TNF-α-induced corticosterone elevation but not serum protein or corticosteroid binding globulin reduction is vagally mediated

Brain Research Bulletin

Volumn 44, Issue 6, 1997, Pages 701-706

  Fleshner, M ^a   Silbert, L ^a   Deak, T ^a   Goehler, L E ^a   Martin, D ^b   Watkins, L R ^a   Maier, S F ^a  

^a UNIVERSITY OF COLORADO   (United States)

^b AMGEN INC   (United States)

Author keywords

CBG; Corticosterone; Cytokine; TNF; Vagotomy; Vagus

Indexed keywords

CORTICOSTERONE; INTERLEUKIN 1 RECEPTOR; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; RECOMBINANT TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ARTICLE; BRAIN; CONTROLLED STUDY; IMMUNE RESPONSE; IMMUNOSTIMULATION; INFLAMMATION; INTRAPERITONEAL DRUG ADMINISTRATION; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; RAT; SENSORY NERVE; VAGOTOMY; VAGUS NERVE;

ANIMALS; BLOOD PROTEINS; CORTICOSTERONE; ELECTROSHOCK; INJECTIONS, INTRAPERITONEAL; MALE; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, INTERLEUKIN-1; TRANSCORTIN; TUMOR NECROSIS FACTOR-ALPHA; VAGOTOMY; VAGUS NERVE;

EID: 0030713271     PISSN: 03619230     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0361-9230(97)00258-X     Document Type: Article

References (32)

1. Banks W. A., Oritz L., Plotkin S. R., Kastin A. J. Human interleukin (IL) 1 alpha, murine IL-1 alpha, and murine IL-1 beta are transported from blood to brain in the mouse by a shared saturable mechanism. J. Pharmacol. Exp. Ther. 259:1991;988-996.
2. Baumann H., Gauldie J. The acute phase response. Immunol. Today. 15:1994;74-81.
3. Besedovsky H. O., del Rey A., Sorkin E., Dinarello C. A. Immunoregulatory feedback between interleukin-1 and glucocorticoid hormones. Science. 233:1986;652-654.
4. Bluthé R. M., Walter V., Pamet P., Layé S., Lestage J., Verrier D., Poole S., Stenning B. E., Kelly K. W., Dantzer R. Lipopolysaccharide induces sickness behaviour by a vagal mediated mechanism. C. R. Acad. Sci. Ser. III Sci. Vie. 317:1994;499-503.
5. Bradford M. M. A rapid and sensitive method for quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72:1976;248-254.
6. Brady L. S., Lynn A. B., Herkenham M., Gottesfeld Z. Systemic interleukin-1 induces early and late patterns of c-fos mRNA expression in brain. J. Neurosci. 14:1994;4951-4964.
7. Bret-Dibat J. L., Bluthe R. M., Kent S., Kelly K. W., Dantzer R. Lipopolysaccharide and interleukin-1 depress food-motivated behavior in mice by a vagal-mediated mechanism. Brain Behav. Immunol. 9:1995;242-246.
8. Dinarello C. A. Interleukin-1 and interleukin-1 antagonism. Blood. 77:1991;1627-1652.
9. Dinarello C. A. Interleukin-1 and its biologically related cytokines. Adv. Immunol. 44:1989;153-205.
10. Dunn A. J. Endotoxin-induced activation of cerebral catecholamine and serotonin metabolism Comparison with interleukin-1 . J. Pharmacol. Exp. Ther. 261:1992;964-969.
11. Dunn A. J. Role of cytokines in infection-induced stress. Ann. NY Acad. Sci. 697:1993;189-202.
12. Fleshner M., Goehler L. E., Hermann J., Relton J. K., Watkins L. R., Maier S. F. Interleukin-1b induced corticosterone elevation and hypothalamic NE depletion is vagally mediated. Brain Res. Bull. 37:1995;605-610.
13. Gaykema R. P. A., Dykstra I., Tilders F. J. H. Subdiaphragmatic vagotomy suppresses endotoxin-induced activation of hypothalamic CRH neurons and ACTH secretion. Endocrinology. 136:1995;4717-4720.
14. Ghezzi P. TNF and the liver. Beutler B. Tumor necrosis factor. 1992;87-116 Raven Press, New York.
15. Goehler L. E., Busch C. R., Tartaglia N., Relton J., Sisk D., Maier S. F., Watkins L. R. Blockade of cytokine induced conditioned taste aversion by subdiaphragmatic vagotomy Further evidence for vagal mediation of immune-brain communication . Neurosci. Lett. 185:1995;163-166.
16. Goehler L. E., Relton J. K., Dripps D., Kiechle R., Tartaglia N., Maier S. F., Watkins L. R. Vagal paraganglia bind biotinylated interleukin-1 receptor antagonist (IL-1ra) in the rat A possible mechanism for immune-to-brain communication . Brain Res. Bull. 43:1997;357-364.
17. Hagan R. M., Poole S., Bristow A. F. CRH as a mediator of the acute-phase response in rats, mice, and rabbits. J. Endocrinol. 136:1993;207-216.
18. Hart B. L. Biological basis of the behavior of sick animals. Neurosci. Biobehav. Rev. 12:1988;123-137.
19. Hasko G., Elendov I. J., Kvetan V., Vizi E. S. Differential effect of selective block of α2-adrenoreceptors on plasma levels of tumour necrosis factor-α, interleukin-6 and corticosterone induced by bacterial lipopolysaccaride in mice. J. Endocrinol. 144:1995;457-462.
20. Kent S., Bluthé R.-M., Kelley K. W., Dantzer R. Sickness behavior as a new target for drug development. Trends Pharmacol. Sci. 13:1992;24-28.
21. Linthorst A. C. E., Flachskamm C., Holsboer F., Reul J. M. H. M. Local administration of recombinant human interleukin-1B in the rat hippocampus increases serotonergic neurotransmission, hypothalamic-pituitary-adrenocortical axis activity, and body temperature. Endocrinology. 135:1994;520-532.
22. Maier, S. F.; Goehler, L. E.; Fleshner, M.; Watkins, L. R. The role of the vagus nerve in cytokine-to-brain communication. Ann. NY Acad. Sci. (in press).
23. Nijima A. The afferent discharges from sensors for IL-1 in the hepatoportal system in the anesthetized rat. J. Physiol. 446:1992;236P.
24. Rivest S., Torres G., Rivier C. Differential effects of central and peripheral injection of interleukin-1 on brain c-fos expression and neuroendocrine functions. Brain Res. 587:1992;13-23.
25. Rokita H., Pierzchalski P., Stalinska K. Changes in IL-6 receptor subunit mRNA expression in primary mouse hepatocyte cultures and murine and rat hepatoma cell lines. Ann. NY Acad. Sci. 762:1995;465-467.
26. Saper C. B., Breder C. D. The neurologic basis of fever. N. Eng. J. Med. 330:1994;1880-1886.
27. Van Dam A.-M., Brown M., Man-A-Hing W., Berkenbosch F. Immunocytochemical detection of prostaglandin E2 in microvasculature and in neurons of rat brain after administration of bacterial endotoxin. Brain Res. 613:1993;331-336.
28. Watkins L. R., Goehler L. E., Relton J. K., Tartaglia N., Silbert L., Martin D., Maier S. F. Blockade of interleukin-1 induced fever by subdiaphragmatic vagotomy Evidence for vagal mediation of immune-brain communication . Neurosci. Lett. 183:1994;1-5.
29. Watkins L. R., Wiertelak E. P., Goehler L., Mooney-Heiberger K., Martinez J., Furness L., Smith K. P., Iadorola M. J., Maier S. F. Neurocircuitry of illness-induced hyperalgesia. Brain Res. 639:1994;283-299.
30. Watkins L. R., Goehler L. E., Relton J., Brewer M. T., Maier S. F. Mechanisms of TNF-induced hyperalgesia. Brain Res. 692:1995;244-250.
31. Westphal O. Steroid-protein interactions. 1971;Springer Verlag, New York.
32. Zalcman S., Green-Johnson J. M., Murray L., Nance D. M., Dyck D., Anisman H., Greenberg A. H. Cytokine-specific central monoamine alterations induced by interleukin-1, -2 and -6. Brain Res. 643:1994;40-49.