Sequence specificity of a group II intron ribozyme: Multiple mechanisms for promoting unusually high discrimination against mismatched targets

Biochemistry

Volumn 37, Issue 11, 1998, Pages 3839-3849

  Xiang, Qing ^a   Qin, Peter Zhifeng ^b   Michels, William J ^a,c   Freeland, Keri ^b   Pyle, Anna Marie ^a  

^a Columbia Univ Coll Phys Surgs ^*  (United States)

^b Columbia University ^*  (United States)

^c University of California Berkeley   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

RIBOZYME;

ARTICLE; BASE MISPAIRING; CATALYSIS; CONTROLLED STUDY; ENERGY TRANSFER; ENZYME CONFORMATION; ENZYME KINETICS; ENZYME SPECIFICITY; INTRON; PRIORITY JOURNAL; RNA SPLICING;

BASE COMPOSITION; BASE SEQUENCE; BINDING SITES; ENERGY TRANSFER; INTRONS; KINETICS; MUTAGENESIS, SITE-DIRECTED; NUCLEIC ACID CONFORMATION; OLIGODEOXYRIBONUCLEOTIDES; RNA, CATALYTIC; SUBSTRATE SPECIFICITY;

FELIS CATUS;

EID: 0032539968     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi972661n     Document Type: Article

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