Stability of cytochrome P450 proteins in cultured precision-cut rat liver slices

Toxicology

Volumn 149, Issue 2-3, 2000, Pages 51-61

  Hashemi, Elham ^a   Till, Clive ^b   Ioannides, Costas ^a  

^a UNIVERSITY OF SURREY   (United Kingdom)

^b Hoechst Roussel Vet   (United Kingdom)

Author keywords

Cytochromes P450; In vitro systems; Krumdieck slicer; Liver slices

Indexed keywords

APOPROTEIN; CYTOCHROME P450; CYTOCHROME P450 ISOENZYME; DEBRISOQUINE 4 HYDROXYLASE; ETHOXYRESORUFIN DEETHYLASE; LAURIC ACID; OXYGENASE; PENTOXYRESORUFIN DEALKYLASE; PROTEIN; TESTOSTERONE; UNSPECIFIC MONOOXYGENASE;

ACCURACY; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DEALKYLATION; ENZYME ACTIVITY; ENZYME STABILITY; LIVER SLICE; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; TECHNIQUE; TESTOSTERONE METABOLISM; TISSUE CULTURE; WESTERN BLOTTING; XENOBIOTIC METABOLISM;

ALKANE 1-MONOOXYGENASE; ANIMALS; ARYL HYDROCARBON HYDROXYLASES; CULTURE TECHNIQUES; CYTOCHROME P-450 CYP1A1; CYTOCHROME P-450 CYP1A2; CYTOCHROME P-450 CYP3A; CYTOCHROME P-450 ENZYME SYSTEM; ENZYME STABILITY; IMMUNOBLOTTING; LIVER; MICROSOMES, LIVER; MIXED FUNCTION OXYGENASES; OXIDOREDUCTASES, N-DEMETHYLATING; RATS; TIME FACTORS;

EID: 0034699048     PISSN: 0300483X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0300-483X(00)00216-X     Document Type: Article

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