C.G.12
White, D.E.13
-
164
-
-
0023683508
-
Relationship effective molecular size to systematic clearance in rats of recombinant interleukin-2 chemically modified with water-soluble polymers
-
KNAUF M.J., BELL D.P., HIRTZER P., LUO Z.-P., YOUNG J.D. and KATRE N.V. - Relationship effective molecular size to systematic clearance in rats of recombinant interleukin-2 chemically modified with water-soluble polymers - J. Biol. Chem., 263 (29), 15064-15070, 1988.
-
(1988)
J. Biol. Chem.
, vol.263
, Issue.29
, pp. 15064-15070
-
-
Knauf, M.J.1
Bell, D.P.2
Hirtzer, P.3
Luo, Z.-P.4
Young, J.D.5
Katre, N.V.6
-
165
-
-
0024388928
-
Shedule dependency of antitumour activity and toxicity of polyethylene glycol-modified interleukin-2 in murine tumour models
-
ZIMMERMAN R.J., AUKERMAN S.L., KATRE N.V., WINKELHAKE J.L. and YOUNG J.D.-Shedule dependency of antitumour activity and toxicity of polyethylene glycol-modified interleukin-2 in murine tumour models. - Cancer Res., 49, 6521 - 6528, 1989.
-
(1989)
Cancer Res.
, vol.49
, pp. 6521-6528
-
-
Zimmerman, R.J.1
Aukerman, S.L.2
Katre, N.V.3
Winkelhake, J.L.4
Young, J.D.5
-
166
-
-
0025308898
-
The colony-stimulating factors : Discovery, development and clinical applications
-
METCALF D. - The colony-stimulating factors : discovery, development and clinical applications. - Cancer, 65, 2185-2195, 1990.
-
(1990)
Cancer
, vol.65
, pp. 2185-2195
-
-
Metcalf, D.1
-
169
-
-
0025832801
-
Targetable photoactivatable polymeric drugs
-
KOPECEK J., RIHOVA B. and KRINICK N. - Targetable photoactivatable polymeric drugs. - J. Cont. Rel., 16, 137-44, 1991.
-
(1991)
J. Cont. Rel.
, vol.16
, pp. 137-144
-
-
Kopecek, J.1
Rihova, B.2
Krinick, N.3
-
170
-
-
0028248444
-
A polymeric delivery system for the simultaneous delivery of drugs activatable by enzymes and/or light
-
KRINICK N.L., SUN Y., JOYNER D., SPIKES J.D., STRAIGHT R.C. and KOPECEK J. - A polymeric delivery system for the simultaneous delivery of drugs activatable by enzymes and/or light. - J. Biomat. Sci., Polymer Ed., 5, 303-324, 1994.
-
(1994)
J. Biomat. Sci., Polymer Ed.
, vol.5
, pp. 303-324
-
-
Krinick, N.L.1
Sun, Y.2
Joyner, D.3
Spikes, J.D.4
Straight, R.C.5
Kopecek, J.6
-
171
-
-
21344480665
-
Synthesis and photoproperties of a substituted phthalocyanine-N-(2-hydroxypropyl)methacrylamide copolymer conjugate
-
GU Z.W., SPIKES J.D., KOPECKOVA P. and KOPECEK J. - Synthesis and photoproperties of a substituted phthalocyanine-N-(2-hydroxypropyl)methacrylamide copolymer conjugate. - Coll. Czech Chem. Comm., 58, 2321-2336, 1993.
-
(1993)
Coll. Czech Chem. Comm.
, vol.58
, pp. 2321-2336
-
-
Gu, Z.W.1
Spikes, J.D.2
Kopeckova, P.3
Kopecek, J.4
-
172
-
-
0001095828
-
6 conjugates and a preliminary study of their photodynamic effect on mouse splenocytes in vitro
-
6 conjugates and a preliminary study of their photodynamic effect on mouse splenocytes in vitro. - Makromol. Chem., 191, 839-856, 1990.
-
(1990)
Makromol. Chem.
, vol.191
, pp. 839-856
-
-
Krinick, N.L.1
Rihova, B.2
Ulbrich, K.3
Strohalm, J.4
Kopecek, J.5
-
173
-
-
0027253329
-
6 towards human hepatocarcinoma cell-line (PLC/PRF/5) targeted with galactosamine and to mouse splenocytes targeted with anti-Thy 1.2 antibodies
-
6 towards human hepatocarcinoma cell-line (PLC/PRF/5) targeted with galactosamine and to mouse splenocytes targeted with anti-Thy 1.2 antibodies. -J. Cont. Rel. 25, 71-87, 1993.
-
(1993)
J. Cont. Rel.
, vol.25
, pp. 71-87
-
-
Rihova, B.1
Krinick, N.L.2
Kopecek, J.3
-
174
-
-
0028935989
-
Assessment of myocardial perfusion using contrast-enhanced MR imaging : Current status and future developments
-
MUHLER A. - Assessment of myocardial perfusion using contrast-enhanced MR imaging : current status and future developments. - Magma, 3, 21-33, 1995.
-
(1995)
Magma
, vol.3
, pp. 21-33
-
-
Muhler, A.1
-
176
-
-
0019884074
-
Pinocytic uptake and intracellular degradation of N-(2-hydroxypropyl)methacrylamide copolymers. A potential drug delivery system
-
DUNCAN R., REJMANOVA P., KOPECEK J. and LLOYD J.B.-Pinocytic uptake and intracellular degradation of N-(2-hydroxypropyl)methacrylamide copolymers. A potential drug delivery system. -Biochim. Biophys. Acta, 678, 143-150, 1981.
-
(1981)
Biochim. Biophys. Acta
, vol.678
, pp. 143-150
-
-
Duncan, R.1
Rejmanova, P.2
Kopecek, J.3
Lloyd, J.B.4
-
177
-
-
0027831928
-
Targeting of N-(2-hydroxypropyl)methacrylamide copolymer-doxorubicin conjugate to the hepatocyte galactose-receptor in mice : Visualisation and quantification by gamma scintigraphy as a basis for clinical targeting studies
-
PIMM M.V., PERKINS A.C., DUNCAN R. and ULBRICH K.-Targeting of N-(2-hydroxypropyl)methacrylamide copolymer-doxorubicin conjugate to the hepatocyte galactose-receptor in mice : visualisation and quantification by gamma scintigraphy as a basis for clinical targeting studies. - J. Drug Targeting, 1, 125-131, 1993.
-
(1993)
J. Drug Targeting
, vol.1
, pp. 125-131
-
-
Pimm, M.V.1
Perkins, A.C.2
Duncan, R.3
Ulbrich, K.4
-
178
-
-
0029662276
-
123I-labelled N-(2-hydroxypropyl)methacrylamide-doxorubicin in mice bearing transplanted melanoma and mammary carcinoma
-
123I-labelled N-(2-hydroxypropyl)methacrylamide-doxorubicin in mice bearing transplanted melanoma and mammary carcinoma.-J. Drug Targeting, 3, 385-390, 1996.
-
(1996)
J. Drug Targeting
, vol.3
, pp. 385-390
-
-
Pimm, M.1
Perkins, A.2
Duncan, R.3
Ulbrich, K.4
Strohalm, J.5
-
179
-
-
0028065153
-
Inversion recovery EPI of bolus transit in rat myocardium using intravascular and extravascular gadolinium-based MR contrast media : Dose effects on peak signal enhancement
-
WENDLAND M.F., SAEED M., YU K.K., ROBERTS T.P.L., LAUERMA K., DERUGIN N., VARADARAJAN J., WATSON A.D. and HIGGINS C.B. - Inversion recovery EPI of bolus transit in rat myocardium using intravascular and extravascular gadolinium-based MR contrast media : dose effects on peak signal enhancement. - Magn. Reson. Med., 32, 319-329, 1994.
-
(1994)
Magn. Reson. Med.
, vol.32
, pp. 319-329
-
-
Wendland, M.F.1
Saeed, M.2
Yu, K.K.3
Roberts, T.P.L.4
Lauerma, K.5
Derugin, N.6
Varadarajan, J.7
Watson, A.D.8
Higgins, C.B.9
-
180
-
-
0027960717
-
Synthetic copolymer kit for radionuclide blood-pool imaging
-
BOGDANOV A.A., CALLAHAN R.J., WILKINSON R.A., MARTIN C. and CAMERON J. A. - Synthetic copolymer kit for radionuclide blood-pool imaging.-J. Nucl. Med., 35, 1880-1886, 1994.
-
(1994)
J. Nucl. Med.
, vol.35
, pp. 1880-1886
-
-
Bogdanov, A.A.1
Callahan, R.J.2
Wilkinson, R.A.3
Martin, C.4
Cameron, J.A.5
-
181
-
-
0028794979
-
MR lymphography with a lymphotic T1 - Type MR contrast agent : Gd-DPTA-PGM
-
HARIKA L., WEISSLEDER R., POSS K., ZIMMER C., PAPISOV M. I. and BRADY T. J. - MR lymphography with a lymphotic T1 - type MR contrast agent : Gd-DPTA-PGM. - Magn. Reson. Med., 33, 88-92, 1995.
-
(1995)
Magn. Reson. Med.
, vol.33
, pp. 88-92
-
-
Harika, L.1
Weissleder, R.2
Poss, K.3
Zimmer, C.4
Papisov, M.I.5
Brady, T.J.6
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