Immunocalins: A lipocalin subfamily that modulates immune and inflammatory responses

Biochimica et Biophysica Acta - Protein Structure and Molecular Enzymology

Volumn 1482, Issue 1-2, 2000, Pages 284-297

  Lögdberg, Lennart ^a   Wester, Lena ^b  

^a NEW YORK BLOOD CENTER   (United States)

^b LUND UNIVERSITY   (Sweden)

Author keywords

1 Acid glycoprotein; 1 Microglobulin; Complement factor 8 ; Glycodelin; Immunosuppression; Lipocalin prostaglandin D synthase; Neutrophil gelatinase associated lipocalin; Tear prealbumin

Indexed keywords

ALLERGEN; ALPHA 1 MICROGLOBULIN; COMPLEMENT COMPONENT C8; LIPOCALIN; OROSOMUCOID; PLACENTA PROTEIN 14; PREALBUMIN; PROSTAGLANDIN H2 D ISOMERASE;

ACUTE PHASE RESPONSE; ALLERGY; ANTIINFLAMMATORY ACTIVITY; ANTIMICROBIAL ACTIVITY; HUMAN; IMMUNOMODULATION; INFLAMMATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN FAMILY; REVIEW; THROMBOCYTE FUNCTION;

ACUTE-PHASE REACTION; ADJUVANTS, IMMUNOLOGIC; ANIMAL; ANTI-INFECTIVE AGENTS; ANTI-INFLAMMATORY AGENTS; GLYCOPROTEINS; HUMAN; HYPERSENSITIVITY; MEMBRANE GLYCOPROTEINS; OROSOMUCOID; PREGNANCY PROTEINS; RECEPTORS, CELL SURFACE; SUPPORT, NON-U.S. GOV'T;

MAMMALIA;

EID: 0034684194     PISSN: 01674838     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0167-4838(00)00164-3     Document Type: Review

References (136)

1. 'Lymphokines': non-antibody mediators of cellular immunity generated by lymphocyte activation
2. On soluble mediators of immunological recognition
3. The effect of immunoregulatory alpha-globulin (IRA) upon lymphocytes in vitro
4. 1-Acid glycoprotein
5. 1-Microglobulin: a yellow-brown lipocalin
6. Human neutrophil gelatinase-associated lipocalin and homologous proteins in rat and mouse
7. Human complement protein C8γ
8. Rat probasin: structure and function of an outlier lipocalin
9. Biochemical, structural, genetic, physiological, and pathophysiological features of lipocalin-type prostaglandin D synthase
10. The acute phase reaction syndrome: the acute phase reactants (a review)
11. New insights into the biology of the acute phase response
12. Preparative affinity electrophoresis of different glycoforms of serum glycoproteins: applications for the study of inflammation induced expression of sialyl-Lewis X groups on alpha-1-acid glycoprotein (orosomucoid)
13. Inflammation-induced expression of sialyl Lewis X-containing glycan structures on alpha 1-acid glycoprotein (orosomucoid) in human sera
14. A natural occurring anti-inflammatory molecule?
15. Alpha 1-acid glycoprotein (orosomucoid): pathophysiological changes in glycosylation in relation to its function
16. Occurrence and possible function of inflammation-induced expression of sialyl Lewis-x on acute-phase proteins
17. Oral estrogen treatment induces a decrease in expression of sialyl Lewis x on alpha 1-acid glycoprotein in females and male-to-female transsexuals
18. Transforming growth factor beta 1 influences glycosylation of alpha 1-protease inhibitor in human hepatoma cell lines
19. Glycosylation of four acute-phase glycoproteins secreted by rat liver cells in vivo and in vitro. Effects of inflammation and dexamethasone
20. Effects of monocytic products, recombinant interleukin-1, and recombinant interleukin-6 on glycosylation of alpha 1-acid glycoprotein: studies with primary human hepatocyte cultures and rats
21. A potent enhancer made of clustered liver-specific elements in the transcription control sequences of human alpha 1-microglobulin/bikunin gene
22. Inhibition of platelet aggregation by native and desialised alpha-1 acid glycoprotein
23. Human inter-alpha-inhibitor family in inflammation: simultaneous synthesis of positive and negative acute-phase proteins
24. Hepatic and extra-hepatic transcription of inter-alpha-inhibitor family genes under normal or acute inflammatory conditions in rat
25. The human inter-alpha-trypsin inhibitor genes respond differently to interleukin-6 in HepG2 cells
26. Synthesis of alpha 1-microglobulin in cultured rat hepatocytes is stimulated by interleukin-6, leukemia inhibitory factor, dexamethasone and retinoic acid
27. Alpha-1-microglobulin and bikunin in rats with collagen II-induced arthritis: plasma levels and liver mRNA content
28. Glycodelins: role in regulation of reproduction, potential for contraceptive development and diagnosis of male infertility
29. Glycodelins: biological activity in reproduction and differentiation
30. Identification of neutrophil gelatinase-associated lipocalin as a novel matrix protein of specific granules in human neutrophils
31. Human neutrophil lipocalin (HNL) is a specific granule constituent of the neutrophil granulocyte. Studies in bronchial and lung parenchymal tissue and peripheral blood cells
32. The monitoring of inflammation by specific cellular markers
33. Identification of a new acute phase protein
34. Serum measurements of human neutrophil lipocalin (HNL) discriminate between acute bacterial and viral infections
35. Leukocyte activation detected by increased plasma levels of inflammatory mediators in patients with ischemic cerebrovascular diseases
36. Granulocyte activation markers in induced sputum: comparison between chronic obstructive pulmonary disease, asthma, and normal subjects
37. Respiratory symptoms, bronchial responsiveness, and cellular characteristics of induced sputum in elite swimmers
38. Expression of the complement C8 genes during interleukin-6-mediated in vitro induction of the acute-phase response
39. Identification of a lipocalin in mucosal glands of the human tracheobronchial tree and its enhanced secretion in cystic fibrosis
40. Acute and transient increase of lipocalin-type prostaglandin D synthase (beta-trace) level in cerebrospinal fluid of patients with aneurysmal subarachnoid hemorrhage
41. Expression of lipocalin-type prostaglandin D synthase (beta-trace) in human heart and its accumulation in the coronary circulation of angina patients
42. Protection by alpha 1-acid glycoprotein against tumor necrosis factor-induced lethality
43. Effects of alpha 1-acid glycoprotein in different rodent models of shock
44. Alpha 1-acid glycoprotein and alpha 1-antitrypsin inhibit TNF-induced but not anti-Fas-induced apoptosis of hepatocytes in mice
45. Activation of caspases in lethal experimental hepatitis and prevention by acute phase proteins
46. Alpha-1-acid (AAG, orosomucoid) glycoprotein: interaction with bacterial lipopolysaccharide and protection from sepsis
47. Immunosuppression by human plasma alpha 1-acid glycoprotein: importance of the carbohydrate moiety
48. Lymphocyte stimulation in vitro by orosomucoid glycoprotein
49. Inhibition of neutrophil activation by alpha1-acid glycoprotein
50. Modulation of human polymorphonuclear neutrophil functions by alpha 1-acid glycoprotein
51. Effects of alpha-1 acid glycoprotein on human polymorphonuclear neutrophils: influence of glycan microheterogeneity
52. Alpha 1-acid glycoprotein potentiates lipopolysaccharide-induced secretion of interleukin-1 beta, interleukin-6 and tumor necrosis factor-alpha by human monocytes and alveolar and peritoneal macrophages
53. Alpha 1-acid glycoprotein-induced tumor necrosis factor-alpha secretion of human monocytes is enhanced by serum binding proteins and depends on protein tyrosine kinase activation
54. Prevalence of tri- and tetraantennary glycans of human alpha 1-acid glycoprotein in release of macrophage inhibitor of interleukin-1 activity
55. Antiinflammatory properties of hepatic acute phase proteins: preferential induction of interleukin 1 (IL-1) receptor antagonist over IL-1 beta synthesis by human peripheral blood mononuclear cells
56. Inhibition of platelet aggregation by native and desialised alpha-1 acid glycoprotein
57. Glycosylation of alpha 1-acid glycoprotein in septic shock: changes in degree of branching and in expression of sialyl Lewis(x) groups
58. High-level constitutive expression of alpha 1-acid glycoprotein and lack of protection against tumor necrosis factor-induced lethal shock in transgenic mice
59. Con A-nonreactive human alpha 1-acid glycoprotein (AGP) is more effective in modulation of lymphocyte proliferation than Con A-reactive AGP serum variants
60. Modification of the functional activity of neutrophils treated with acute phase response proteins
61. Selectins: interpreters of cell-specific carbohydrate information during inflammation
62. Do synovial fluid acute phase proteins from patients with rheumatoid arthritis originate from serum?
63. Investigation into the concanavalin A reactivity, fucosylation and oligosaccharide microheterogeneity of alpha 1-acid glycoprotein expressed in the sera of patients with rheumatoid arthritis
64. Modulation of sialyl Lewis X dependent binding to E-selectin by glycoforms of alpha-1-acid glycoprotein expressed in rheumatoid arthritis
65. Effects of low dose methotrexate therapy on the concentration and the glycosylation of alpha 1-acid glycoprotein in the serum of patients with rheumatoid arthritis: a longitudinal study
66. Severe rheumatoid arthritis prohibits the pregnancy-induced decrease in alpha3-fucosylation of alpha1-acid glycoprotein
67. 1-microglobulin
68. Alpha-1-microglobulin is mitogenic for guinea pig lymphocytes
69. 1-microglobulin from man, guinea-pig, rat and rabbit
70. Receptor for alpha1-microglobulin on T lymphocytes: inhibition of antigen-induced interleukin-2 production
71. 1-microglobulin on mouse lymphocytes. Evidence of T and B cell co-operation, B-cell proliferation, and a low affinity receptor on mononuclear cells
72. Alpha-1-microglobulin is mitogenic to human peripheral blood lymphocytes. Regulation by both enhancing and suppressive serum factors
73. Human protein HC and its IgA complex are inhibitors of neutrophil chemotaxis
74. Collagen-bound alpha1-microglobulin in normal and healed tissues and its effect on immunocompetent cells
75. Location and characterization of the three carbohydrate prosthetic groups of human protein HC
76. Alpha-1-microglobulin glycopeptides inhibit antigen-specific stimulation of human peripheral blood leukocytes Scand
77. Human protein HC (alpha-1-microglobulin) and inter-alpha-trypsin inhibitor in connective tissue
78. Alpha-1-microglobulin is found both in blood and in most tissues
79. Bikunin and alpha 1-microglobulin in human zona pellucida and connective tissue
80. Histologic distribution and biochemical properties of alpha-1-microglobulin in human placenta
81. Placental protein 14 functions as a direct T-cell inhibitor
82. Identification of placental protein 14 as an immunosuppressive factor in human reproduction
83. Suppression of lymphocyte reactivity to phytohaemagglutinin by placental protein 14
84. Hematopoietic placental protein 14. An immunosuppressive factor in cells of the megakaryocytic lineage
85. Effect of decidual placental protein 14 on interleukin-2-lymphocyte interactions
86. Placental protein 14 (PP14) inhibits the synthesis of interleukin-2 and the release of soluble interleukin-2 receptors from phytohaemagglutinin-stimulated lymphocytes
87. The effect of human placental protein 14 (PP14) on the production of interleukin-1 from mitogenically stimulated mononuclear cell cultures
88. Suppression by human placental protein 14 of natural killer cell activity
89. Structural analysis of the oligosaccharides derived from glycodelin, a human glycoprotein with potent immunosuppressive and contraceptive activities
90. Molecular characterization and pattern of tissue expression of the gene for neutrophil gelatinase-associated lipocalin from humans
91. Neutrophil gelatinase-associated lipocalin in normal and neoplastic human tissues. Cell type-specific pattern of expression
92. Subcellular localization and translocation of the receptor for N-formylmethionyl-leucyl-phenylalanine in human neutrophils
93. Induction of NGAL synthesis in epithelial cells of human colorectal neoplasia and inflammatory bowel diseases
94. A 25 kDa alpha 2-microglobulin-related protein is a component of the 125 kDa form of human gelatinase
95. Progelatinase B forms from human neutrophils. Complex formation of monomer/lipocalin with TIMP-1
96. Genetic basis of human complement C8 alpha-gamma deficiency
97. Chimeric and truncated forms of human complement protein C8 alpha reveal binding sites for C8 beta and C8 gamma within the membrane attack complex/perforin region
98. Analysis of the specific association of the eight and ninth components of human complement: identification of a direct role for the α subunit of C8
99. Function of subunits within the eight component of human complement: selective removal of the γ chain reveals it has no direct role in cytolysis
100. Expression and characterization of recombinant subunits of human complement component C8: further analysis of the function of C* alpha and C8 gamma
101. Complement component C8gamma is expressed in human fetal and adult kidney independent of C8alpha
102. Tear lipocalin and the eye's front line of defence
103. Tissue expression of tear lipocalin in humans
104. Identification of a lipocalin in mucosal glands of the human tracheobronchial tree and its enhanced secretion in cystic fibrosis
105. Structure and organization of the porcine LCN1 gene encoding Tear lipocalin/von Ebner's gland protein
106. Immunohistochemical localisation of tear lipocalin in human nasal mucosa
107. The salivary lipocalin von Ebner's gland protein is a cysteine proteinase inhibitor
108. Bacterial growth blocked by a synthetic peptide based on the structure of a human proteinase inhibitor
109. Cystatin C, a human proteinase inhibitor, blocks replication of herpes simplex virus
110. Proteins in normal cerebrospinal fluid not found in serum
111. Human brain prostaglandin D synthase has been evolutionarily differentiated from lipophilic-ligand carrier proteins
112. Choroid plexus: the major site of mRNA expression for the beta-trace protein (prostaglandin D synthase) in human brain
113. Identification of a fertility-associated protein in bull seminal plasma as lipocalin-type prostaglandin D synthase
114. Rat prostaglandin D2 synthetase: its tissue distribution, changes during maturation, and regulation in the testis and epididymis
115. Expression of lipocalin-type prostaglandin D synthase (beta-trace) in human heart and its accumulation in the coronary circulation of angina patients
116. Acute and transient increase of lipocalin-type prostaglandin D synthase (beta-trace) level in cerebrospinal fluid of patients with aneurysmal subarachnoid hemorrhage
117. Identification of a thyroid hormone response element in the promoter region of the rat lipocalin-type prostaglandin D synthase (beta-trace) gene
118. Lack of tactile pain (allodynia) in lipocalin-type prostaglandin D synthase-deficient mice
119. Interaction of an acute phase reactant, alpha 1-acid glycoprotein (orosomucoid), with the lymphoid cell surface: a model for non-specific immune suppression
120. The interaction of peripheral blood leukocytes with alpha 1-acid glycoprotein, its carbohydrate chains and neoglycoconjugates
121. Alpha 1-acid glycoprotein (alpha 1-AGP) on the membrane of human lymphocytes: possible involvement in cellular activation
122. Leukocyte surface origin of human alpha 1-acid glycoprotein (orosomucoid)
123. Expression of protein HC on the plasma membrane of different human cell types
124. Identification of the protein HC receptor
125. A receptor for the lipocalin placental protein 14 on human monocytes
126. Allergy to lipocalins: a consequence of misguided T-cell recognition of self and nonself?
127. Nitrophorins and related antihemostatic lipocalins from Rhodnius prolixus and other blood-sucking arthropods
128. Lipocalins as allergens
129. Assignment of tear lipocalin gene to human chromosome 9q34-9qter
130. Comparative mapping of lipocalin genes in human and mouse: the four genes for complement C8γ chain, prostaglandin-D-synthase, oncogene 24p3, and progestagen-associated endometrial protein map to HSA9 and MMU2
131. Structure and sequence relationships in the lipocalins and related proteins