Effect of supplementary antioxidant vitamin intake on carotid arterial wall intima-media thickness in a controlled clinical trial of cholesterol lowering

Circulation

Volumn 94, Issue 10, 1996, Pages 2369-2372

  Azen, Stanley P ^a   Qian, Dajun ^a   Mack, Wendy J ^a   Sevanian, Alex ^a   Selzer, Robert H ^b   Liu, Chao Ran ^a   Liu, Ci Hua ^a   Hodis, Howard N ^a,c  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^b CALIFORNIA INSTITUTE OF TECHNOLOGY   (United States)

^c UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

antioxidants; atherosclerosis; carotid arteries

Indexed keywords

ALPHA TOCOPHEROL; ANTIOXIDANT; ASCORBIC ACID; COLESTIPOL; NICOTINIC ACID; PLACEBO;

ADULT; ARTERY INTIMA PROLIFERATION; ARTERY MEDIA; ARTICLE; B SCAN; CLINICAL TRIAL; COMMON CAROTID ARTERY; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CORONARY ARTERY ATHEROSCLEROSIS; CORONARY ARTERY BYPASS SURGERY; CORONARY RISK; DIET SUPPLEMENTATION; HUMAN; HYPERCHOLESTEROLEMIA; MAJOR CLINICAL STUDY; MALE; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; RISK MANAGEMENT; STATISTICAL ANALYSIS;

EID: 0029834704     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.CIR.94.10.2369     Document Type: Article

References (27)

1. Westrope KL, Miller RA, Wilson RB. Vitamin E in a rabbit model of endogenous hypercholesterolemia and atherosclerosis. Nutr Rep Intl. 1982;25:83-88.
2. Smith TL, Kummerow FA. Effect of dietary vitamin E on plasma lipids and atherogenesis in restricted ovulator hens. Atherosclerosis. 1989;75:105-109.
3. Janero DR. Therapeutic potential of vitamin E in the pathogenesis of spontaneous atherosclerosis. Free Radic Biol Med. 1991;11:129-144.
4. Verlangieri AJ, Bush MJ. Effects of d-α-tocopherol supplementation on experimentally induced primate atherosclerosis. J Am Coll Nutr. 1992;11:131-138.
5. Stampfer MJ, Hennekens CH, Manson JE, Colditz GA, Rosner B, Willett WC. Vitamin E consumption and the risk of coronary disease in women. N Engl J Med. 1993;328:1444-1449.
6. Rimm EB, Stampfer MJ, Ascherio A, Giovannucci E, Colditz GA, Willett WC. Vitamin E consumption and the risk of coronary disease in men. N Engl J Med. 1993;328:1450-1456.
7. Riemersma RA, Wood DA, Mackintyre CCA, Elton RA, Gey KF, Oliver MF. Risk of angina pectoris and plasma concentrations of vitamins A, C and E and carotene. Lancet. 1991;337:1-5.
8. Gey KF, Puska P, Jordan P, Moser UK. Inverse correlation between plasma vitamin E and mortality from ischemic heart disease in crosscultural epidemiology. Am J Clin Nutr. 1991;53:326S-334S.
9. Enstrom JE, Kanim LE, Klein MA. Vitamin C intake and mortality among a sample of the United States population. Epidemiology. 1992;3:194-202.
10. Blankenhorn DH, Hodis HN. Duff Memorial Lecture: arterial imaging and atherosclerosis reversal. Arteriosclerosis. 1994;14:177-192.
11. Hodis HN, Mack WJ. Risk factor assessment, treatment strategy, and prevention of coronary artery disease: the need for a more rational approach. J Intern Med. 1994;236:111-113.
12. Blankenhorn DH, Johnson RL, Nessim SA, Azen SP, Sanmacro ME, Selzer RH. The Cholesterol Lowering Atherosclerosis Study (CLAS): design, methods, and baseline results. Control Clin Trials. 1987;8:354-387.
13. Blankenhorn DH, Nessim SA, Johnson RL, Sanmacro ME, Azen SP, Cashin-Hemphill L. Beneficial effects of combined colestipol-niacin therapy on coronary atherosclerosis and coronary venous bypass grafts. JAMA. 1987;257:3233-3240.
14. Cashin-Hemphill L, Mack WJ, Pogoda J, Sanmarco ME, Azen SP, Blankenhorn DH. and the CLAS Study Group. Beneficial effects of colestipol-niacin on coronary atherosclerosis: a 4-year follow-up. JAMA. 1990;264:3013-3017.
15. Blankenhorn DH, Selzer RH, Mack WJ, Crawford DW, Pogoda J, Lee PL, Shircore AM, Azen SP. Evaluation of colestipol/niacin therapy with computer-derived coronary end point measures: a comparison of different measures of treatment effect. Circulation. 1992;86:1701-1709.
16. Blankenhorn DH, Azen SP, Crawford DW, Nessim SA, Sanmarco ME, Selzer RH, Shircore AM, Wickham EC. Effects of colestipolniacin therapy on human femoral atherosclerosis. Circulation. 1991;83:438-447.
17. Blankenhorn DH, Selzer RH, Crawford DW, Barth JD, Liu CR, Liu CH, Mack WJ, Alaupovic P. Beneficial effects of colestipol-niacin therapy on the common carotid artery: two- and four-year reduction of intima-media thickness measured by ultrasound. Circulation. 1993;88:20-28.
18. Mack WJ, Selzer RH, Hodis HN, Erickson J, Crawford DW, Liu CR, Liu CH. One-year reduction and longitudinal analysis of carotid intimamedia thickness associated with colestipol-niacin therapy. Stroke. 1993;24:1779-1783.
19. Hodis HN, Mack WJ, LaBree L, Cashin-Hemphill L, Sevanian A, Johnson R, Azen SP. Serial coronary angiographic evidence that antioxidant vitamin intake reduces progression of coronary artery atherosclerosis. JAMA. 1995;273:1849-1854.
20. Selzer RH, Hodis HN, Kwong-Fu H, Mack WJ, Lee PL, Liu CR, Liu CH. Evaluation of computerized edge tracking for quantifying intima-media thickness of the common carotid artery from B-mode ultrasound images. Atherosclerosis. 1994;111:1-11.
21. Pignoli P, Tremoli E, Poli A, Oreste P, Paoletti R. Intimal plus medial thickness of the arterial wall: a direct measurement with ultrasound imaging. Circulation. 1986;74:1399-1406.
22. Johnson RL, Selzer R, Blankenhorn DH, Nessim S, Harlow C, Caldarara L, Azen SP. Nutrient Analysis System: a computerized sevenday food record system. J Am Diet Assoc. 1983;83:667-671.
23. Shircore AM, Mack WJ, Selzer RH, Lee PL, Azen SP, Alaupovic P, Hodis HN. Compensatory vascular changes of remote coronary segments in response to lesion progression as observed by sequential angiography from a controlled clinical trial. Circulation. 1995;92: 2411-2418.
24. Kritchevsky SB, Shimakawa T, Tell GS, Dennis B, Carpenter M, Eckfeldt JH, Peacher-Ryan H, Heiss G. Dietary antioxidants and carotid artery wall thickness: the ARIC study. Circulation. 1995;92:2132-2150.
25. Stephens NG, Parsons A, Schofield PM, Kelly F, Cheeseman K, Mitchinson MJ, Brown MJ. Randomised controlled trial of vitamin E in patients with coronary disease: Cambridge Heart Antioxidant Study (CHAOS). Lancet. 1996;347:781-786.
26. Azen SP, Mack WJ, Cashin-Hemphill L, LaBree L, Shircore AM, Selzer RH, Blankenhorn DH, Hodis HN. Progression of coronary artery disease predicts clinical coronary events: long-term follow-up from the Cholesterol Lowering Atherosclerosis Study (CLAS). Circulation. 1996;93:34-41.
27. The Alpha-Tocopherol, Beta Carotene Cancer Prevention Study Group. The effect of vitamin E and beta carotene on the incidence of lung cancer and other cancers in male smokers. N Engl J Med. 1994;330:1029-1035.