Changes in serotonin and norepinephrine uptake sites after chronic cocaine: Pre- vs. post-withdrawal effects

Brain Research

Volumn 736, Issue 1-2, 1996, Pages 287-296

  Belej, Timea ^a   Manji, Dilshad ^a   Sioutis, Susie ^a   Barros, Helena M T ^b   Nobrega, José N ^a  

^a CENTRE FOR ADDICTION AND MENTAL HEALTH   (Canada)

^b UNIVERSIDADE FEDERAL DE CIÊNCIAS DA SAÚDE DE PORTO ALEGRE   (Brazil)

Author keywords

autoradiography; hypothalamus; limbic forebrain; 3H cyanoimipramine; 3H nisoxetine

Indexed keywords

CIANOPRAMINE; COCAINE; NISOXETINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTORADIOGRAPHY; BINDING SITE; CONTROLLED STUDY; FEMALE; HYPOTHALAMUS; LIMBIC SYSTEM; NONHUMAN; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; RAT; SEROTONIN UPTAKE; WITHDRAWAL SYNDROME;

EID: 0030583644     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/0006-8993(96)00713-5     Document Type: Article

References (63)

1. 3H]GBR-12935 binding after chronic treatment with dopamine active drugs, Psychopharmacology, 102 (1990) 291-294.
2. [2] Baumann, M.H., Raley, T.S., Partilla, J.S. and Rothman, R.B., Biosynthesis of dopamine and serotonin in the rat brain after repeated cocaine injections: a microdissection mapping study, Synapse, 14 (1993) 40-50.
3. [3] Bechara, A., Harrington, F., Nader, K. and van der Kooy, D., Neurobiology of motivation: double dissociation of two motivational mechanisms mediating opiate reward in drug-naive versus drug-dependent animals, Behav. Neurosci., 106 (1992) 798-807.
4. [4] Benmansour, S., Tejani-Butt, S.M., Hauptmann, M. and Brunswick, D.J., Lack of effect of high-dose cocaine on monoamine uptake sites in rat brain measured by quantitative autoradiography, Psychopharmacology, 106 (1992) 459-462.
5. [5] Brunswick, D.J., Benmansour, S., Tejani-Butt, S.M. and Hauptmann, M., Effects of high-dose methamphetamine on monoamine uptake sites in rat brain measured by quantitative autoradiography, Synapse, 11 (1992) 287-293.
6. [6] Carroll, M.E., Lac. ST., Asencio, M. and Kragh, R., Fluoxetine reduces intravenous cocaine self-administration in rats, Pharmacol. Biochem. Behav., 35 (1990) 237-244.
7. [7] Cunningham, E.T. and Sawchenko, P.E., Anatomical specificity of noradrenergic inputs to the paraventricular and supraoptic nuclei of the rat hypothalamus, J. Comp. Neurol., 274 (1988) 60-76.
8. [8] Cunningham, K.A., Paris, J.M. and Goeders, N.E., Chronic cocaine enhances serotonin autoregulation and serotonin uptake binding, Synapse, 11 (1992) 112-123.
9. 3H-paroxetine-labeled serotonin uptake sites in rat brain, Synapse, 1 (1987) 488-496.
10. [10] Egan, M.F., Wing, L., Li, R., Kirch, D.G. and Wyatt, R.J., Effects of chronic cocaine treatment on rat brain: long-term reduction in frontal cortex serotonin, Biol. Psychiatry, 36 (1994) 637-640.
11. [11] Ellison, G., Continuous amphetamine and cocaine have similar neurotoxic effects in lateral habenular nucleus and fasciculus retroflexus, Brain Res., 598 (1992) 353-356.
12. [12] Ellison, G. and Switzer, R.C., Dissimilar patterns of degeneration in brain following four different addictive stimulants, Neuroreport, 5 (1993) 17-20.
13. [13] Gobbi, M., Cervo, L., Taddei, C. and Mennini, T., Autoradiographic localization of [3H]paroxetine specific binding in the rat brain, Neurochem. Int., 16 (1990) 247-251.
14. 3H]imipramine binding sites in rat brain by light microscopic autoradiography, Life Sci., 32 (1983) 2355-2361.
15. [15] Ikawa, K., Watanabe, A., Motohashi, N. and Kaneno, S., The effect of repeated administration of methamphetamine on dopamine uptake sites in rat striatum, Neurosci. Lett., 167 (1994) 37-40.
16. [16] Johnson, R.G., Fiorella, D. and Rabin, R.A., Effects of chronic cocaine administration on the serotonergic system in the rat brain, Pharmacol. Biochem. Behav., 46 (1993) 289-293.
17. [17] Kalivas, P.W. and Duffy, P., The effect of acute and daily cocaine treatment on extracellular dopamine in the nucleus accumbens, Synapse, 5 (1990) 48-58.
18. [18] Karoum, F., Suddath, R.L. and Wyatt, R.J., Chronic cocaine and rat brain catecholamines: long-term reduction in hypothalamic and frontal cortex dopamine metabolism, Eur. J. Pharmacol., 186 (1990) 1-8.
19. [19] Kleven, M.S., Woolverton, W.L. and Seiden, L.S., Lack of long-term monoamine depletions following repeated or continuous exposure to cocaine, Brain Res. Bull., 21 (1988) 233-237.
20. 3H]cyanoimipramine, Brain Res., 454 (1988) 78-88.
21. 3H]cyanoimipramine autoradiography, Brain Res., 505 (1989) 123-129.
22. [22] Kuhar, M.J., Molecular pharmacology of cocaine - a dopamine hypothesis and its implications. In Cocaine: Scientific and Social Dimensions, Ciba Foundation Symposium, 166, 1992, pp. 81-95.
23. [23] Kuhar, M.J., Ritz, M.C. and Boja, J.W., The dopamine hypothesis of the reinforcing properties of cocaine, Trends Neurosci., 14 (1991) 299-302.
24. [24] Leibowitz, S.F., Paraventricular nucleus: A primary site mediating adrenergic stimulation of feeding and drinking, Pharmacol. Biochem. Behav., 8 (1977) 163-175.
25. [25] Leibowitz, S.F., Neurochemical systems of the hypothalamus. Control of feeding and drinking behavior and water and electrolyte excretion. In P.J. Morgane and J. Panksepp (Eds.), Handbook of the Hypothalamus - Behavioral Studies of the Hypothalamus, Volume 3 - Part A, Marcel Dekker, 1980, pp. 299-438.
26. [26] Levy, A.D., Baumann, M.H. and Van de Kar, L.D., Monoaminergic regulation of neuroendocrine function and its modification by cocaine, Frontiers Neuroendocrinol., 15 (1994) 85-156.
27. [27] Liposits, Z., Phelix, C. and Paull, W.K., Adrenergic innervation of corticotropin releasing factor (CRF)-synthesizing neurons in the hypothalamic paraventricular nucleus of the rat. Histochemistry, 84 (1986), 201-205.
28. 3H]WIN-35428 binding sites in human striatum, Brain Res., 628 (1993) 17-25.
29. [29] Loh, E.A. and Roberts, D.C.S., Break points on a progressive ratio schedule reinforced by intravenous cocaine increases following depletion of forebrain serotonin, Pharmacol. Biochem. Behav., 101 (1990) 262-266.
30. [30] Lowenstein, D.H., Massa, S.M., Rosbotham, M.C., Collins, S.D., McKlnney, H.E. and Simon, R.P., Acute neurologic and psychiatric complications associated with cocaine abuse, Am. J. Med., 83 (1987) 841-846.
31. [31] McKellar, S. and Loewy, A.D., Organization of some brain stem afferents to the paraventricular nucleus of the hypothalamus in the rat, Brain Res., 217 (1981) 351-357.
32. 14C-2-deoxyglucose uptake after feeding-inducing intrahypothalamic norepinephrine injections, Brain Res. Bull., 24 (1990) 249-255.
33. [33] Parsons, L.H. and Justice, J.B., Serotonin and dopamine sensitization in the nucleus accumbens, ventral tegmental area, and dorsal raphe nucleus following repeated cocaine administration. J. Neurochem., 61 (1993) 1611-1619.
34. [34] Paxinos, G. and Watson, C., The Rat Brain in Stereotaxic Coordinates, Second Edition, Academic Press, Sydney, 1986.
35. [35] Pettit, H.O., Pan, H.-T., Parsons, L.H. and Justice, J.B. Jr., Extracellular concentrations of cocaine and dopamine are enhanced during chronic cocaine administration, J. Neurochem., 55 (1990) 798-804.
36. [36] Post, R.M., Cocaine psychosis: a continuum model, Am. J. Psychiatry, 132 (1975) 225-231.
37. [37] Post, R.M. and Kopanda, R.T., Cocaine, kindling and psychosis, Am. J. Psychiatry, 133 (1976) 627-634.
38. [38] Post, R.M., Weiss, S.R.B., Pert, A. and Uhde, T.W., Chronic-cocaine administration: sensitization and kindling effects. In S. Fisher et al. (Eds.), Cocaine: Clinical and Biobehavioral Aspects, Oxford Press, New York, 1987, pp. 109-173.
39. [39] Richardson, N.R. and Roberts, D.C.S., Fluoxetine pretreatment reduces breaking points on a progressive ratio schedule reinforced by intravenous cocaine self-administration in the rat, Life Sci., 49 (1991) 833-840.
40. [40] Ritz, M.C., Cone, E.J., Kuhar, M.J., Cocaine inhibition of ligand binding at dopamine, norepinephrine and serotonin transporters - a structure-activity study, Life Sci., 46 (1990) 635-645.
41. [41] Ritz, M.C., Lamb, R.J., Goldberg, S.R. and Kuhar, M.J., Cocaine receptors on dopamine transporters are related to self-administration of cocaine, Science, 237 (1987) 1219-1223.
42. [42] Ricaurte, G. A., Schuster, C.R. and Seiden, L.S., Long-term effects of repeated methylamphetamine administratioin on dopamine and serotonin neurons in the rat brain: a regional study, Brain Res., 193 (1980) 153-163.
43. [43] Robinson, T.E. and Becker, J.B., Enduring changes in brain and behavior produced by chronic amphetamine administration: a review and evaluation of animal models of amphetamine psychosis, Brain Res. Rev., 11 (1986) 157-198.
44. [44] Sarnyai, Z., Vecsernyes, M., Laczi, F., Biro, E. and Szabo, G., Effects of cocaine on the contents of neurohypophyseal hormones in the plasma and in different brain structures in rats, Neuropeptides, 23 (1992) 27-31.
45. [45] Sarnyai, Z., Szabo, G., Kovacs, G.L. and Telegdy, G., Opposite actions of oxytocin and vasopressin in the development of cocaine-induced behavioral sensitization in mice, Pharmacol. Biochem. Behav., 43 (1992) 491-494.
46. [46] Sarnyai, Z., Biro, E., Babarczy, E., Vecsernyes, M., Laczi F., Szabo, G., Krivan, M., Kovacs, G.L. and Telegdy, G., Oxytocin modulates behavioural adaptation to repeated treatment with cocaine in rats, Neuropharmacology, 31 (1992) 593-598.
47. [47] Sawchenko, P.E. and Swanson, L.W., The organization of noradrenergic pathways from the brainstem to the paraventricular and supraoptic nuclei in the rat, Brain Res. Rev., 4 (1982) 275-325.
48. [48] Seiden, L.S. and Kleven, M.S., Lack of toxic effects of cocaine on dopamine or serotonin neurons in the rat brain. In D. Clout et al. (Eds.), Mechanisms of Cocaine Abuse and Toxicity, NIDA Research Monograph 88, US Dept. Health and Human Services, 1988, pp. 276-289.
49. [49] Silverman, A.J., Huffman, D.L. and Zimmerman, E.A., The descending afferent connections of the paraventricular nucleus of the hypothalamus (PVN), Brain Res. Bull., 6 (1981) 47-61.
50. 3H]mazindol-labelling of dopamine transporter in rat nucleus accumbens, Eur. J. Pharmacol, 203 (1991) 141-144.
51. [51] Swanson, L.W. and Sawchenko, P.E., Hypothalamic integration: organization of the paraventricular and supraoptic nuclei, Annu. Rev. Neurosci., 6 (1983) 269-324.
52. [52] Taylor, D. and Ho, B.T., Neurochemical effects of cocaine following acute and repeated injection, J. Neurosci. Res., 3 (1977) 95-101.
53. 3H] Nisoxetine: A radioligand for quantitation of norepinephrine uptake sites by autoradiography or by homogenate binding, J. Pharmacol. Exp. Ther., 260 (1992) 427-436.
54. 3H] Nisoxetine: A new radioligand for norepinephrine uptake sites in brain, Eur. J. Pharmacol., 191 (1990) 239-243.
55. [55] Van Dyke, C., Jatlow, P., Ungerer, J., Barash, P.G. and Byck, R., Oral cocaine: plasma concentrations and central effects, Science, 200 (1978) 211-213.
56. [56] Weddington, W.W., Brown, B.S., Haertzen, C.A., Cone, E.J., Dax, E.M., Herning, R.I. and Michaelson, B.S., Changes in mood, craving, and sleep during short-term abstinence reported by male cocaine addicts, Arch. Gen. Psychiatry, 47 (1990) 861-868.
57. [57] Wiggins, R.C., Rolsten, C., Ruiz, B. and Davis, C.M., Pharmacokinetics of cocaine: basic studies of route, dosage, pregnancy and lactation, Neurotoxicology, 10 (1989) 367-381.
58. 3H-GBR 12,935 are differentially regulated by chronic cocaine self-administration, J. Neurosci., 14 (1994) 2966-1979.
59. [59] Wilson, J.M., Nobrega, J.N., Corrigall, W., Shannak, K., Deck, J.H.N. and Kish, S.J., Influence of chronic cocaine on monoamine neurotransmitters in human brain and animal model: preliminary observations, Ann. NY Acad. Sci., 654 (1992) 461-463.
60. [60] Wilson, J.M., Nobrega, J.N., Corrigall, W., Coen, C.M., Shannak, K. and Kish, S.J., Amygdala dopamine levels are markedly elevated after self-but not passive-administration of cocaine, Brain Res., 668 (1994) 39-45.
61. [61] Wilson, J.M., Levey, A.I., Rajput, A., Ang, L., Guttman, M., Shannak, K., Niznik, H.B., Hornykiewicz, O., Pifl, C. and Kish, S.J., Differential changes in neurochemical markers of striatal dopamine nerve terminals in idiopathic Parkinson's disease, Neurology, (1996) in press.
62. [62] Wise, R.A. and Bozarth, M.A., A psychomotor stimulant theory of addiction, Psychol. Rev., 94 (1987) 469-492.
63. [63] Yeh, S.Y. and DeSouza, E.B., Lack of neurochemical evidence for neurotoxic effects of repeated cocaine administration in rats on brain monoamine neurons, Drug Alcohol Depend., 27 (1991) 51-61.