PIN domains in nonsense-mediated mRNA decay and RNAi

Current Biology

Volumn 10, Issue 24, 2000, Pages R888-R890

  Clissold, Patricia M ^a   Ponting, Chris P ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CAENORHABDITIS ELEGANS PROTEIN; EXONUCLEASE; FUNGAL PROTEIN; HELMINTH PROTEIN; MESSENGER RNA; NMD2 PROTEIN, S CEREVISIAE; PHOSPHOPROTEIN; RIBONUCLEASE H; RNA; SACCHAROMYCES CEREVISIAE PROTEIN; SMG 2 PROTEIN, C ELEGANS; SMG-2 PROTEIN, C ELEGANS; TRANSACTIVATOR PROTEIN;

AMINO ACID SEQUENCE; ANIMAL; ARTICLE; CHEMICAL STRUCTURE; CHEMISTRY; FACTUAL DATABASE; GENETICS; HUMAN; METABOLISM; MOLECULAR GENETICS; PROTEIN TERTIARY STRUCTURE; SEQUENCE ALIGNMENT;

AMINO ACID SEQUENCE; ANIMALS; CAENORHABDITIS ELEGANS PROTEINS; DATABASES, FACTUAL; EXONUCLEASES; FUNGAL PROTEINS; HELMINTH PROTEINS; HUMANS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PHOSPHOPROTEINS; PROTEIN STRUCTURE, TERTIARY; RIBONUCLEASE H, CALF THYMUS; RNA; RNA, MESSENGER; SACCHAROMYCES CEREVISIAE PROTEINS; SEQUENCE ALIGNMENT; TRANS-ACTIVATORS;

EID: 0034649546     PISSN: 09609822     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-9822(00)00858-7     Document Type: Review

References (29)

1. Mechanisms of mRNA surveillance in eukaryotes
2. RNA surveillance: Unforeseen consequences for gene expression, inherited genetic disorders and cancer
3. RNA interference: Genetic wand and genetic watchdog
4. Double-stranded RNA as a template for gene silencing
5. Unwinding RNA in Saccharomyces cerevisiae: DEAD-box proteins and related families
6. A link between RNA interference and nonsense-mediated decay in Caenorhabditis elegans
7. A new kind of informational suppression in the nematode Caenorhabditis elegans
8. smg-7 is required for mRNA surveillance in Caenorhabditis elegans
9. Upf1p control of nonsense mRNA translation is regulated by Nmd2p and Upf3p
10. Novel elF4G domain homologues linking mRNA translation with nonsense-mediated mRNA decay
11. Eukaryote-specific domains in translation initiation factors: Implications for translation regulation and evolution of the translation system
12. Gapped BLAST and PSI-BLAST: A new generation of protein database search programs
13. The Est1 subunit of yeast telomerase binds the Tlc1 telomerase RNA
14. Telomere length regulation and telomeric chromatin require the nonsense-mediated mRNA decay pathway
15. Comparative genomics of the Archaea (Euryarchaeota): Evolution of conserved protein families, the stable core, and the variable shell
16. Identification of a novel component of the nonsense-mediated mRNA decay pathway by use of an interacting protein screen
17. Structure-specific DNA cleavage by 5′ nucleases
18. Removing near neighbour redundancy from large protein sequence collections
19. Crystal structure of Thermus aquaticus DNA polymerase
20. Structure of bacteriophage T4 RNase H, a 5′ to 3′ RNA-DNA and DNA-DNA exonuclease with sequence similarity to the RAD2 family of eukaryotic proteins
21. Coordination between the polymerase and 5′-nuclease components of DNA polymerase I of Escherichia coli
22. Functional analysis of point mutations in human flap endonuclease-1 active site
23. Premature translational termination triggers mRNA decapping
24. ATP is a cofactor of the Upf1 protein that modulates its translation termination and RNA binding activities
25. SMG-2 is a phosphorylated protein required for mRNA surveillance in Caenorhabditis elegans and related to Upf1p of yeast
26. An RNA-directed nuclease mediates post-transcriptional gene silencing in Drosophila cells
27. Prediction of protein secondary structure at better than 70% accuracy
28. A workbench for multiple alignment construction and analysis
29. Biochemical and mutational studies of the 5′-3′ exonuclease of DNA polymerase I of Escherichia coli