L-arginine prevents bone loss and bone collagen breakdown in cyclosporin A-treated rats

European Journal of Pharmacology

Volumn 408, Issue 3, 2000, Pages 323-326

  Fiore, Carmelo E ^a   Pennisi, Pietra ^a   Cutuli, Vincenza Maria ^a   Prato, Agata ^a   Messina, Rossella ^a   Clementi, Giuseppe ^a  

^a UNIVERSITY OF CATANIA   (Italy)

Author keywords

Arginine; Cyclosporin A; Osteopenia; Pyridinoline; Rat

Indexed keywords

ALKALINE PHOSPHATASE; ARGININE; COLLAGEN; CYCLOSPORIN A; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE; PYRIDINOLINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BONE ATROPHY; BONE MINERAL; CONTROLLED STUDY; DRUG TOXICITY; FEMUR; MALE; NONHUMAN; OSTEOLYSIS; OSTEOPENIA; PRIORITY JOURNAL; RAT;

AMINO ACIDS; ANIMALS; ARGININE; BODY WEIGHT; BONE AND BONES; BONE DENSITY; COLLAGEN; CYCLOSPORINE; MALE; NG-NITROARGININE METHYL ESTER; RATS; RATS, SPRAGUE-DAWLEY;

EID: 0034711595     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(00)00800-1     Document Type: Article

References (13)

1. L-arginine and allopurinol protect against cyclosporine nephrotoxicity
2. Raloxifene analog (LY117018HCL) ameliorates cyclosporin A-induced osteopenia in oophorectomized rats
3. The deleterious effects of long-term cyclosporin A, cyclosporin G, and FK506 on bone mineral metabolism in vivo
4. Nitric oxide modulates fracture healing
5. Skeletal effects of low-dose cyclosporin A in aged male rats: lack of relationship to serum testosterone levels
6. Nitric oxide and bone
7. Intermittent use of nitrates increases bone mineral density: the study of osteoporotic fractures
8. Cyclosporin A in the oophorectomized rat: unexpected severe bone resorption
9. Role of nitric oxide in cyclosporine A-induced hypertension
10. Cyclosporin A suppresses the induction of nitric oxide synthesis in interferon-gamma-treated L929 fibroblasts
11. Serum pyridinoline as a specific marker of collagen breakdown on bone metabolism in hemodialysis patients
12. Nitric oxide donor alleviates ovariectomy-induced bone loss
13. Prevention of corticosteroid-induced bone loss with nitric oxide donor nitroglicerin in male rats