5-HT1A and 5-HT2A serotonin receptor turnover in adult rat offspring prenatally exposed to cocaine

Brain Research

Volumn 877, Issue 2, 2000, Pages 141-148

  Vicentic, Aleksandra ^a   Cabrera Vera, Theresa M ^a   Pinto, Wilfred ^a   Battaglia, George ^a  

^a LOYOLA UNIVERSITY CHICAGO   (United States)

Author keywords

EEDQ; Gestation; In utero; Prenatal; Receptor kinetics; Serotonin

Indexed keywords

2 ETHOXY 1(2H) QUINOLINECARBOXYLIC ACID ETHYL ESTER; COCAINE; SEROTONIN 1A RECEPTOR; SEROTONIN 2A RECEPTOR; SODIUM CHLORIDE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN CORTEX; CELL KINETICS; COCAINE DEPENDENCE; COGNITIVE DEFECT; CONTROLLED STUDY; FEMALE; HALF LIFE TIME; MALE; NEWBORN; NONHUMAN; PRENATAL EXPOSURE; PRIORITY JOURNAL; PROTEIN DEGRADATION; RAT; RECEPTOR DENSITY;

ANIMAL; ANIMALS, NEWBORN; CEREBRAL CORTEX; COCAINE; COCAINE-RELATED DISORDERS; FEMALE; NEURONS; PREGNANCY; PRENATAL EXPOSURE DELAYED EFFECTS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, SEROTONIN; RECOVERY OF FUNCTION; SUPPORT, U.S. GOV'T, NON-P.H.S.; SUPPORT, U.S. GOV'T, P.H.S.; TIME FACTORS;

EID: 0034703463     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(00)02668-8     Document Type: Article

References (61)

1. Akbari H.M., Kramer H.K., Whitaker-Azmitia P.M., Spear L.P., Azmitia E.C. Prenatal cocaine exposure disrupts the development of the serotonergic system. Brain Res. 572:(1-2):1992;57-63.
2. Arango V., Underwood M.D., Gubbi A.V., Mann J.J. Localized alterations in pre- and postsynaptic serotonin binding sites in the ventrolateral prefrontal cortex of suicide victims. Brain Res. 688:(1-2):1995;121-133.
3. 1A receptor-mediated neuroendocrine responses in male but not female rat progeny after prenatal cocaine: evidence for gender differences. J. Pharmacol. Exper. Ther. 271:(3):1994;1453-1461.
4. 2A receptor function in male and female rat offspring. Synapse. 35:(2):2000;163-172.
5. Battaglia G., Norman A.B., Creese I. Differential serotonin2 receptor recovery in mature and senescent rat brain after irreversible receptor modification: effect of chronic reserpine treatment. J. Pharmacol. Exper. Ther. 243:(1):1987;69-75.
6. Battaglia G., Norman A.B., Newton P.L., Creese I. In vitro and in vivo irreversible blockade of cortical S2 serotonin receptors by N-ethoxycarbonyl-2-dihydroquinoline (EEDQ): A technique for investigating S2 serotonin receptor recovery. J. Neurochem. 46:1986;589-593.
7. Battaglia G., Vicentic A., Kuhar M.J. Determination of 5-HT transporter turnover kinetics in 5-HT terminal fields: Effects of Maturation. Soc. Neurosci. Abstr. 25:(2):1999;1701.
8. Belej T., Manji D., Sioutis S., Barros H.M., Nobrega J.N. Changes in serotonin and norepinephrine uptake sites after chronic cocaine: pre- vs. post-withdrawal effects. Brain Res. 736:(1-2):1996;287-296.
9. Cabrera T.M., Levy A.D., Li Q., Van de Kar L.D., Battaglia G. Cocaine-induced deficits in ACTH and corticosterone responses in female rat progeny. Brain Res. Bull. 34:(2):1994;93-97.
10. Cabrera T.M., Yracheta J.M., Li Q., Levy A.D., Van de Kar L.D., Battaglia G. Prenatal cocaine produces deficits in serotonin mediated neuroendocrine responses in adult rat progeny: evidence for long-term functional alterations in brain serotonin pathways. Synapse. 15:(2):1993;158-168.
11. 1A binding in rat brain-a combined in situ hybridization/in vitro receptor autoradiographic study. Brain Res. 561:(1):1991;51-60.
12. 1A-mediated facilitation of in vivo acetylcholine release in rat frontal cortex. Brain Res. 707:(2):1996;320-323.
13. Cunningham K.A., Lakoski J.M. Electrophysiological effects of cocaine and procaine on dorsal raphe serotonin neurons. Eur. J. Pharmacol. 148:(3):1988;457-462.
14. Cunningham K.A., Lakoski J.M. The interaction of cocaine with serotonin dorsal raphe neurons. Single-unit extracellular recording studies. Neuropsychopharmacology. 3:(1):1990;41-50.
15. 1A receptors. Pharmacol. Biochem. Behav. 38:(2):1991;353-357.
16. Delaney-Black V., Covington C., Templin T., Ager J., Martier S., Sokol R. Prenatal cocaine exposure and child behavior. Pediatrics. 102:(4 Pt 1):1998;945-950.
17. Feuerstein T.J., Gleichauf O., Landwehrmeyer G.B. Modulation of cortical acetylcholine release by serotonin: the role of substance P interneurons. Naunyn-Schmiedeberg’s Arch. Pharmacol. 354:(5):1996;618-626.
18. 2 receptor-mediated adrenocorticotropin release in the rat: effect of repeated antidepressant treatments. Eur. J. Pharmacol. 221:(1):1992;27-33.
19. Glennon R.A. Serotonin receptors: clinical implications. Neurosci. Biobehav. Rev. 14:1990;35-47.
20. Glennon R.A., Dukat M. Serotonin receptor subtypes. Bloom F.E., Kupher (D.J. Psychopharmacology: the Fourth Generation of Progress. 1995;415-429 Raven Press, New York.
21. Gurevich E.V., Joyce J.N. Alterations in the cortical serotonergic system in schizophrenia: a postmortem study. Biol. Psych. 42:(7):1997;529-545.
22. 1A receptor agonists induce Fos protein expression in the locus coeruleus of the conscious rat. Brain Res. 759:(1):1997;156-159.
23. 2 sites in cortex and amygdala. Brain Res. 614:1993;37-44.
24. 2 receptors in rat brain: an autoradiographic study. Synapse. 14:(4):1993;324-331.
25. 1A receptors in the effects of acute chronic fluoxetine on extracellular serotonin in the frontal cortex. Pharmacol. Biochem. Behav. 54:(1):1996;143-147.
26. 2A receptors with carbon-11-MDL 100907. J. Nuc Med. 39:(1):1998;208-214.
27. 2A serotonin receptors in the primate cerebral cortex: possible site of action of hallucinogenic and antipsychotic drugs in pyramidal cell apical dendrites. Proc. Nat. Acad. Sci. USA. 95:(2):1998;735-740.
28. Koren G., Nulman I., Rovet J., Greenbaum R., Loebstein M., Einarson T. Long-term neurodevelopmental risks in children exposed in utero to cocaine: The Toronto adoption study. Ann. N.Y. Acad. Sci. 846:1998;306-313.
29. Kosofsky B.E., Wilkins A.S., Gressens P., Evrard P. Transplacental cocaine exposure: a mouse model demonstrating neuroanatomic and behavioral abnormalities. J. Child Neurol. 9:(3):1994;234-241.
30. 2A receptor and its mRNA in a subpopulation of rat striatal neurons. J. Neurosci. 16:(11):1996;3727-3736.
31. Lauder J.M. Ontogeny of of the serotonergic system in the rat:Serotonin as a developmental signal. Ann. NY. Acad. Sci. 600:1990;287-314.
32. Lester B.M., La Gasse L.L., Seifer R. Cocaine exposure and children: The meaning of subtle effects. Science. 282:1998;633-634.
33. Levy A.D., Li Q., Kerr J.E., Rittenhouse P.A., Milonas G., Cabrera T.M., Battaglia G., Alvarez Sanz M.C., Van de Kar L.D. Cocaine-induced elevation of plasma adrenocorticotropin hormone and corticosterone is mediated by serotonergic neurons. J. Pharmacol. Exper.Ther. 259:(2):1991;495-500.
34. Levy A.D., Bauman M.H., Van de Kar L.D. Monoaminergic regulation of neuroendocrine function and its modification by cocaine. Front. Neuroendocrinol. 15:1994;85-156.
35. Li M.Y., Yan Q.S., Coffey L.L., Reith M.E. Extracellular dopamine, norepinephrine, and serotonin in the nucleus accumbens of freely moving rats during intracerebral dialysis with cocaine and other monoamine uptake blockers. J. Neurochem. 66:(2):1996;559-568.
36. Li Q., Brownfield M.S., Battaglia G., Cabrera T.M., Levy A.D., Rittenhouse P.A., Van de Kar L.D. Long-term traetment with the antidepressants fluoxetine and desipramine potentiates endocrine responses to the serotonin agonists 6-chloro-2-[1-piperazinyl]-pyrazine (MK212) and 1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane HCl (DOI). J. Pharmacol. Exp Ther. 266:1993;836-844.
37. Lowry O.H., Rosebrough N.J., Farr A.L., Randall R.J. Protein measurements with the folin phenol reagent. J. Biol. Chem. 93:1951;265-275.
38. 1A receptors in guinea pig dentate gyrus. Brain Res. 761:(1):1997;105-112.
39. McBride W.J., Chernet E., Rabold J.A., Lumeng L., Li T.K. Serotonin-2 receptors in the CNS of alcohol-preferring and -nonpreferring rats. Pharmacol. Biochem. Behav. 46:(3):1993;631-636.
40. McBride W.J., Guan X.M., Chernet E., Lumeng L., Li T.K. Regional serotonin1A receptors in the CNS of alcohol-preferring and -nonpreferring rats. Pharmacol. Biochem. Behav. 49:(1):1994;7-12.
41. Meller E., Goldstein M., Friedhoff A.J., Schweitzer J.W. N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline (EEDQ): a new tool to probe CNS receptor function. Adv. Exper. Med. Biol. 235:1988;121-136.
42. Meyer J.S., Shearman L.P., Collins L.M. Monamine transporters and the neurobehavioral teratology of cocaine [Review]. Pharmacol. Biochem. Behav. 55:(4):1996;585-593.
43. Norman A.B., Battaglia G., Creese I. Differential recovery rates of rat D2 dopamine receptors as a function of aging and chronic reserpine treatment following irreversible modification: a key to receptor regulatory mechanisms. J. Neurosci. 7:(5):1987;1484-1491.
44. 1A receptors in rat hypothalamus and dentate gyrus after ’binge’ pattern cocaine administration. Synapse. 30:(2):1998;166-171.
45. Pinto W., Battaglia G. Comparative recovery kinetics of 5-hydroxytryptamine 1A, 1B, and 2A receptor subtypes in rat cortex after receptor inactivation: evidence for differences in receptor production and degradation. Mol. Pharm. 46:(6):1994;1111-1119.
46. Riley E.P., Lochry E.A., Shapiro N.R., Baldwin J. Response perseveration in rats exposed to alcohol prenatally. Pharmacol. Biochem. Behav. 10:1979;255-259.
47. Ritz M.C., Cone E.J., Kuhar M.J. Cocaine inhibition of ligand binding at dopamine, norepinephrine and serotonin transporters: a structure-activity study. Life Sci. 46:1990;635-645.
48. Roth B.L. Multiple serotonin receptors: clinical and experimental aspects. Ann. Clin. Psychiarty. 6:1994;67-78.
49. 2C): where structure meets function. Pharmacol. Ther. 79:1998;231-257.
50. Sladeczek F., Bockaert J. Turnover in vivo of α1-adrenergic receptors in rat submaxillary glands. Mol. Pharm. 23:1982;282-288.
51. Sleight A.J., Pierce P.A., Schmidt A.W., Hekmatpanah C.R., Peroutka S.J. Serotonin receptor subtypes. The Clinical Utility of Serotonin Receptor Active Agents in Neuropsychiatric Disease. 1991;211-227 Wiley -Liss, New York.
52. 2A receptor binding measured with positron emission tomography and [18F] altanserin in the human brain. Synapse. 30:(4):1998;380-392.
53. Spear L.P., Kirstein C.L., Frambes N.A. Cocaine effects on the developing central nervous system: behavioral, psychopharmacological, and neurochemical studies. Ann. N.Y. Acad. Sci. 562:1989;290-307.
54. Suehiro M., Underwood M., Arango V., Wang T.S., Kassir S., Bakalian M., Yatabe T., Pratap M., Van Heertum R.L., Mann J.J. In vivo biodistribution of a radiotracer for imaging serotonin-1A receptor sites with PET:[11C]LY274601. Life Sci. 63:(17):1998;1533-1542.
55. Teneud L.M., Baptista T., Murzi E., Hoebel B.G., Hernandez L. Systemic and local cocaine increase extracellular serotonin in the nucleus accumbens. Pharmacol. Biochem. Behav. 53:(3):1996;747-752.
56. 2 receptor mediated c-fos gene expression. Eur. J. Pharrm. 290:(3):1995;263-266.
57. Van de Kar L.D., Rittenhouse P.A., Palionis T., Brownfield M.S., Lent S.J., Carnes M., Bethea C.L. Effect of cocaine injections on the neuroendocrine response to the serotonin agonist MK-212. Biol. Psych. 32:(3):1992;258-269.
58. Vicentic A., Kuhar M.J., Battaglia G. Initial determination of 5-HT transporter turnover in dorsal versus median raphe nuclei: regional and maturational differences. Soc. Neurosci. Abstr. 25:(2):1999;1701.
59. Vogel G. Cocaine wreaks subtle damage on developing brains. Science. 278:1997;38-39.
60. Whitaker-Azmitia P.M., Druse M., Walker P., Lauder J.M. Serotonin as a developmental signal. Behav. Brain Res. 73:1996;19-29.
61. 2A receptors are expressed on pyramidal cells and interneurons in the rat cortex. Synapse. 27:(1):1997;79-82.