A three-dimensional perspective on exon binding by a group II self-splicing intron

EMBO Journal

Volumn 19, Issue 18, 2000, Pages 5007-5018

  Costa, Maria ^a,b   Michel, François ^a,b   Westhof, Eric ^c  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b CNRS   (France)

^c INSTITUT DE BIOLOGIE MOLÉCULAIRE ET CELLULAIRE   (France)

Author keywords

Group II intron; Hydroxyl radical probing; Intron exon interactions; Ribozyme; RNA structure modeling

Indexed keywords

ARTICLE; BINDING SITE; EXON; GENE STRUCTURE; INTRON; MOLECULAR GENETICS; PRIORITY JOURNAL; RNA SPLICING; STRUCTURE ANALYSIS;

EID: 0034665039     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/19.18.5007     Document Type: Article

References (38)

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3. Defining functional groups, core structural features and inter-domain tertiary contacts essential for group II intron self-splicing: A NAIM analysis
4. Complete sequence of the mitochondrial DNA of the red alga Porphyra purpurea. Cyanobacterial introns and shared ancestry of red and green algae
5. Ribbons 2.0
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8. Catalytic site components common to both splicing steps of a group II intron
9. An RNA conformational change between the two chemical steps of group II self-splicing
10. Branch-point attack in group II introns is a highly reversible transesterification, providing a potential proofreading mechanism for 5'-splice site selection
11. Inferring consensus structure from nucleic acid sequences
12. Frequent use of the same tertiary motif by self-folding RNAs
13. Tight binding of the 5' exon to domain I of a group II self-splicing intron requires completion of the intron active site
14. Multiple tertiary interactions involving domain II of group II self-splicing introns
15. A group II self-splicing intron from the brown alga Pylaiella littoralis is active at unusually low magnesium concentrations and forms populations of molecules with a uniform conformation
16. Differential chemical probing of a group II self-splicing intron identifies bases involved in tertiary interactions and supports an alternative secondary structure model of domain V
17. Unexpected metal ion requirements specific for catalysis of the branching reaction in a group II intron
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20. Group II intron endonucleases use both RNA and protein subunits for recognition of specific sequences in double-stranded DNA
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28. Defining the inside and outside of a catalytic RNA molecule
29. MANIP: An interactive tool for modelling RNA
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32. Comparative and functional anatomy of group II catalytic introns - A review
33. Rules for DNA target-site recognition by a lactococcal group II intron enable retargeting of the intron to specific DNA sequences
34. Catalytically critical nucleotides in domain 5 of a group II intron
35. Model for an RNA tertiary interaction from the structure of an intermolecular complex between a GAAA tetraloop and an RNA helix
36. The two steps of group II intron self-splicing are mechanistically distinguishable
37. Crystallographic refinement of yeast aspartic acid transfer RNA
38. Sequence specificity of a group II intron ribozyme: Multiple mechanisms for promoting unusually high discrimination against mismatched targets