Transcriptional control in myelinating glia: The basic recipe

GLIA

Volumn 29, Issue 2, 2000, Pages 118-123

  Wegner, Michael ^a,b  

^a UNIVERSITY OF HAMBURG   (Germany)

^b ZMNH   (Germany)

Author keywords

Charcot Marie Tooth disease; Egr; Gtx; Krox; Oligodendrocyte; Pax; Pelizaeus Merzbacher disease; POU; Schwann cell; SCIP; Sox

Indexed keywords

HIGH MOBILITY GROUP PROTEIN; HOMEODOMAIN PROTEIN; TRANSCRIPTION FACTOR; ZINC FINGER PROTEIN;

ANIMAL; BIOSYNTHESIS; CYTOLOGY; GENE EXPRESSION REGULATION; GENETICS; GLIA; HUMAN; METABOLISM; MOUSE; MYELIN SHEATH; PHYSIOLOGY; REVIEW;

ANIMALS; GENE EXPRESSION REGULATION; HIGH MOBILITY GROUP PROTEINS; HOMEODOMAIN PROTEINS; HUMANS; MICE; MYELIN SHEATH; NEUROGLIA; TRANSCRIPTION FACTORS; ZINC FINGERS;

EID: 0034651020     PISSN: 08941491     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1098-1136(20000115)29:2<118::AID-GLIA4>3.0.CO;2-Q     Document Type: Review

References (31)

1. Armstrong RC, Kim JG, Hudson LD. 1995. Expression of myelin transcription factor I (MyTI), a "zinc-finger" DNA-binding protein, in developing oligodendrocytes. Glia 14:303-321.
2. Arroyo EJ, Bermingham JR, Rosenfeld MG, Scherer SS. 1998. Promyelinating Schwann cells express Tst-1/SCIP/Oct-6. J Neurosci 18: 7891-7902.
3. Awatramani R, Scherer S, Grinspan J, Collarini E, Skoff R, O'Hagan D, Garbern J, Kamholz J. 1997. Evidence that the homeodomain protein Gtx is involved in the regulation of oligodendrocyte myelination. J Neurosci 17:6657-6668.
4. Bermingham JR, Scherer SS, O'Connell S, Arroyo E, Kalla KA, Powell FL, Rosenfeld MG. 1996. Tst-1/Oct-6/SCIP regulates a unique step in peripheral myelination and is required for normal respiration. Genes Dev 10:1751-1762.
5. Blanchard AD, Sinanan A, Parmantier E, Zwart R, Broos L, Meijer D, Meier C, Jessen KR, Mirsky R. 1996. Oct-6 (SCIP/Tst-1) is expressed in Schwann cell precursors, embryonic Schwann cells, and postnatal myelinating Schwann cells: comparison with Oct-1, Krox-20, and Pax-3. J Neurosci Res 46:630-640.
6. Collarini EJ, Kuhn R, Marshall CJ, Monuki ES, Lemke G, Richardson WD. 1992. Down-regulation of the POU transcription factor SCIP is an early event in oligodendrocyte differentiation in vitro. Development 116:193-200.
7. Herbarth B, Pingault V, Bondurand N, Kuhlbrodt K, Hermans-Borgmeyer I, Puliti A, Lemort N, Goossens M, Wegner M. 1998. Mutation of the Sry-related Sox10 gene in Dominant megacolon, a mouse model for human Hirschsprung disease. Proc Natl Acad Sci USA 95:5161-5165.
8. Inoue K, Tanabe Y, Lupski JR. 1999. Myelin deficiencies in both the central and peripheral nervous system associated with a Sox10 mutation. Ann Neurol 46:313-318.
9. Jaegle M, Mandemakers W, Broos L, Zwart R, Karis A, Visser P, Grosveld F, Meijer D. 1996. The POU factor Oct-6 and Schwann cell differentiation. Science 273:507-510.
10. Jaegle M, Meijer D. 1998. Role of Oct-6 in Schwann cell differentiation. Microsc Res Tech 41:372-378.
11. Jensen NA, Pedersen KM, Celis JE, West MJ. 1998. Neurological disturbances, premature lethality, and central myelination deficiency in transgenic mice overexpressing the homeodomain transcription factor Oct-6. J Clin Invest 101:1292-1299.
12. Kioussi C, Gross MK, Gruss P. 1995. Pax3: a paired domain gene as a regulator in PNS myelination. Neuron 15:553-562.
13. Komuro I, Schalling M, Jahn L, Bodmer R, Jenkins NA, Copeland NG, Izumo S. 1993. Gtx: a novel murine homeobox-containing gene, expressed specifically in glial cells of the brain and germ cells of testis, has a transcriptional repressor activity in vitro for a serum-inducible promoter. EMBO J 12:1387-1401.
14. Kuhlbrodt K, Herbarth B, Sock E, Enderich J, Hermans-Borgmeyer I, Wegner M. 1998a. Cooperative function of POU proteins and Sox proteins in glial cells. J Biol Chem 273:16050-16057.
15. Kuhlbrodt K, Herbarth B, Sock E, Hermans-Borgmeyer I, Wegner M. 1998b. Sox10, a novel transcriptional modulator in glial cells. J Neurosci 18:237-250.
16. Monuki ES, Weinmaster G, Kuhn R, Lemke G. 1989. SCIP: a glial POU domain gene regulated by cyclic AMP. Neuron 3:783-793.
17. Pingault V, Bondurand N, Kuhlbrodt K, Goerich DE, Prehu M-O, Puliti A, Herbarth B, Hermans-Borgmeyer I, Legius E, Matthijs G, Amiel J, Lyonnet S, Ceccherini I, Romeo G, Smith JC, Read AP, Wegner M, Goossens M. 1998. Sox10 mutations in patients with Waardenburg-Hirschsprung disease. Nat Genet 18:171-173.
18. Pott U, Colello RJ, Schwab ME. 1996. A new Cys2/His2 zinc finger gene, rKr1, expressed in oligodendrocytes and neurons. Mol Brain Res 38:109-121.
19. Pott U, Thiesen HJ, Colello RJ, Schwab ME. 1995. A new Cys2/His2 finger gene, rKr2, is expressed in differentiated rat oligodendrocytes and encodes a protein with a functional repressor domain. J Neurochem 65:1955-1966.
20. Read AP, Newton VE. 1997. Waardenburg syndrome. J Med Genet 34:656-665.
21. Renner K, Leger H, Wegner M. 1994. The POU-domain protein Tst-1 and papovaviral T-antigen function synergistically to stimulate glia-specific gene expression of JC virus. Proc Natl Acad Sci USA 91:6433-6437.
22. Schreiber J, Enderich J, Sock E, Schmidt C, Richter-Landsberg C, Wegner M. 1997. Redundancy of class III POU proteins in the oligodendrocyte lineage. J Biol Chem 272:32286-32293.
23. Sock E, Leger H, Kuhlbrodt K, Schreiber J, Enderich J, Richter-Landsberg C, Wegner M. 1997. Expression of Krox proteins during differentiation of the O2-A progenitor cell line CG-4. J Neurochem., 68:1911-1919.
24. Southard-Smith EM, Kos L, Pavan WJ. 1998. Sox10 mutation disrupts neural crest development in Dom Hirschsprung mouse model. Nat Genet 18:60-64.
25. Stewart HJS. 1995. Expression of c-Jun, Jun B, Jun D, and cAMP response element binding protein by Schwann cells and their precursors in vivo and in vitro. Eur J Neurosci 7:1366-1375.
26. Topilko P, Levi G, Merlo G, Mantero S, Desmarquet C, Mancardi G, Charnay P. 1997. Differential regulation of the zinc finger genes Krox-20 and Krox-24 (Egr-1) suggests antagonistic roles in Schwann cells. J Neurosci Res 50:702-712.
27. Topilko P, Schneider MS, Levi G, Baron VEA, Chennoufi AB, Seitanidou T, Babinet C, Charnay P. 1994. Krox-20 controls myelination in the peripheral nervous system. Nature 371:796-799.
28. Warner LE, Mancias P, Butler IJ, McDonald CM, Keppen L, Koob KG, Lupski J. 1998. Mutations in the early growth response 2 (EGR2) gene are associated with hereditary myelinopathies. Nat Genet 18:382-384.
29. Weinstein DE, Burrola PG, Lemke G. 1995. Premature Schwann cell differentiation and hypermyelination in mice expressing a targeted antagonist of the POU transcription factor SCIP. Mol Cell Neurosci 6:212-229.
30. Zorick TS, Syroid DE, Arroyo E, Scherer SS, Lemke G. 1996. The transcription factors SCIP and Krox-20 mark distinct stages and cell fates in Schwann cell differentiation. Mol Cell Neurosci 8:129-145.
31. Zorick TS, Syroid DE, Brown A, Gridley T, Lemke G. 1999. Krox-20 controls SCIP expression, cell cycle exit and susceptibility to apoptosis in developing myelinating Schwann cells. Development 126:1397-1406.