Human complement protein C8γ

Biochimica et Biophysica Acta - Protein Structure and Molecular Enzymology

Volumn 1482, Issue 1-2, 2000, Pages 199-208

  Schreck, Steven F ^a   Parker, Chasta ^a   Plumb, Mnason E ^a   Sodetz, James M ^a  

^a UNIVERSITY OF SOUTH CAROLINA SCHOOL OF MEDICINE   (United States)

Author keywords

C8; C8 ; Cell lysis; Human complement; Membrane attack complex

Indexed keywords

COMPLEMENT COMPONENT C8; COMPLEMENT MEMBRANE ATTACK COMPLEX; LIPOCALIN; PROTEIN SUBUNIT;

BINDING SITE; CYTOLYSIS; HUMAN; PRIORITY JOURNAL; PROTEIN STRUCTURE; PROTEIN SYNTHESIS; REVIEW;

AMINO ACID SEQUENCE; COMPLEMENT 8; COMPLEMENT MEMBRANE ATTACK COMPLEX; GENE DELETION; HUMAN; MOLECULAR SEQUENCE DATA; PROTEIN CONFORMATION; SUPPORT, U.S. GOV'T, P.H.S.;

MYCOBACTERIUM AVIUM COMPLEX (MAC);

EID: 0034684166     PISSN: 01674838     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0167-4838(00)00155-2     Document Type: Review

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5. Structure and function of C8 in the membrane attack sequence of complement
6. The lipocalin protein family: Structure and function
7. Membrane attack complex of complement: Generation of high-affinity phospholipid binding sites by fusion of five hydrophilic plasma proteins
8. Ultrastructure of the membrane attack complex of complement: Heterogeneity of the complex caused by different degree of C9 polymerization
9. Assembly of complement components C5b-8 and C5b-9 on lipid bilayer membranes: Visualization by freeze-etch electron microscopy
10. Structure of the human C7 gene and comparison with the C6, C8A, C8B, and C9 genes
11. Epidermal growth factor-like modules
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14. Purification of functional subunits of the eighth component of human complement (C8) under nondenaturing conditions
15. Function of subunits within the eighth component of human complement: Selective removal of the γ chain reveals it has no direct role in cytolysis
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18. Functional domains of the α-subunit of the eighth component of human complement: Identification and characterization of a distinct binding site for the γ chain
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20. Identity of the segment of human complement C8 recognized by complement regulatory protein CD59
21. Evidence of direct insertion of terminal complement proteins into cell membrane bilayers during cytolysis: Labeling by a photosensitive membrane probe reveals a major role for the eighth and ninth components
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27. The human complement C8G gene, a member of the lipocalin gene family: Polymorphisms and mapping to chromosome 9q34.3
28. Inherited deficiencies of the terminal components of human complement
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33. Crystallographic refinement of human serum retinol binding protein at 2A resolution
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38. Multiple molecular recognition properties of the lipocalin protein family
39. Active sites in complement components C5 and C3 identified by proximity to indels in the C3/4/5 protein family
40. Identification of neutrophil gelatinase-associated lipocalin as a novel matrix protein of specific granules in human neutrophils
41. Effects of the membrane attack complex of complement on nucleated cells