Identification of a lipocalin in mucosal glands of the human tracheobronchial tree and its enhanced secretion in cystic fibrosis

Laboratory Investigation

Volumn 78, Issue 9, 1998, Pages 1121-1129

  Redl, Bernhard ^a   Wojnar, Petra ^a   Ellemunter, Helmut ^b   Feichtinger, Hans ^a  

^a UNIVERSITY OF INNSBRUCK   (Austria)

^b INNSBRUCK MEDICAL UNIVERSITY   (Austria)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA; DNA FRAGMENT; LIPOCALIN;

ADOLESCENT; ADULT; AMINO ACID SEQUENCE; ARTICLE; CHILD; CLINICAL ARTICLE; CYSTIC FIBROSIS; FEMALE; HUMAN; HUMAN TISSUE; MALE; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN SECRETION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TRACHEOBRONCHIAL TREE;

ADOLESCENT; ADULT; AMINO ACID SEQUENCE; BASE SEQUENCE; BRONCHI; CARRIER PROTEINS; CHILD; CHILD, PRESCHOOL; CYSTIC FIBROSIS; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MOLECULAR SEQUENCE DATA; MUCOUS MEMBRANE; REFERENCE VALUES; RNA, MESSENGER; TISSUE DISTRIBUTION; TRACHEA;

EID: 0031704524     PISSN: 00236837     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (37)

1. Akerström B and Lödgberg L (1990). An intriguing member of the lipocalin protein family: Alpha 1-microglobulin. Trends Biochem Sci 15:240-243.
2. Anderson MP and Welsh MJ (1990). Fatty acids inhibit apical membrane chloride channel in airway epithelia. Proc Natl Acad Sci USA 87:7334-7338.
3. Bhaskar KR, O'Sullivan DD, Opaskar-Hincman H, and Reid LM (1987). Lipids in airway secretions. Eur J Respir Dis Suppl 71:215-221.
4. Bläker M, Kock K, Ahlers C, Buck F, and Schmale H (1993). Molecular cloning of human von Ebner's gland protein, a member of the lipocalin superfamily highly expressed in lingual salivary glands. Biochim Biophys Acta 1172:131-137.
5. Blaner WS (1989). Retinol binding protein: The serum transport protein for vitamin A. Endocr Rev 10:308-316.
6. Bradford MM (1976). A rapid and sensitive method for the quantification of micrograms of protein utilizing the principle of protein-dye binding. Anal Biochem 72:248-254.
7. Chomczynski P and Sacchi N (1987). Single step method of RNA isolation by guanidinium thiocyanat-phenol-chloroform extraction. Anal Biochem 162:156-159.
8. Dear TN, Campbell K, and Rabbitts TH (1991). Molecular cloning of putative odorant-binding and odorant-metabolizing proteins. Biochemistry 30:10376-10382.
9. Dente L, Pizza MG, Metspalu A, and Cortese R (1987). Structure and expression of genes coding for human alpha 1-acid glycoprotein. EMBO J 6:2289-2296.
10. Don RH, Cox PT, Wainwright BJ, and Mattick JS (1991). "Touchdown" PCR to circumvent spurious priming during gene amplification. Nucleic Acids Res 19:4008.
11. Flower DR (1996). The lipocalin protein family: Structure and function. Biochem J 318:1-14.
12. Frohman MA, Dush MK, and Martin GR (1988). Rapid production of full length cDNAs from rare transcripts: Amplification using a single gene specific oligonucleotide primer. Proc Natl Acad Sci USA 85:8998-9002.
13. Garibotti M, Christiansen H, Schmale H, and Pelosi P (1995). Porcine VEG proteins and tear prealbumins. Chem Senses 20:69-76.
14. Glasgow BJ, Abduragimov AR, Farahakhsh ZT, Faull KF, and Hubbell WL (1995). Tear lipocalins bind a broad array of lipid ligands. Curr Eye Res 14:363-372.
15. Holzfeind P and Redl B (1984). Structural organization of the gene encoding the human lipocalin tear prealbumin and synthesis of the recombinant protein in E. coli. Gene 139: 177-183.
16. Holzfeind P, Merschak P, Rogatsch H, Culig Z, Feichtinger H, Klocker H, and Redl B (1996). Expression of the gene for tear lipocalin/von Ebner's gland protein in human prostate. FEBS Lett 395:95-98.
17. Houdret N, Perini J-M, Galabert C, Scharfman A, Humbert P, Lamblin G, and Roussel P (1986). The high lipid content of respiratory mucins in cystic fibrosis is related to infection. Biochim Biophys Acta 880:54-61.
18. Jacquot J, Hayem A, and Galabert C (1992). Functions of proteins and lipids in airway secretions. Eur Respir J 5:343-358.
19. Kock K, Ahlers C, and Schmale H (1994). Structural organization of the genes for rat von Ebner's gland proteins 1 and 2 reveals their close relationship to lipocalins. Eur J Biochem 221:905-916.
20. Koistinen A, Koistinen R, Dell A, Morris HR, Easton RL, Patankar MS, Oehninger S, Clark GF, and Seppälä M (1996). Glycodelin from seminal plasma is a differentially form of contraceptive glycodelin-A. Mol Hum Reprod 2:759-765.
21. Lassagne H and Gachon AMF (1993). Cloning of a human lacrimal lipocalin secretion in tears. Exp Eye Res 56:605-609.
22. Lichtenberger LM, Graziani LA, Dial EJ, Butter BD, and Hillks BA (1983). Role of surface active phospholipids in gastric cytoprotection. Science 219:1327-1329.
23. Miyawaki A, Matsushita F, Ryo Y, and Mikoshiba K (1994). Possible pheromone-carrier function of two lipocalin proteins in the vomeronasal organ. EMBO J 13:5835-5842.
24. Nagata A, Suzuki Y, Igarashi M, Eguchi N, Toh H, Urade Y, and Hayaishi O (1991). Human brain prostaglandin D synthase has been evolutionarily differentiated from lipophilic-ligand carriers. Proc Natl Acad Sci USA 88:4020-4024.
25. Pervaiz S and Brew K (1985). Homology of β-lactoglobulin, serum retinol-binding protein and protein HC. Science 228: 335-337.
26. Redl B, Holzfeind P, and Lottspeich F (1992). cDNA cloning and sequencing reveals human tear prealbumin to be a member of the lipophilic-ligand carrier protein superfamily. J Biol Chem 267:20282-20287.
27. Riittinen L, Julkunen M, Seppälä M, Koistinen R, and Huhtala M-L (1989). Purification and characterization of endometrial protein PP14 from mid-trimester amniotic fluid. Clin Chim Acta 184:19-29.
28. Sambrook J, Fritsch EF, and Maniatis T (1989). Molecular cloning: A laboratory manual. Cold Spring Harbor, NY: Cold Spring Harbor Press.
29. Sanger F, Nicklen S, and Coulson AR (1977). DNA sequencing with chain-termination inhibitors. Proc Natl Acad Sci USA 74:5463-5467.
30. Sansom CE, North AC, and Sawyer L (1994). Structural analysis and classification of lipocalins and related proteins using a profile-search method. Biochim Biophys Acta 1208: 247-255.
31. Sarosiek J, Slomiany A, Takagi A, and Slomiany BL (1984). Hydrogen ion diffusion in dog gastric mucus glycoproteins: Effect of associated lipids and covalently bound fatty acids. Biochem Biophys Res Commun 118:523-531.
32. Scalfari F, Castagna M, Fattori B, Andreini I, Maremmani C, and Pelosi P (in press, 1998). Expression of a lipocalin in human nasal mucosa. Comp Biochem Physiol [B].
33. Schmale H, Ahlers C, Bläker M, Kock K, and Spielman AI (1993). Perireceptor events in taste. In: Chadwick D, Marsh J, and Goode J, editors. The molecular basis of smell and taste transduction. Ciba Foundation Symposium 179. Chichester, UK: Whiley, 167-185.
34. Selsted ME and Martinez RJ (1983). Isolation and purification of bactericides from human tears. Exp Eye Res 34:305-318.
35. Shaw PH, Held WA, and Hastie MD (1983). The gene family for major urinary proteins: Expression in several secretory tissues of the mouse. Cell 32:755-761.
36. van't Hof W, Blankenvoorde MF, Veerman ECI, and Nieuw Amerongen AV (1997). The salivary lipocalin von Ebner's gland protein is a cysteine proteinase inhibitor. J Biol Chem 272:1837-1841.
37. Widdicombe JG (1987). Role of lipids in airway function. Eur J Respir Dis Suppl 71:197-204.