Termination of IL-6-induced STAT activation is independent of receptor internalization but requires de novo protein synthesis

FEBS Letters

Volumn 470, Issue 1, 2000, Pages 15-19

  Thiel, Stefan ^a   Sommer, Ulrike ^a   Kortylewski, Marcin ^a   Haan, Claude ^a   Behrmann, Iris ^a   Heinrich, Peter C ^a   Graeve, Lutz ^a  

^a RWTH AACHEN UNIVERSITY   (Germany)

Author keywords

Desensitization; Endocytosis; gp130; Interleukin 6; Jak STAT signaling

Indexed keywords

INTERLEUKIN 6;

ARTICLE; CELL PROLIFERATION; COMPLEX FORMATION; DESENSITIZATION; ENDOCYTOSIS; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; INTERNALIZATION; LIGAND BINDING; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN SYNTHESIS INHIBITION; RECEPTOR BINDING; RECEPTOR DOWN REGULATION; SIGNAL TRANSDUCTION;

ANIMALS; ANTIGENS, CD; CELL LINE; CYTOKINE RECEPTOR GP130; DNA-BINDING PROTEINS; ENDOCYTOSIS; ERYTHROPOIETIN; HUMANS; INTERLEUKIN-6; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MEMBRANE GLYCOPROTEINS; MICE; PHOSPHORYLATION; PROTEIN-TYROSINE-PHOSPHATASE; RECEPTORS, INTERLEUKIN-6; SHP1 PROTEIN TYROSINE PHOSPHATASE; STAT1 TRANSCRIPTION FACTOR; STAT3 TRANSCRIPTION FACTOR; TRANS-ACTIVATORS; TUMOR CELLS, CULTURED;

EID: 0034677738     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-5793(00)01276-X     Document Type: Article

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