메뉴 건너뛰기




Volumn 89, Issue 1, 1997, Pages 33-41

The RNA-DNA hybrid maintains the register of transcription by preventing backtracking of RNA polymerase

Author keywords

[No Author keywords available]

Indexed keywords

RNA POLYMERASE; DNA DIRECTED RNA POLYMERASE; HETERODUPLEX;

EID: 0031552174     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/s0092-8674(00)80180-4     Document Type: Article
Times cited : (387)

References (53)
  • 1
    • 0028316925 scopus 로고
    • RNA cleavage and chain elongation by Escherichia coli DNA-dependent RNA polymerase in a binary enzyme RNA complex
    • Altman, C.R., Solow-Cordero, D.E., and Chamberlin, M.J. (1994). RNA cleavage and chain elongation by Escherichia coli DNA-dependent RNA polymerase in a binary enzyme RNA complex. Proc. Natl. Acad. Sci. USA 91, 3784-3788.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 3784-3788
    • Altman, C.R.1    Solow-Cordero, D.E.2    Chamberlin, M.J.3
  • 2
    • 0029084914 scopus 로고
    • Elongin(SIII): A multisubunit regulator of elongation by RNA polymerase II
    • Aso, T., Lane, W.S., Conaway, J.W., and Conaway, R.C. (1995). Elongin(SIII): a multisubunit regulator of elongation by RNA polymerase II. Science 269, 1439-1443.
    • (1995) Science , vol.269 , pp. 1439-1443
    • Aso, T.1    Lane, W.S.2    Conaway, J.W.3    Conaway, R.C.4
  • 3
    • 0027536870 scopus 로고
    • Transcript cleavage factors from E. coli
    • Borukhov, S., Sagitov, V., and Goldfarb, A. (1993). Transcript cleavage factors from E. coli. Cell 72, 459-466.
    • (1993) Cell , vol.72 , pp. 459-466
    • Borukhov, S.1    Sagitov, V.2    Goldfarb, A.3
  • 4
    • 0028905513 scopus 로고
    • Escherichia coli NusG protein stimulates transcription elongation rates in vivo and in vitro
    • Burova, E., Hung, S.C., Sagitov, V., Stitt, B.L., and Gottesman, M.E. (1995). Escherichia coli NusG protein stimulates transcription elongation rates in vivo and in vitro. J. Bacteriol. 177, 1388-1392.
    • (1995) J. Bacteriol. , vol.177 , pp. 1388-1392
    • Burova, E.1    Hung, S.C.2    Sagitov, V.3    Stitt, B.L.4    Gottesman, M.E.5
  • 5
    • 0027106595 scopus 로고
    • New models for the mechanism of transcription elongation and its regulation
    • Chamberlin, M.J. (1995). New models for the mechanism of transcription elongation and its regulation. Harvey Lect. 88, 1-21.
    • (1995) Harvey Lect. , vol.88 , pp. 1-21
    • Chamberlin, M.J.1
  • 6
    • 0000669319 scopus 로고
    • New perspectives on RNA chain elongation and termination by E. coli RNA polymerase
    • R.C. Conaway and J.W. Conaway, eds. (New York: Raven Press, Ltd.)
    • Chan, C.L., and Landick, R. (1994). New perspectives on RNA chain elongation and termination by E. coli RNA polymerase. In Transcription: Mechanisms and Regulation, R.C. Conaway and J.W. Conaway, eds. (New York: Raven Press, Ltd.), pp. 297-321.
    • (1994) Transcription: Mechanisms and Regulation , pp. 297-321
    • Chan, C.L.1    Landick, R.2
  • 7
    • 0025832171 scopus 로고
    • Three-dimensional structure of yeast RNA polymerase II at 16 å resolution
    • Darst, S.A., Edwards, A.M., Kubalek, E.W., and Kornberg, R.D. (1991). Three-dimensional structure of yeast RNA polymerase II at 16 Å resolution. Cell 66, 21-128.
    • (1991) Cell , vol.66 , pp. 21-128
    • Darst, S.A.1    Edwards, A.M.2    Kubalek, E.W.3    Kornberg, R.D.4
  • 8
    • 0027321585 scopus 로고
    • Control of transcription termination by RNA-binding proteins
    • Das, A. (1993). Control of transcription termination by RNA-binding proteins. Annu. Rev. Biochem. 62, 893-930.
    • (1993) Annu. Rev. Biochem. , vol.62 , pp. 893-930
    • Das, A.1
  • 9
    • 0027761137 scopus 로고
    • Multiple RNA polymerase conformations and GreA: Control of the fidelity of transcription
    • Erie, D.A., Hajiseyedjavadi, O., Young, M.C., and von Hippel, P.H. (1993). Multiple RNA polymerase conformations and GreA: control of the fidelity of transcription. Science 262, 867-873.
    • (1993) Science , vol.262 , pp. 867-873
    • Erie, D.A.1    Hajiseyedjavadi, O.2    Young, M.C.3    Von Hippel, P.H.4
  • 10
    • 0018868661 scopus 로고
    • A model for transcription termination suggested by studies on the trp attenuator in vitro using base analogs
    • Farnham, P.J., and Platt, T. (1980). A model for transcription termination suggested by studies on the trp attenuator in vitro using base analogs. Cell 20, 739-748.
    • (1980) Cell , vol.20 , pp. 739-748
    • Farnham, P.J.1    Platt, T.2
  • 11
  • 12
    • 0020322130 scopus 로고
    • A topological model for transcription based on unwinding angle analysis of E. coli RNA polymerase binary, initiation and ternary complexes
    • Gamper, H.B., and Hearst, J.E. (1982). A topological model for transcription based on unwinding angle analysis of E. coli RNA polymerase binary, initiation and ternary complexes. Cell 29, 81-90.
    • (1982) Cell , vol.29 , pp. 81-90
    • Gamper, H.B.1    Hearst, J.E.2
  • 13
    • 0029055758 scopus 로고
    • Identification of a decay in transcription potential that results in elongation factor dependence of RNA polymerase II
    • Gu, W., and Reines, D. (1995). Identification of a decay in transcription potential that results in elongation factor dependence of RNA polymerase II. J. Biol. Chem. 270, 11238-11244.
    • (1995) J. Biol. Chem. , vol.270 , pp. 11238-11244
    • Gu, W.1    Reines, D.2
  • 14
    • 0029957789 scopus 로고    scopus 로고
    • Increased accommodation of nascent RNA in a product site on RNA polymerase II during arrest
    • Gu, W., Wind, M., and Reines, D. (1996). Increased accommodation of nascent RNA in a product site on RNA polymerase II during arrest. Proc. Natl. Acad. Sci. USA 93, 6935-6940.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 6935-6940
    • Gu, W.1    Wind, M.2    Reines, D.3
  • 15
    • 0031561795 scopus 로고    scopus 로고
    • A model for the mechanism of polymerase translocation
    • Guajardo, R., and Sousa, R. (1997). A model for the mechanism of polymerase translocation. J. Mol. Biol. 265, 8-19.
    • (1997) J. Mol. Biol. , vol.265 , pp. 8-19
    • Guajardo, R.1    Sousa, R.2
  • 16
    • 0345394597 scopus 로고
    • Topography of transcription path: The leading end of nascent RNA through the Escherichia coli transcription complex
    • Hanna, M.M., and Meares, C.F. (1983). Topography of transcription path: the leading end of nascent RNA through the Escherichia coli transcription complex. Proc. Natl. Acad. Sci. USA 80, 4238-4242.
    • (1983) Proc. Natl. Acad. Sci. USA , vol.80 , pp. 4238-4242
    • Hanna, M.M.1    Meares, C.F.2
  • 17
    • 0001736975 scopus 로고
    • Conversion of mono-and oligodeoxyribonucleotides to 5′-triphosphates
    • Hoard, D.E., and Ott, D.G. (1965). Conversion of mono-and oligodeoxyribonucleotides to 5′-triphosphates. J. Am. Chem. Soc. 87, 1785-1789.
    • (1965) J. Am. Chem. Soc. , vol.87 , pp. 1785-1789
    • Hoard, D.E.1    Ott, D.G.2
  • 18
    • 0026648570 scopus 로고
    • The RNA polymerase II ternary complex cleaves the nascent transcript in 3′-5′ direction in the presence of elongation factor SII
    • Izban, M.G., and Luse, D.S. (1992). The RNA polymerase II ternary complex cleaves the nascent transcript in 3′-5′ direction in the presence of elongation factor SII. Genes Dev. 6, 1342-1356.
    • (1992) Genes Dev. , vol.6 , pp. 1342-1356
    • Izban, M.G.1    Luse, D.S.2
  • 19
    • 0027163013 scopus 로고
    • The increment of SII-facilitated transcript cleavage varies dramatically between elongation competent and incompetent RNA polymerase II ternary complexes
    • Izban, M.G., and Luse, D.S. (1993). The increment of SII-facilitated transcript cleavage varies dramatically between elongation competent and incompetent RNA polymerase II ternary complexes. J. Biol. Chem. 268, 12874-12885.
    • (1993) J. Biol. Chem. , vol.268 , pp. 12874-12885
    • Izban, M.G.1    Luse, D.S.2
  • 20
    • 0030475226 scopus 로고    scopus 로고
    • Fidelity of RNA polymerase II transcription controlled by elongations factor TFIIS
    • Jeon, C., and Agarwal, K. (1996). Fidelity of RNA polymerase II transcription controlled by elongations factor TFIIS. Proc. Natl. Acad. Sci. USA 93, 13677-13682.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 13677-13682
    • Jeon, C.1    Agarwal, K.2
  • 21
    • 0028230578 scopus 로고
    • Complexes of yeast RNA polymerase II and RNA are substrates for TFIIS-induced RNA cleavage
    • Johnson, T.L., and Chamberlin, M.J. (1994). Complexes of yeast RNA polymerase II and RNA are substrates for TFIIS-induced RNA cleavage. Cell 77, 217-224.
    • (1994) Cell , vol.77 , pp. 217-224
    • Johnson, T.L.1    Chamberlin, M.J.2
  • 22
    • 0026535863 scopus 로고
    • Structure of transcription elongation complex in vivo
    • Kainz, M., and Roberts, J. (1992). Structure of transcription elongation complex in vivo. Science 255, 838-841.
    • (1992) Science , vol.255 , pp. 838-841
    • Kainz, M.1    Roberts, J.2
  • 23
    • 0027214148 scopus 로고
    • Histidine-tagged RNA polymerase: Dissection of the transcription cycle using immobilized enzyme
    • Kashlev, M., Martin, E., Polyakov, A., Severinov, K., Nikiforov, V., and Goldfarb, A. (1993). Histidine-tagged RNA polymerase: dissection of the transcription cycle using immobilized enzyme. Gene 130, 9-14.
    • (1993) Gene , vol.130 , pp. 9-14
    • Kashlev, M.1    Martin, E.2    Polyakov, A.3    Severinov, K.4    Nikiforov, V.5    Goldfarb, A.6
  • 24
    • 0025723937 scopus 로고
    • RNA polymerase: Regulation of transcript elongation and termination
    • Kerppola, T.K., and Kane, C.M. (1991). RNA polymerase: regulation of transcript elongation and termination. FASEB J. 5, 2833-2842.
    • (1991) FASEB J. , vol.5 , pp. 2833-2842
    • Kerppola, T.K.1    Kane, C.M.2
  • 25
    • 0031059249 scopus 로고    scopus 로고
    • Arrest of transcription: E. coli RNA polymerase translocates backward leaving the 3′ end of the RNA intact and extruded
    • in press
    • Komisarrova, N., and Kashlev, M. (1997a). Arrest of transcription: E. coli RNA polymerase translocates backward leaving the 3′ end of the RNA intact and extruded. Proc. Natl. Acad. Sci. USA 94, in press.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94
    • Komisarrova, N.1    Kashlev, M.2
  • 26
    • 0030950638 scopus 로고    scopus 로고
    • RNA polymerase switches between inactivated and activated states translocating back and forth along the DNA and the RNA
    • in press
    • Komisarrova, N., and Kashlev, M. (1997b). RNA polymerase switches between inactivated and activated states translocating back and forth along the DNA and the RNA. J. Biol. Chem. 272, in press.
    • (1997) J. Biol. Chem. , vol.272
    • Komisarrova, N.1    Kashlev, M.2
  • 27
    • 0026708877 scopus 로고
    • Structural analysis of ternary complexes of Escherichia coli RNA polymerase. Individual complexes halted along different transcription units have distinct and unexpected biochemical properties
    • Krummel, B., and Chamberlin, M.J. (1992). Structural analysis of ternary complexes of Escherichia coli RNA polymerase. Individual complexes halted along different transcription units have distinct and unexpected biochemical properties. J. Mol. Biol. 225, 221-234.
    • (1992) J. Mol. Biol. , vol.225 , pp. 221-234
    • Krummel, B.1    Chamberlin, M.J.2
  • 28
    • 0029983157 scopus 로고    scopus 로고
    • Protein - RNA interactions in the active center of transcription elongation complex
    • Markovtsov, V., Mustaev, A., and Goldfarb, A. (1996). Protein - RNA interactions in the active center of transcription elongation complex. Proc. Natl. Acad. Sci. USA 93, 3221-3226.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 3221-3226
    • Markovtsov, V.1    Mustaev, A.2    Goldfarb, A.3
  • 29
    • 0026703203 scopus 로고
    • Host factor requirements for processive antitermination of transcription and suppression of pausing by the N protein of bacteriophage λ
    • Mason, S.W., Li, J., and Greenblatt, J. (1992). Host factor requirements for processive antitermination of transcription and suppression of pausing by the N protein of bacteriophage λ. J. Biol. Chem. 267, 19418-19426.
    • (1992) J. Biol. Chem. , vol.267 , pp. 19418-19426
    • Mason, S.W.1    Li, J.2    Greenblatt, J.3
  • 30
    • 0028224347 scopus 로고
    • Analysis of RNA chain elongation and termination by saccharomyces cerevisiae RNA polymerase III
    • Matsuzaki, H., Kassavetis, G.A., and Geiduschek, E.P. (1994). Analysis of RNA chain elongation and termination by Saccharomyces cerevisiae RNA polymerase III. J. Mol. Biol. 235, 1173-1192.
    • (1994) J. Mol. Biol. , vol.235 , pp. 1173-1192
    • Matsuzaki, H.1    Kassavetis, G.A.2    Geiduschek, E.P.3
  • 31
    • 0027203950 scopus 로고
    • Active center rearrangement in RNA polymerase initiation complex
    • Mustaev, A., Kashlev, M., Zaychikov, E., Grachev, M., and Goldfarb, A. (1993). Active center rearrangement in RNA polymerase initiation complex. J. Biol. Chem. 268, 19185-19187.
    • (1993) J. Biol. Chem. , vol.268 , pp. 19185-19187
    • Mustaev, A.1    Kashlev, M.2    Zaychikov, E.3    Grachev, M.4    Goldfarb, A.5
  • 33
    • 0028066790 scopus 로고
    • Discontinuous mechanism of transcription elongation
    • Nudler, E., Goldfarb, A., and Kashlev, M. (1994). Discontinuous mechanism of transcription elongation. Science 265, 793-796.
    • (1994) Science , vol.265 , pp. 793-796
    • Nudler, E.1    Goldfarb, A.2    Kashlev, M.3
  • 34
    • 0029066765 scopus 로고
    • Coupling between transcription termination and RNA polymerase inch-worming
    • Nudler, E., Kashlev, M., Nikiforov, V., and Goldfarb, A. (1995). Coupling between transcription termination and RNA polymerase inch-worming. Cell 81, 351-357.
    • (1995) Cell , vol.81 , pp. 351-357
    • Nudler, E.1    Kashlev, M.2    Nikiforov, V.3    Goldfarb, A.4
  • 35
    • 0029818631 scopus 로고    scopus 로고
    • Transcription processivity: RNA polymerase-DNA interactions holding together the elongation complex
    • Nudler, E., Avetissova, E., Markovtsov, V., and Goldfarb, A. (1996). Transcription processivity: RNA polymerase-DNA interactions holding together the elongation complex. Science 273, 211-217.
    • (1996) Science , vol.273 , pp. 211-217
    • Nudler, E.1    Avetissova, E.2    Markovtsov, V.3    Goldfarb, A.4
  • 37
    • 0002605733 scopus 로고    scopus 로고
    • RNA structure in transcription elongation, termination, and antitermination
    • R. Simons and M. Grunberg-Manago, eds. (Cold Spring Harbor, New York: Cold Spring Harbor Laboratory Press), in press
    • Platt, T. (1997). RNA structure in transcription elongation, termination, and antitermination. In RNA Structure and Function, R. Simons and M. Grunberg-Manago, eds. (Cold Spring Harbor, New York: Cold Spring Harbor Laboratory Press), in press.
    • (1997) RNA Structure and Function
    • Platt, T.1
  • 38
    • 0028875725 scopus 로고
    • Three-dimensional structure of E. coli core RNA polymerase: Promoter binding and elongation conformations of the enzyme
    • Polyakov, A., Severinova, E., and Darst, S.A. (1995). Three-dimensional structure of E. coli core RNA polymerase: promoter binding and elongation conformations of the enzyme. Cell 83, 365-373.
    • (1995) Cell , vol.83 , pp. 365-373
    • Polyakov, A.1    Severinova, E.2    Darst, S.A.3
  • 40
    • 0030584091 scopus 로고    scopus 로고
    • Promoter proximal sequences modulate RNA polymerase II elongation by a novel mechanism
    • Reeder, T.C., and Hawley, D.K. (1996). Promoter proximal sequences modulate RNA polymerase II elongation by a novel mechanism. Cell 87, 767-777.
    • (1996) Cell , vol.87 , pp. 767-777
    • Reeder, T.C.1    Hawley, D.K.2
  • 41
    • 0000701273 scopus 로고
    • Transcript elongation and gene regulation in eukaryotes
    • R.C. Conaway and J.W. Conaway, eds. (New York: Raven Press, Ltd.)
    • Reines, D. (1994). Transcript elongation and gene regulation in eukaryotes. In Transcription Mechanisms and Regulation, R.C. Conaway and J.W. Conaway, eds. (New York: Raven Press, Ltd.), pp. 263-278.
    • (1994) Transcription Mechanisms and Regulation , pp. 263-278
    • Reines, D.1
  • 42
    • 0025852478 scopus 로고
    • Footprinting analysis of mammalian RNA polymerase II along its transcript: An alternative view of transcription elongation
    • Rice, G.A., Kane, C.M., and Chamberlin, M.J. (1991). Footprinting analysis of mammalian RNA polymerase II along its transcript: an alternative view of transcription elongation. Proc. Natl. Acad. Sci. USA 88, 4245-4249.
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 4245-4249
    • Rice, G.A.1    Kane, C.M.2    Chamberlin, M.J.3
  • 43
    • 0000882465 scopus 로고    scopus 로고
    • Control of RNA chain elongation and termination
    • F.C. Neidhardt, ed. (Washington, D.C.: American Society for Microbiology)
    • Richardson, J.P., and Greenblatt, J. (1996). Control of RNA chain elongation and termination. In Escherichia coli and Salmonella typhimurium, 2nd Ed., F.C. Neidhardt, ed. (Washington, D.C.: American Society for Microbiology), pp. 822-848.
    • (1996) Escherichia Coli and Salmonella Typhimurium, 2nd Ed. , pp. 822-848
    • Richardson, J.P.1    Greenblatt, J.2
  • 44
    • 0028059269 scopus 로고
    • The active site of RNA polymerase II participates in transcript cleavage within arrested ternary complexes
    • Rudd, M.D., Izban, M.G., and Luse, D.S. (1994). The active site of RNA polymerase II participates in transcript cleavage within arrested ternary complexes. Proc. Natl. Acad. Sci. USA 91, 8057-8061.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 8057-8061
    • Rudd, M.D.1    Izban, M.G.2    Luse, D.S.3
  • 45
    • 0029790806 scopus 로고    scopus 로고
    • Translocation and transcriptional arrest during transcript elongation by RNA polymerase II
    • Samkurashvili, I., and Luse, D.S. (1996).Translocation and transcriptional arrest during transcript elongation by RNA polymerase II. J. Biol. Chem. 277, 23495-23505.
    • (1996) J. Biol. Chem. , vol.277 , pp. 23495-23505
    • Samkurashvili, I.1    Luse, D.S.2
  • 46
    • 0344271983 scopus 로고
    • Prokaryotic and eukaryotic RNA polymerases have homologous core subunits
    • Sweetser, D., Nonet, M., and Young, R.A. (1987). Prokaryotic and eukaryotic RNA polymerases have homologous core subunits. Proc. Natl. Acad. Sci. USA 84, 1192-1196.
    • (1987) Proc. Natl. Acad. Sci. USA , vol.84 , pp. 1192-1196
    • Sweetser, D.1    Nonet, M.2    Young, R.A.3
  • 47
    • 0029029468 scopus 로고
    • Discontinuous movements of DNA and RNA in RNA polymerase accompany formation of a paused transcription complex
    • Wang, D., Meier, T.I., Chan, C.L., Feng, G., Lee, D.N., and Landick, R. (1995). Discontinuous movements of DNA and RNA in RNA polymerase accompany formation of a paused transcription complex. Cell 81, 341-350.
    • (1995) Cell , vol.81 , pp. 341-350
    • Wang, D.1    Meier, T.I.2    Chan, C.L.3    Feng, G.4    Lee, D.N.5    Landick, R.6
  • 48
    • 0026774630 scopus 로고
    • Mechanistic studies of transcriptional arrest at the adenovirus majour late attenuation site
    • Wiest, D.K., Wang, D., and Hawley, D.K. (1992). Mechanistic studies of transcriptional arrest at the adenovirus majour late attenuation site. J. Biol. Chem. 267, 7733-7744.
    • (1992) J. Biol. Chem. , vol.267 , pp. 7733-7744
    • Wiest, D.K.1    Wang, D.2    Hawley, D.K.3
  • 49
    • 0001323636 scopus 로고
    • Transcript elongation and termination in Escherichia coli
    • F.C. Neidhardt, J.L. Ingraham, K.B. Low, B. Magasanik, M. Schaechter, and H.E. Umbarger, eds. (Washington, D.C.: American Society for Microbiology)
    • Yager, T.D., and von Hippel, P.H. (1987). Transcript elongation and termination in Escherichia coli. In Escherichia coli and Salmonella typhimurium, F.C. Neidhardt, J.L. Ingraham, K.B. Low, B. Magasanik, M. Schaechter, and H.E. Umbarger, eds. (Washington, D.C.: American Society for Microbiology), pp. 1241-1275.
    • (1987) Escherichia Coli and Salmonella Typhimurium , pp. 1241-1275
    • Yager, T.D.1    Von Hippel, P.H.2
  • 50
    • 0026084789 scopus 로고
    • A thermodynamic analysis of RNA transcript elongation and termination in E. coli
    • Yager, T.D., and von Hippel, P.H. (1991). A thermodynamic analysis of RNA transcript elongation and termination in E. coli. Biochemistry 30, 1097-1118.
    • (1991) Biochemistry , vol.30 , pp. 1097-1118
    • Yager, T.D.1    Von Hippel, P.H.2
  • 51
    • 0011127275 scopus 로고
    • Gene Q antitermination protein of escherichia coli phages 82 and λ suppress pausing by RNA polymerase at a ρ-dependent terminator and other sites
    • Yang, X., and Roberts, J.W. (1989). Gene Q antitermination protein of Escherichia coli phages 82 and λ suppress pausing by RNA polymerase at a ρ-dependent terminator and other sites. Proc. Natl. Acad. Sci. USA 86, 5301-5305.
    • (1989) Proc. Natl. Acad. Sci. USA , vol.86 , pp. 5301-5305
    • Yang, X.1    Roberts, J.W.2
  • 52
    • 0028962338 scopus 로고
    • Translocation of the escherichia coli transcription complex observed in the registers 11 to 20; "jumping" of RNA polymerase and asymmetric expansion and contraction of the "transcription bubble."
    • Zaychikov, E., Denissova, L., and Heumann, H. (1995). Translocation of the Escherichia coli transcription complex observed in the registers 11 to 20; "jumping" of RNA polymerase and asymmetric expansion and contraction of the "transcription bubble." Proc. Natl. Acad. Sci. USA 92, 1739-1743.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 1739-1743
    • Zaychikov, E.1    Denissova, L.2    Heumann, H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.