Synthesis of the farnesyl ether 2,3,5-trifluoro-6-hydroxy-4-[(E,E)-3,7,11-trimethyldodeca-2,6,10-trien-1-yloxy] nitrobenzene, and related compounds containing a substituted hydroxytrifluorophenyl residue: Novel inhibitors of protein farnesyltransferase, geranylgeranyltransferase I and squalene synthase

Journal of the Chemical Society, Perkin Transactions 1

Volumn , Issue 24, 2000, Pages 4265-4278

  Marriott, Jonathan H ^a   Moreno Barber, Amelia M ^a   Hardcastle, Ian R ^a,b   Rowlands, Martin G ^a   Grimshaw, Rachel M ^a   Neidle, Stephen ^a   Jarman, Michael ^a  

^a INSTITUTE OF CANCER RESEARCH   (United Kingdom)

^b NEWCASTLE UNIVERSITY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ALKYLATION; CATALYSIS; ENZYMES; PHASE TRANSITIONS; SYNTHESIS (CHEMICAL);

INHIBITORS;

AROMATIC HYDROCARBONS;

EID: 0034700683     PISSN: 14704358     EISSN: None     Source Type: Journal    
DOI: 10.1039/b007101n     Document Type: Article

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