Synergism between the calmodulin-binding and autoinhibitory domains on calcineurin is essential for the induction of their phosphatase activity

Journal of Biological Chemistry

Volumn 275, Issue 16, 2000, Pages 11728-11734

  Tokoyoda, Koji ^a   Takemoto, Yoshihiro ^b   Nakayama, Toshinori ^c   Arai, Takao ^a   Kubo, Masato ^a  

^a TOKYO UNIVERSITY OF SCIENCE   (Japan)

^b Development and Medical Affairs Division   (Japan)

^c CHIBA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CALCINEURIN; CALCIUM ION; CALMODULIN; COMPLEMENTARY DNA; MONOCLONAL ANTIBODY; NUCLEAR FACTOR; PHOSPHATASE; T LYMPHOCYTE RECEPTOR;

ARTICLE; CALCIUM CELL LEVEL; DEPHOSPHORYLATION; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME ASSAY; HYBRIDOMA; PLASMID; PRIORITY JOURNAL; T LYMPHOCYTE ACTIVATION;

3T3 CELLS; ANIMALS; BINDING SITES; CALCINEURIN; CALMODULIN; CELL NUCLEUS; DNA-BINDING PROTEINS; MICE; MUTAGENESIS, SITE-DIRECTED; NFATC TRANSCRIPTION FACTORS; NUCLEAR PROTEINS; PHOSPHORIC MONOESTER HYDROLASES; STRUCTURE-ACTIVITY RELATIONSHIP; TRANSCRIPTION FACTORS; TUMOR CELLS, CULTURED;

EID: 0034697320     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.275.16.11728     Document Type: Article

References (45)

1. Rao, A., Luo, C., and Hogan, P. G. (1997) Annu. Rev. Immunol. 15, 707-747
2. Crabtree, G. R., and Clipstone, N. A. (1994) Annu. Rev. Biochem. 63, 1045-1083
3. Liu, J., Farmer, J. D., Jr., Lane, W. S., Friedman, J., Weissman, I., and Schreiber, S. L. (1991) Cell 66, 807-815
4. Clipstone, N. A., and Crabtree, G. R. (1993) Ann. N. Y. Acad. Sci. 696, 20-30
5. Shenolikar, S. (1994) Annu. Rev. Cell Biol. 10, 55-86
6. Klee, C. B., Ren, H., and Wang, X. (1998) J. Biol. Chem. 273, 13367-13370
7. Watanabe, Y., Perrino, B. A., Chang, B. H., and Soderling, T. R. (1995) J. Biol. Chem. 270, 456-460
8. Kincaid, R. L., Giri, P. R., Higuchi, S., Tamura, J., Dixon, S. C., Marietta, C. A., Amorese, D. A., and Martin, B. M. (1990) J. Biol. Chem. 265, 11312-11319
9. Sikkink, R., Haddy, A., MacKelvie, S., Mertz, P., Litwiller, R., and Rusnak, F. (1995) Biochemistry 34, 8348-8356
10. Hashimoto, Y., Perrino, B. A., and Soderling, T. R. (1990) J. Biol. Chem. 265, 1924-1927
11. Parsons, J. N., Wiederrecht, G. J., Salowe, S., Burbaum, J. J., Rokosz, L. L., Kincaid, R. L., and O'Keefe, S. J. (1994) J. Biol. Chem. 269, 19610-19616
12. Clipstone, N. A., and Crabtree, G. R. (1992) Nature 357, 695-697
13. O'Keefe, S. J., Tamura, J., Kincaid, R. L., Tocci, M. J., and O'Neill, E. A. (1992) Nature 357, 692-694
14. Kubo, M., Kincaid, R. L., Webb, D. R., and Ransom, J. T. (1994) Int. Immunol. 6, 179-188
15. Fruman, D. A., Pai, S. Y., Burakoff, S. J., and Bierer, B. E. (1995) Mol. Cell. Biol. 15, 3857-3863
16. McCaffrey, P. G., Luo, C., Kerppola, T. K., Jain, J., Badalian, T. M., Ho, A. M., Burgeon, E., Lane, W. S., Lambert, J. N., Curran, T., Verdine, G. L., Rao, A., and Hogan, P. G. (1993) Science 262, 750-754
17. Northrop, J. P., Ho, S. N., Chen, L., Thomas, D. J., Timmerman, L. A., Nolan, G. P., Admon, A., and Crabtree, G. R. (1994) Nature 369, 497-502
18. Hoey, T., Sun, Y. L., Williamson, K., and Xu, X. (1995) Immunity 2, 461-472
19. Masuda, E. S., Naito, Y., Tokumitsu, H., Campbell, D., Saito, F., Hannum, C., Arai, K., and Arai, N. (1995) Mol. Cell. Biol. 15, 2697-2706
20. Crabtree, G. R. (1999) Cell 96, 611-614
21. Wolfe, S. A., Zhou, P., Dotsch, V., Chen, L., You, A., Ho, S. N., Crabtree, G. R., Wagner, G., and Verdine, G. L. (1997) Nature 385, 172-176
22. Nolan, G. P. (1994) Cell 77, 795-798
23. Timmerman, L. A., Clipstone, N. A., Ho, S. N., Northrop, J. P., and Crabtree, G. R. (1996) Nature 383, 837-840
24. Loh, C., Shaw, K. T., Carew, J., Viola, J. P., Luo, C., Perrino, B. A., and Rao, A. (1996) J. Biol. Chem. 271, 10884-10891
25. Luo, C., Shaw, K. T., Raghavan, A., Aramburu, J., Garcia-Cozar, F., Perrino, B. A., Hogan, P. G., and Rao, A. (1996) Proc. Natl. Acad. Sci. U. S. A. 93, 8907-8912
26. Masuda, E. S., Liu, J., Imamura, R., Imai, S. I., Arai, K. I., and Arai, N. (1997) Mol. Cell. Biol. 17, 2066-2075
27. Zhu, J., Shibasaki, F., Price, R., Guillemot, J. C., Yano, T., Dotsch, V., Wagner, G., Ferrara, P., and McKeon, F. (1998) Cell 93, 851-861
28. Shibasaki, F., Price, E. R., Milan, D., and McKeon, F. (1996) Nature 382, 370-373
29. Jayaraman, T., Brillantes, A. M., Timerman, A. P., Fleischer, S., Erdjument-Bromage, H., Tempst, P., and Marks, A. R. (1992) J. Biol. Chem. 267, 9474-9477
30. Cameron, A. M., Steiner, J. P., Roskams, A. J., Ali, S. M., Ronnett, G. V., and Snyder, S. H. (1995) Cell 83, 463-472
31. Cameron, A. M., Nucifora, F. C., Jr., Fung, E. T., Livingston, D. J., Aldape, R. A., Ross, C. A., and Snyder, S. H. (1997) J. Biol. Chem. 272, 27582-27588
32. Brillantes, A. B., Ondrias, K., Scott, A., Kobrinsky, E., Ondriasova, E., Moschella, M. C., Jayaraman, T., Landers, M., Ehrlich, B. E., and Marks, A. R. (1994) Cell 77, 513-523
33. Coghlan, V. M., Perrino, B. A., Howard, M., Langeberg, L. K., Hicks, J. B., Gallatin, W. M., and Scott, J. D. (1995) Science 267, 108-111
34. Sun, L., Youn, H. D., Loh, C., Stolow, M., He, W., and Liu, J. O. (1998) Immunity 8, 703-711
35. Lai, M. M., Burnett, P. E., Wolosker, H., Blackshaw, S., and Snyder, S. H. (1998) J. Biol. Chem. 273, 18325-18331
36. Winder, D. G., Mansuy, I. M., Osman, M., Moallem, T. M., and Kandel, E. R. (1998) 92, 25-37
37. Jain, J., McCaffrey, P. G., Miner, Z., Kerppola, T. K., Lambert, J. N., Verdine, G. L., Curran, T., and Rao, A. (1993) Nature 365, 352-355
38. Griffith, J. P., Kim, J. L., Kim, E. E., Sintchak, M. D., Thomson, J. A., Fitzgibbon, M. J., Fleming, M. A., Caron, P. R., Hsiao, K., and Navia, M. A. (1995) Cell 82, 507-522
39. Kissinger, C. R., Parge, H. E., Knighton, D. R., Lewis, C. T., Pelletier, L. A., Tempczyk, A., Kalish, V. J., Tucker, K. D., Showalter, R. E., Moomaw, E. W., Gastinel, L. N., Habuka, N., Chen, X., Maldonado, F., Barker, J. E., Bacquet, R., and Villafranca, J. E. (1995) Nature 378, 641-644
40. Aramburu, J., Garcia-Cozar, F., Raghavan, A., Okamura, H., Rao, A., and Hogan, P. G. (1998) Mol. Cell. 1, 627-637
41. Garcia-Cozar, F. J., Okamura, H., Aramburu, J. F., Shaw, K. T. Y., Pelletier, L., Showalter, R., Villafranca, E., and Rao, A. (1998) J. Biol. Chem. 273, 23877-23883
42. Giri, P. R., Higuchi, S., and Kincaid, R. L. (1991) Biochem. Biophys. Res. Commun. 181, 252-258
43. Muramatsu, T., Giri, P. R., Higuchi, S., and Kincaid, R. L. (1992) Proc. Natl. Acad. Sci. U. S. A. 89, 529-533
44. Kashishian, A., Howard, M., Loh, C., Gallatin, W. M., Hoekstra, M. F., and Lai, Y. (1998) J. Biol. Chem. 273, 27412-2749
45. Zhu, J., and McKeon, F. (1999) Nature 398, 256-260