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Volumn 18, Issue 1, 1996, Pages 1-24

Experimental immunotherapies for multiple sclerosis

Author keywords

[No Author keywords available]

Indexed keywords

15 DEOXYSPERGUALIN; ANTIINFLAMMATORY AGENT; AZATHIOPRINE; BETA INTERFERON; CD4 ANTIGEN; CLADRIBINE; CYCLOPHOSPHAMIDE; CYCLOSPORIN; GAMMA INTERFERON; INTERCELLULAR ADHESION MOLECULE 1; INTERCELLULAR ADHESION MOLECULE 1 ANTIBODY; LYMPHOTOXIN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; METHOTREXATE; MITOXANTRONE; MYELIN BASIC PROTEIN; PROTEOLIPID PROTEIN; T LYMPHOCYTE RECEPTOR; TUMOR NECROSIS FACTOR ALPHA;

EID: 0030014629     PISSN: 03444325     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF00792605     Document Type: Review
Times cited : (19)

References (163)
  • 2
    • 0028293458 scopus 로고
    • Intravenous immunoglobulin treatment of experimental T cell-mediated autoimmune disease. Upregulation of T cell proliferation and downregulation of tumor necrosis factor α secretion
    • Achiron A, Margalit R, Hershkoviz R, Markovits D, Reshef T, Melamed E, Cohen IR, Lider O (1944) Intravenous immunoglobulin treatment of experimental T cell-mediated autoimmune disease. Upregulation of T cell proliferation and downregulation of tumor necrosis factor α secretion. J Clin Invest 93:600
    • (1944) J Clin Invest , vol.93 , pp. 600
    • Achiron, A.1    Margalit, R.2    Hershkoviz, R.3    Markovits, D.4    Reshef, T.5    Melamed, E.6    Cohen, I.R.7    Lider, O.8
  • 3
    • 0025780265 scopus 로고
    • Immunomodulation of experimental allergic encephalomyelitis by antibodies to the antigen-Ia complex
    • Aharoni R, Teitelbaum D, Arnon R, Puri J (1991) Immunomodulation of experimental allergic encephalomyelitis by antibodies to the antigen-Ia complex. Nature 351:147
    • (1991) Nature , vol.351 , pp. 147
    • Aharoni, R.1    Teitelbaum, D.2    Arnon, R.3    Puri, J.4
  • 4
    • 0028146261 scopus 로고
    • Antigen-driven tissue-specific suppression following oral tolerance: Orally admistered myelin basic protein suppresses proteolipid protein-induced experimental autoimmune encephalomyelitis in the SJL mouse
    • Al-Sabbagh A, Miller A, Santos LMB, Weiner HL (1994) Antigen-driven tissue-specific suppression following oral tolerance: orally admistered myelin basic protein suppresses proteolipid protein-induced experimental autoimmune encephalomyelitis in the SJL mouse. Eur J Immunol 24:2104
    • (1994) Eur J Immunol , vol.24 , pp. 2104
    • Al-Sabbagh, A.1    Miller, A.2    Santos, L.M.B.3    Weiner, H.L.4
  • 5
    • 0028006884 scopus 로고
    • Identification of epitopes of myelin oligodendrocyte glycoprotein for the induction of experimental allergic encephalomyelitis in SJL and Biozzi AB/H mice
    • Amor S, Groome N, Linington C, Morris MM, Dornmair K, Gardinier MV, Matthieu J-M, Baker D (1994) Identification of epitopes of myelin oligodendrocyte glycoprotein for the induction of experimental allergic encephalomyelitis in SJL and Biozzi AB/H mice. J Immunol 153:4349
    • (1994) J Immunol , vol.153 , pp. 4349
    • Amor, S.1    Groome, N.2    Linington, C.3    Morris, M.M.4    Dornmair, K.5    Gardinier, M.V.6    Matthieu, J.-M.7    Baker, D.8
  • 6
    • 0024368359 scopus 로고
    • Encephalitogenic T cells in the B10.PL model of experimental allergic encephalomyelitis (EAE) are of the Th-1 lymphokine subtype
    • Ando DG, Clayton J, Kono D, Urban JL, Sercarz EE (1989) Encephalitogenic T cells in the B10.PL model of experimental allergic encephalomyelitis (EAE) are of the Th-1 lymphokine subtype. Cell Immunol 124:132
    • (1989) Cell Immunol , vol.124 , pp. 132
    • Ando, D.G.1    Clayton, J.2    Kono, D.3    Urban, J.L.4    Sercarz, E.E.5
  • 8
    • 0028066844 scopus 로고
    • Control of established experimental allergic encephalomyelitis by inhibition of tumor necrosis factor (TNF) activity within the central nervous system using monoclonal antibodies and TNF receptor-immunoglobulin fusion proteins
    • Baker D, Butler D, Scallon BJ, O'Neill JK, Turk JL, Feldmann M (1994) Control of established experimental allergic encephalomyelitis by inhibition of tumor necrosis factor (TNF) activity within the central nervous system using monoclonal antibodies and TNF receptor-immunoglobulin fusion proteins. Eur J Immunol 24:2040
    • (1994) Eur J Immunol , vol.24 , pp. 2040
    • Baker, D.1    Butler, D.2    Scallon, B.J.3    O'Neill, J.K.4    Turk, J.L.5    Feldmann, M.6
  • 9
    • 0027529932 scopus 로고
    • Surface expression of α4 integrin by CD4 T cells is required for their entry into brain parenchyma
    • Baron JL, Madri JA, Ruddle NH, Hashim G, Janeway CA (1993) Surface expression of α4 integrin by CD4 T cells is required for their entry into brain parenchyma. J Exp Med 177:57
    • (1993) J Exp Med , vol.177 , pp. 57
    • Baron, J.L.1    Madri, J.A.2    Ruddle, N.H.3    Hashim, G.4    Janeway, C.A.5
  • 10
    • 0027318299 scopus 로고
    • Diverse T cell receptor Vβ gene usage in the central nervous system in experimental allergic encephalomyelitis
    • Bell RB, Lindsey JW, Sobel RA, Hodgkinson S, Steinman L (1993) Diverse T cell receptor Vβ gene usage in the central nervous system in experimental allergic encephalomyelitis. J Immunol 150:4085
    • (1993) J Immunol , vol.150 , pp. 4085
    • Bell, R.B.1    Lindsey, J.W.2    Sobel, R.A.3    Hodgkinson, S.4    Steinman, L.5
  • 11
    • 0019487117 scopus 로고
    • Vaccination against autoimmune encephalomyelitis with T-lymphocyte line cells reactive against myelin basic protein
    • Ben Nun A, Wekerle H, Cohen IR (1981) Vaccination against autoimmune encephalomyelitis with T-lymphocyte line cells reactive against myelin basic protein. Nature 293:60
    • (1981) Nature , vol.293 , pp. 60
    • Ben Nun, A.1    Wekerle, H.2    Cohen, I.R.3
  • 12
    • 0023927111 scopus 로고
    • Suppression of experimental autoimmune encephalomyelitis by the oral administration of myelin basic protein
    • Bitar DM, Whitacre CC (1988) Suppression of experimental autoimmune encephalomyelitis by the oral administration of myelin basic protein. Cell Immunol 112:364
    • (1988) Cell Immunol , vol.112 , pp. 364
    • Bitar, D.M.1    Whitacre, C.C.2
  • 13
    • 0026642495 scopus 로고
    • Stimulation or tolerization of an anti-myelin basic protein T lymphocyte line with membrane fragments from antigen presenting cells
    • Boggs JM, Chang NH, Goundalkar A, Hashim GA (1992) Stimulation or tolerization of an anti-myelin basic protein T lymphocyte line with membrane fragments from antigen presenting cells. Cell Immunol 143:23
    • (1992) Cell Immunol , vol.143 , pp. 23
    • Boggs, J.M.1    Chang, N.H.2    Goundalkar, A.3    Hashim, G.A.4
  • 15
    • 0027454052 scopus 로고
    • Induction of relapsing paralysis in experimental allergic encephalomyelitis by bacterial superantigen
    • Brocke S, Gaur, A, Piercy C, Gautam A, Gijbels K, Fathman CG, Steinman L. (1993) Induction of relapsing paralysis in experimental allergic encephalomyelitis by bacterial superantigen. Nature 365:642
    • (1993) Nature , vol.365 , pp. 642
    • Brocke, S.1    Gaur, A.2    Piercy, C.3    Gautam, A.4    Gijbels, K.5    Fathman, C.G.6    Steinman, L.7
  • 16
    • 0025313253 scopus 로고
    • Lymphotoxin and tumor necrosis factor-alpha production by myelin basic protein-specific T cell clones correlates with encephalitogenicity
    • Broome Powell M, Mitchell D, Lederman J, Buckmeier J, Zamvil SS, Graham M, Ruddle N, Steinman L (1990) Lymphotoxin and tumor necrosis factor-alpha production by myelin basic protein-specific T cell clones correlates with encephalitogenicity. Int Immunol 2:539
    • (1990) Int Immunol , vol.2 , pp. 539
    • Broome Powell, M.1    Mitchell, D.2    Lederman, J.3    Buckmeier, J.4    Zamvil, S.S.5    Graham, M.6    Ruddle, N.7    Steinman, L.8
  • 17
    • 0021186832 scopus 로고
    • Experimental allergic encephalomyelitis: Successful treatment in vivo with a monoclonal antibody that recognizes T helper cells
    • Brostoff SW, Mason DW (1984) Experimental allergic encephalomyelitis: Successful treatment in vivo with a monoclonal antibody that recognizes T helper cells. J Immunol 133:1938
    • (1984) J Immunol , vol.133 , pp. 1938
    • Brostoff, S.W.1    Mason, D.W.2
  • 18
    • 0028174301 scopus 로고
    • Analysis of Vβ8-CDR3 sequences derived from central nervous system of Lewis rats with experimental autoimmune encephalomyelitis
    • Buenafe AC, Vainiene M, Celnik B, Vandenbark AA, Offner H (1994) Analysis of Vβ8-CDR3 sequences derived from central nervous system of Lewis rats with experimental autoimmune encephalomyelitis. J Immunol 153:386
    • (1994) J Immunol , vol.153 , pp. 386
    • Buenafe, A.C.1    Vainiene, M.2    Celnik, B.3    Vandenbark, A.A.4    Offner, H.5
  • 19
    • 0024530958 scopus 로고
    • Both rat and mouse T cell receptors specific for the encephalitogenic determinant of myelin basic protein use similar Vα and Vβ chain genes even though the major histocompatibility complex and encephalitogenic determinants being recognized are different
    • Burns FR, Li X, Shen N, Offner H, Chou YK, A. V, Heber-Katz A (1989) Both rat and mouse T cell receptors specific for the encephalitogenic determinant of myelin basic protein use similar Vα and Vβ chain genes even though the major histocompatibility complex and encephalitogenic determinants being recognized are different. J Exp Med 169:27
    • (1989) J Exp Med , vol.169 , pp. 27
    • Burns, F.R.1    Li, X.2    Shen, N.3    Offner, H.4    Chou, Y.K.5    V, A.6    Heber-Katz, A.7
  • 20
    • 0020551984 scopus 로고
    • Isolation of myelin basic protein-reactive T-cell lines from normal human blood
    • Burns J, Rosenzweig A, Zweiman B, Lisak RP (1983) Isolation of myelin basic protein-reactive T-cell lines from normal human blood. Cell Immunol 81:435
    • (1983) Cell Immunol , vol.81 , pp. 435
    • Burns, J.1    Rosenzweig, A.2    Zweiman, B.3    Lisak, R.P.4
  • 21
    • 0024999613 scopus 로고
    • Upregulation and coexpression of adhesion molecules correlate with relapsing autoimmune demyelination in the central nervous system
    • Cannella B, Cross AH, Raine CS (1990) Upregulation and coexpression of adhesion molecules correlate with relapsing autoimmune demyelination in the central nervous system. J Exp Med 172:1521
    • (1990) J Exp Med , vol.172 , pp. 1521
    • Cannella, B.1    Cross, A.H.2    Raine, C.S.3
  • 22
    • 0027448726 scopus 로고
    • Anti-adhesion molecule therapy in experimental autoimmune encephalomyelitis
    • Cannella B, Cross AH, Raine CS (1993) Anti-adhesion molecule therapy in experimental autoimmune encephalomyelitis. J Neuroimmunol 46:43
    • (1993) J Neuroimmunol , vol.46 , pp. 43
    • Cannella, B.1    Cross, A.H.2    Raine, C.S.3
  • 23
    • 0028089802 scopus 로고
    • Macrophage inactivation IL-13 suppresses experimental autoimmune encephalomyelitis in rats
    • Cash E, Minty A, Ferrara P, Caput D, Fradelizi D, Rott O (1994) Macrophage inactivation IL-13 suppresses experimental autoimmune encephalomyelitis in rats. J Immunol 153:4258
    • (1994) J Immunol , vol.153 , pp. 4258
    • Cash, E.1    Minty, A.2    Ferrara, P.3    Caput, D.4    Fradelizi, D.5    Rott, O.6
  • 24
    • 0028037782 scopus 로고
    • Regulatory T cell clones induced by oral tolerance: Suppression of autoimmune encephalomyelitis
    • Chen Y, Kuchroo VK, Inobe J-I, Hafler DA, Weiner HL (1994) Regulatory T cell clones induced by oral tolerance: suppression of autoimmune encephalomyelitis. Science 265:1237
    • (1994) Science , vol.265 , pp. 1237
    • Chen, Y.1    Kuchroo, V.K.2    Inobe, J.-I.3    Hafler, D.A.4    Weiner, H.L.5
  • 25
    • 0024603242 scopus 로고
    • T cell receptor β chain usage in myelin basic protein-specific rat T lymphocytes
    • Chluba J, Steeg C, Becker A, Wekerle H, Epplen JT (1989) T cell receptor β chain usage in myelin basic protein-specific rat T lymphocytes. Eur J Immunol 19:279
    • (1989) Eur J Immunol , vol.19 , pp. 279
    • Chluba, J.1    Steeg, C.2    Becker, A.3    Wekerle, H.4    Epplen, J.T.5
  • 26
    • 0026948591 scopus 로고
    • Tumor necrosis factor alpha production as a possible predictor of relapse in patients with multiple sclerosis
    • Chofflon M, Juillard C, Juillard P, Gauthier G, Grau GE (1992) Tumor necrosis factor alpha production as a possible predictor of relapse in patients with multiple sclerosis. Eur Cytokine Netw 3:523
    • (1992) Eur Cytokine Netw , vol.3 , pp. 523
    • Chofflon, M.1    Juillard, C.2    Juillard, P.3    Gauthier, G.4    Grau, G.E.5
  • 28
    • 0024592929 scopus 로고
    • Peptide-specific prevention of experimental allergic encephalomyelitis. Neonatal tolerance induced to the dominant T cell determinant of myelin basic protein
    • Clayton JP, Gammon GM, Ando DG, Kono DH, Hood L, Sercarz EE (1989) Peptide-specific prevention of experimental allergic encephalomyelitis. Neonatal tolerance induced to the dominant T cell determinant of myelin basic protein. J Exp Med 169:1681
    • (1989) J Exp Med , vol.169 , pp. 1681
    • Clayton, J.P.1    Gammon, G.M.2    Ando, D.G.3    Kono, D.H.4    Hood, L.5    Sercarz, E.E.6
  • 30
    • 0025127157 scopus 로고
    • Homing to central nervous system vasculature by antigen specific lymphocytes. I. Localization of 14C-labeled cells during acute, chronic and relapsing experimental allergic encephalomyelitis
    • Cross AH, Cannella B, Brosnan CF, Raine CS (1990) Homing to central nervous system vasculature by antigen specific lymphocytes. I. Localization of 14C-labeled cells during acute, chronic and relapsing experimental allergic encephalomyelitis. Lab Invest 63:162
    • (1990) Lab Invest , vol.63 , pp. 162
    • Cross, A.H.1    Cannella, B.2    Brosnan, C.F.3    Raine, C.S.4
  • 31
    • 0027174925 scopus 로고
    • Chronologic localization of myelin-reactive cells in the lesions of relapsing EAE: Implications for the study of multiple sclerosis
    • Cross AH, O'Mara T, Raine CS (1993) Chronologic localization of myelin-reactive cells in the lesions of relapsing EAE: implications for the study of multiple sclerosis. Neurology 43:1028
    • (1993) Neurology , vol.43 , pp. 1028
    • Cross, A.H.1    O'Mara, T.2    Raine, C.S.3
  • 32
    • 0028360840 scopus 로고
    • Aminoguanidine, an inhibitor of inducible nitric oxide synthase, ameliorates experimental autoimmune encephalomyelitis in SJL mice
    • Cross AH, Misko TP, Lin RF, Hickey WF, Trotter JL, Tilton RG (1994) Aminoguanidine, an inhibitor of inducible nitric oxide synthase, ameliorates experimental autoimmune encephalomyelitis in SJL mice. J Clin Invest 93:2684
    • (1994) J Clin Invest , vol.93 , pp. 2684
    • Cross, A.H.1    Misko, T.P.2    Lin, R.F.3    Hickey, W.F.4    Trotter, J.L.5    Tilton, R.G.6
  • 34
    • 0028019230 scopus 로고
    • Expression of ICAM-1, VCAM-1, L-selectin, and leukosialin in the mouse central nervous system during the induction and remission of experimental allergic encephalomyelitis
    • Dopp JM, Breneman SM, Olschowska JA (1994) Expression of ICAM-1, VCAM-1, L-selectin, and leukosialin in the mouse central nervous system during the induction and remission of experimental allergic encephalomyelitis. J Neuroimmunol 54:129
    • (1994) J Neuroimmunol , vol.54 , pp. 129
    • Dopp, J.M.1    Breneman, S.M.2    Olschowska, J.A.3
  • 35
    • 0027333348 scopus 로고
    • Tickling the TCR: Selective T cell functions stimulated by altered peptide ligands
    • Evavold BD, Sloan-Lancaster J, Allen PM (1993) Tickling the TCR: selective T cell functions stimulated by altered peptide ligands. Immunol Today 14:602
    • (1993) Immunol Today , vol.14 , pp. 602
    • Evavold, B.D.1    Sloan-Lancaster, J.2    Allen, P.M.3
  • 36
    • 0024840204 scopus 로고
    • Encephalitogenic epitopes of myelin basic protein
    • Fritz RB, McFarlin DE (1989) Encephalitogenic epitopes of myelin basic protein. Chem Immunol 46:101
    • (1989) Chem Immunol , vol.46 , pp. 101
    • Fritz, R.B.1    McFarlin, D.E.2
  • 37
    • 0021924965 scopus 로고
    • Major histocompatibility complex-linked control of the murine immune response to myelin basic protein
    • Fritz RB, Skeen MJ, Jen-Chou CH, Garcia M, Egorov IK (1985) Major histocompatibility complex-linked control of the murine immune response to myelin basic protein. J Immunol 134:2328
    • (1985) J Immunol , vol.134 , pp. 2328
    • Fritz, R.B.1    Skeen, M.J.2    Jen-Chou, C.H.3    Garcia, M.4    Egorov, I.K.5
  • 38
    • 0027056539 scopus 로고
    • Amelioration of autoimmune encephalomyelitis by myelin basic protein synthetic peptide-induced anergy
    • Gaur A, Wiers B, Liu A, Rothbard J, Fathman CG (1992) Amelioration of autoimmune encephalomyelitis by myelin basic protein synthetic peptide-induced anergy. Science 258:1491
    • (1992) Science , vol.258 , pp. 1491
    • Gaur, A.1    Wiers, B.2    Liu, A.3    Rothbard, J.4    Fathman, C.G.5
  • 41
    • 9344264160 scopus 로고
    • Prevention of EAE in non-human primates by a type IV phosphodiesterase inhibitor that suppresses tumor necrosis factor
    • Genain CP, Nguyen MH, Faulds D, Uccelli A, Davis RL, Hedgpeth J, Hauser SL (1994) Prevention of EAE in non-human primates by a type IV phosphodiesterase inhibitor that suppresses tumor necrosis factor. J Neuroimmunol 54:163
    • (1994) J Neuroimmunol , vol.54 , pp. 163
    • Genain, C.P.1    Nguyen, M.H.2    Faulds, D.3    Uccelli, A.4    Davis, R.L.5    Hedgpeth, J.6    Hauser, S.L.7
  • 42
    • 0026577829 scopus 로고
    • Diversity of T cell receptor alpha and beta chain genes expressed by human T cells specific for similar myelin basic protein peptide/major histocompatibility complexes
    • Giegerich G, Pette M, Meinl E, Epplen JT, Wekerle H, Hinkkanen A (1992) Diversity of T cell receptor alpha and beta chain genes expressed by human T cells specific for similar myelin basic protein peptide/major histocompatibility complexes. Eur J Immunol 22:753
    • (1992) Eur J Immunol , vol.22 , pp. 753
    • Giegerich, G.1    Pette, M.2    Meinl, E.3    Epplen, J.T.4    Wekerle, H.5    Hinkkanen, A.6
  • 43
    • 0027944171 scopus 로고
    • Reversal of experimental autoimmune encephalomyelitis with a hydroxamate inhibitor of matrix metalloproteases
    • Gijbels K, Galardy RE, Steinman L (1994) Reversal of experimental autoimmune encephalomyelitis with a hydroxamate inhibitor of matrix metalloproteases. J Clin Invest 94:2177
    • (1994) J Clin Invest , vol.94 , pp. 2177
    • Gijbels, K.1    Galardy, R.E.2    Steinman, L.3
  • 44
    • 0028089783 scopus 로고
    • Immunological tolerance to a defined myelin basic protein antigen administered intrathymically
    • Goss JA, Nakafusa Y, Roland CR, Hickey WF, Flye M (1994) Immunological tolerance to a defined myelin basic protein antigen administered intrathymically. J Immunol 153:3890
    • (1994) J Immunol , vol.153 , pp. 3890
    • Goss, J.A.1    Nakafusa, Y.2    Roland, C.R.3    Hickey, W.F.4    Flye, M.5
  • 45
    • 0027384272 scopus 로고
    • Oral tolerance in experimental autoimmune uveoretinitis. Distinct mechanisms of resistance are induced by low dose vs high dose feeding protocols
    • Gregerson DS, Obritsch WF, Donoso LA (1993) Oral tolerance in experimental autoimmune uveoretinitis. Distinct mechanisms of resistance are induced by low dose vs high dose feeding protocols. J Immunol 151:5751
    • (1993) J Immunol , vol.151 , pp. 5751
    • Gregerson, D.S.1    Obritsch, W.F.2    Donoso, L.A.3
  • 46
    • 0025854083 scopus 로고
    • Serial gadolinium-enhanced magnetic resonance imaging scans in patients with early, relapsing-remitting multiple sclerosis: Implication for clinical trials and natural history
    • Harris JO, Frank JO, Patronas N, McFarlin DE, McFarland HF (1991) Serial gadolinium-enhanced magnetic resonance imaging scans in patients with early, relapsing-remitting multiple sclerosis: Implication for clinical trials and natural history. Ann Neurol 29:548
    • (1991) Ann Neurol , vol.29 , pp. 548
    • Harris, J.O.1    Frank, J.O.2    Patronas, N.3    McFarlin, D.E.4    McFarland, H.F.5
  • 47
    • 0025981021 scopus 로고
    • T-lymphocyte entry into the central nervous system
    • Hickey WF, Hsu BL, Kimura H (1991) T-lymphocyte entry into the central nervous system. J Neurosci. Res 28:254
    • (1991) J Neurosci. Res , vol.28 , pp. 254
    • Hickey, W.F.1    Hsu, B.L.2    Kimura, H.3
  • 48
    • 0024468234 scopus 로고
    • Vaccination against experimental allergic autoimmune encephalomyelitis with T cell receptor peptides
    • Howell MD, Winters ST, Olee T, Powell HC, Carlo DJ, Brostoff SW (1989) Vaccination against experimental allergic autoimmune encephalomyelitis with T cell receptor peptides. Science 246:668
    • (1989) Science , vol.246 , pp. 668
    • Howell, M.D.1    Winters, S.T.2    Olee, T.3    Powell, H.C.4    Carlo, D.J.5    Brostoff, S.W.6
  • 50
    • 0025856061 scopus 로고
    • Experimental autoimmune encephalomyelitis is exacerbated by IL-1α and suppressed by soluble IL-1 receptors
    • Jacobs CA, Baker PE, Roux ER, Picha KS, Toivola B, Waugh S, Kennedy MK (1991) Experimental autoimmune encephalomyelitis is exacerbated by IL-1α and suppressed by soluble IL-1 receptors. J Immunol 146:2983
    • (1991) J Immunol , vol.146 , pp. 2983
    • Jacobs, C.A.1    Baker, P.E.2    Roux, E.R.3    Picha, K.S.4    Toivola, B.5    Waugh, S.6    Kennedy, M.K.7
  • 51
    • 0028298846 scopus 로고
    • A rationally designed CD4 analogue inhibits experimental allergic encephalomyelitis
    • Jameson BA, McDonnell JM, Marini JC, Korngold R (1994) A rationally designed CD4 analogue inhibits experimental allergic encephalomyelitis. Nature 368:744
    • (1994) Nature , vol.368 , pp. 744
    • Jameson, B.A.1    McDonnell, J.M.2    Marini, J.C.3    Korngold, R.4
  • 52
    • 0026006736 scopus 로고
    • Successful treatment of experimental allergic encephalomyelitis with transforming growth factor-β1
    • Johns LD, Flanders KC, Ranges GE, Sriram S (1991) Successful treatment of experimental allergic encephalomyelitis with transforming growth factor-β1. J Immunol 147:1792
    • (1991) J Immunol , vol.147 , pp. 1792
    • Johns, L.D.1    Flanders, K.C.2    Ranges, G.E.3    Sriram, S.4
  • 53
    • 0026502380 scopus 로고
    • Mapping T-cell receptor-peptide contacts by variant peptide immunization of single-chain transgenics
    • Jorgensen JL, Esser U, Fazekas de St. Groth B, Reay PA, Davis MM (1992) Mapping T-cell receptor-peptide contacts by variant peptide immunization of single-chain transgenics. Nature 355:224
    • (1992) Nature , vol.355 , pp. 224
    • Jorgensen, J.L.1    Esser, U.2    Fazekas De St. Groth, B.3    Reay, P.A.4    Davis, M.M.5
  • 54
    • 0027196705 scopus 로고
    • Selective and nonselective stages in homing of T lymphocytes to central nervous system during experimental allergic encephalomyelitis
    • Karin N, Szafer F, Mitchell D, Gold DP, Steinman L (1993) Selective and nonselective stages in homing of T lymphocytes to central nervous system during experimental allergic encephalomyelitis. J Immunol 150:4116
    • (1993) J Immunol , vol.150 , pp. 4116
    • Karin, N.1    Szafer, F.2    Mitchell, D.3    Gold, D.P.4    Steinman, L.5
  • 55
    • 0028148199 scopus 로고
    • Reversal of experimental autoimmune encephalomyelitis by a soluble peptide variant of a myelin basic protein epitope: T cell receptor antagonism and reduction of interferon γ and tumor necrosis factor α production
    • Karin N, Mitchell DJ, Brocke S, Ling N, Steinman L (1994) Reversal of experimental autoimmune encephalomyelitis by a soluble peptide variant of a myelin basic protein epitope: T cell receptor antagonism and reduction of interferon γ and tumor necrosis factor α production. J Exp Med 180:2227
    • (1994) J Exp Med , vol.180 , pp. 2227
    • Karin, N.1    Mitchell, D.J.2    Brocke, S.3    Ling, N.4    Steinman, L.5
  • 56
    • 0025914918 scopus 로고
    • Trials of vaccination against experimental autoimmune uveoretinitis with a T-cell receptor peptide
    • Kawano Y-I, Sasamoto Y, Kotake S, Thurau SR, Wiggert B, Gery I (1991) Trials of vaccination against experimental autoimmune uveoretinitis with a T-cell receptor peptide. Curr Eye Res 10:789
    • (1991) Curr Eye Res , vol.10 , pp. 789
    • Kawano, Y.-I.1    Sasamoto, Y.2    Kotake, S.3    Thurau, S.R.4    Wiggert, B.5    Gery, I.6
  • 57
    • 0025174370 scopus 로고
    • Inhibition of murine relapsing experimental autoimmune encephalomyelitis by immune tolerance to proteolipid protein and its encephalitogenic peptides
    • Kennedy MK, L.-J T, Dal Canto MC, Tuohy VK, Lu Z, Trotter JL, Miller SD (1990) Inhibition of murine relapsing experimental autoimmune encephalomyelitis by immune tolerance to proteolipid protein and its encephalitogenic peptides. J Immunol 144:909
    • (1990) J Immunol , vol.144 , pp. 909
    • Kennedy, M.K.1    T, L.-J.2    Dal Canto, M.C.3    Tuohy, V.K.4    Lu, Z.5    Trotter, J.L.6    Miller, S.D.7
  • 58
    • 0025310390 scopus 로고
    • Regulation of the effector stages of experimental autoimmune encephalomyelitis via neuroantigen-specific tolerance induction
    • Kennedy MK, Tan L-J, Dal Canto MC, Miller SD (1990) Regulation of the effector stages of experimental autoimmune encephalomyelitis via neuroantigen-specific tolerance induction. J Immunol 145:117
    • (1990) J Immunol , vol.145 , pp. 117
    • Kennedy, M.K.1    Tan, L.-J.2    Dal Canto, M.C.3    Miller, S.D.4
  • 59
    • 0026707402 scopus 로고
    • Analysis of cytokine mRNA expression in the central nervous system of mice with experimental autoimmune encephalomyelitis reveals that IL-10 mRNA expression correlates with recovery
    • Kennedey MK, Torrance DS, Picha KS, Mohler KM (1992) Analysis of cytokine mRNA expression in the central nervous system of mice with experimental autoimmune encephalomyelitis reveals that IL-10 mRNA expression correlates with recovery. J Immunol 149:2496
    • (1992) J Immunol , vol.149 , pp. 2496
    • Kennedey, M.K.1    Torrance, D.S.2    Picha, K.S.3    Mohler, K.M.4
  • 60
    • 0027990803 scopus 로고
    • Experimental autoimmune panencephalitis and uveoretinitis transferred to the Lewis rat by T lymphocytes specific for the S100β molecule, a calcium binding protein of astroglia
    • Kojima K, Berger T, Lassmann H, Hinze-Selch D, Zhang Y, Gehrmann J, Reske K, Wekerle H, Linington C (1994) Experimental autoimmune panencephalitis and uveoretinitis transferred to the Lewis rat by T lymphocytes specific for the S100β molecule, a calcium binding protein of astroglia. J Exp Med 180:817
    • (1994) J Exp Med , vol.180 , pp. 817
    • Kojima, K.1    Berger, T.2    Lassmann, H.3    Hinze-Selch, D.4    Zhang, Y.5    Gehrmann, J.6    Reske, K.7    Wekerle, H.8    Linington, C.9
  • 62
    • 0027427223 scopus 로고
    • Cytokines and adhesion molecules contribute to the ability of myelin proteolipid protein-specific T cell clones to mediate experimental allergic encephalomyelitis
    • Kuchroo VK, Martin CA, Greer JM, Ju S-T, Sobel RA, Dorf ME (1993) Cytokines and adhesion molecules contribute to the ability of myelin proteolipid protein-specific T cell clones to mediate experimental allergic encephalomyelitis. J Immunol 151:4371
    • (1993) J Immunol , vol.151 , pp. 4371
    • Kuchroo, V.K.1    Martin, C.A.2    Greer, J.M.3    Ju, S.-T.4    Sobel, R.A.5    Dorf, M.E.6
  • 63
    • 0027964523 scopus 로고
    • A single TCR antagonist peptide inhibits experimental allergic encephalomyelitis mediated by a diverse T cell repertoire
    • Kuchroo VK, Greer JM, Kaul D, Ishioka G, Franco A, Sette A, Sobel RA, Lees MB (1994) A single TCR antagonist peptide inhibits experimental allergic encephalomyelitis mediated by a diverse T cell repertoire. J Immunol 153:3326
    • (1994) J Immunol , vol.153 , pp. 3326
    • Kuchroo, V.K.1    Greer, J.M.2    Kaul, D.3    Ishioka, G.4    Franco, A.5    Sette, A.6    Sobel, R.A.7    Lees, M.B.8
  • 64
    • 0028295323 scopus 로고
    • Vaccination with T cell receptor peptides primes anti-receptor cytotoxic T lymphocytes (CTL) and anergizes T cells specifically recognized by these CTL
    • Kuhröber A, Schirmbeck R, Reimann J (1994) Vaccination with T cell receptor peptides primes anti-receptor cytotoxic T lymphocytes (CTL) and anergizes T cells specifically recognized by these CTL. Eur J Immunol 24:1172
    • (1994) Eur J Immunol , vol.24 , pp. 1172
    • Kuhröber, A.1    Schirmbeck, R.2    Reimann, J.3
  • 65
    • 0027249369 scopus 로고
    • + T cells in recovery from antigen-induced autoimmune disease
    • + T cells in recovery from antigen-induced autoimmune disease. J Exp Med 178:909
    • (1993) J Exp Med , vol.178 , pp. 909
    • Kumar, V.1    Sercarz, E.E.2
  • 67
    • 0028102655 scopus 로고
    • High incidence of spontaneous autoimmune encephalomyelitis in immunodeficient anti-myelin basic protein T cell receptor transgenic mice
    • Lafaille JJ, Nagashima K, Katsuki M, Tonegawa S (1994) High incidence of spontaneous autoimmune encephalomyelitis in immunodeficient anti-myelin basic protein T cell receptor transgenic mice. Cell 78:399
    • (1994) Cell , vol.78 , pp. 399
    • Lafaille, J.J.1    Nagashima, K.2    Katsuki, M.3    Tonegawa, S.4
  • 68
    • 0025037062 scopus 로고
    • Inhibition of experimental autoimmune encephalomyelitis induction in SJL/J mice by using a peptide with high affinity for IAs molecules
    • Lamont AG, Sette A, Fujinami R, Colon SM, Miles C, Grey HM (1990) Inhibition of experimental autoimmune encephalomyelitis induction in SJL/J mice by using a peptide with high affinity for IAs molecules. J Immunol 145:1687
    • (1990) J Immunol , vol.145 , pp. 1687
    • Lamont, A.G.1    Sette, A.2    Fujinami, R.3    Colon, S.M.4    Miles, C.5    Grey, H.M.6
  • 69
    • 0027422993 scopus 로고
    • Induction of nitric oxide synthase activity in human astrocytes by interleukin-1β and interferon-γ
    • Lee SC, Dickson DW, Liu W, Brosnan CF (1993) Induction of nitric oxide synthase activity in human astrocytes by interleukin-1β and interferon-γ. J Neuroimmunol 46:19
    • (1993) J Neuroimmunol , vol.46 , pp. 19
    • Lee, S.C.1    Dickson, D.W.2    Liu, W.3    Brosnan, C.F.4
  • 70
    • 0028966091 scopus 로고
    • Prevention of experimental autoimmune encephalomyelitis by antibodies against interleukin 12
    • Leonard JP, Waldburger KE, Goldman SJ (1995) Prevention of experimental autoimmune encephalomyelitis by antibodies against interleukin 12. J Exp Med 181:381
    • (1995) J Exp Med , vol.181 , pp. 381
    • Leonard, J.P.1    Waldburger, K.E.2    Goldman, S.J.3
  • 71
    • 0024996547 scopus 로고
    • Characterization of measles virus-induced cellular autoimmune reactions against myelin basic protein in Lewis rats
    • Liebert UG, Hashim GA, ter Meulen V (1990) Characterization of measles virus-induced cellular autoimmune reactions against myelin basic protein in Lewis rats. J Neuroimmunol 29:139
    • (1990) J Neuroimmunol , vol.29 , pp. 139
    • Liebert, U.G.1    Hashim, G.A.2    Ter Meulen, V.3
  • 73
    • 0023931606 scopus 로고
    • Augmentation of demyelination in rat acute allergic encephalomyelitis by circulating mouse monoclonal antibodies directed against a myelin/oligodendrocyte glycoprotein
    • Linington C, Bradl M, Lassmann H, Brunner C, Vass K (1988) Augmentation of demyelination in rat acute allergic encephalomyelitis by circulating mouse monoclonal antibodies directed against a myelin/oligodendrocyte glycoprotein. Am J Pathol 130:443
    • (1988) Am J Pathol , vol.130 , pp. 443
    • Linington, C.1    Bradl, M.2    Lassmann, H.3    Brunner, C.4    Vass, K.5
  • 74
    • 0017273551 scopus 로고
    • Theiler's virus-induced demyelination - Prevention by immunosuppression
    • Lipton HL, Dal Canto MC (1976) Theiler's virus-induced demyelination - prevention by immunosuppression. Science 192:62
    • (1976) Science , vol.192 , pp. 62
    • Lipton, H.L.1    Dal Canto, M.C.2
  • 75
    • 0024363480 scopus 로고
    • Control of experimental autoimmune encephalomyelitis by T cells responding to activated T cells
    • Lohse AW, Mor F, Karin N, Cohen IR (1989) Control of experimental autoimmune encephalomyelitis by T cells responding to activated T cells. Science 244:820
    • (1989) Science , vol.244 , pp. 820
    • Lohse, A.W.1    Mor, F.2    Karin, N.3    Cohen, I.R.4
  • 76
    • 0024997357 scopus 로고
    • Fine specificity and HLA restriction of myelin basic protein-specific cytotoxic T cell lines from multiple sclerosis patients and healthy individuals
    • Martin R, Jaraquemada D, Flerlage M, Richert J, Whitaker J, Long FO, McFarlin DE, McFarland HF (1990) Fine specificity and HLA restriction of myelin basic protein-specific cytotoxic T cell lines from multiple sclerosis patients and healthy individuals. J Immunol 145:540
    • (1990) J Immunol , vol.145 , pp. 540
    • Martin, R.1    Jaraquemada, D.2    Flerlage, M.3    Richert, J.4    Whitaker, J.5    Long, F.O.6    McFarlin, D.E.7    McFarland, H.F.8
  • 79
    • 0025954728 scopus 로고
    • Immunosuppressive activity of 13-cis-retinoic acid and prevention of experimental autoimmune encephalomyelitis in rats
    • Massacesi L, Castigli E, Vergelli M, Olivotto J, Abbamondi AL, Sarlo F, Amaducci L (1991) Immunosuppressive activity of 13-cis-retinoic acid and prevention of experimental autoimmune encephalomyelitis in rats. J Clin Invest 88:1331
    • (1991) J Clin Invest , vol.88 , pp. 1331
    • Massacesi, L.1    Castigli, E.2    Vergelli, M.3    Olivotto, J.4    Abbamondi, A.L.5    Sarlo, F.6    Amaducci, L.7
  • 80
    • 0022970450 scopus 로고
    • Interaction between myelin basic protein-sensitized T lymphocytes and murine cerebral vascular endothelial cells
    • McCarron RM, Spatz M, Kempski O, Hogan RN, Muehl L, McFarlin DE (1986) Interaction between myelin basic protein-sensitized T lymphocytes and murine cerebral vascular endothelial cells. J Immunol 137:3428
    • (1986) J Immunol , vol.137 , pp. 3428
    • McCarron, R.M.1    Spatz, M.2    Kempski, O.3    Hogan, R.N.4    Muehl, L.5    McFarlin, D.E.6
  • 81
    • 0025009356 scopus 로고
    • Class II major histocompatibility complex antigen expression in central nervous system: Microglia, astrocytes and endothelial cells
    • Johansson BB, Owman CO, Widmer H (eds), Elsevier, Amsterdam
    • McCarron RM, Tanaka M, Spatz M (1990) Class II major histocompatibility complex antigen expression in central nervous system: microglia, astrocytes and endothelial cells. In: Pathophysiology of the blood-brain barrier. Johansson BB, Owman CO, Widmer H (eds), Elsevier, Amsterdam, pp467-484
    • (1990) Pathophysiology of the Blood-brain Barrier , pp. 467-484
    • McCarron, R.M.1    Tanaka, M.2    Spatz, M.3
  • 82
    • 0027407956 scopus 로고
    • Cytokine-regulated adhesion between encephalitogenic T lymphocytes and ccrebrovascular endothelial cells
    • McCarron RM, Wang L, Racke MK, McFarlin DE, Spatz M (1993) Cytokine-regulated adhesion between encephalitogenic T lymphocytes and ccrebrovascular endothelial cells. J Neuroimmunol 43:23
    • (1993) J Neuroimmunol , vol.43 , pp. 23
    • McCarron, R.M.1    Wang, L.2    Racke, M.K.3    McFarlin, D.E.4    Spatz, M.5
  • 84
    • 0027380361 scopus 로고
    • Inhibition of experimental autoimmune encephalomyelitis by inhalation but not oral administration of the encephalitogenic peptide: Influence of MHC binding affinity
    • Metzler B, Wraith DC (1993) Inhibition of experimental autoimmune encephalomyelitis by inhalation but not oral administration of the encephalitogenic peptide: influence of MHC binding affinity. Int Immunol 5:1159
    • (1993) Int Immunol , vol.5 , pp. 1159
    • Metzler, B.1    Wraith, D.C.2
  • 85
    • 0026542168 scopus 로고
    • Suppressor T cells generated by oral tolerization to myelin basic protein suppress both in vitro and in vivo immune responses by the release of transforming growth factor beta after antigen-specific triggering
    • Miller A, Lider O, Roberts AB, Sporn MB, Weiner HL (1992) Suppressor T cells generated by oral tolerization to myelin basic protein suppress both in vitro and in vivo immune responses by the release of transforming growth factor beta after antigen-specific triggering. Proc Natl Acad Sci USA 89:421
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 421
    • Miller, A.1    Lider, O.2    Roberts, A.B.3    Sporn, M.B.4    Weiner, H.L.5
  • 87
    • 0027448605 scopus 로고
    • The major histocompatibility complex influences myelin basic protein 63-88-induced T cell cytokine profile and experimental autoimmune encephalomyelitis
    • Mustafa M, Vingsbo C, Olsson T, Ljungdahl Å, Höjeberg B, Holmdahl R (1993) The major histocompatibility complex influences myelin basic protein 63-88-induced T cell cytokine profile and experimental autoimmune encephalomyelitis. Eur J Immunol 23:3089
    • (1993) Eur J Immunol , vol.23 , pp. 3089
    • Mustafa, M.1    Vingsbo, C.2    Olsson, T.3    Ljungdahl, Å.4    Höjeberg, B.5    Holmdahl, R.6
  • 89
    • 0025969733 scopus 로고
    • T cell receptor peptide therapy triggers autoregulation of experimental encephalomyelitis
    • Offner H, Hashim GA, Vandenbark AA (1991) T cell receptor peptide therapy triggers autoregulation of experimental encephalomyelitis. Science 251:430
    • (1991) Science , vol.251 , pp. 430
    • Offner, H.1    Hashim, G.A.2    Vandenbark, A.A.3
  • 93
    • 0025906789 scopus 로고
    • Expression of vascular addressins and ICAM-1 by endothelial cells in the spinal cord during chronic relapsing experimental allergic encephalomyelitis in the Biozzi AB/H mouse
    • O'Neill JK, Butter C, Baker D, Gschmeissner SE, Kraal G, Butcher EC (1991) Expression of vascular addressins and ICAM-1 by endothelial cells in the spinal cord during chronic relapsing experimental allergic encephalomyelitis in the Biozzi AB/H mouse. Immunology 72:520
    • (1991) Immunology , vol.72 , pp. 520
    • O'Neill, J.K.1    Butter, C.2    Baker, D.3    Gschmeissner, S.E.4    Kraal, G.5    Butcher, E.C.6
  • 94
    • 0025370870 scopus 로고
    • T-cell recognition of an immunodominant myelin basic protein epitope in multiple sclerosis
    • Ota K, Matsui M, Milford EL, Mackin GA, Weiner HL, Hafler DA (1990) T-cell recognition of an immunodominant myelin basic protein epitope in multiple sclerosis. Nature 346:183
    • (1990) Nature , vol.346 , pp. 183
    • Ota, K.1    Matsui, M.2    Milford, E.L.3    Mackin, G.A.4    Weiner, H.L.5    Hafler, D.A.6
  • 95
    • 0024267683 scopus 로고
    • Protection from experimental allergic encephalomyelitis conferred by a monoclonal antibody directed against a shared idiotype on rat T cell receptors specific for myelin basic protein
    • Owhashi M, Heber-Katz E (1989) Protection from experimental allergic encephalomyelitis conferred by a monoclonal antibody directed against a shared idiotype on rat T cell receptors specific for myelin basic protein. J Exp Med 168:2153
    • (1989) J Exp Med , vol.168 , pp. 2153
    • Owhashi, M.1    Heber-Katz, E.2
  • 96
    • 0023221133 scopus 로고
    • Treatment of multiple sclerosis with gamma interferon: Exacerbations associated with activation of the immune system
    • Panitch HS, Hirsch RL, Schindler J, Johnson KP (1987) Treatment of multiple sclerosis with gamma interferon: exacerbations associated with activation of the immune system. Neurology 37:1097
    • (1987) Neurology , vol.37 , pp. 1097
    • Panitch, H.S.1    Hirsch, R.L.2    Schindler, J.3    Johnson, K.P.4
  • 97
    • 0027521002 scopus 로고
    • Interferon beta-1b is effective in relapsing-remitting multiple sclerosis. II. MRI analysis results of a multicenter. randomized, double-blind, placebo-controlled trial
    • Paty DW, Li DKB, the UBC MS/MRI Study Group and the JFNB MS Study Group (1993) Interferon beta-1b is effective in relapsing-remitting multiple sclerosis. II. MRI analysis results of a multicenter. randomized, double-blind, placebo-controlled trial. Neurology 43:662
    • (1993) Neurology , vol.43 , pp. 662
    • Paty, D.W.1    Li, D.K.B.2
  • 100
    • 0001612484 scopus 로고
    • The neuropathology of multiple sclerosis
    • Prineas JW (1985) The neuropathology of multiple sclerosis. Handb Clin Neurol 47:213
    • (1985) Handb Clin Neurol , vol.47 , pp. 213
    • Prineas, J.W.1
  • 101
    • 0025892475 scopus 로고
    • Prevention and treatment of chronic relapsing experimental allergic encephalomyelitis by transforming growth factor-β1
    • Racke MK, Dhib-Jalbut S, Cannella B, Albert PS, Raine CS, McFarlin DE (1991) Prevention and treatment of chronic relapsing experimental allergic encephalomyelitis by transforming growth factor-β1. J Immunol 146:3012
    • (1991) J Immunol , vol.146 , pp. 3012
    • Racke, M.K.1    Dhib-Jalbut, S.2    Cannella, B.3    Albert, P.S.4    Raine, C.S.5    McFarlin, D.E.6
  • 102
    • 0026583488 scopus 로고
    • Evidence of endogenous regulatory function of transforming growth factor-β1 in experimental allergic encephalomyelitis
    • Racke MK, Cannella B, Albert P, Sporn M, Raine CS, McFarlin DE (1992a) Evidence of endogenous regulatory function of transforming growth factor-β1 in experimental allergic encephalomyelitis. Int Immunol 4:615
    • (1992) Int Immunol , vol.4 , pp. 615
    • Racke, M.K.1    Cannella, B.2    Albert, P.3    Sporn, M.4    Raine, C.S.5    McFarlin, D.E.6
  • 103
    • 0026599446 scopus 로고
    • Copolymer-1-induced inhibition of antigen-specific T cell activation: Interference with antigen presentation
    • Racke MK, Martin R, McFarland HF, Fritz RB (1992) Copolymer-1-induced inhibition of antigen-specific T cell activation: interference with antigen presentation. J Neuroimmunol 37:75
    • (1992) J Neuroimmunol , vol.37 , pp. 75
    • Racke, M.K.1    Martin, R.2    McFarland, H.F.3    Fritz, R.B.4
  • 104
    • 0027422999 scopus 로고
    • Long-term treatment of chronic relapsing experimental allergic encephalomyelitis by transforming growth factor-β2
    • Racke MK, Sriram S, Carlino J, Cannella B, Raine CS, McFarlin DE (1993) Long-term treatment of chronic relapsing experimental allergic encephalomyelitis by transforming growth factor-β2. J Neuroimmunol 46:175
    • (1993) J Neuroimmunol , vol.46 , pp. 175
    • Racke, M.K.1    Sriram, S.2    Carlino, J.3    Cannella, B.4    Raine, C.S.5    McFarlin, D.E.6
  • 106
    • 0028296055 scopus 로고
    • Superantigen modulation of experimental allergic encephalomyelitis: Activation or anergy determines outcome
    • Racke MK, Quigley L, Cannella B, Raine CS, McFarlin DE, Scott DE (1994) Superantigen modulation of experimental allergic encephalomyelitis: activation or anergy determines outcome. J Immunol 152:2051
    • (1994) J Immunol , vol.152 , pp. 2051
    • Racke, M.K.1    Quigley, L.2    Cannella, B.3    Raine, C.S.4    McFarlin, D.E.5    Scott, D.E.6
  • 108
    • 0003110820 scopus 로고
    • Multiple sclerosis and chronic relapsing EAE: Comparative ultrastructural neuropathology
    • Hallpike JF, Adams CW, Tourtelotte WW (eds). Williams & Wilkins, Baltimore
    • Raine CS (1983) Multiple sclerosis and chronic relapsing EAE: comparative ultrastructural neuropathology. In: Hallpike JF, Adams CW, Tourtelotte WW (eds) Multiple sclerosis. Williams & Wilkins, Baltimore, pp 413-178
    • (1983) Multiple Sclerosis , pp. 413-1178
    • Raine, C.S.1
  • 109
    • 0024245664 scopus 로고
    • On the immunopathology of plaque development and repair in multiple sclerosis
    • Raine CS, Scheinberg LC (1988) On the immunopathology of plaque development and repair in multiple sclerosis. J Neuroimmunol 20:189
    • (1988) J Neuroimmunol , vol.20 , pp. 189
    • Raine, C.S.1    Scheinberg, L.C.2
  • 110
    • 0025168906 scopus 로고
    • Homing to central nervous system vasculature by antigen-specific lymphocytes. II. Lymphocyte/endothelial cell adhesion during the initial stages of autoimmune demyelination
    • Raine CS, Cannella B, Duijvestijn AM, Cross AH (1990) Homing to central nervous system vasculature by antigen-specific lymphocytes. II. Lymphocyte/endothelial cell adhesion during the initial stages of autoimmune demyelination. Lab Invest 63:476
    • (1990) Lab Invest , vol.63 , pp. 476
    • Raine, C.S.1    Cannella, B.2    Duijvestijn, A.M.3    Cross, A.H.4
  • 111
    • 0028983573 scopus 로고
    • TNF-α expression by resident microglia and infiltrating leukocytes in the central nervous system of mice with experimental encephalomyelitis
    • Renno T, Krakowski M, Piccirillo C, Lin J, Owens T (1995) TNF-α expression by resident microglia and infiltrating leukocytes in the central nervous system of mice with experimental encephalomyelitis. J Immunol 154:944
    • (1995) J Immunol , vol.154 , pp. 944
    • Renno, T.1    Krakowski, M.2    Piccirillo, C.3    Lin, J.4    Owens, T.5
  • 113
    • 0026510786 scopus 로고
    • Protection from experimental allergic encephalomyelitis by application of a bacterial superantigen
    • Rott O, Wekerle H, Fleischer B (1992) Protection from experimental allergic encephalomyelitis by application of a bacterial superantigen. Int Immunol 4:347
    • (1992) Int Immunol , vol.4 , pp. 347
    • Rott, O.1    Wekerle, H.2    Fleischer, B.3
  • 114
    • 0027273042 scopus 로고
    • Phosphodiesterase inhibitor pentoxifylline, a selective suppressor of T helper type1- But not type 2-associated lymphokine production, prevents induction of experimental autoimmune encephalomyelitis in Lewis rats
    • Rott O, Cash E, Fleischer B (1993) Phosphodiesterase inhibitor pentoxifylline, a selective suppressor of T helper type1- but not type 2-associated lymphokine production, prevents induction of experimental autoimmune encephalomyelitis in Lewis rats. Eur J Immunol 23:1745
    • (1993) Eur J Immunol , vol.23 , pp. 1745
    • Rott, O.1    Cash, E.2    Fleischer, B.3
  • 115
    • 0028245010 scopus 로고
    • Interleukin-10 prevents experimental allergic encephalomyelitis in rats
    • Rott O, Fleischer B, Cash E (1994) Interleukin-10 prevents experimental allergic encephalomyelitis in rats. Eur J Immunol 24:1434
    • (1994) Eur J Immunol , vol.24 , pp. 1434
    • Rott, O.1    Fleischer, B.2    Cash, E.3
  • 118
    • 0022242651 scopus 로고
    • Autoaggressive T lymphocyte lines recognize the encephalitogenic region of myelin basic protein; in vitro selection from unprimed rat T lymphocyte populations
    • Schlüsener H, Wekerle H (1985) Autoaggressive T lymphocyte lines recognize the encephalitogenic region of myelin basic protein; in vitro selection from unprimed rat T lymphocyte populations. J Immunol 135:3128
    • (1985) J Immunol , vol.135 , pp. 3128
    • Schlüsener, H.1    Wekerle, H.2
  • 119
    • 0027773017 scopus 로고
    • Apoptosis of T lymphocytes in experimental autoimmune encephalomyelitis: Evidence for programmed cell death as a mechanism to control inflammation in the brain
    • Schmied M, Breitschopf H, Gold R, Zischler H, Rothe G, Wekerle H, Lassmann H (1993) Apoptosis of T lymphocytes in experimental autoimmune encephalomyelitis: Evidence for programmed cell death as a mechanism to control inflammation in the brain. Amer. J Pathology 143:446
    • (1993) Amer. J Pathology , vol.143 , pp. 446
    • Schmied, M.1    Breitschopf, H.2    Gold, R.3    Zischler, H.4    Rothe, G.5    Wekerle, H.6    Lassmann, H.7
  • 120
    • 0023904746 scopus 로고
    • Tumor necrosis factor mediates myelin and oligodendrocyte damage in vitro
    • Selmaj K, Raine CS (1988) Tumor necrosis factor mediates myelin and oligodendrocyte damage in vitro. Ann Neurol 23:339
    • (1988) Ann Neurol , vol.23 , pp. 339
    • Selmaj, K.1    Raine, C.S.2
  • 121
    • 0026094706 scopus 로고
    • Anti-tumor necrosis factor therapy abrogates autoimmune demyelination
    • Selmaj K, Raine CS, Cross AH (1991) Anti-tumor necrosis factor therapy abrogates autoimmune demyelination. Ann Neurol 30:694
    • (1991) Ann Neurol , vol.30 , pp. 694
    • Selmaj, K.1    Raine, C.S.2    Cross, A.H.3
  • 122
    • 0027315234 scopus 로고
    • The specific type IV phosphodiesterase inhibitor rolipram suppresses tumor necrosis factor-alpha production by human mononuclear cells
    • Semmler J, Wachtel H, Endres S (1993) The specific type IV phosphodiesterase inhibitor rolipram suppresses tumor necrosis factor-alpha production by human mononuclear cells. Int J Immunopharmacol 15:409
    • (1993) Int J Immunopharmacol , vol.15 , pp. 409
    • Semmler, J.1    Wachtel, H.2    Endres, S.3
  • 125
    • 0025773147 scopus 로고
    • Association between tumor necrosis factor-α and disease progression in chronic progressive multiple sclerosis
    • Sharief MK, Hentges R (1991) Association between tumor necrosis factor-α and disease progression in chronic progressive multiple sclerosis. New Engl. J Med 325:467
    • (1991) New Engl. J Med , vol.325 , pp. 467
    • Sharief, M.K.1    Hentges, R.2
  • 126
    • 0026335737 scopus 로고
    • Antigen-specific therapy of experimental allergic encephalomyelitis by soluble class II major histocompatibility complex-peptide complexes
    • Sharma SD, Nag B, Su XM, Spack E, Clark BR, Sriram S (1991) Antigen-specific therapy of experimental allergic encephalomyelitis by soluble class II major histocompatibility complex-peptide complexes. Proc Natl Acad Sci USA 88:11465
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 11465
    • Sharma, S.D.1    Nag, B.2    Su, X.M.3    Spack, E.4    Clark, B.R.5    Sriram, S.6
  • 127
    • 0025995510 scopus 로고
    • A single amino acid change in a myelin basic protein peptide confers the capacity to prevent rather than induce experimental autoimmune encephalomyelitis
    • Smilek DE, Wraith DC, Hodgkinson S, Dwevedy S, Steinman L, McDevitt HO (1991) A single amino acid change in a myelin basic protein peptide confers the capacity to prevent rather than induce experimental autoimmune encephalomyelitis. Proc Natl Acad Sci USA 88:9633
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 9633
    • Smilek, D.E.1    Wraith, D.C.2    Hodgkinson, S.3    Dwevedy, S.4    Steinman, L.5    McDevitt, H.O.6
  • 128
    • 0025301596 scopus 로고
    • Intercellular adhesion molecule-1 (ICAM-1) in cellular immune reactions in the human central nervous system
    • Sobel RA, Mitchell ME, Fondren G (1990) Intercellular adhesion molecule-1 (ICAM-1) in cellular immune reactions in the human central nervous system. Am J Path 136:1309
    • (1990) Am J Path , vol.136 , pp. 1309
    • Sobel, R.A.1    Mitchell, M.E.2    Fondren, G.3
  • 131
    • 0019642389 scopus 로고
    • In vivo effects of antibodies to immune response gene products: Prevention of experimental allergic encephalomyelitis
    • Steinman L, Rosenbaum J, Sriram S, McDevitt HO (1981) In vivo effects of antibodies to immune response gene products: Prevention of experimental allergic encephalomyelitis. Proc Natl Acad Sci USA 78:7111
    • (1981) Proc Natl Acad Sci USA , vol.78 , pp. 7111
    • Steinman, L.1    Rosenbaum, J.2    Sriram, S.3    McDevitt, H.O.4
  • 132
    • 0023904339 scopus 로고
    • Suppression of experimentally induced autoimmune encephalomyelitis by cytotoxic T-T cell interactions
    • Sun D, Qin Y, Chluba J, Epplen JT, Wekerle H (1988) Suppression of experimentally induced autoimmune encephalomyelitis by cytotoxic T-T cell interactions. Nature 332:843
    • (1988) Nature , vol.332 , pp. 843
    • Sun, D.1    Qin, Y.2    Chluba, J.3    Epplen, J.T.4    Wekerle, H.5
  • 133
    • 0028170995 scopus 로고
    • Apoptotic elimination of Vβ8.2+ cells from the central nervous system during recovery from experimental autoimmune encephalomyelitis induced by the passive transfer of Vβ8.2+ encephalitogenic T cells
    • Tabi Z, McCombe P, Pender MP (1994) Apoptotic elimination of Vβ8.2+ cells from the central nervous system during recovery from experimental autoimmune encephalomyelitis induced by the passive transfer of Vβ8.2+ encephalitogenic T cells. Eur J Immunol 24:2609
    • (1994) Eur J Immunol , vol.24 , pp. 2609
    • Tabi, Z.1    McCombe, P.2    Pender, M.P.3
  • 134
    • 0025990276 scopus 로고
    • Successful treatment of paralytic relapses in adoptive experimental autoimmune encephalomyelitis via neuroantigen-specific tolerance
    • Tan LJ, Kennedy MK, Dal CM, Miller SD (1991) Successful treatment of paralytic relapses in adoptive experimental autoimmune encephalomyelitis via neuroantigen-specific tolerance. J Immunol 147:1797
    • (1991) J Immunol , vol.147 , pp. 1797
    • Tan, L.J.1    Kennedy, M.K.2    Dal, C.M.3    Miller, S.D.4
  • 135
    • 0026557522 scopus 로고
    • Regulation of the effector stages of experimental autoimmune encephalomyelitis via neuroantigen-specific tolerance induction. II. Fine specificity of effector T cell inhibition
    • Tan LJ, Kennedy MK, Miller SD (1992) Regulation of the effector stages of experimental autoimmune encephalomyelitis via neuroantigen-specific tolerance induction. II. Fine specificity of effector T cell inhibition. J Immunol 148:2748
    • (1992) J Immunol , vol.148 , pp. 2748
    • Tan, L.J.1    Kennedy, M.K.2    Miller, S.D.3
  • 136
    • 0024267426 scopus 로고
    • Specific inhibition of the T-cell response to myelin basic protein by the synthetic copolymer Cop-1
    • Teitelbaum D, Aharoni R, Arnon R, Sela M (1988) Specific inhibition of the T-cell response to myelin basic protein by the synthetic copolymer Cop-1. Proc Natl Acad Sci USA 85:9724
    • (1988) Proc Natl Acad Sci USA , vol.85 , pp. 9724
    • Teitelbaum, D.1    Aharoni, R.2    Arnon, R.3    Sela, M.4
  • 138
    • 0027418515 scopus 로고
    • Interferon beta-1b is effective in relapsing-remitting multiple sclerosis. I. Clinical results of a multicenter, randomized, double-blind, placebo-controlled trial
    • The IFNB Multiple Sclerosis Study Group (1993) Interferon beta-1b is effective in relapsing-remitting multiple sclerosis. I. Clinical results of a multicenter, randomized, double-blind, placebo-controlled trial. Neurology 43:655
    • (1993) Neurology , vol.43 , pp. 655
  • 139
    • 0028059264 scopus 로고
    • A synthetic peptide from the third hypervariable region of major histocompatibility complex class II β chain as a vaccine for treatment of experimental autoimmune encephalomyelitis
    • Topham DJ, Nag B, Arimilli S, Sriram S (1994) A synthetic peptide from the third hypervariable region of major histocompatibility complex class II β chain as a vaccine for treatment of experimental autoimmune encephalomyelitis. Proc Natl Acad Sci USA 91:8005
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 8005
    • Topham, D.J.1    Nag, B.2    Arimilli, S.3    Sriram, S.4
  • 140
    • 0023740105 scopus 로고
    • A synthetic peptide from myelin proteolipid protein induces experimental allergic encephalomyelitis
    • Tuohy VK, Lu Z, Sobel RA, Laursen RA, Lees MB (1988) A synthetic peptide from myelin proteolipid protein induces experimental allergic encephalomyelitis. J Immunol 141:1126
    • (1988) J Immunol , vol.141 , pp. 1126
    • Tuohy, V.K.1    Lu, Z.2    Sobel, R.A.3    Laursen, R.A.4    Lees, M.B.5
  • 141
    • 0023751365 scopus 로고
    • Restricted use of the T cells receptor V genes in murine autoimmune encephalomyelitis raises possibilities for antibody therapy
    • Urban JL, Kumar V, Kono DH, Gomez C, Horvath SJ, Clayton J, Ando DL, Sercarz EE, Hood L (1988) Restricted use of the T cells receptor V genes in murine autoimmune encephalomyelitis raises possibilities for antibody therapy. Cell 54:577
    • (1988) Cell , vol.54 , pp. 577
    • Urban, J.L.1    Kumar, V.2    Kono, D.H.3    Gomez, C.4    Horvath, S.J.5    Clayton, J.6    Ando, D.L.7    Sercarz, E.E.8    Hood, L.9
  • 142
    • 0027170328 scopus 로고
    • Skewed T cell receptor repertoire in genetically identical twins with multiple sclerosis correlates with disease
    • Utz U, Biddison WE, McFarland HF, McFarlin DE, Flerlage M, Martin R (1993) Skewed T cell receptor repertoire in genetically identical twins with multiple sclerosis correlates with disease. Nature 364:243
    • (1993) Nature , vol.364 , pp. 243
    • Utz, U.1    Biddison, W.E.2    McFarland, H.F.3    McFarlin, D.E.4    Flerlage, M.5    Martin, R.6
  • 143
    • 0028283994 scopus 로고
    • Heterogeneity of T-cell receptor α-chain complementarity-determining region 3 in myelin basic protein-specific T cells increases with severity of multiple sclerosis
    • Utz U, Brooks JA, McFarland HF, Martin R, Biddison WE (1994) Heterogeneity of T-cell receptor α-chain complementarity-determining region 3 in myelin basic protein-specific T cells increases with severity of multiple sclerosis. Proc Natl Acad Sci USA 91:5567
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 5567
    • Utz, U.1    Brooks, J.A.2    McFarland, H.F.3    Martin, R.4    Biddison, W.E.5
  • 144
    • 0024425273 scopus 로고
    • Immunization with a synthetic T-cell receptor V-region peptide against experimental autoimmune encephalomyelitis
    • Vandenbark AA, Hashim G, Offner H (1989) Immunization with a synthetic T-cell receptor V-region peptide against experimental autoimmune encephalomyelitis. Nature 341:541
    • (1989) Nature , vol.341 , pp. 541
    • Vandenbark, A.A.1    Hashim, G.2    Offner, H.3
  • 147
    • 0021058052 scopus 로고
    • Adoptive transfer of EAE-like lesions from rats with coronavirus-induced demyelinating encephalomyelitis
    • Watanabe R, Wege H, Meulen V ter (1983) Adoptive transfer of EAE-like lesions from rats with coronavirus-induced demyelinating encephalomyelitis. Nature 305:150
    • (1983) Nature , vol.305 , pp. 150
    • Watanabe, R.1    Wege, H.2    Ter Meulen, V.3
  • 148
    • 0027467440 scopus 로고
    • Double-blind pilot trial of oral tolerization with myelin antigens in multiple sclerosis
    • Weiner HL, Mackin GA, Matsui M, Orav EJ, Khoury SJ, Dawson DM, Hafler DA (1993) Double-blind pilot trial of oral tolerization with myelin antigens in multiple sclerosis. Science 259:1321
    • (1993) Science , vol.259 , pp. 1321
    • Weiner, H.L.1    Mackin, G.A.2    Matsui, M.3    Orav, E.J.4    Khoury, S.J.5    Dawson6
  • 150
    • 0027400491 scopus 로고
    • Augmentation of adoptively transferred experimental allergic encephalomyelitis by administration of a monoclonal antibody specific for LFA-1α
    • Welsh CT, Rose JW, Hill KE, Townsend JJ (1993) Augmentation of adoptively transferred experimental allergic encephalomyelitis by administration of a monoclonal antibody specific for LFA-1α. J Neuroimmunol 43:161
    • (1993) J Neuroimmunol , vol.43 , pp. 161
    • Welsh, C.T.1    Rose, J.W.2    Hill, K.E.3    Townsend, J.J.4
  • 151
    • 0027440847 scopus 로고
    • Correlation between susceptibility to demyelination and interferon-γ induction of major histocompatibility complex class II antigens on murine cerebrovascular endothelial cells
    • Welsh J, Sapatino B, Rosenbaum B, Smith R, Linthicum S (1993) Correlation between susceptibility to demyelination and interferon-γ induction of major histocompatibility complex class II antigens on murine cerebrovascular endothelial cells. J Neuroimmunol 48:91
    • (1993) J Neuroimmunol , vol.48 , pp. 91
    • Welsh, J.1    Sapatino, B.2    Rosenbaum, B.3    Smith, R.4    Linthicum, S.5
  • 152
    • 0025115641 scopus 로고
    • Endothelial cell expression of the intercellular adhesion molecule-1 (ICAM-1) in the central nervous system of guinea pigs during acute and chronic relapsing experimental allergic encephalomyelitis
    • Wilcox CE, Ward AMV, Evans A, Baker D, Rothlein R, Turk JL (1990) Endothelial cell expression of the intercellular adhesion molecule-1 (ICAM-1) in the central nervous system of guinea pigs during acute and chronic relapsing experimental allergic encephalomyelitis. J Neuroimmunol 30:43
    • (1990) J Neuroimmunol , vol.30 , pp. 43
    • Wilcox, C.E.1    Ward, A.M.V.2    Evans, A.3    Baker, D.4    Rothlein, R.5    Turk, J.L.6
  • 153
    • 0005064866 scopus 로고
    • Switch of autoreactive human T cell clones from a Th2 to a TGFβ1 secreting phenotype with low affinity T-cell receptor stimulating peptide/MHC complex
    • Windhagen A, Scholz C, Fukaura H, Sette A, Hafler DA (1994) Switch of autoreactive human T cell clones from a Th2 to a TGFβ1 secreting phenotype with low affinity T-cell receptor stimulating peptide/MHC complex. J Neuroimmunol 54:206
    • (1994) J Neuroimmunol , vol.54 , pp. 206
    • Windhagen, A.1    Scholz, C.2    Fukaura, H.3    Sette, A.4    Hafler, D.A.5
  • 155
    • 0021329785 scopus 로고
    • Effect of cloned interferon-γ on expression of H-2 and Ia antigen on cell lines of hemopoietic, lymphoid, epithelial, fibroblastic and neuronal origin
    • Wong GHW, Clark-Lewis J, Harris AW, Schrader JW (1984) Effect of cloned interferon-γ on expression of H-2 and Ia antigen on cell lines of hemopoietic, lymphoid, epithelial, fibroblastic and neuronal origin. Eur J Immunol 14:52
    • (1984) Eur J Immunol , vol.14 , pp. 52
    • Wong, G.H.W.1    Clark-Lewis, J.2    Harris, A.W.3    Schrader, J.W.4
  • 156
    • 0024325672 scopus 로고
    • Antigen recognition in autoimmune encephalomyelitis and the potential for peptide-mediated immunotherapy
    • Wraith DC, Smilek DE, Mitchell DJ, Steinman L, McDevitt HO (1989) Antigen recognition in autoimmune encephalomyelitis and the potential for peptide-mediated immunotherapy. Cell 59:247
    • (1989) Cell , vol.59 , pp. 247
    • Wraith, D.C.1    Smilek, D.E.2    Mitchell, D.J.3    Steinman, L.4    McDevitt, H.O.5
  • 158
    • 0026506799 scopus 로고
    • Prevention of experimental autoimmune encephalomyelitis by antibodies against α4β1 integrin
    • Yednock TA, Cannon C, Fritz LC, Sanchez-Madrid F, Steinman L, Karin N (1992) Prevention of experimental autoimmune encephalomyelitis by antibodies against α4β1 integrin. Nature 356:63
    • (1992) Nature , vol.356 , pp. 63
    • Yednock, T.A.1    Cannon, C.2    Fritz, L.C.3    Sanchez-Madrid, F.4    Steinman, L.5    Karin, N.6
  • 160
    • 0025328989 scopus 로고
    • Prevention and treatment of murine experimental allergic encephalomyelitis with T cell receptor V beta-specific antibodies
    • Zaller DM, Osman G, Kanagawa O, Hood L (1990) Prevention and treatment of murine experimental allergic encephalomyelitis with T cell receptor V beta-specific antibodies. J Exp Med 171:1943
    • (1990) J Exp Med , vol.171 , pp. 1943
    • Zaller, D.M.1    Osman, G.2    Kanagawa, O.3    Hood, L.4
  • 161
    • 0025246367 scopus 로고
    • The T lymphocyte in experimental allergic encephalomyelitis
    • Zamvil SS, Steinman E (1990) The T lymphocyte in experimental allergic encephalomyelitis. Annu Rev Immunol 8:579
    • (1990) Annu Rev Immunol , vol.8 , pp. 579
    • Zamvil, S.S.1    Steinman, E.2
  • 162
    • 0027448708 scopus 로고
    • MHC-restricted depletion of human myelin basic protein-reactive T cells by T cell vaccination
    • Zhang J, Medaer R, Stinissen P, Hafler DA, Raus J (1993) MHC-restricted depletion of human myelin basic protein-reactive T cells by T cell vaccination. Science 261:1451
    • (1993) Science , vol.261 , pp. 1451
    • Zhang, J.1    Medaer, R.2    Stinissen, P.3    Hafler, D.A.4    Raus, J.5
  • 163
    • 0027957780 scopus 로고
    • Increased frequency of interleukin 2-responsive T cells specific for myelin basic protein in peripheral blood and cerebrospinal fluid of patients with multiple sclerosis
    • Zhang J, Markovic-Plese S, Lacet B, Raus J, Weiner HL, Hafler DA (1994) Increased frequency of interleukin 2-responsive T cells specific for myelin basic protein in peripheral blood and cerebrospinal fluid of patients with multiple sclerosis. J Exp Med 179:973
    • (1994) J Exp Med , vol.179 , pp. 973
    • Zhang, J.1    Markovic-Plese, S.2    Lacet, B.3    Raus, J.4    Weiner, H.L.5    Hafler, D.A.6


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