L-Arginine in coronary atherosclerosis

International Journal of Cardiology

Volumn 75, Issue 2-3, 2000, Pages 123-128

  Tentolouris, Costas ^a   Tousoulis, Dimitris ^a,c   Goumas, George ^a   Stefanadis, Christodoulos ^a   Davies, Graham ^b   Toutouzas, Pavlos ^a  

^a UNIVERSITY OF ATHENS MEDICAL SCHOOL   (Greece)

^b HAMMERSMITH HOSPITAL   (United Kingdom)

^c NONE   (Greece)

Author keywords

Atherosclerosis; Endothelium; L arginine; Nitric oxide

Indexed keywords

ACETYLCHOLINE; ARGININE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; OXYGEN;

ARTERY DILATATION; ARTERY ENDOTHELIUM; CIGARETTE SMOKING; CLINICAL TRIAL; CORONARY ARTERY ATHEROSCLEROSIS; CORONARY ARTERY BLOOD FLOW; CORONARY RISK; DIABETES MELLITUS; DISEASE ASSOCIATION; DRUG MECHANISM; HUMAN; HYPERCHOLESTEROLEMIA; HYPERTENSION; MEDIATOR RELEASE; NONHUMAN; PERCUTANEOUS TRANSLUMINAL ANGIOPLASTY; PRIORITY JOURNAL; REVIEW;

ARGININE; CORONARY ARTERIOSCLEROSIS; ENDOTHELIUM, VASCULAR; HUMANS; HYPERCHOLESTEROLEMIA; RISK FACTORS; SMOKING; VASODILATION;

EID: 0034664922     PISSN: 01675273     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0167-5273(00)00320-X     Document Type: Review

References (60)

1. Vascular endothelial cells synthesize nitric oxide from L-arginine
2. Nitric oxide modulates epicardial coronary basal vasomotor tone in awake dogs
3. Cloning of inducible nitric oxide synthase in rat vascular smooth muscle cells
4. A specific inhibitor of nitric oxide formation from L-arginine attenuates endothelium-dependent relaxation
5. 2+-independent nitric oxide synthase in the myocardium
6. Biochemical mechanisms underlying vascular smooth muscle relaxation: The granulate cyclase-cyclic GMP system
7. Inhibition of nitric oxide synthesis in septic shock: How much is beneficial?
8. Isoforms of nitric oxide synthase: Characterisation and purification from different cell types
9. Mechanisms of nitric release from the vascular endothelium
10. Nitric oxide: Physiology, pathology and pharmacology
11. Nitric oxide and another potent vasodilator are formed by NG-hydroxy-L-arginine by cultured endothelial cells
12. Argininase activity in endothelial cells: Inhibition by NG-hydroxy-L-arginine during high output NO production
13. Induction of nitric oxide synthase by cytokine in vascular smooth muscle cells
14. Differential regulation of L-arginine transport and nitric oxide production by vascular smooth muscle and endothelium
15. Effect of increased availability of endothelium-derived nitric oxide precursor on endothelium-dependent vascular relaxation in normal subjects and in patients with essential hypertension
16. Effects of L- and D-arginine on the basal tone of human diseased coronary arteries and their responses to substance P
17. Effects of L-arginine supplementation on endothelium-dependent coronary vasodilation in patients with angina pectoris and normal coronary angiograms
18. Correction of endothelial dysfunction in coronary microcirculation of hypercholesterolemic patients by L-arginine
19. Endothelial dysfunction in hypercholesterolemia is reversed by nutritional product designed to enhance nitric oxide activity
20. Effects of L-arginine on forearm vessels and responses to acetylcholine
21. Effects of dietary L-arginine on atherosclerosis and endothelium-dependent vasodilation in the hypercholesterolemic rabbit: Response according to treatment duration, anatomic site, and sex
22. L-arginine augments endothelium-dependent vasodilation in cholesterol-fed rabbits
23. L-arginine prevents xanthoma development and inhibits atherosclerosis in LDL receptor knockout mice
24. Anti-atherogenic effects of L-arginine in hypercholesterolemic rabbit
25. Arginine restores nitric oxide activity and inhibits monocyte accumulation after vascular injury in hypercholesterolemic rabbits
26. Dietary L-arginine reduces the progression of atherosclerosis in cholesterol-fed rabbits: Comparison with lovastatin
27. Regression or progression. Dependency on vascular nitric oxide
28. Coronary stenosis dilation induced by L-arginine
29. Does acute improvement of endothelial dysfunction in coronary artery disease improve myocardial ischemia? A double-blind comparison of parenteral D- and L-arginine
30. Effect of L-arginine on coronary endothelial function in cardiac transplant recipients. Relation to vessel wall morphology
31. Effect of L-arginine on human coronary endothelial-dependent and physiologic vasodilation
32. Oral L-arginine improves endothelium-dependent dilation in hypercholesterolaemic young adults
33. Enhanced endothelial adhesiveness in hypercholesterolemia is attenuated by L-arginine
34. Oral L-arginine in patients with coronary disease on medical management
35. Effect of L-arginine on acetylcholine-induced endothelium-dependent vasodilation differs between the coronary and forearm vasculatures in humans
36. Effects of dietary L-arginine on atherosclerosis and endothelium-dependent vasodilation in the hypercholesterolemic rabbit: Response according to treatment duration, anatomic site, and sex
37. L-arginine improves endothelium-dependent vasodilation in hypercholesterolemic humans
38. Endogenous nitric oxide synthase inhibitor. A novel marker of atherosclerosis
39. Serum cholesterol level smoking and vasomotor responses to L-arginine in diseased epicardial coronary arteries
40. Arginine restores cholinergic relaxation of hypercholesterolemic rabbit thoracic aorta
41. Restoring vascular nitric oxide formation by L-arginine improves the symptoms of intermittent claudication in patients with peripheral arterial occlusive disease
42. Dilator actions of arginine in human peripheral vasculature
43. Effects of acute administration of L-arginine in coronary atherosclerosis
44. Effects of infusion of L-arginine into the left anterior descending coronary artery on acetylcholine-induced vasoconstriction of human atheromatous coronary arteries
45. L-arginine administration enhances the endothelium-dependent dilation in atherosclerotic arteries and stenoses
46. Effects of changing the availability of the substrate for nitric oxide synthase by L-arginine on coronary vasomotor tone in angina patients with angiographically narrowed and in patients with angiographically normal coronary arteries
47. Long-term cigarette smoking impairs endothelium-dependent coronary artery vasodilator function
48. Lipid peroxidation of circulating low density lipoproteins with age, smoking and in peripheral vascular disease
49. Increased adhesiveness of isolated monocytes to endothelium is prevented by vitamin C intake in smokers
50. Antioxidant vitamin C improves endothelial dysfunction in chronic smokers
51. L-arginine normalizes coronary vasomotion in long-term smokers
52. Nitric oxide, an endothelial cell relaxation factor, Inhibits neutrophil superoxide anion production via a direct action on NADPH oxidase
53. Inducible NO synthase is present within human atherosclerotic lesions and promotes the formation and activity of peroxynitrite
54. Production of hydroxyl radicals from the simultaneous generation of superoxide and nitric oxide
55. Effect of potassium on vasodilation to acetylcholine in essential hypertension
56. Defective L-arginine-nitric oxide pathway in offspring of essential hypertensive patients
57. Impairment of coronary vascular reserve and Ach-induced coronary vasodilation in diabetic patients with angiographically normal coronary arteries and normal left ventricular systolic function
58. Impaired neurogenic and endothelium-mediated relaxation of penile smooth muscle from diabetes men with impotence
59. Inhibition and stimulation of nitric oxide synthesis in the human forearm arterial bed of patients with insulin-dependent diabetes
60. Coronary artery responses to physiolocal stimuli are improved by deferoxamine but not by L-arginine in non-insulin-dependent diabetic patients with angiographically normal coronary arteries and no other risk factors