Dopaminergic neurotoxins, 6,7-dihydroxy-1-(3',4'-dihydroxybenzyl)- isoquinolines, cause different types of cell death in SH-SY5Y cells: Apoptosis was induced by oxidized papaverolines and necrosis by reduced tetrahydropapaverolines

Neuroscience Letters

Volumn 291, Issue 2, 2000, Pages 89-92

  Maruyama, Wakako ^a   Sango, Kumiko ^b   Iwasa, Kinuko ^c   Minami, Chiyoko ^b   Dostert, Philippe ^d   Kawai, Masao ^b   Moriyasu, Masataka ^c   Naoi, Makoto ^b  

^a Lab of Biochemistry and Metabolism   (Japan)

^b NAGOYA INSTITUTE OF TECHNOLOGY   (Japan)

^c KOBE PHARMACEUTICAL UNIVERSITY   (Japan)

^d Biotrial SA   (France)

Author keywords

6,7 Dihydroxy 1 (3',4'dihydroxyenzyl) isoquinoline; Adenosine triphosphate; Apoptosis; Necrosis; Papaveroline; Parkinson's disease

Indexed keywords

6,7 DIHYDROXY 1 (3',4' DIHYDROXYBENZYL)ISOQUINOLINE; ADENOSINE TRIPHOSPHATE; HOE 33342; ISOQUINOLINE DERIVATIVE; NEUROTOXIN; PAPAVEROLINE; PROPIDIUM IODIDE; TETRAHYDROPAPAVEROLINE; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CONTROLLED STUDY; DOPAMINERGIC SYSTEM; DRUG CYTOTOXICITY; DRUG MECHANISM; HUMAN; HUMAN CELL; NEUROTOXICITY; PARKINSON DISEASE; PRIORITY JOURNAL;

APOPTOSIS; CELL DEATH; DOPAMINE; HUMANS; NECROSIS; NEUROBLASTOMA; NEUROTOXINS; OXIDATION-REDUCTION; TETRAHYDROPAPAVEROLINE; TUMOR CELLS, CULTURED;

EID: 0034666297     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3940(00)01381-1     Document Type: Article

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