Activation of antigen-specific CD4+ Th2 cells and B cells in vivo increases norepinephrine release in the spleen and bone marrow

Journal of Immunology

Volumn 165, Issue 2, 2000, Pages 725-733

  Kohm, Adam P ^a   Tang, Yueming ^a   Sanders, Virginia M ^a   Jones, Stephen B ^a  

^a LOYOLA UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA 2 ADRENERGIC RECEPTOR; CD4 ANTIGEN; CHLORISONDAMINE; HEMOCYANIN; NORADRENALIN;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; B LYMPHOCYTE ACTIVATION; BONE MARROW CELL; CELL PROLIFERATION; CONTROLLED STUDY; FEMALE; MOLECULAR CLONING; MOUSE; NONHUMAN; NORADRENALIN RELEASE; POSTGANGLIONIC NERVE; PRIORITY JOURNAL; SPLEEN CELL; T LYMPHOCYTE ACTIVATION;

EID: 0034661985     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.165.2.725     Document Type: Article

References (46)

1. Clark, E. A., and J. A. Ledbetter. 1994. How B and T cells talk to each other. Nature 367:425.
2. Ader, R., D. Felten, and N. Cohen. 1990. Interactions between the brain and the immune system. Annu. Rev. Pharmacol. Toxicol 30:561.
3. Besedovsky, H. O., and A. Del Rey. 1992. Immune-neuroendocrine circuits: integrative role of cytokines. Front. Neuroendocrinol. 13:61.
4. Goehler, L. E., J. K. Relton, D. Dripps, R. Kiechle, N. Tartaglia, S. F. Maier, and L. R. Watkins. 1997. Vagal paraganglia bind biotinylated interleukin-1 receptor antagonist: a possible mechanism for immune-to-brain communication. Brain Res. Bull. 43:357.
5. Calvo, W. 1968. The innervation of the bone marrow in laboratory animals. J. Anat. 123:315.
6. Reilly, F. D., P. A. McCuskey, M. L. Miller, R. S. McCuskey, and H. A. Meineke. 1979. Innervation of the periarteriolar lymphatic sheath of the spleen. Tissue Cell 11:121.
7. Williams, J. M., and D. L. Felten. 1981. Sympathetic innervation of murine thymus and spleen: a comparative histofluorescence study. Anat. Rec. 199:531.
8. Kohm, A. P., and V. M. Sanders. 1999. Suppression of antigen-specific Th2 cell-dependent IgM and IgGI production following norepinephrine depletion in vivo. J. Immunol 162:5299.
9. 2-adrenergic receptor by Th1 and Th2 clones: implications for cytokine production and B cell help. J. Immunal. 158:4200.
10. 2-adrenergic receptor: a mechanism for selective modulation of Th1 cell cytokine production. J. Immunol. 159:4857.
11. Glowinski, J., and R. J. Baldessarini. 1966. Metabolism of norepinephrine in the central nervous system. Pharmacol. Rev. 18:1201.
12. Tang, Y., R. Shankar, R. Gamelli, and S. Jones. 1999. Dynamic norepinephrine alterations in bone marrow: evidence of functional innervation. J. Neuroimmunol. 96:182.
13. Pardini, B. J., S. B. Jones, and J. P. Filkins. 1983. Cardiac and splenic norepinephrine turnovers in endotoxic rats. Am. J. Physiol 245:H276.
14. Jones, S. B., M. F. Kovarik, and F. D. Romano. 1986. Cardiac and splenic norepinephrine turnover during septic peritonitis. Am. J. Physiol. 250:R892.
15. Del Rey, A., H. O. Besedovsky, E. Sorkin, M. Da Prada, and S. Arrenbrecht. 1981. Immunoregulation mediated by the sympathetic nervous system II. Cell. Immunol. 63:329.
16. Besedovsky, H. O., A. Del Rey, E. Sorkin, M. Da Prada, and H. H. Keller. 1979. Immunoregulation mediated by the sympathetic nervous system. Cell. Immunol. 48:346.
17. Fuchs, B. A., K. S. Campbell, and A. E. Munson. 1988. Norepinephrine and serotonin content of the murine spleen: its relationship to lymphocyte β-adrenergic receptor density and the humoral immune response in vivo and in vitro. Cell, Immunol. 117:339.
18. Herzyk, D. J., J. N. Allen, C. B. Marsh, and M. D. Wewers. 1992. Macrophage and monocyte IL-1β regulation differs at multiple sites: messenger RNA expression, translation, and post-translational processing. J. Immunol. 149:3052.
19. Herriott, M. J., H. Jiang, C. A. Stewart, D. J. Fast, and R. W. Leu. 1993. Mechanistic differences between migration inhibitory factor (MIF) and IFN-γ for macrophage activation: MIF and IFN-γ synergize with lipid A to mediate migration inhibition but only IFN-γ induces production of TNF-α and nitric oxide. J. Immunol. 150:4524.
20. Wang, J., and A. J. Dunn. 1999. The role of interleukin-6 in the activation of the hypothalamo-pituitary-adrenocortical axis and brain indoleamines by endotoxin and interleukin-1β. Brain Res 815:337.
21. Shimizu, N., T. Hori, and H. Nakane. 1994. An interleukin-1-β-induced noradrenaline release in the spleen is mediated by brain corticotropin-releasing factor: an in vivo microdialysis study in conscious rats. Brain Behav. Immun. 7:14.
22. Ruhl, A., S. Hurst, and S. M. Collins. 1994. Synergism between interleukins 1β and 6 on noradrenergic nerves in rat myenteric plexus. Gastroenterology 107: 993.
23. Bosma, G. C., R. P. Custer, and M. J. Bosma. 1983. A severe combined immunodeficiency mutation in the mouse. Nature 301:527.
24. Brodie, B. B., E. Costa, A. Dlabac, N. H. Neff, and H. H. Smookler. 1978. Application of steady state kinetics to the estimation of synthesis rate and turnover times of tissue catecholamines. J. Pharmacol Exp. Ther. 154:493.
25. 3H]NE in the rate heart. J. Pharmacol. Exp. Ther. 160:48.
26. Snow, E. C., E. S. Vitetta, and J. W. Uhr. 1983. Activation of antigen-enriched B cells. 1. Purification and response to thymus-independent antigens. J. Immunol. 130:607.
27. Myers, C. D., V. M. Sanders, and E. S. Vitetta. 1986. Isolation of antigen-binding virgin and memory B cells. J. Immunol. Methods 92:45.
28. Vitetta, E. S., A. Bossie, R. Fernandez-Botran, C. D. Myers, K. G. Oliver, V. M. Sanders, and T. L. Stevens. 1987. Interaction and activation of antigen-specific T and B cells. Immunol. Rev. 99:193.
29. Costa, E., and N. H. Neff. 1970. Estimation of turnover rates to study the metabolic regulation of the steady-state levels of neuronal monoamines. In Handbook of Neurochemistiy. A. Lajtha, ed. Plenum Press, New York, pp. 45-90.
30. Snedecor, G. W., and W. G. Cochron. Statistical Methods. Iowa State University Press, Ames.
31. Felten, S. Y., D. L. Felten, D. L. Bellinger, S. L. Carlson, K. D. Ackerman, K. S. Madden, J. A. Olschowka, and S. Livnat. 1988. Noradrenergic sympathetic innervation of lymphoid organs. Prog Allergy 43:14.
32. Kouassi, E., W. Boukhris, J. Descotes, P. Zukervar, Y. S. Li, and J. P. Revillard. 1987. Selective T cell defects induced by dopamine administration in mice. Immunopharmacol. Immunotoxicol. 9:477.
33. Sanders, V. M., J. M. Snyder, J. W. Uhr, and E. S. Vitetta. 1986. Characterization of the physical interaction between antigen-specific B and T cells. J. Immunol. 137:2395.
34. Kawakami, K., and D. C. Parker. 1993. Antigen and helper T lymphocytes activate B lymphocytes by distinct signaling pathways. Eur. J. Immunol. 23:77.
35. Sapolsky, R., C. Rivier, G. Yamamoto, P. Plotsky, and W. Vale. 1987. Interleukin-1 stimulates the secretion of hypothalamic corticotropin-releasing factor Science 238:522.
36. Fleshner, M., L. Silbert, T. Deak, L. E. Goehler, D. Martin, L. R. Watkins, and S. F. Maier. 1997. TNF-α-induced corticosterone elevation but not serum protein or corticosteroid binding globulin reduction is vagally mediated. Brain Res. Bull. 44:701.
37. Besedovsky, H., A. Del Rey, E. Sorkin, M. Da Prada, R. Burri, and C. Honegger. 1983. The immune response evokes changes in brain noradrenergic neurons. Science 221:564.
38. Neumann, H., H. Schmidt, E. Wilharm, L. Behrens, and H. Wekerle. 1997. Interferon γ gene expression in sensory neurons: evidence for autocrine gene regulation. J. Exp. Med. 186:2023.
39. Bai, Y., and R. P. Hart. 1998. Cultured sympathetic neurons express functional interleukin-1 receptors. J. Neuroimmunol. 91:43.
40. Marz, P., J. G. Cheng, R. A. Gadient, P. H. Patterson, T. Stoyan, U. Otten, and S. Rose-John. 1998. Sympathetic neurons can produce and respond to interleukin 6. Proc. Natl. Acad. Sci. USA 95:3251.
41. Eneroth, A., K. Kristensson, A. Ljungdahl, and T. Olsson. 1991. Interferon-γ-like immunoreactivity in developing rat spinal ganglia neurons in vivo and in vitro. J. Neurocytol 20:225.
42. Flamand, V., D. Abramowicz, M. Goldman, C. Biernaux, G. Huez, J. Urbain, M. Moser, and O. Leo. 1990. Anti-CD3 antibodies induce T cells from unprimed animals to secrete IL-4 both in vitro and in vivo. J. Immunol. 144:2875.
43. Swain, S. L. 1994. Generation and in vivo persistence of polarized Th1 and Th2 memory cells. Immunity 1:543.
44. Mosmann, T. R., H. Cherwinski, M. W. Bond, M. A. Giedlin, and R. L. Coffman. 1986. Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins. J. Immunol. 136:2348.
45. Cherwinski, H. M., J. H. Schumacher, K. D. Brown, and T. R. Mosmann. 1987. Two types of mouse helper T cell clone. III. Further differences in lymphokine synthesis between Th1 and Th2 clones revealed by RNA hybridization, functionally monospecific bioassays, and monoclonal antibodies. J. Exp. Med. 166:1229.
46. Madden, K. S., V. M. Sanders, and D. L. Felten. 1995. Catecholamine influences and sympathetic neural modulation of immune responsiveness. Annu. Rev. Pharmacol. Toxicol. 35:417.