Induction of NGAL synthesis in epithelial cells of human colorectal neoplasia and inflammatory bowel diseases

Gut

Volumn 38, Issue 3, 1996, Pages 414-420

  Nielsen, B S ^a,b   Borregaard, N ^c   Bundgaard, J R ^c   Timshel, S ^a   Sehested, M ^a   Kjeldsen, L ^c  

^a AMAGER HOSPITAL   (Denmark)

^b FINSEN LABORATORY   (Denmark)

^c University of Copenhagen   (Denmark)

Author keywords

Immunohistochemistry; In situ hybridisation; Inflammation; Lipocalin; Neutrophils

Indexed keywords

GELATINASE; LIPOCALIN; SCAVENGER;

ARTICLE; COLORECTAL CANCER; CONTROLLED STUDY; ENTERITIS; EPITHELIUM CELL; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; NEUTROPHIL; PRIORITY JOURNAL;

ACUTE-PHASE PROTEINS; ADENOCARCINOMA; ADENOMA; APPENDICITIS; CARRIER PROTEINS; COLITIS, ULCERATIVE; COLON; COLORECTAL NEOPLASMS; CROHN DISEASE; DIVERTICULITIS, COLONIC; HUMANS; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; INFLAMMATORY BOWEL DISEASES; INTESTINAL MUCOSA; NEOPLASM PROTEINS; ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS; RNA, MESSENGER;

EID: 0029981266     PISSN: 00175749     EISSN: None     Source Type: Journal    
DOI: 10.1136/gut.38.3.414     Document Type: Article

References (38)

1. Pullmann WE, Elsbury S, Kobatasi M, Hapel AJ, Doe WF. Enhanced mucosal cytokine production in inflammatory bowel disease. Gastroenterology 1992; 102: 529-37.
2. Isaacs KL, Balfour Sartor R, Haskill S. Cytokine messenger RNA profiles in inflammatory bowel disease mucosa detected by polymerase chain reaction. Gastroenterology 1992; 103: 1587-95.
3. Ligumsky M, Simon PL, Karmeli F, Rachmilewitz D. Role of interleukin 1 in inflammatory disease - enhanced production during active disease. Gut 1990; 31: 686-9.
4. Cappello M, Keshav S, Prince C, Jewell DP, Gordon S. Detection of mRNAs for macrophage products in inflammatory disease by in situ hybridisation. Gut 1992; 33: 1214-9.
5. Macdonald TT, Hutchings P, Choy M-Y, Murch S, Cooke A. Tumour necrosis factor-alpha and interferon-gamma production measured at the single cell level in normal and inflamed human intestine. Clin Exp Immunol 1990; 81: 301-5.
6. Brynskov J, Tvede N, Andersen CB, Vilien M. Increased concentrations of interleukin 1β, interleukin-2, and soluble interleukin-2 receptors in endoscopical mucosal biopsy specimens with active inflammatory bowel disease. Gut 1992; 33: 55-8.
7. Lauritsen K, Laursen LS, Bukhave K, Rask-Madsen J. In vivo profiles of eicosanoids in ulcerative colitis, Crohn's disease and Clostridium difficile colitis. Gastroenterology 1988; 95: 11-7.
8. Eliakim R, Karmeli F, Razin E, Rachmilewitz D. Role of platelet-activating factor in ulcerative colitis. Gastroenterology 1988; 95: 1167-72.
9. 4 by colonic mucosa in inflammatory bowel disease. Gastroenterology 1984; 86: 453-60.
10. Mazzucchelli L, Hauser C, Zgraggen K, Wagner H, Hess M, Laissue JA, et al. Expression of interleukin-8 gene in inflammatory bowel disease is related to the histological grade of active inflammation. Am J Pathol 1994; 144: 997-1007.
11. Thornton AJ, Streiter RM, Lindley I, Baggiolini M, Kunkel SL. Cytokine-induced gene expression of a neutrophil chemotactic factor/IL-8 in human hepatocytes. J Immunol 1990; 144: 2609-13.
12. Nash S, Stafford J, Madara JL. Effects of polymorphonuclear leukocyte transmigration on the barrier function of cultured intestinal epithelial monolayers. J Clin Invest 1987; 80: 1104-13.
13. Perdue MH, McKay DM. Integrative immunophysiology in the intestinal mucosa. Am J Pathol 1994; 267: G151-65.
14. r 40K protein by DLD-1 colon tumor cells by interferon-gamma. Cell Immunol 1993; 147: 215-21.
15. Bland P. MHC class II expression by the gut epithelium. Immunol Today 1988; 9: 174-8.
16. Kvale D, Brandtzaeg P, Løvhaug D. Up-regulation of the expression of secretory component and HLA molecules in a human colonic cell line by tumour necrosis factor-α and gamma interferon. Scand J Immunol 1988; 28: 351-7.
17. Kelly CP, O'Keane JC, Orellana J, Schroy PC, III, Yang S, LaMont JT, et al. Human colon cancer cells express ICAM-1 in vivo and support LFA-1-dependent lymphocyte adhesion in vitro. Am J Pathol 1992; 263: G864-70.
18. Lammers KM, Jansen J, Bijlsma PB, Ceska M, Tytgat GNJ, Laboisse CL, et al. Polarised interleukin-8 secretion by HT-29/19A cells. Gut 1994; 35: 338-42.
19. Jung HC, Eckmann L, Yang S-K, Panja A, Fierer J, Morzycka-Wroblewska E, et al. A distinct array of proinflammatory cytokines is expressed in human colon epithelial cells in response to bacterial invasion. J Clin Invest 1995; 95: 55-65.
20. Zifroni A, Treves AJ, Sachar DB, Rachmilewitz D. Prostanoid synthesis by cultured intestinal epithelial and mononuclear cells in inflammatory bowel disease. Gut 1983; 24: 659-64.
21. Shannon V, Stenson WF, Holtzman MJ. Induction of epithelial arachidonate 12-lipoxygenase at active sites of inflammatory bowel disease. Am J Pathol 1993; 264: G104-11.
22. Kjeldsen L, Johnsen AH, Sengeløv H, Borregaard N. Isolation and primary structure of NGAL, a novel protein associated with human neutrophil gelatinase. J Biol Chem 1993; 268: 10425-32.
23. Bundgaard JR, Sengeløv H, Borregaard N, Kjeldsen L. Molecular cloning and expression of a cDNA encoding NGAL, A lipocalin expressed in human neutrophils. Biochem Biophys Res Commun 1994; 202: 1468-75.
24. 2-microglobulin-related protein is a component of the 125 kDa form of human gelatinase. FEBS Lett 1992; 314: 386-8.
25. Godovac-Zimmermann J. The structural motif of β-lactoglobulin and retinol-binding protein: a basic framework for binding and transport of small lipophilic molecules? Trends Biochem Sci 1988; 13: 64-6.
26. 1-glycoprotein and serum retinol-binding protein and its relatives. FASEB J 1987; 1: 209-14.
27. Flower DR, North ACT, Attwood TK. Mouse oncogene protein 24p3 is member of the lipocalin family. Biochem Biophys Res Commun 1991; 180: 69-74.
28. Cowan SW, Newcomer ME, Jones TA. Crystallographic refinement of human serum retinol binding protein at 2Å resolution. Proteins: Structure Function and Genetics 1990; 8: 44-61.
29. Sengeløv H, Boulay F, Kjeldsen L, Borregaard N. Subcellular localization and translocation of the receptor for N-formyl-methionyl-leucyl-phenylalanine in human neutrophils. Biochem J 1994; 299: 473-9.
30. Urieli-Shoval S, Meek RL, Hanson RH, Ferguson M, Gordon D, Benditt EP. Preservation of RNA for in situ hybridization: Carnoy's versus formaldehyde fixation. J Histochem Cytochem 1992; 40: 1879-85.
31. Pyke C, Kristensen P, Ralfkiær E, Grøndahl-Hansen J, Eriksen J, Blasi F, et al. Urokinase-type plasminogen activator is expressed in stromal cells and its receptor in cancer cells at invasive foci in human colon adenocarcinomas. Am J Pathol 1991; 138: 1059-67.
32. Beaulieu AD, Paquin R, Rathanaswami P, Mccoll SR. Nuclear signaling in human neutrophils. Stimulation of RNA synthesis is a response to a limited number of proinflammatory agonists. J Biol Chem 1992; 267: 426-32.
33. Botto M, Lissandrini D, Sorio C, Walport M. Biosynthesis and secretion of complement component (C3) by activated human polymorphonuclear leukocytes. J Immunol 1992; 149: 1348-55.
34. Cicco NA, Lindemann A, Content J, Vandenbussche P, Lübbert M, Gauss J, et al. Inducible production of interleukin-6 by human polymorphonuclear neutrophils: role of granulocyte-macrophage colony-stimulating factor and tumor necrosis factor-alpha. Blood 1990; 75: 2049-52.
35. Kjeldsen L, Bainton DF, Sengeløv H, Borregaard N. Identification of neutrophil gelatinase-associated lipocalin as a novel matrix protein of specific granules in human neutrophils. Blood 1994; 83: 799-807.
36. Meheus LA, Fransen LM, Raymackers JG, Blockx HA, van Beeumen JJ, van Bun SM, et al. Identification by microsequencing of lipopolysaccharide-induced proteins secreted by mouse macrophages. J Immunol 1993; 151: 1535-47.
37. Fais S, Pallone F. Ability of human colonic epithelium to express the 4F2 antigen, the common acute lymphoblastic leukemia antigen, and the transferrin receptor. Studies in inflammatory bowel disease and after in vitro exposure to different stimuli. Gastroenterology 1989; 97: 1435-41.
38. Shipp MA, Look AT. Hematopoietic differentiation antigens that are membrane-associated enzymes: cutting is the key. Blood 1993; 82: 1052-70.