Suppression of inducible nitric oxide synthase expression in RAW 264.7 macrophages by two β-carboline alkaloids extracted from Melia azedarach

European Journal of Pharmacology

Volumn 406, Issue 3, 2000, Pages 301-309

  Lee, Byeong Gon ^a   Kim, Seung Hee ^b   Zee, Ok Pyo ^a   Lee, Kang Ro ^a   Lee, Hoi Young ^c   Han, Jeung Whan ^a   Lee, Hyang Woo ^a  

^a Sungkyunkwan University   (South Korea)

^b Korea Food and Drug Administration   (South Korea)

^c Konyang University   (South Korea)

Author keywords

Carboline alkaloid; Inducible NO synthase; Inflammation; NF B (nuclear factor B); Nitric oxide (NO)

Indexed keywords

4 METHOXY 1 VINYL BETA CARBOLINE; 4,8 DIMETHOXY 1 VINYL BETA CARBOLINE; ALKALOID; BETA CARBOLINE DERIVATIVE; CITRULLINE; CYCLOOXYGENASE 2; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; TRITIUM; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG STRUCTURE; ENZYME INHIBITION; GENE EXPRESSION; INFLAMMATION; MACROPHAGE; MONOCYTE; MOUSE; NONHUMAN; PRIORITY JOURNAL;

ALKALOIDS; ANIMAL; CARBOLINES; CELL LINE; CITRULLINE; DINOPROSTONE; ENZYME INHIBITORS; ISOENZYMES; LIPOPOLYSACCHARIDES; MACROPHAGES; MICE; NF-KAPPA B; NITRIC-OXIDE SYNTHASE; NITRITES; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASE; SUPPORT, NON-U.S. GOV'T;

EID: 0034693256     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(00)00680-4     Document Type: Article

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